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5Y4P
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BU of 5y4p by Molmil
Crystal structure of Trypanosoma cruzi spermidine synthase in complex with 5-methoxy-2-(5-methyl-4,5-dihydro-1H-imidazol-2-yl)phenol
Descriptor: 5'-[(S)-(3-AMINOPROPYL)(METHYL)-LAMBDA~4~-SULFANYL]-5'-DEOXYADENOSINE, 5-methoxy-2-[(5R)-5-methyl-4,5-dihydro-1H-imidazol-2-yl]phenol, Spermidine synthase, ...
Authors:Amano, Y, Tateishi, Y.
Deposit date:2017-08-04
Release date:2018-08-08
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Discovery of a Hidden Trypanosoma cruzi Spermidine Synthase Binding Site and Inhibitors through In Silico, In Vitro , and X-ray Crystallography.
Acs Omega, 8, 2023
7BYT
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BU of 7byt by Molmil
Crystal structure of exo-beta-1,3-galactanase from Phanerochaete chrysosporium Pc1,3Gal43A with galactose
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ...
Authors:Matsuyama, K, Ishida, T, Kishine, N, Fujimoto, Z, Igarashi, K, Kaneko, S.
Deposit date:2020-04-24
Release date:2020-11-04
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Unique active-site and subsite features in the arabinogalactan-degrading GH43 exo-beta-1,3-galactanase from Phanerochaete chrysosporium .
J.Biol.Chem., 295, 2020
1WMZ
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BU of 1wmz by Molmil
Crystal Structure of C-type Lectin CEL-I complexed with N-acetyl-D-galactosamine
Descriptor: 2-acetamido-2-deoxy-alpha-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-galactopyranose, CALCIUM ION, ...
Authors:Sugawara, H, Kusunoki, M, Kurisu, G, Fujimoto, T, Aoyagi, H, Hatakeyama, T.
Deposit date:2004-07-22
Release date:2004-09-07
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Characteristic Recognition of N-Acetylgalactosamine by an Invertebrate C-type Lectin, CEL-I, Revealed by X-ray Crystallographic Analysis
J.Biol.Chem., 279, 2004
1WMY
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BU of 1wmy by Molmil
Crystal Structure of C-type Lectin CEL-I from Cucumaria echinata
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, lectin CEL-I, ...
Authors:Sugawara, H, Kusunoki, M, Kurisu, G, Fujimoto, T, Aoyagi, H, Hatakeyama, T.
Deposit date:2004-07-22
Release date:2004-09-07
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Characteristic Recognition of N-Acetylgalactosamine by an Invertebrate C-type Lectin, CEL-I, Revealed by X-ray Crystallographic Analysis
J.Biol.Chem., 279, 2004
6EQJ
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BU of 6eqj by Molmil
Crystal Structure of Human Glycogenin-1 (GYG1) Tyr195pIPhe mutant, apo form
Descriptor: 1,2-ETHANEDIOL, Glycogenin-1
Authors:Bailey, H.J, Kopec, J, Bilyard, M.K, Bezerra, G.A, Seo Lee, S, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Davis, B.G, Yue, W.W.
Deposit date:2017-10-13
Release date:2017-12-20
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Palladium-mediated enzyme activation suggests multiphase initiation of glycogenesis.
Nature, 563, 2018
6FWZ
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BU of 6fwz by Molmil
Crystal structure of human UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase (DPAGT1) (V264G mutant) in complex with UDP-GlcNAc
Descriptor: (2S)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(6E)-HEXADEC-6-ENOYLOXY]PROPYL (8E)-OCTADEC-8-ENOATE, MAGNESIUM ION, UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase, ...
Authors:Pike, A.C.W, Dong, Y.Y, Chu, A, Tessitore, A, Goubin, S, Dong, L, Mukhopadhyay, S, Mahajan, P, Chalk, R, Berridge, G, Wang, D, Kupinska, K, Belaya, K, Beeson, D, Burgess-Brown, N, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC)
Deposit date:2018-03-07
Release date:2018-07-25
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structures of DPAGT1 Explain Glycosylation Disease Mechanisms and Advance TB Antibiotic Design.
Cell, 175, 2018
6FM9
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BU of 6fm9 by Molmil
Crystal structure of human UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase (DPAGT1)
Descriptor: (2S)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(6E)-HEXADEC-6-ENOYLOXY]PROPYL (8E)-OCTADEC-8-ENOATE, UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase
Authors:Pike, A.C.W, Dong, Y.Y, Chu, A, Tessitore, A, Goubin, S, Dong, L, Mukhopadhyay, S, Mahajan, P, Chalk, R, Berridge, G, Wang, D, Kupinska, K, Belaya, K, Beeson, D, Burgess-Brown, N, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC)
Deposit date:2018-01-30
Release date:2018-02-28
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structures of DPAGT1 Explain Glycosylation Disease Mechanisms and Advance TB Antibiotic Design.
Cell, 175, 2018
3QYS
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BU of 3qys by Molmil
Room Temperature X-ray Structure of D-Xylose Isomerase in complex with 0.6Ni2+ cation bound in M2 metal binding site at pH=5.8
Descriptor: NICKEL (II) ION, Xylose isomerase
Authors:Kovalevsky, A.Y, Hanson, L, Langan, P.
Deposit date:2011-03-03
Release date:2011-08-17
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Identification of the Elusive Hydronium Ion Exchanging Roles with a Proton in an Enzyme at Lower pH Values.
Angew.Chem.Int.Ed.Engl., 50, 2011
3QZA
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BU of 3qza by Molmil
Joint neutron and X-ray structure of apo-D-Xylose Isomerase at pH=5.9
Descriptor: Xylose isomerase, deuterium(1+)
Authors:Kovalevsky, A.Y, Hanson, L, Langan, P.
Deposit date:2011-03-04
Release date:2011-08-17
Last modified:2023-09-13
Method:NEUTRON DIFFRACTION (2 Å), X-RAY DIFFRACTION
Cite:Identification of the Elusive Hydronium Ion Exchanging Roles with a Proton in an Enzyme at Lower pH Values.
Angew.Chem.Int.Ed.Engl., 50, 2011
2E5D
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BU of 2e5d by Molmil
Crystal structure of Human NMPRTase complexed with nicotinamide
Descriptor: NICOTINAMIDE, Nicotinamide phosphoribosyltransferase
Authors:Takahashi, R, Nakamura, S, Kobayashi, Y, Ohkubo, T.
Deposit date:2006-12-20
Release date:2007-12-25
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and reaction mechanism of human nicotinamide phosphoribosyltransferase
J.Biochem., 147, 2010
2E5C
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BU of 2e5c by Molmil
Crystal structure of Human NMPRTase complexed with 5'-phosphoribosyl-1'-pyrophosphate
Descriptor: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, Nicotinamide phosphoribosyltransferase
Authors:Takahashi, R, Nakamura, S, Kobayashi, Y, Ohkubo, T.
Deposit date:2006-12-20
Release date:2007-12-25
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure and reaction mechanism of human nicotinamide phosphoribosyltransferase
J.Biochem., 147, 2010
6EQL
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BU of 6eql by Molmil
Crystal Structure of Human Glycogenin-1 (GYG1) Tyr195pIPhe mutant complexed with manganese and UDP
Descriptor: 1,2-ETHANEDIOL, Glycogenin-1, MANGANESE (II) ION, ...
Authors:Bailey, H.J, Kopec, J, Bilyard, M.K, Bezerra, G.A, Seo Lee, S, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Davis, B.G, Yue, W.W.
Deposit date:2017-10-13
Release date:2017-12-20
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Palladium-mediated enzyme activation suggests multiphase initiation of glycogenesis.
Nature, 563, 2018
2E5B
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BU of 2e5b by Molmil
Crystal structure of Human NMPRTase as free-form
Descriptor: Nicotinamide phosphoribosyltransferase
Authors:Takahashi, R, Nakamura, S, Kobayashi, Y, Ohkubo, T.
Deposit date:2006-12-20
Release date:2007-12-25
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and reaction mechanism of human nicotinamide phosphoribosyltransferase
J.Biochem., 147, 2010
3H6F
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BU of 3h6f by Molmil
Crystal Structure of Mycobacterium Tuberculosis Proteasome Modified by inhibitor HT1171
Descriptor: DIMETHYLFORMAMIDE, Proteasome (Alpha subunit) PrcA, Proteasome (Beta subunit) PrcB
Authors:Li, D, Li, H, Lin, G.
Deposit date:2009-04-23
Release date:2009-09-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Inhibitors selective for mycobacterial versus human proteasomes.
Nature, 461, 2009
4J2R
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BU of 4j2r by Molmil
Middle domain of influenza A virus RNA-dependent polymerase PB2
Descriptor: Polymerase basic protein 2
Authors:Qiu, H, Tsurumura, T, Tsumori, Y, Hatakeyama, D, Kuzuhara, T, Tsuge, H.
Deposit date:2013-02-05
Release date:2014-02-05
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Crystallization and preliminary X-ray diffraction studies of a surface mutant of the middle domain of PB2 from human influenza A (H1N1) virus
ACTA CRYSTALLOGR.,SECT.F, 70, 2014
3H6I
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BU of 3h6i by Molmil
Crystal Structure of Mycobacterium Tuberculosis Proteasome Modified by inhibitor GL1
Descriptor: DIMETHYLFORMAMIDE, Proteasome (Alpha subunit) PrcA, Proteasome (Beta subunit) PrcB
Authors:Li, D, Li, H, Lin, G.
Deposit date:2009-04-23
Release date:2009-09-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Inhibitors selective for mycobacterial versus human proteasomes.
Nature, 461, 2009
3HFA
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BU of 3hfa by Molmil
Crystal Structure of Mycobacterium Tuberculosis Proteasome open-gate mutant
Descriptor: DIMETHYLFORMAMIDE, Proteasome (Alpha subunit) PrcA, Proteasome (Beta subunit) PrcB
Authors:Li, D, Li, H.
Deposit date:2009-05-11
Release date:2009-09-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.504 Å)
Cite:Inhibitors selective for mycobacterial versus human proteasomes.
Nature, 461, 2009
3HF9
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BU of 3hf9 by Molmil
Crystal Structure of Mycobacterium Tuberculosis Proteasome open-gate mutant modified by inhibitor GL1
Descriptor: Proteasome (Alpha subunit) PrcA, Proteasome (Beta subunit) PrcB
Authors:Li, D, Li, H.
Deposit date:2009-05-11
Release date:2009-09-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.878 Å)
Cite:Inhibitors selective for mycobacterial versus human proteasomes.
Nature, 461, 2009
1IW0
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BU of 1iw0 by Molmil
Crystal structure of a heme oxygenase (HmuO) from Corynebacterium diphtheriae complexed with heme in the ferric state
Descriptor: Heme oxygenase, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ...
Authors:Hirotsu, S, Unno, M, Chu, G.C, Lee, D.S, Park, S.Y, Shiro, Y, Ikeda-Saito, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2002-04-04
Release date:2003-04-08
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The crystal structures of the ferric and ferrous forms of the heme complex of HmuO, a heme oxygenase of Corynebacterium diphtheriae.
J.Biol.Chem., 279, 2004
1YNR
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BU of 1ynr by Molmil
Crystal structure of the cytochrome c-552 from Hydrogenobacter thermophilus at 2.0 resolution
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Cytochrome c-552, HEME C, ...
Authors:Travaglini-Allocatelli, C, Gianni, S, Dubey, V.K, Borgia, A, Di Matteo, A, Bonivento, D, Cutruzzola, F, Bren, K.L, Brunori, M.
Deposit date:2005-01-25
Release date:2005-05-17
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:An Obligatory Intermediate in the Folding Pathway of Cytochrome c552 from Hydrogenobacter thermophilus
J.Biol.Chem., 280, 2005
1IW1
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BU of 1iw1 by Molmil
Crystal structure of a heme oxygenase (HmuO) from Corynebacterium diphtheriae complexed with heme in the ferrous state
Descriptor: Heme oxygenase, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ...
Authors:Hirotsu, S, Unno, M, Chu, G.C, Lee, D.S, Park, S.Y, Shiro, Y, Ikeda-Saito, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2002-04-04
Release date:2003-04-04
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The crystal structures of the ferric and ferrous forms of the heme complex of HmuO, a heme oxygenase of Corynebacterium diphtheriae.
J.Biol.Chem., 279, 2004
2DKN
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BU of 2dkn by Molmil
Crystal structure of the 3-alpha-hydroxysteroid dehydrogenase from Pseudomonas sp. B-0831 complexed with NADH
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 3-alpha-hydroxysteroid dehydrogenase
Authors:Nakamura, S.
Deposit date:2006-04-12
Release date:2006-08-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Apo- and Holo-structures of 3{alpha}-Hydroxysteroid Dehydrogenase from Pseudomonas sp. B-0831: LOOP-HELIX TRANSITION INDUCED BY COENZYME BINDING
J.Biol.Chem., 281, 2006
5YOQ
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BU of 5yoq by Molmil
Human serum albumin complexed with sodium 4-phenylbutyrate
Descriptor: 4-PHENYL-BUTANOIC ACID, PHOSPHATE ION, Serum albumin
Authors:Kawai, A, Otagiri, M.
Deposit date:2017-10-30
Release date:2018-02-07
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Crystal structure analysis of human serum albumin complexed with sodium 4-phenylbutyrate.
Biochem Biophys Rep, 13, 2018
1WLK
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BU of 1wlk by Molmil
L122E mutant of FMN-binding protein from Desulfovibrio vulgaris (Miyazaki F)
Descriptor: FLAVIN MONONUCLEOTIDE, FMN-binding protein
Authors:Shibata, N, Higuchi, Y.
Deposit date:2004-06-28
Release date:2005-07-19
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Determination of the role of the Carboxyl-terminal leucine-122 in FMN-binding protein by mutational and structural analysis.
J.Biochem., 141, 2007
1WLI
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BU of 1wli by Molmil
L122Y mutant of FMN-binding protein from Desulfovibrio vulgaris (Miyazaki F)
Descriptor: FLAVIN MONONUCLEOTIDE, FMN-binding protein
Authors:Shibata, N, Higuchi, Y.
Deposit date:2004-06-28
Release date:2005-07-19
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Determination of the role of the Carboxyl-terminal leucine-122 in FMN-binding protein by mutational and structural analysis.
J.Biochem., 141, 2007

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