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4OX9
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BU of 4ox9 by Molmil
Crystal structure of the aminoglycoside resistance methyltransferase NpmA bound to the 30S ribosomal subunit
Descriptor: 16S rRNA, 16S rRNA (adenine(1408)-N(1))-methyltransferase, 30S ribosomal protein S10, ...
Authors:Dunkle, J.A, Conn, G.L, Dunham, C.M.
Deposit date:2014-02-04
Release date:2014-04-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.8035 Å)
Cite:Molecular recognition and modification of the 30S ribosome by the aminoglycoside-resistance methyltransferase NpmA.
Proc.Natl.Acad.Sci.USA, 111, 2014
2NP6
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BU of 2np6 by Molmil
Crystal structure of the adenine-specific DNA methyltransferase M.TaqI complexed with the cofactor analog AETA and a 10 bp DNA containing an abasic site analog at the target position
Descriptor: 5'-D(*GP*AP*CP*AP*TP*CP*GP*(6MA)P*AP*C)-3', 5'-D(*GP*TP*TP*CP*GP*(3DR)P*TP*GP*TP*C)-3', 5'-DEOXY-5'-[2-(AMINO)ETHYLTHIO]ADENOSINE, ...
Authors:Lenz, T, Scheidig, A.J, Weinhold, E.
Deposit date:2006-10-26
Release date:2007-11-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Caught in the act II: Visualization of an intermediate in the DNA base-flipping pathway induced by the adenine-specific DNA methyltransferase M.TaqI
To be Published
2NP7
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BU of 2np7 by Molmil
Crystal structure of the adenine-specific DNA methyltransferase M.TaqI complexed with the cofactor analog AETA and a 10 bp DNA containing an abasic site analog at the target position and pyrrolo-dC at the target base partner position
Descriptor: 5'-D(*GP*AP*CP*AP*(4PC)P*CP*GP*(6MA)P*AP*C)-3', 5'-D(*GP*TP*TP*CP*GP*(3DR)P*TP*GP*TP*C)-3', 5'-DEOXY-5'-[2-(AMINO)ETHYLTHIO]ADENOSINE, ...
Authors:Lenz, T, Scheidig, A.J, Weinhold, E.
Deposit date:2006-10-26
Release date:2007-11-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Caught in the act II: Visualization of an intermediate in the DNA base-flipping pathway induced by the adenine-specific DNA methyltransferase M.TaqI
To be Published
3R3K
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BU of 3r3k by Molmil
Crystal structure of a parallel 6-helix coiled coil
Descriptor: 1,2-ETHANEDIOL, CChex-Phi22 helix, CHLORIDE ION, ...
Authors:Zaccai, N.R, Chi, B.H.C, Woolfson, D.N, Brady, R.L.
Deposit date:2011-03-16
Release date:2011-11-16
Last modified:2011-11-30
Method:X-RAY DIFFRACTION (2.2009 Å)
Cite:A de novo peptide hexamer with a mutable channel.
Nat.Chem.Biol., 7, 2011
4RWZ
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BU of 4rwz by Molmil
Crystal structure of the antibiotic-resistance methyltransferase Kmr
Descriptor: Putative rRNA methyltransferase
Authors:Savic, M.
Deposit date:2014-12-08
Release date:2015-03-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:30S Subunit-Dependent Activation of the Sorangium cellulosum So ce56 Aminoglycoside Resistance-Conferring 16S rRNA Methyltransferase Kmr.
Antimicrob.Agents Chemother., 59, 2015
4Q6R
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BU of 4q6r by Molmil
Crystal structure of human sphingosine-1-phosphate lyase in complex with inhibitor 6-[(2R)-4-(4-benzyl-7-chlorophthalazin-1-yl)-2-methylpiperazin-1-yl]pyridine-3-carbonitrile
Descriptor: 6-[(2R)-4-(4-benzyl-7-chlorophthalazin-1-yl)-2-methylpiperazin-1-yl]pyridine-3-carbonitrile, GLYCEROL, PHOSPHATE ION, ...
Authors:Srinivas, H.
Deposit date:2014-04-23
Release date:2014-05-21
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Orally Active 7-Substituted (4-Benzylphthalazin-1-yl)-2-methylpiperazin-1-yl]nicotinonitriles as Active-Site Inhibitors of Sphingosine 1-Phosphate Lyase for the Treatment of Multiple Sclerosis.
J.Med.Chem., 57, 2014
2ADM
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BU of 2adm by Molmil
ADENINE-N6-DNA-METHYLTRANSFERASE TAQI
Descriptor: ADENINE-N6-DNA-METHYLTRANSFERASE TAQI, S-ADENOSYLMETHIONINE
Authors:Schluckebier, G, Saenger, W.
Deposit date:1996-07-15
Release date:1997-01-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Differential binding of S-adenosylmethionine S-adenosylhomocysteine and Sinefungin to the adenine-specific DNA methyltransferase M.TaqI.
J.Mol.Biol., 265, 1997
4EV1
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BU of 4ev1 by Molmil
Anabaena Tic22 (protein transport)
Descriptor: 1,2-ETHANEDIOL, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Anabena Tic22, ...
Authors:Koenig, P, Schleiff, E, Sinning, I, Tews, I.
Deposit date:2012-04-25
Release date:2012-05-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Functional conservation of Tic22 in cyanobacterial outer membrane protein assembly and chloroplast translocation.
TO BE PUBLISHED
3R4A
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BU of 3r4a by Molmil
Crystal structure of the 4-helix coiled coil CC-tet
Descriptor: coiled coil helix CC-tet
Authors:Zaccai, N.R, Chi, B.H.C, Woolfson, D.N, Brady, R.L.
Deposit date:2011-03-17
Release date:2011-11-16
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.0701 Å)
Cite:A de novo peptide hexamer with a mutable channel.
Nat.Chem.Biol., 7, 2011
7JLZ
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BU of 7jlz by Molmil
Crystal structure of 30S ribosomal A1408 methyltransferase from an uncultured bacterium (UncKam)
Descriptor: 16S rRNA methylase, SULFATE ION
Authors:Nosrati, M, Conn, G.L.
Deposit date:2020-07-30
Release date:2021-08-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Roles of conserved tryptophans in substrate recognition and catalysis by the aminoglycoside-resistance 16S rRNA (m1A1408) rRNA methyltransferases
To be published
3R48
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BU of 3r48 by Molmil
Crystal structure of a hetero-hexamer coiled coil
Descriptor: GLYCEROL, coiled coil helix W22-L24H, coiled coil helix Y15-L24D
Authors:Zaccai, N.R, Chi, B.H.C, Woolfson, D.N, Brady, R.L.
Deposit date:2011-03-17
Release date:2011-11-16
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.0011 Å)
Cite:A de novo peptide hexamer with a mutable channel.
Nat.Chem.Biol., 7, 2011
3R4H
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BU of 3r4h by Molmil
Crystal structure of the 4-helix coiled coil CC-Tet-phi22
Descriptor: coiled coil helix CC-Tet-phi22
Authors:Zaccai, N.R, Chi, B.H.C, Woolfson, D.N, Brady, R.L.
Deposit date:2011-03-17
Release date:2011-11-16
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (2.7003 Å)
Cite:A de novo peptide hexamer with a mutable channel.
Nat.Chem.Biol., 7, 2011
4RX1
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BU of 4rx1 by Molmil
Crystal Structure of antibiotic-resistance methyltransferase Kmr
Descriptor: GLYCEROL, IODIDE ION, Putative rRNA methyltransferase
Authors:Savic, M.
Deposit date:2014-12-08
Release date:2015-03-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.472 Å)
Cite:30S Subunit-Dependent Activation of the Sorangium cellulosum So ce56 Aminoglycoside Resistance-Conferring 16S rRNA Methyltransferase Kmr.
Antimicrob.Agents Chemother., 59, 2015
3R47
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BU of 3r47 by Molmil
Crystal structure of a 6-helix coiled coil CC-hex-H24
Descriptor: BROMIDE ION, coiled coil helix L24H
Authors:Zaccai, N.R, Chi, B.H.C, Woolfson, D.N, Brady, R.L.
Deposit date:2011-03-17
Release date:2011-11-16
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.5002 Å)
Cite:A de novo peptide hexamer with a mutable channel.
Nat.Chem.Biol., 7, 2011
2H61
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BU of 2h61 by Molmil
X-ray structure of human Ca2+-loaded S100B
Descriptor: CALCIUM ION, Protein S100-B, TETRAETHYLENE GLYCOL
Authors:Ostendorp, T, Heizmann, C.W, Kroneck, P.M.H, Fritz, G.
Deposit date:2006-05-30
Release date:2007-06-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and functional insights into RAGE activation by multimeric S100B.
Embo J., 26, 2007
2XZG
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BU of 2xzg by Molmil
Clathrin Terminal Domain Complexed with Pitstop 1
Descriptor: 2-(4-AMINOBENZYL)-1,3-DIOXO-2,3-DIHYDRO-1H-BENZO[DE]ISOQUINOLINE-5-SULFONATE, ACETATE ION, CLATHRIN HEAVY CHAIN 1, ...
Authors:Bulut, H, Von Kleist, L, Saenger, W, Haucke, V.
Deposit date:2010-11-25
Release date:2011-08-17
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Role of the Clathrin Terminal Domain in Regulating Coated Pit Dynamics Revealed by Small Molecule Inhibition.
Cell(Cambridge,Mass.), 146, 2011
1G38
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BU of 1g38 by Molmil
ADENINE-SPECIFIC METHYLTRANSFERASE M. TAQ I/DNA COMPLEX
Descriptor: 5'-D(*GP*AP*CP*AP*TP*CP*GP*(6MA)P*AP*C)-3', 5'-D(*GP*TP*TP*CP*GP*AP*TP*GP*TP*C)-3', 5'-DEOXY-5'-[2-(AMINO)ETHYLTHIO]ADENOSINE, ...
Authors:Goedecke, K, Pignot, M, Goody, R.S, Scheidig, A.J, Weinhold, E.
Deposit date:2000-10-23
Release date:2001-03-05
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the N6-adenine DNA methyltransferase M.TaqI in complex with DNA and a cofactor analog.
Nat.Struct.Biol., 8, 2001
2IZA
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BU of 2iza by Molmil
APOSTREPTAVIDIN PH 2.00 I4122 STRUCTURE
Descriptor: FORMIC ACID, STREPTAVIDIN
Authors:Katz, B.A.
Deposit date:1997-08-13
Release date:1998-09-16
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:Binding of biotin to streptavidin stabilizes intersubunit salt bridges between Asp61 and His87 at low pH.
J.Mol.Biol., 274, 1997
2IZE
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BU of 2ize by Molmil
APOSTREPTAVIDIN PH 3.08 I222 COMPLEX
Descriptor: AMMONIUM ION, CHLORIDE ION, FORMIC ACID, ...
Authors:Katz, B.A.
Deposit date:1997-08-13
Release date:1998-09-16
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Binding of biotin to streptavidin stabilizes intersubunit salt bridges between Asp61 and His87 at low pH.
J.Mol.Biol., 274, 1997
2IZJ
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BU of 2izj by Molmil
STREPTAVIDIN-BIOTIN PH 3.50 I4122 STRUCTURE
Descriptor: BIOTIN, STREPTAVIDIN
Authors:Katz, B.A.
Deposit date:1997-08-13
Release date:1998-09-16
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Binding of biotin to streptavidin stabilizes intersubunit salt bridges between Asp61 and His87 at low pH.
J.Mol.Biol., 274, 1997
2IZD
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BU of 2izd by Molmil
APOSTREPTAVIDIN pH 3.0 I222 COMPLEX
Descriptor: AMMONIUM ION, CHLORIDE ION, IODIDE ION, ...
Authors:Katz, B.A.
Deposit date:1997-08-13
Release date:1998-09-23
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Binding of biotin to streptavidin stabilizes intersubunit salt bridges between Asp61 and His87 at low pH.
J.Mol.Biol., 274, 1997
2IZB
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BU of 2izb by Molmil
APOSTREPTAVIDIN PH 3.12 I4122 STRUCTURE
Descriptor: FORMIC ACID, STREPTAVIDIN, SULFATE ION
Authors:Katz, B.A.
Deposit date:1997-08-13
Release date:1998-09-16
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Binding of biotin to streptavidin stabilizes intersubunit salt bridges between Asp61 and His87 at low pH.
J.Mol.Biol., 274, 1997
2IZL
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BU of 2izl by Molmil
STREPTAVIDIN-2-IMINOBIOTIN PH 7.3 I222 COMPLEX
Descriptor: 2-IMINOBIOTIN, STREPTAVIDIN
Authors:Katz, B.A.
Deposit date:1997-08-13
Release date:1998-09-16
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Binding of biotin to streptavidin stabilizes intersubunit salt bridges between Asp61 and His87 at low pH.
J.Mol.Biol., 274, 1997
2IZK
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BU of 2izk by Molmil
STREPTAVIDIN-GLYCOLURIL PH 2.58 I4122 COMPLEX
Descriptor: ACETATE ION, GLYCOLURIL, STREPTAVIDIN, ...
Authors:Katz, B.A.
Deposit date:1997-08-13
Release date:1998-09-16
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Binding of biotin to streptavidin stabilizes intersubunit salt bridges between Asp61 and His87 at low pH.
J.Mol.Biol., 274, 1997
2IZI
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BU of 2izi by Molmil
STREPTAVIDIN-BIOTIN PH 2.53 I4122 STRUCTURE
Descriptor: BIOTIN, STREPTAVIDIN
Authors:Katz, B.A.
Deposit date:1997-08-13
Release date:1998-09-16
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Binding of biotin to streptavidin stabilizes intersubunit salt bridges between Asp61 and His87 at low pH.
J.Mol.Biol., 274, 1997

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