7X7J
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![BU of 7x7j by Molmil](/molmil-images/mine/7x7j) | Ancestral L-Lys oxidase (AncLLysO-2) L-Lys binding form | Descriptor: | FAD dependent enzyme, FLAVIN-ADENINE DINUCLEOTIDE, LYSINE | Authors: | Motoyama, T, Ishida, C, Hasebe, F, Ito, S, Nakano, S. | Deposit date: | 2022-03-09 | Release date: | 2023-01-18 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Reaction Mechanism of Ancestral l-Lys alpha-Oxidase from Caulobacter Species Studied by Biochemical, Structural, and Computational Analysis Acs Omega, 7, 2022
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1ROM
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2GW9
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![BU of 2gw9 by Molmil](/molmil-images/mine/2gw9) | High-resolution solution structure of the mouse defensin Cryptdin4 | Descriptor: | Defensin-related cryptdin 4 | Authors: | Rosengren, K.J, Craik, D.J, Vogel, H.J, Daly, N.L, Ouellette, A.J. | Deposit date: | 2006-05-04 | Release date: | 2006-07-25 | Last modified: | 2022-03-09 | Method: | SOLUTION NMR | Cite: | Structural and functional characterization of the conserved salt bridge in mammalian paneth cell alpha-defensins: solution structures of mouse CRYPTDIN-4 and (E15D)-CRYPTDIN-4. J.Biol.Chem., 281, 2006
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2GWP
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![BU of 2gwp by Molmil](/molmil-images/mine/2gwp) | High-resolution solution structure of the salt-bridge defficient mouse defensin (E15D)-Cryptdin4 | Descriptor: | Defensin-related cryptdin 4 | Authors: | Rosengren, K.J, Craik, D.J, Vogel, H.J, Daly, N.L, Ouellette, A.J. | Deposit date: | 2006-05-05 | Release date: | 2006-07-25 | Last modified: | 2021-10-20 | Method: | SOLUTION NMR | Cite: | Structural and functional characterization of the conserved salt bridge in mammalian paneth cell alpha-defensins: solution structures of mouse CRYPTDIN-4 and (E15D)-CRYPTDIN-4. J.Biol.Chem., 281, 2006
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2H8A
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2KPH
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![BU of 2kph by Molmil](/molmil-images/mine/2kph) | NMR Structure of AtraPBP1 at pH 4.5 | Descriptor: | Pheromone binding protein | Authors: | Ames, J. | Deposit date: | 2009-10-15 | Release date: | 2010-02-02 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | NMR Structure of Navel Orangeworm Moth Pheromone-Binding Protein (AtraPBP1): Implications for pH-Sensitive Pheromone Detection . Biochemistry, 49, 2010
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7XTX
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![BU of 7xtx by Molmil](/molmil-images/mine/7xtx) | High resolution crystal structure of human macrophage migration inhibitory factor in complex with methotrexate | Descriptor: | 1,2-ETHANEDIOL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ... | Authors: | Sugishima, K, Noguchi, K, Yohda, M, Odaka, M, Matsumura, H. | Deposit date: | 2022-05-18 | Release date: | 2023-05-24 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.28 Å) | Cite: | Identification of methotrexate as an inhibitor of macrophage migration inhibitory factor by high-resolution crystal structure analysis To Be Published
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2KXE
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3WDQ
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![BU of 3wdq by Molmil](/molmil-images/mine/3wdq) | Crystal structure of beta-mannanase from a symbiotic protist of the termite Reticulitermes speratus | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-mannanase, MAGNESIUM ION, ... | Authors: | Tsukagoshi, H, Ishida, T, Touhara, K.K, Igarashi, K, Samejima, M, Fushinobu, S, Kitamoto, K, Arioka, M. | Deposit date: | 2013-06-20 | Release date: | 2014-03-05 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Structural and Biochemical Analyses of Glycoside Hydrolase Family 26 beta-Mannanase from a Symbiotic Protist of the Termite Reticulitermes speratus J.Biol.Chem., 289, 2014
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2L22
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![BU of 2l22 by Molmil](/molmil-images/mine/2l22) | Mupirocin didomain ACP | Descriptor: | Mupirocin didomain Acyl Carrier Protein | Authors: | Dong, X, Williams, C, Crump, M.P, Wattana-amorn, P. | Deposit date: | 2010-08-10 | Release date: | 2012-02-15 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | A conserved motif flags acyl carrier proteins for beta-branching in polyketide synthesis. Nat.Chem.Biol., 9, 2013
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7VBM
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![BU of 7vbm by Molmil](/molmil-images/mine/7vbm) | The mouse nucleosome structure containing H3mm18 aided by PL2-6 scFv | Descriptor: | DNA (126-MER), Histone H2A type 1-B, Histone H2B type 3-A, ... | Authors: | Hirai, S, Takizawa, Y, Kujirai, T, Kurumizaka, H. | Deposit date: | 2021-08-31 | Release date: | 2022-01-19 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Unusual nucleosome formation and transcriptome influence by the histone H3mm18 variant. Nucleic Acids Res., 50, 2022
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1UCG
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![BU of 1ucg by Molmil](/molmil-images/mine/1ucg) | Crystal structure of Ribonuclease MC1 N71T mutant | Descriptor: | MANGANESE (II) ION, Ribonuclease MC | Authors: | Suzuki, A, Numata, T, Yao, M, Tanaka, I, Kimura, M. | Deposit date: | 2003-04-14 | Release date: | 2003-04-29 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Crystal structures of the ribonuclease MC1 mutants N71T and N71S in complex with 5'-GMP: structural basis for alterations in substrate specificity Biochemistry, 42, 2003
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1UGO
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![BU of 1ugo by Molmil](/molmil-images/mine/1ugo) | Solution structure of the first Murine BAG domain of Bcl2-associated athanogene 5 | Descriptor: | Bcl2-associated athanogene 5 | Authors: | Endoh, H, Hayashi, F, Seimiya, K, Shirouzu, M, Terada, T, Kigawa, T, Inoue, M, Yabuki, T, Aoki, M, Seki, E, Matsuda, T, Hirota, H, Yoshida, M, Tanaka, A, Osanai, T, Arakawa, T, Carninci, P, Kawai, J, Hayashizaki, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2003-06-17 | Release date: | 2004-08-03 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | The C-terminal BAG domain of BAG5 induces conformational changes of the Hsp70 nucleotide-binding domain for ADP-ATP exchange Structure, 18, 2010
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2Z8G
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![BU of 2z8g by Molmil](/molmil-images/mine/2z8g) | Aspergillus niger ATCC9642 isopullulanase complexed with isopanose | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Isopullulanase, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-6)-beta-D-glucopyranose | Authors: | Mizuno, M, Koide, A, Yamamura, A, Akeboshi, H, Yoshida, H, Kamitori, S, Sakano, Y, Nishikawa, A, Tonozuka, T. | Deposit date: | 2007-09-05 | Release date: | 2007-12-18 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal Structure of Aspergillus niger Isopullulanase, a Member of Glycoside Hydrolase Family 49 J.Mol.Biol., 376, 2008
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7EA4
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7EBY
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3W80
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3W7Y
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3WMT
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![BU of 3wmt by Molmil](/molmil-images/mine/3wmt) | Crystal structure of feruloyl esterase B from Aspergillus oryzae | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Probable feruloyl esterase B-1 | Authors: | Suzuki, K, Ishida, T, Igarashi, K, Koseki, T, Fushinobu, S. | Deposit date: | 2013-11-25 | Release date: | 2014-08-06 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal structure of a feruloyl esterase belonging to the tannase family: a disulfide bond near a catalytic triad. Proteins, 82, 2014
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3W7Z
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5XIF
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![BU of 5xif by Molmil](/molmil-images/mine/5xif) | Crystal Structure of Prolyl-tRNA Synthetase (PRS) from Toxoplasma gondii | Descriptor: | CHLORIDE ION, Prolyl-tRNA synthetase (ProRS) | Authors: | Jain, V, Manickam, Y, Sharma, A. | Deposit date: | 2017-04-26 | Release date: | 2018-03-07 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | Targeting Prolyl-tRNA Synthetase to Accelerate Drug Discovery against Malaria, Leishmaniasis, Toxoplasmosis, Cryptosporidiosis, and Coccidiosis Structure, 25, 2017
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5XIQ
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![BU of 5xiq by Molmil](/molmil-images/mine/5xiq) | Crystal Structure of Toxoplasma gondii Prolyl-tRNA Synthetase (TgPRS) in complex with Halofuginone | Descriptor: | 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Jain, V, Manickam, Y, Sharma, A. | Deposit date: | 2017-04-26 | Release date: | 2018-03-07 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Targeting Prolyl-tRNA Synthetase to Accelerate Drug Discovery against Malaria, Leishmaniasis, Toxoplasmosis, Cryptosporidiosis, and Coccidiosis Structure, 25, 2017
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3VHA
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![BU of 3vha by Molmil](/molmil-images/mine/3vha) | Hsp90 alpha N-terminal domain in complex with a macrocyclic inhibitor | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 22-methyl-13,18-dioxa-7-thia-3,5-diazatetracyclo[17.3.1.1~2,6~.1~8,12~]pentacosa-1(23),2(25),3,5,8(24),9,11,19,21-nonaen-4-amine, Heat shock protein HSP 90-alpha | Authors: | Fukami, T.A, Ono, N. | Deposit date: | 2011-08-24 | Release date: | 2012-07-18 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.39 Å) | Cite: | Design and synthesis of novel macrocyclic 2-amino-6-arylpyrimidine Hsp90 inhibitors Bioorg.Med.Chem.Lett., 22, 2012
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5XII
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![BU of 5xii by Molmil](/molmil-images/mine/5xii) | Crystal Structure of Toxoplasma gondii Prolyl-tRNA Synthetase (TgPRS) in complex with inhibitor 6 | Descriptor: | 1,2-ETHANEDIOL, 6-chloranyl-7-fluoranyl-3-[3-[(2R)-3-oxidanylidenepiperidin-2-yl]propyl]quinazolin-4-one, CHLORIDE ION, ... | Authors: | Jain, V, Manickam, Y, Sharma, A. | Deposit date: | 2017-04-26 | Release date: | 2018-03-07 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | Targeting Prolyl-tRNA Synthetase to Accelerate Drug Discovery against Malaria, Leishmaniasis, Toxoplasmosis, Cryptosporidiosis, and Coccidiosis Structure, 25, 2017
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3VHC
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![BU of 3vhc by Molmil](/molmil-images/mine/3vhc) | Hsp90 alpha N-terminal domain in complex with a macrocyclic inhibitor | Descriptor: | 4-amino-20,22-dimethyl-13-oxa-7-thia-3,5,17-triazatetracyclo[17.3.1.1~2,6~.1~8,12~]pentacosa-1(23),2(25),3,5,8(24),9,11,19,21-nonaen-18-one, Heat shock protein HSP 90-alpha, MAGNESIUM ION | Authors: | Fukami, T.A, Ono, N. | Deposit date: | 2011-08-24 | Release date: | 2012-07-18 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.41 Å) | Cite: | Design and synthesis of novel macrocyclic 2-amino-6-arylpyrimidine Hsp90 inhibitors Bioorg.Med.Chem.Lett., 22, 2012
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