8KIH
| PhmA, a type I diterpene synthase without NST/DTE motif | Descriptor: | (2Z,6E,10E)-2-fluoro-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraen-1-yl trihydrogen diphosphate, MAGNESIUM ION, diterpene synthase, ... | Authors: | Zhang, B, Ge, H.M, Zhu, A, Zhang, Y. | Deposit date: | 2023-08-23 | Release date: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Biosynthesis of Platelet Activating Factor Antagonist Phomactins Revealing a New Class of Type I Diterpene Synthase To Be Published
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7WKP
| ICP1 Csy4 | Descriptor: | 3' stem loop crRNA, Csy4 | Authors: | Zhang, M, Peng, R. | Deposit date: | 2022-01-10 | Release date: | 2023-04-26 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Mechanistic insights into DNA binding and cleavage by a compact type I-F CRISPR-Cas system in bacteriophage. Proc.Natl.Acad.Sci.USA, 120, 2023
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7WKO
| ICP1 Csy1-2 complex | Descriptor: | Csy1, Csy2 | Authors: | Zhang, M, Peng, R. | Deposit date: | 2022-01-10 | Release date: | 2023-04-26 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Mechanistic insights into DNA binding and cleavage by a compact type I-F CRISPR-Cas system in bacteriophage. Proc.Natl.Acad.Sci.USA, 120, 2023
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7X6L
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7VEO
| Crystal structure of juvenile hormone acid methyltransferase silkworm JHAMT isoform3 complex with S-Adenosyl-L-homocysteine | Descriptor: | Methyltranfer_dom domain-containing protein, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Guo, P.C, Zhang, Y.S, Zhang, l, Xu, H.Y. | Deposit date: | 2021-09-09 | Release date: | 2022-09-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.53 Å) | Cite: | Structural characterization and functional analysis of juvenile hormone acid methyltransferase JHAMT3 from the silkworm, Bombyx mori. Insect Biochem.Mol.Biol., 151, 2022
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7WWV
| DNA bound-ICP1 Csy complex | Descriptor: | Csy1, Csy2, Csy3, ... | Authors: | Zhang, M, Peng, R. | Deposit date: | 2022-02-14 | Release date: | 2023-04-26 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Mechanistic insights into DNA binding and cleavage by a compact type I-F CRISPR-Cas system in bacteriophage. Proc.Natl.Acad.Sci.USA, 120, 2023
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7WWU
| ICP1 Csy complex | Descriptor: | Csy1, Csy2, Csy3, ... | Authors: | Zhang, M, Peng, R. | Deposit date: | 2022-02-14 | Release date: | 2023-04-26 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Mechanistic insights into DNA binding and cleavage by a compact type I-F CRISPR-Cas system in bacteriophage. Proc.Natl.Acad.Sci.USA, 120, 2023
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7V2S
| Crystal structure of juvenile hormone acid methyltransferase JHAMT isoform3 from silkworm | Descriptor: | Methyltranfer_dom domain-containing protein | Authors: | Guo, P.C, Zhang, Y.S, Zhang, l, Xu, H.Y. | Deposit date: | 2021-08-09 | Release date: | 2022-08-10 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.133 Å) | Cite: | Structural characterization and functional analysis of juvenile hormone acid methyltransferase JHAMT3 from the silkworm, Bombyx mori. Insect Biochem.Mol.Biol., 151, 2022
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8IRL
| Apo state of Arabidopsis AZG1 at pH 7.4 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Adenine/guanine permease AZG1 | Authors: | Xu, L, Guo, J. | Deposit date: | 2023-03-19 | Release date: | 2024-01-17 | Last modified: | 2024-02-07 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Structures and mechanisms of the Arabidopsis cytokinin transporter AZG1. Nat.Plants, 10, 2024
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8IRN
| 6-BAP bound state of Arabidopsis AZG1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Adenine/guanine permease AZG1, N-BENZYL-9H-PURIN-6-AMINE | Authors: | Xu, L, Guo, J. | Deposit date: | 2023-03-19 | Release date: | 2024-01-17 | Last modified: | 2024-02-07 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Structures and mechanisms of the Arabidopsis cytokinin transporter AZG1. Nat.Plants, 10, 2024
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8IRP
| kinetin bound state of Arabidopsis AZG1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Adenine/guanine permease AZG1, N-(FURAN-2-YLMETHYL)-7H-PURIN-6-AMINE | Authors: | Xu, L, Guo, J. | Deposit date: | 2023-03-19 | Release date: | 2024-01-17 | Last modified: | 2024-02-07 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structures and mechanisms of the Arabidopsis cytokinin transporter AZG1. Nat.Plants, 10, 2024
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8IRM
| Endogenous substrate adenine bound state of Arabidopsis AZG1 at pH 5.5 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENINE, Adenine/guanine permease AZG1 | Authors: | Xu, L, Guo, J. | Deposit date: | 2023-03-19 | Release date: | 2024-01-17 | Last modified: | 2024-02-07 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Structures and mechanisms of the Arabidopsis cytokinin transporter AZG1. Nat.Plants, 10, 2024
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8IRO
| trans-Zeatin bound state of Arabidopsis AZG1 at pH7.4 | Descriptor: | (2E)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Adenine/guanine permease AZG1 | Authors: | Xu, L, Guo, J. | Deposit date: | 2023-03-19 | Release date: | 2024-01-17 | Last modified: | 2024-02-07 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Structures and mechanisms of the Arabidopsis cytokinin transporter AZG1. Nat.Plants, 10, 2024
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7X6O
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7VP9
| Crystal structure of human ClpP in complex with ZG111 | Descriptor: | (6S,9aS)-N-[(4-bromophenyl)methyl]-6-[(2S)-butan-2-yl]-8-(naphthalen-1-ylmethyl)-4,7-bis(oxidanylidene)-3,6,9,9a-tetrahydro-2H-pyrazino[1,2-a]pyrimidine-1-carboxamide, ATP-dependent Clp protease proteolytic subunit, mitochondrial, ... | Authors: | Wang, P.Y, Gan, J.H, Yang, C.-G. | Deposit date: | 2021-10-15 | Release date: | 2022-06-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.552 Å) | Cite: | Aberrant human ClpP activation disturbs mitochondrial proteome homeostasis to suppress pancreatic ductal adenocarcinoma. Cell Chem Biol, 29, 2022
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7EPZ
| Overall structure of Erastin-bound xCT-4F2hc complex | Descriptor: | 1,2-DISTEAROYL-SN-GLYCERO-3-PHOSPHATE, 2-[(1S)-1-[4-[2-(4-chloranylphenoxy)ethanoyl]piperazin-1-yl]ethyl]-3-(2-ethoxyphenyl)quinazolin-4-one, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Yan, R.H, Li, Y.N, Zhang, Y.Y, Chi, X.M, Zhou, Q. | Deposit date: | 2021-04-28 | Release date: | 2022-04-06 | Last modified: | 2022-07-13 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | The structure of erastin-bound xCT-4F2hc complex reveals molecular mechanisms underlying erastin-induced ferroptosis. Cell Res., 32, 2022
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7YFY
| Cryo-EM structure of the Mili-piRNA- target ternary complex | Descriptor: | MAGNESIUM ION, Piwi-like protein 2, RNA (5'-R(P*CP*CP*AP*UP*GP*UP*UP*GP*AP*UP*GP*GP*UP*AP*A)-3'), ... | Authors: | Li, Z.Q, Liu, H.B, Wu, J.P, Shen, E.Z. | Deposit date: | 2022-07-09 | Release date: | 2024-01-24 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Mammalian PIWI-piRNA-target complexes reveal features for broad and efficient target silencing. Nat.Struct.Mol.Biol., 2024
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7XXJ
| Echo 18 incubated with FcRn at pH5.5 | Descriptor: | PALMITIC ACID, VP1, VP2, ... | Authors: | Liu, C.C, Qu, X. | Deposit date: | 2022-05-30 | Release date: | 2022-06-29 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.33 Å) | Cite: | Human FcRn Is a Two-in-One Attachment-Uncoating Receptor for Echovirus 18. Mbio, 13, 2022
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7XXA
| Complex of Echo 18 and FcRn at pH7.4 | Descriptor: | IgG receptor FcRn large subunit p51, VP1, VP2, ... | Authors: | Liu, C.C, Qu, X. | Deposit date: | 2022-05-29 | Release date: | 2022-06-29 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.09 Å) | Cite: | Human FcRn Is a Two-in-One Attachment-Uncoating Receptor for Echovirus 18. Mbio, 13, 2022
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7WKS
| Apo state of AtPIN3 | Descriptor: | Auxin efflux carrier component 3 | Authors: | Su, N. | Deposit date: | 2022-01-11 | Release date: | 2022-08-10 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structures and mechanisms of the Arabidopsis auxin transporter PIN3. Nature, 609, 2022
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7WKW
| NPA bound state of AtPIN3 | Descriptor: | 2-(naphthalen-1-ylcarbamoyl)benzoic acid, Auxin efflux carrier component 3 | Authors: | Su, N. | Deposit date: | 2022-01-11 | Release date: | 2022-08-10 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (2.62 Å) | Cite: | Structures and mechanisms of the Arabidopsis auxin transporter PIN3. Nature, 609, 2022
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7XXG
| Echo 18 at pH5.5 | Descriptor: | PALMITIC ACID, VP1, VP2, ... | Authors: | Liu, C.C, Qu, X. | Deposit date: | 2022-05-30 | Release date: | 2022-06-29 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.37 Å) | Cite: | Human FcRn Is a Two-in-One Attachment-Uncoating Receptor for Echovirus 18. Mbio, 13, 2022
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8K4F
| DHODH in complex with compound A0 | Descriptor: | 5-cyclopropyl-2-[1-[(2-fluorophenyl)methyl]pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-4-amine, 6-[bis(oxidanyl)methyl]-5~{H}-pyrimidine-2,4-dione, ACETATE ION, ... | Authors: | Jian, L, Sun, Q. | Deposit date: | 2023-07-18 | Release date: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | Discovery and Optimization of Novel h DHODH Inhibitors for the Treatment of Inflammatory Bowel Disease. J.Med.Chem., 66, 2023
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7XXB
| IAA bound state of AtPIN3 | Descriptor: | 1H-INDOL-3-YLACETIC ACID, Auxin efflux carrier component 3 | Authors: | Su, N. | Deposit date: | 2022-05-29 | Release date: | 2022-08-10 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.93 Å) | Cite: | Structures and mechanisms of the Arabidopsis auxin transporter PIN3. Nature, 609, 2022
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7Y75
| SIT1-ACE2-BA.2 RBD | Descriptor: | 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Shen, Y.P, Li, Y.N, Zhang, Y.Y, Yan, R.H. | Deposit date: | 2022-06-21 | Release date: | 2022-11-30 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structures of ACE2-SIT1 recognized by Omicron variants of SARS-CoV-2. Cell Discov, 8, 2022
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