7XCR
 
 | | Cryo-EM structure of Dot1L and H2BK34ub-H3K79Nle nucleosome 1:1 complex | | Descriptor: | DNA (146-MER), Histone H2A, Histone H2B type 1-K, ... | | Authors: | Ai, H.S, Liu, A.J, Lou, Z.Y, Liu, L. | | Deposit date: | 2022-03-25 | | Release date: | 2022-04-20 | | Last modified: | 2022-09-07 | | Method: | ELECTRON MICROSCOPY (2.57 Å) | | Cite: | H2B Lys34 Ubiquitination Induces Nucleosome Distortion to Stimulate Dot1L Activity.
Nat.Chem.Biol., 18, 2022
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7XCT
 | | Cryo-EM structure of Dot1L and H2BK34ub-H3K79Nle nucleosome 2:1 complex | | Descriptor: | DNA (145-MER), Histone H2A, Histone H2B type 1-K, ... | | Authors: | Ai, H.S, Liu, A.J, Lou, Z.Y, Liu, L. | | Deposit date: | 2022-03-25 | | Release date: | 2022-04-20 | | Last modified: | 2022-09-07 | | Method: | ELECTRON MICROSCOPY (2.72 Å) | | Cite: | H2B Lys34 Ubiquitination Induces Nucleosome Distortion to Stimulate Dot1L Activity.
Nat.Chem.Biol., 18, 2022
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7XD0
 | | cryo-EM structure of H2BK34ub nucleosome | | Descriptor: | DNA (146-MER), Histone H2A, Histone H2B type 1-K, ... | | Authors: | Ai, H.S, Liu, A.J, Lou, Z.Y, Liu, L. | | Deposit date: | 2022-03-26 | | Release date: | 2022-04-20 | | Last modified: | 2024-06-26 | | Method: | ELECTRON MICROSCOPY (3.48 Å) | | Cite: | H2B Lys34 Ubiquitination Induces Nucleosome Distortion to Stimulate Dot1L Activity.
Nat.Chem.Biol., 18, 2022
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7XD1
 | | cryo-EM structure of unmodified nucleosome | | Descriptor: | DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ... | | Authors: | Ai, H.S, Liu, A.J, Lou, Z.Y, Liu, L. | | Deposit date: | 2022-03-26 | | Release date: | 2022-04-20 | | Last modified: | 2024-06-26 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | H2B Lys34 Ubiquitination Induces Nucleosome Distortion to Stimulate Dot1L Activity.
Nat.Chem.Biol., 18, 2022
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8IQ6
 | | Cryo-EM structure of Latanoprost-bound prostaglandin-F2-alpha receptor-miniGq-Nb35 complex | | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | | Authors: | Lv, X, Gao, K, Nie, J, Zhang, X, Zhang, S, Ren, Y, Li, Q, Huang, J, Liu, L, Zhang, X, Sun, X, Zhang, W, Liu, X. | | Deposit date: | 2023-03-15 | | Release date: | 2024-01-31 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structures of human prostaglandin F 2 alpha receptor reveal the mechanism of ligand and G protein selectivity.
Nat Commun, 14, 2023
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8IQ4
 | | Cryo-EM structure of Carboprost-bound prostaglandin-F2-alpha receptor-miniGq-Nb35 complex | | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | | Authors: | Lv, X, Gao, K, Nie, J, Zhang, X, Zhang, S, Ren, Y, Li, Q, Huang, J, Liu, L, Zhang, X, Sun, X, Zhang, W, Liu, X. | | Deposit date: | 2023-03-15 | | Release date: | 2024-01-31 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Structures of human prostaglandin F 2 alpha receptor reveal the mechanism of ligand and G protein selectivity.
Nat Commun, 14, 2023
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5FW5
 | | Crystal structure of human G3BP1 in complex with Semliki Forest Virus nsP3-25 comprising two FGDF motives | | Descriptor: | ACETATE ION, GLYCEROL, NON-STRUCTURAL PROTEIN 3, ... | | Authors: | Schulte, T, Liu, L, Panas, M.D, Thaa, B, Goette, B, Achour, A, McInerney, G.M. | | Deposit date: | 2016-02-12 | | Release date: | 2016-07-20 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.92 Å) | | Cite: | Combined structural, biochemical and cellular evidence demonstrates that both FGDF motifs in alphavirus nsP3 are required for efficient replication.
Open Biol, 6, 2016
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5H3E
 | | Crystal structure of mouse isocitrate dehydrogenases 2 K256Q mutant complexed with isocitrate | | Descriptor: | ISOCITRIC ACID, Isocitrate dehydrogenase [NADP], mitochondrial, ... | | Authors: | Xu, Y, Liu, L, Miyakawa, T, Nakamura, A, Tanokura, M. | | Deposit date: | 2016-10-23 | | Release date: | 2017-08-30 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.21 Å) | | Cite: | Studies on the regulatory mechanism of isocitrate dehydrogenase 2 using acetylation mimics
Sci Rep, 7, 2017
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5H3F
 | | Crystal structure of mouse isocitrate dehydrogenases 2 complexed with isocitrate | | Descriptor: | ISOCITRIC ACID, Isocitrate dehydrogenase [NADP], mitochondrial, ... | | Authors: | Xu, Y, Liu, L, Miyakawa, T, Nakamura, A, Tanokura, M. | | Deposit date: | 2016-10-23 | | Release date: | 2017-08-30 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3.29 Å) | | Cite: | Studies on the regulatory mechanism of isocitrate dehydrogenase 2 using acetylation mimics
Sci Rep, 7, 2017
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8WG5
 | | Cryo-EM structure of USP16 bound to H2AK119Ub nucleosome | | Descriptor: | DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ... | | Authors: | Ai, H.S, He, Z.Z, Deng, Z.H, Liu, L. | | Deposit date: | 2023-09-20 | | Release date: | 2023-12-27 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (3.05 Å) | | Cite: | Structural and mechanistic basis for nucleosomal H2AK119 deubiquitination by single-subunit deubiquitinase USP16.
Nat.Struct.Mol.Biol., 2024
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5HGZ
 | | Crystal structure of human Naa60 in complex with acetyl-CoA | | Descriptor: | ACETYL COENZYME *A, MALONIC ACID, N-alpha-acetyltransferase 60 | | Authors: | Chen, J.Y, Liu, L, Yun, C.H. | | Deposit date: | 2016-01-09 | | Release date: | 2016-09-14 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.383 Å) | | Cite: | Structure and function of human Naa60 (NatF), a Golgi-localized bi-functional acetyltransferase
Sci Rep, 6, 2016
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5WLL
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5FFE
 | | CopM in the Ag-bound form (by soaking) | | Descriptor: | CopM, SILVER ION | | Authors: | Zhao, S, Wang, X, Liu, L. | | Deposit date: | 2015-12-18 | | Release date: | 2016-09-07 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.096 Å) | | Cite: | Structural basis for copper/silver binding by the Synechocystis metallochaperone CopM.
Acta Crystallogr D Struct Biol, 72, 2016
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5FFD
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5HH0
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5FFB
 | | CopM in the apo form | | Descriptor: | CopM | | Authors: | Zhao, S, Wang, X, Liu, L. | | Deposit date: | 2015-12-18 | | Release date: | 2016-09-07 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.702 Å) | | Cite: | Structural basis for copper/silver binding by the Synechocystis metallochaperone CopM.
Acta Crystallogr D Struct Biol, 72, 2016
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5HH1
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5WLJ
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5WLM
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3PS5
 | | Crystal structure of the full-length Human Protein Tyrosine Phosphatase SHP-1 | | Descriptor: | SULFATE ION, Tyrosine-protein phosphatase non-receptor type 6 | | Authors: | Wang, W, Liu, L, Song, X, Mo, Y, Komma, C, Bellamy, H.D, Zhao, Z.J, Zhou, G.W. | | Deposit date: | 2010-11-30 | | Release date: | 2011-04-20 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Crystal structure of human protein tyrosine phosphatase SHP-1 in the open conformation.
J.Cell.Biochem., 112, 2011
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5WZE
 | | The structure of Pseudomonas aeruginosa aminopeptidase PepP | | Descriptor: | 1,2-ETHANEDIOL, ALANINE, Aminopeptidase P, ... | | Authors: | Bao, R, Peng, C.T, Liu, L, He, L.H, Li, C.C, Li, T, Shen, Y.L, Zhu, Y.B, Song, Y.J. | | Deposit date: | 2017-01-17 | | Release date: | 2018-01-17 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.783 Å) | | Cite: | Structure-Function Relationship of Aminopeptidase P from Pseudomonas aeruginosa.
Front Microbiol, 8, 2017
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5FFC
 | | CopM in the Cu(II)-bound form | | Descriptor: | COPPER (II) ION, CopM, SULFATE ION | | Authors: | Zhao, S, Wang, X, Liu, L. | | Deposit date: | 2015-12-18 | | Release date: | 2016-09-07 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.007 Å) | | Cite: | Structural basis for copper/silver binding by the Synechocystis metallochaperone CopM.
Acta Crystallogr D Struct Biol, 72, 2016
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5VBT
 | | Crystal structure of a highly specific and potent USP7 ubiquitin variant inhibitor | | Descriptor: | UBH04 | | Authors: | DONG, A, DONG, X, LIU, L, GUO, Y, LI, Y, ZHANG, W, WALKER, J.R, SIDHU, S, Bountra, C, Arrowsmith, C.H, Edwards, A.M, TONG, Y, Structural Genomics Consortium (SGC) | | Deposit date: | 2017-03-30 | | Release date: | 2017-06-07 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.51 Å) | | Cite: | Crystal structure of a highly specific and potent USP7 ubiquitin variant inhibitor
to be published
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5GND
 | | Structure of Deg protease HhoA from Synechocystis sp. PCC 6803 | | Descriptor: | Putative serine protease HhoA, SODIUM ION, UNK-UNK-UNK-UNK-TRP, ... | | Authors: | Dong, W, Wang, J, Liu, L. | | Deposit date: | 2016-07-20 | | Release date: | 2016-09-21 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of the zinc-bound HhoA protease from Synechocystis sp. PCC 6803
Febs Lett., 590, 2016
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5WLK
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