6J1V
| The structure of HLA-A*3003/RT313 | Descriptor: | Beta-2-microglobulin, HLA-A*3003, RT313 | Authors: | Zhu, S.Y, Liu, K.F, Chai, Y, Ding, C.M, Lv, J.X, Gao, G.F, Lou, Y.L, Liu, W.J. | Deposit date: | 2018-12-29 | Release date: | 2019-09-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Divergent Peptide Presentations of HLA-A*30 Alleles Revealed by Structures With Pathogen Peptides. Front Immunol, 10, 2019
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6J2J
| Crystal structure of bat (Pteropus Alecto) MHC class I Ptal-N*01:01 in complex with MERS-CoV-derived peptide MERS-CoV-S3 | Descriptor: | Beta-2-microglobulin, MERS-CoV-S3, Ptal-N*01:01 | Authors: | Lu, D, Liu, K.F, Yue, C, Lu, Q, Cheng, H, Chai, Y, Qi, J.X, Gao, G.F, Liu, W.J. | Deposit date: | 2019-01-01 | Release date: | 2019-09-18 | Last modified: | 2019-12-04 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Peptide presentation by bat MHC class I provides new insight into the antiviral immunity of bats. Plos Biol., 17, 2019
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7X1M
| The complex structure of Omicron BA.1 RBD with BD604, S309,and S304 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, BD-604 Fab heavy chain, BD-604 Fab light chain, ... | Authors: | Huang, M, Xie, Y.F, Qi, J.X. | Deposit date: | 2022-02-24 | Release date: | 2022-07-06 | Last modified: | 2023-07-19 | Method: | ELECTRON MICROSCOPY (2.74 Å) | Cite: | Atlas of currently available human neutralizing antibodies against SARS-CoV-2 and escape by Omicron sub-variants BA.1/BA.1.1/BA.2/BA.3. Immunity, 55, 2022
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3G51
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8KA8
| Cryo-EM structure of SARS-CoV-2 Delta RBD in complex with golden hamster ACE2 (local refinement) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, ... | Authors: | Niu, S, Zhao, Z.N, Chai, Y, Gao, G.F. | Deposit date: | 2023-08-02 | Release date: | 2024-01-31 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (2.96 Å) | Cite: | Structural basis and analysis of hamster ACE2 binding to different SARS-CoV-2 spike RBDs. J.Virol., 98, 2024
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8KC2
| Cryo-EM structure of SARS-CoV-2 BA.3 RBD in complex with golden hamster ACE2 (local refinement) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, ... | Authors: | Niu, S, Zhao, Z.N, Chai, Y, Gao, G.F. | Deposit date: | 2023-08-05 | Release date: | 2024-01-31 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Structural basis and analysis of hamster ACE2 binding to different SARS-CoV-2 spike RBDs. J.Virol., 98, 2024
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6K7T
| Crystal structure of bat (Pteropus Alecto) MHC class I Ptal-N*01:01 in complex with Hendra virus-derived peptide HeV1--human beta-2 microglobulin | Descriptor: | Beta-2-microglobulin, HeV1, MHC class I antigen | Authors: | Lu, D, Liu, K.F, Zhang, D, Yue, C, Lu, Q, Cheng, H, Chai, Y, Qi, J.X, Gao, F.G, Liu, W.J. | Deposit date: | 2019-06-08 | Release date: | 2019-11-06 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Peptide presentation by bat MHC class I provides new insight into the antiviral immunity of bats. Plos Biol., 17, 2019
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6K7U
| Crystal structure of beta-2 microglobulin (beta2m) of Bat (Pteropus Alecto) | Descriptor: | Bat beta-2-microglobulin | Authors: | Lu, D, Liu, K.F, Zhang, D, Yue, C, Lu, Q, Cheng, H, Chai, Y, Qi, J.X, Gao, F.G, Liu, W.J. | Deposit date: | 2019-06-08 | Release date: | 2019-09-18 | Last modified: | 2019-12-04 | Method: | X-RAY DIFFRACTION (1.601 Å) | Cite: | Peptide presentation by bat MHC class I provides new insight into the antiviral immunity of bats. Plos Biol., 17, 2019
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6OGJ
| MeCP2 MBD in complex with DNA | Descriptor: | DNA (5'-D(*CP*GP*GP*AP*GP*TP*GP*TP*AP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*TP*AP*CP*AP*CP*TP*CP*CP*G)-3'), Methyl-CpG-binding protein 2, ... | Authors: | Lei, M, Tempel, W, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | Deposit date: | 2019-04-02 | Release date: | 2019-05-01 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Plasticity at the DNA recognition site of the MeCP2 mCG-binding domain. Biochim Biophys Acta Gene Regul Mech, 1862, 2019
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8HRX
| Cryo-EM structure of human NTCP-myr-preS1-YN9048Fab complex | Descriptor: | Fab heavy chain from antibody IgG clone number YN9048, Fab light chain from antibody IgG clone number YN9048, PreS1 protein (Fragment), ... | Authors: | Asami, J, Shimizu, T, Ohto, U. | Deposit date: | 2022-12-16 | Release date: | 2024-01-17 | Last modified: | 2024-04-03 | Method: | ELECTRON MICROSCOPY (2.89 Å) | Cite: | Structural basis of hepatitis B virus receptor binding. Nat.Struct.Mol.Biol., 31, 2024
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8J7W
| Cryo-EM structure of hZnT7-Fab complex in zinc state 2, determined in heterogeneous conformations- one subunit in an inward-facing zinc-bound and the other in an outward-facing zinc-bound conformation | Descriptor: | Heavy chain of YN7114-08 Fab, Light chain of YN7114-08 Fab, ZINC ION, ... | Authors: | Han, B.B, Inaba, K, Watanabe, S. | Deposit date: | 2023-04-28 | Release date: | 2023-09-20 | Method: | ELECTRON MICROSCOPY (2.92 Å) | Cite: | Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn 2+ uptake into the Golgi apparatus. Nat Commun, 14, 2023
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8J7X
| Cryo-EM structure of hZnT7DeltaHis-loop-Fab complex in zinc-unbound state, determined in outward-facing conformation | Descriptor: | Heavy chain of YN7114-08 Fab, Light chain of YN7114-08 Fab, Zinc transporter 7 | Authors: | Han, B.B, Inaba, K, Watanabe, S. | Deposit date: | 2023-04-28 | Release date: | 2023-09-20 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn 2+ uptake into the Golgi apparatus. Nat Commun, 14, 2023
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8J7V
| Cryo-EM structure of hZnT7-Fab complex in zinc-unbound state, determined in heterogeneous conformations- one subunit in an inward-facing and the other in an outward-facing conformation | Descriptor: | Heavy chain of YN7114-08 Fab, Light chain of YN7114-08 Fab, Zinc transporter 7 | Authors: | Han, B.B, Inaba, K, Watanabe, S. | Deposit date: | 2023-04-28 | Release date: | 2023-09-20 | Method: | ELECTRON MICROSCOPY (2.79 Å) | Cite: | Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn 2+ uptake into the Golgi apparatus. Nat Commun, 14, 2023
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8J7U
| Cryo-EM structure of hZnT7-Fab complex in zinc-bound state, determined in outward-facing conformation | Descriptor: | Heavy chain of YN7114-08 Fab, Light chain of YN7114-08 Fab, ZINC ION, ... | Authors: | Han, B.B, Inaba, K, Watanabe, S. | Deposit date: | 2023-04-28 | Release date: | 2023-09-20 | Method: | ELECTRON MICROSCOPY (3.12 Å) | Cite: | Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn 2+ uptake into the Golgi apparatus. Nat Commun, 14, 2023
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8J80
| Cryo-EM structure of hZnT7-Fab complex in zinc state 1, determined in heterogeneous conformations- one subunit in an inward-facing zinc-bound and the other in an outward-facing zinc-unbound conformation | Descriptor: | Heavy chain of YN7114-08 Fab, Light chain of YN7114-08 Fab, ZINC ION, ... | Authors: | Han, B.B, Inaba, K, Watanabe, S. | Deposit date: | 2023-04-28 | Release date: | 2023-09-20 | Method: | ELECTRON MICROSCOPY (2.68 Å) | Cite: | Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn 2+ uptake into the Golgi apparatus. Nat Commun, 14, 2023
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8J7T
| Cryo-EM structure of hZnT7-Fab complex in zinc-unbound state, determined in outward-facing conformation | Descriptor: | Heavy chain of YN7114-08 Fab, Light chain of YN7114-08 Fab, Zinc transporter 7 | Authors: | Han, B.B, Inaba, K, Watanabe, S. | Deposit date: | 2023-04-28 | Release date: | 2023-09-20 | Method: | ELECTRON MICROSCOPY (2.2 Å) | Cite: | Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn 2+ uptake into the Golgi apparatus. Nat Commun, 14, 2023
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8J7Y
| Cryo-EM structure of hZnT7DeltaHis-loop-Fab complex in zinc-bound state, determined in outward-facing conformation | Descriptor: | Heavy chain of YN7114-08 Fab, Light chain of YN7114-08 Fab, ZINC ION, ... | Authors: | Han, B.B, Inaba, K, Watanabe, S. | Deposit date: | 2023-04-28 | Release date: | 2023-09-20 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn 2+ uptake into the Golgi apparatus. Nat Commun, 14, 2023
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4ZXT
| Complex of ERK2 with catechol | Descriptor: | AMMONIUM ION, CATECHOL, Mitogen-activated protein kinase 1, ... | Authors: | Kurinov, I, Malakhova, M. | Deposit date: | 2015-05-20 | Release date: | 2016-05-25 | Last modified: | 2016-10-05 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A natural small molecule, catechol, induces c-Myc degradation by directly targeting ERK2 in lung cancer. Oncotarget, 7, 2016
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4H6J
| Identification of Cys 255 in HIF-1 as a novel site for development of covalent inhibitors of HIF-1 /ARNT PasB domain protein-protein interaction. | Descriptor: | ARYL HYDROCARBON NUCLEAR TRANSLOCATOR, HYPOXIA INDUCIBLE FACTOR 1-ALPHA | Authors: | Cardoso, R, Love, R.A, Nilsson, C, Bergqvist, S, Nowlin, D, Yan, J, Liu, K, Zhu, J, Chen, P, Deng, Y.-L, Dyson, H.J, Greig, M.J, Brooun, A. | Deposit date: | 2012-09-19 | Release date: | 2012-12-05 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | Identification of Cys255 in HIF-1 alpha as a novel site for development of covalent inhibitors of HIF-1 alpha /ARNT PasB domain protein-protein interaction. Protein Sci., 21, 2012
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3Q16
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6B57
| tudor in complex with ligand | Descriptor: | Tudor and KH domain-containing protein, UNKNOWN ATOM OR ION | Authors: | Zhang, H, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | Deposit date: | 2017-09-28 | Release date: | 2017-11-01 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Structural basis for arginine methylation-independent recognition of PIWIL1 by TDRD2. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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7XGY
| cryo-EM structure of hemoglobin | Descriptor: | Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Liu, N, Wang, H.W. | Deposit date: | 2022-04-07 | Release date: | 2022-11-09 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Uniform thin ice on ultraflat graphene for high-resolution cryo-EM. Nat.Methods, 20, 2023
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6KK1
| Structure of thermal-stabilised(M8) human GLP-1 receptor transmembrane domain | Descriptor: | Glucagon-like peptide 1 receptor,Endolysin,Glucagon-like peptide 1 receptor, N-{4-[(R)-(3,3-dimethylcyclobutyl)({6-[4-(trifluoromethyl)-1H-imidazol-1-yl]pyridin-3-yl}amino)methyl]benzene-1-carbonyl}-beta-alanine | Authors: | Song, G. | Deposit date: | 2019-07-23 | Release date: | 2019-11-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Mutagenesis facilitated crystallization of GLP-1R. Iucrj, 6, 2019
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6KK7
| Structure of thermal-stabilised(M6) human GLP-1 receptor transmembrane domain | Descriptor: | Glucagon-like peptide 1 receptor,Endolysin,Glucagon-like peptide 1 receptor, N-{4-[(R)-(3,3-dimethylcyclobutyl)({6-[4-(trifluoromethyl)-1H-imidazol-1-yl]pyridin-3-yl}amino)methyl]benzene-1-carbonyl}-beta-alanine | Authors: | Song, G. | Deposit date: | 2019-07-23 | Release date: | 2019-11-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Mutagenesis facilitated crystallization of GLP-1R. Iucrj, 6, 2019
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6KJV
| Structure of thermal-stabilised(M9) human GLP-1 receptor transmembrane domain | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Glucagon-like peptide 1 receptor,Endolysin,Glucagon-like peptide 1 receptor, N-{4-[(R)-(3,3-dimethylcyclobutyl)({6-[4-(trifluoromethyl)-1H-imidazol-1-yl]pyridin-3-yl}amino)methyl]benzene-1-carbonyl}-beta-alanine | Authors: | Song, G. | Deposit date: | 2019-07-23 | Release date: | 2019-11-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Mutagenesis facilitated crystallization of GLP-1R. Iucrj, 6, 2019
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