5D9W
| Dehydroascorbate reductase (OsDHAR) complexed with ASA | Descriptor: | ASCORBIC ACID, Dehydroascorbate reductase | Authors: | Do, H, Lee, J.H. | Deposit date: | 2015-08-19 | Release date: | 2016-02-03 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.6897 Å) | Cite: | Structural understanding of the recycling of oxidized ascorbate by dehydroascorbate reductase (OsDHAR) from Oryza sativa L. japonica Sci Rep, 6, 2016
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5D9T
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5D9X
| Dehydroascorbate reductase complexed with GSH | Descriptor: | CALCIUM ION, Dehydroascorbate reductase, GLUTATHIONE | Authors: | Do, H, Lee, J.H. | Deposit date: | 2015-08-19 | Release date: | 2016-02-03 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Structural understanding of the recycling of oxidized ascorbate by dehydroascorbate reductase (OsDHAR) from Oryza sativa L. japonica Sci Rep, 6, 2016
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5BVT
| Palmitate-bound pFABP5 | Descriptor: | Epidermal fatty acid-binding protein, PALMITOLEIC ACID | Authors: | Lee, J.H, Lee, C.W, Do, H. | Deposit date: | 2015-06-05 | Release date: | 2015-08-05 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Structural basis for the ligand-binding specificity of fatty acid-binding proteins (pFABP4 and pFABP5) in gentoo penguin Biochem.Biophys.Res.Commun., 465, 2015
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5BVS
| Linoleate-bound pFABP4 | Descriptor: | Fatty acid-binding protein, LINOLEIC ACID | Authors: | Lee, J.H, Lee, C.W, Do, H. | Deposit date: | 2015-06-05 | Release date: | 2015-08-05 | Last modified: | 2015-09-16 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis for the ligand-binding specificity of fatty acid-binding proteins (pFABP4 and pFABP5) in gentoo penguin Biochem.Biophys.Res.Commun., 465, 2015
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4ZMR
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4ZMS
| Structure of the full-length response regulator spr1814 in complex with a phosphate analogue and B3C | Descriptor: | 5-amino-2,4,6-tribromobenzene-1,3-diyl dihydroperoxide, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... | Authors: | Chi, Y.M, Park, A. | Deposit date: | 2015-05-04 | Release date: | 2016-04-27 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural characterization of the full-length response regulator spr1814 in complex with a phosphate analogue reveals a novel conformational plasticity of the linker region Biochem.Biophys.Res.Commun., 473, 2016
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6JZL
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6VA3
| Solution Structure of the Tau pre-mRNA Exon 10 Splicing Regulatory Element Bound to MQC | Descriptor: | 4-[(3-methoxyphenyl)amino]-2-methylquinoline-6-carboximidamide, RNA (5'-R(*CP*AP*CP*AP*CP*GP*UP*CP*GP*G)-3'), RNA (5'-R(*CP*CP*GP*GP*CP*AP*GP*UP*GP*UP*G)-3') | Authors: | Chen, J.L, Fountain, M.A, Disney, M.D. | Deposit date: | 2019-12-16 | Release date: | 2020-05-20 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Design, Optimization, and Study of Small Molecules That Target Tau Pre-mRNA and Affect Splicing. J.Am.Chem.Soc., 142, 2020
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6VA2
| Solution Structure of the Tau pre-mRNA Exon 10 Splicing Regulatory Element Bound to MH5 | Descriptor: | (2E,2'E)-2,2'-{dibenzo[b,d]thiene-2,8-diyldi[(1E)eth-1-yl-1-ylidene]}bis(N-methylhydrazine-1-carboximidamide), RNA (5'-R(*CP*AP*CP*AP*CP*GP*UP*CP*GP*G)-3'), RNA (5'-R(*CP*CP*GP*GP*CP*AP*GP*UP*GP*UP*G)-3') | Authors: | Chen, J.L, Fountain, M.A, Disney, M.D. | Deposit date: | 2019-12-16 | Release date: | 2020-05-20 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Design, Optimization, and Study of Small Molecules That Target Tau Pre-mRNA and Affect Splicing. J.Am.Chem.Soc., 142, 2020
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6VA1
| Solution Structure of the Tau pre-mRNA Exon 10 Splicing Regulatory Element | Descriptor: | RNA (5'-R(*CP*AP*CP*AP*CP*GP*UP*CP*GP*G)-3'), RNA (5'-R(*CP*CP*GP*GP*CP*AP*GP*UP*GP*UP*G)-3') | Authors: | Chen, J.L, Fountain, M.A, Disney, M.D. | Deposit date: | 2019-12-16 | Release date: | 2020-05-20 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Design, Optimization, and Study of Small Molecules That Target Tau Pre-mRNA and Affect Splicing. J.Am.Chem.Soc., 142, 2020
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6VA4
| Solution Structure of the Tau pre-mRNA Exon 10 Splicing Regulatory Element Bound to MIP | Descriptor: | N-[3-(8-methoxy-4-oxo-4,5-dihydro-3H-pyrimido[5,4-b]indol-3-yl)propyl]-N-methylcyclohexanaminium, RNA (5'-R(*CP*AP*CP*AP*CP*GP*UP*CP*GP*G)-3'), RNA (5'-R(*CP*CP*GP*GP*CP*AP*GP*UP*GP*UP*G)-3') | Authors: | Chen, J.L, Fountain, M.A, Disney, M.D. | Deposit date: | 2019-12-16 | Release date: | 2020-05-20 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Design, Optimization, and Study of Small Molecules That Target Tau Pre-mRNA and Affect Splicing. J.Am.Chem.Soc., 142, 2020
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5IT1
| Streptomyces peucetius CYP105P2 complex with biphenyl compound | Descriptor: | 4,4'-PROPANE-2,2-DIYLDIPHENOL, PROTOPORPHYRIN IX CONTAINING FE, Putative cytochrome P450 | Authors: | Lee, C.W, Lee, J.H. | Deposit date: | 2016-03-16 | Release date: | 2016-06-08 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structure of Cytochrome P450 (CYP105P2) from Streptomyces peucetius and Its Conformational Changes in Response to Substrate Binding Int J Mol Sci, 17, 2016
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5Z2E
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5Z2F
| NADPH/PDA bound Dihydrodipicolinate reductase from Paenisporosarcina sp. TG-14 | Descriptor: | Dihydrodipicolinate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PYRIDINE-2,6-DICARBOXYLIC ACID | Authors: | Lee, J.H, Lee, C.W, Park, S. | Deposit date: | 2018-01-02 | Release date: | 2018-06-27 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of dihydrodipicolinate reductase (PaDHDPR) from Paenisporosarcina sp. TG-14: structural basis for NADPH preference as a cofactor Sci Rep, 8, 2018
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5Z2D
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6NSL
| CRYSTAL STRUCTURE OF TYROSINE KINASE 2 JH2 (PSEUDO KINASE DOMAIN) COMPLEXED WITH Compound-6c AKA 6-((1-(4-CYANOPHENY L)-2-OXO-1,2-DIHYDRO-3-PYRIDINYL)AMINO)-N-CYCLOPROPYL-8-(M ETHYLAMINO)IMIDAZO[1,2-B]PYRIDAZINE-3-CARBOXAMIDE | Descriptor: | 6-{[1-(4-cyanophenyl)-2-oxo-1,2-dihydropyridin-3-yl]amino}-N-cyclopropyl-8-(methylamino)imidazo[1,2-b]pyridazine-3-carboxamide, Non-receptor tyrosine-protein kinase TYK2, SULFATE ION | Authors: | Muckelbauer, J.M, Khan, J.A. | Deposit date: | 2019-01-25 | Release date: | 2020-01-29 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Identification of Imidazo[1,2-b]pyridazine Derivatives as Potent, Selective, and Orally Active Tyk2 JH2 Inhibitors. Acs Med.Chem.Lett., 10, 2019
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7EZN
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8W77
| Human Consensus Olfactory Receptor OR52c in apo state, OR52c only | Descriptor: | Human Consensus Olfactory Receptor OR52c in apo state, receptor only,Soluble cytochrome b562 | Authors: | Choi, C.W, Bae, J, Choi, H.-J, Kim, J. | Deposit date: | 2023-08-30 | Release date: | 2023-12-20 | Method: | ELECTRON MICROSCOPY (3.61 Å) | Cite: | Understanding the molecular mechanisms of odorant binding and activation of the human OR52 family. Nat Commun, 14, 2023
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5WQ0
| Receiver domain of Spo0A from Paenisporosarcina sp. TG-14 | Descriptor: | MAGNESIUM ION, Stage 0 sporulation protein | Authors: | Lee, J.H, Lee, C.W. | Deposit date: | 2016-11-22 | Release date: | 2017-03-22 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.604 Å) | Cite: | Crystal structure of the inactive state of the receiver domain of Spo0A from Paenisporosarcina sp. TG-14, a psychrophilic bacterium isolated from an Antarctic glacier J. Microbiol., 55, 2017
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3LJU
| Crystal structure of full length centaurin alpha-1 bound with the head group of PIP3 | Descriptor: | (2R)-3-{[(R)-{[(1S,2S,3R,4S,5S,6S)-2,6-dihydroxy-3,4,5-tris(phosphonooxy)cyclohexyl]oxy}(hydroxy)phosphoryl]oxy}propane -1,2-diyl dioctanoate, Arf-GAP with dual PH domain-containing protein 1, ZINC ION | Authors: | Shen, L, Tong, Y, Tempel, W, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2010-01-26 | Release date: | 2010-11-24 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.702 Å) | Cite: | Phosphorylation-independent dual-site binding of the FHA domain of KIF13 mediates phosphoinositide transport via centaurin alpha1. Proc.Natl.Acad.Sci.USA, 107, 2010
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2CKX
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3QAW
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4JNB
| Crystal structure of the Catalytic Domain of Human DUSP12 | Descriptor: | Dual specificity protein phosphatase 12, SULFATE ION | Authors: | Jeon, T.J, Chien, P.N, Ku, B, Kim, S.J, Ryu, S.E. | Deposit date: | 2013-03-15 | Release date: | 2014-03-26 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The family-wide structure and function of human dual-specificity protein phosphatases. Acta Crystallogr.,Sect.D, 70, 2014
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4JMJ
| Structure of dusp11 | Descriptor: | CHLORIDE ION, PHOSPHATE ION, RNA/RNP complex-1-interacting phosphatase | Authors: | Jeong, D.G, Kim, S.J, Ryu, S.E. | Deposit date: | 2013-03-14 | Release date: | 2014-02-26 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.382 Å) | Cite: | The family-wide structure and function of human dual-specificity protein phosphatases. Acta Crystallogr.,Sect.D, 70, 2014
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