1CPZ
 
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8BFG
 | | Solution structure of human apo/Calmodulin G113R (G114R) | | Descriptor: | Calmodulin-1 | | Authors: | Wimmer, R, Holler, C.V, Petersson, N.M, Brohus, M.B, Niemelae, M, Overgaard, M.T, Iwai, H. | | Deposit date: | 2022-10-25 | | Release date: | 2023-10-04 | | Last modified: | 2024-01-17 | | Method: | SOLUTION NMR | | Cite: | Allosteric changes in protein stability and dynamics as pathogenic mechanism for calmodulin variants not affecting Ca 2+ coordinating residues.
Cell Calcium, 117, 2023
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8BD2
 | | Calcium-bound Calmodulin variant G113R | | Descriptor: | CALCIUM ION, Calmodulin-3 | | Authors: | Wimmer, R, Holler, C.V, Petersson, N.M, Iwai, H, Niemelae, M.A, Brohus, M, Overgaard, M.T. | | Deposit date: | 2022-10-18 | | Release date: | 2023-11-08 | | Last modified: | 2024-01-17 | | Method: | SOLUTION NMR | | Cite: | Allosteric changes in protein stability and dynamics as pathogenic mechanism for calmodulin variants not affecting Ca 2+ coordinating residues.
Cell Calcium, 117, 2023
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5LW4
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6GDL
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6GDK
 | | Calcium bound form of human calmodulin mutant F141L | | Descriptor: | CALCIUM ION, Calmodulin-1 | | Authors: | Grachov, O, Holt, C, Overgaard, M.T, Wimmer, R. | | Deposit date: | 2018-04-23 | | Release date: | 2018-10-17 | | Last modified: | 2024-06-19 | | Method: | SOLUTION NMR | | Cite: | Arrhythmia mutations in calmodulin cause conformational changes that affect interactions with the cardiac voltage-gated calcium channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6TWE
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6Y94
 | | Ca2+-bound Calmodulin mutant N53I | | Descriptor: | CALCIUM ION, Calmodulin | | Authors: | Holt, C, Nielsen, L.H, Lau, K, Brohus, M, Sorensen, A.B, Larsen, K.T, Sommer, C, Petegem, F.V, Overgaard, M.T, Wimmer, R. | | Deposit date: | 2020-03-06 | | Release date: | 2020-04-29 | | Last modified: | 2024-06-19 | | Method: | SOLUTION NMR | | Cite: | The arrhythmogenic N53I variant subtly changes the structure and dynamics in the calmodulin N-terminal domain, altering its interaction with the cardiac ryanodine receptor.
J.Biol.Chem., 295, 2020
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6Y4P
 | | Calmodulin N53I variant bound to cardiac ryanodine receptor (RyR2) calmodulin binding domain | | Descriptor: | CALCIUM ION, Calmodulin-1, Ryanodine receptor 2 | | Authors: | Lau, K, Nielsen, L.H, Holt, C, Brohus, M, Sorensen, A.B, Larsen, K.T, Sommer, C, Van Petegem, F, Overgaard, M.T, Wimmer, R. | | Deposit date: | 2020-02-21 | | Release date: | 2020-04-29 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.13325572 Å) | | Cite: | The arrhythmogenic N53I variant subtly changes the structure and dynamics in the calmodulin N-terminal domain, altering its interaction with the cardiac ryanodine receptor.
J.Biol.Chem., 295, 2020
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6Y4O
 | | Calmodulin bound to cardiac ryanodine receptor (RyR2) calmodulin binding domain | | Descriptor: | CALCIUM ION, Calmodulin-2, Ryanodine receptor 2 | | Authors: | Lau, K, Nielsen, L.H, Holt, C, Brohus, M, Sorensen, A.B, Larsen, K.T, Sommer, C, Van Petegem, F, Overgaard, M.T, Wimmer, R. | | Deposit date: | 2020-02-21 | | Release date: | 2020-04-29 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.83549082 Å) | | Cite: | The arrhythmogenic N53I variant subtly changes the structure and dynamics in the calmodulin N-terminal domain, altering its interaction with the cardiac ryanodine receptor.
J.Biol.Chem., 295, 2020
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6Y95
 | | Ca2+-free Calmodulin mutant N53I | | Descriptor: | Calmodulin | | Authors: | Holt, C, Hamborg, L.N, Lau, K, Brohus, M, Sorensen, A.B, Larsen, K.T, Sommer, C, Petegem, F.V, Overgaard, M.T, Wimmer, R. | | Deposit date: | 2020-03-06 | | Release date: | 2020-04-29 | | Last modified: | 2024-06-19 | | Method: | SOLUTION NMR | | Cite: | The arrhythmogenic N53I variant subtly changes the structure and dynamics in the calmodulin N-terminal domain, altering its interaction with the cardiac ryanodine receptor.
J.Biol.Chem., 295, 2020
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2AGM
 | | Solution structure of the R-module from AlgE4 | | Descriptor: | Poly(beta-D-mannuronate) C5 epimerase 4 | | Authors: | Aachmann, F.L, Svanem, B.I, Guntert, P, Petersen, S.B, Valla, S, Wimmer, R. | | Deposit date: | 2005-07-27 | | Release date: | 2006-01-10 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | NMR structure of the R-module: a parallel beta-roll subunit from an Azotobacter vinelandii mannuronan C-5 epimerase.
J.Biol.Chem., 281, 2006
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2ML3
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2MWQ
 | | Solution structure of PsbQ from spinacia oleracea | | Descriptor: | Oxygen-evolving enhancer protein 3, chloroplastic | | Authors: | Rathner, P, Mueller, N, Wimmer, R, Chandra, K. | | Deposit date: | 2014-11-19 | | Release date: | 2015-07-29 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Solution NMR and molecular dynamics reveal a persistent alpha helix within the dynamic region of PsbQ from photosystem II of higher plants.
Proteins, 83, 2015
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2MJS
 | | Anoplin R5K T8W in DPC micelles | | Descriptor: | Anoplin, UNKNOWN ATOM OR ION, dodecyl 2-(trimethylammonio)ethyl phosphate | | Authors: | Uggerhoej, L, Poulsen, T.J, Wimmer, R. | | Deposit date: | 2014-01-16 | | Release date: | 2014-12-03 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Rational Design of Alpha-Helical Antimicrobial Peptides: Do's and Don'ts.
Chembiochem, 16, 2015
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2MJR
 | | Anoplin R5W structure in DPC micelles | | Descriptor: | Anoplin, UNKNOWN ATOM OR ION, dodecyl 2-(trimethylammonio)ethyl phosphate | | Authors: | Uggerhoej, L, Poulsen, T.J, Wimmer, R. | | Deposit date: | 2014-01-16 | | Release date: | 2014-12-03 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Rational Design of Alpha-Helical Antimicrobial Peptides: Do's and Don'ts.
Chembiochem, 16, 2015
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2MH5
 | | Structure and NMR assignments of lantibiotic NAI-107 in DPC micelles | | Descriptor: | Lantibiotic 107891, dodecyl 2-(trimethylammonio)ethyl phosphate | | Authors: | Munch, D, Muller, A, Schneider, T, Kohl, B, Wenzel, M, Bandow, J, Maffioli, S, Sosio, M, Donadio, S, Wimmer, R, Sahl, H. | | Deposit date: | 2013-11-18 | | Release date: | 2014-03-05 | | Last modified: | 2024-07-10 | | Method: | SOLUTION NMR | | Cite: | The Lantibiotic NAI-107 Binds to Bactoprenol-bound Cell Wall Precursors and Impairs Membrane Functions.
J.Biol.Chem., 289, 2014
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2MJQ
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2LT8
 | | Eurocin solution structure | | Descriptor: | eurocin | | Authors: | Oeemig, J.S, Lynggaard, C, Knudsen, D.H, Hansen, F.T, Noergaard, K.D, Schneider, T, Vad, B.S, Neve, S, Kristensen, H, Sahl, H, Otzen, D.E, Wimmer, R. | | Deposit date: | 2012-05-15 | | Release date: | 2012-10-31 | | Last modified: | 2024-10-30 | | Method: | SOLUTION NMR | | Cite: | Eurocin, a New Fungal Defensin: STRUCTURE, LIPID BINDING, AND ITS MODE OF ACTION.
J.Biol.Chem., 287, 2012
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2MJT
 | | Anoplin R5F T8W in DPC micelles | | Descriptor: | Anoplin, UNKNOWN ATOM OR ION, dodecyl 2-(trimethylammonio)ethyl phosphate | | Authors: | Uggerhoej, L, Poulsen, T.J, Wimmer, R. | | Deposit date: | 2014-01-16 | | Release date: | 2014-12-03 | | Last modified: | 2024-10-16 | | Method: | SOLUTION NMR | | Cite: | Rational Design of Alpha-Helical Antimicrobial Peptides: Do's and Don'ts.
Chembiochem, 16, 2015
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2ML2
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2MMJ
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2ML1
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2MN9
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2MN8
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