7YAN
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3JB8
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![BU of 3jb8 by Molmil](/molmil-images/mine/3jb8) | Insight into Three-dimensional structure of Maize Chlorotic Mottle Virus Revealed by Single Particle Analysis | Descriptor: | Coat protein | Authors: | Wang, C.Y, Zhang, Q.F, Gao, Y.Z, Zhou, X.P, Ji, G, Huang, X.J, Hong, J, Zhang, C.X. | Deposit date: | 2015-08-04 | Release date: | 2016-07-13 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Insight into the three-dimensional structure of maize chlorotic mottle virus revealed by Cryo-EM single particle analysis. Virology, 485, 2015
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4H27
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7CJX
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![BU of 7cjx by Molmil](/molmil-images/mine/7cjx) | UDP-glucuronosyltransferase 2B15 C-terminal domain-L446S | Descriptor: | L(+)-TARTARIC ACID, UDP-glucuronosyltransferase 2B15 | Authors: | Wang, C.Y, Zhang, L. | Deposit date: | 2020-07-14 | Release date: | 2021-07-14 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.986414 Å) | Cite: | Structure of UDP-glucuronosyltransferase 2B15 C-terminal domain L446S at 1.99 Angstroms resolution To Be Published
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5DNP
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![BU of 5dnp by Molmil](/molmil-images/mine/5dnp) | Crystal structure of Mmi1 YTH domain | Descriptor: | PHOSPHATE ION, YTH domain-containing protein mmi1 | Authors: | Wang, C.Y, Zhu, Y.W, Shi, Y.Y, Wu, J.H. | Deposit date: | 2015-09-10 | Release date: | 2016-04-06 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | A novel RNA-binding mode of the YTH domain reveals the mechanism for recognition of determinant of selective removal by Mmi1 Nucleic Acids Res., 44, 2016
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5DNO
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![BU of 5dno by Molmil](/molmil-images/mine/5dno) | Crystal structure of Mmi1 YTH domain complex with RNA | Descriptor: | RNA (5'-R(*CP*UP*UP*AP*AP*AP*C)-3'), YTH domain-containing protein mmi1 | Authors: | Wang, C.Y, Zhu, Y.W, Wu, J.H, Shi, Y.Y. | Deposit date: | 2015-09-10 | Release date: | 2016-04-06 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A novel RNA-binding mode of the YTH domain reveals the mechanism for recognition of determinant of selective removal by Mmi1 Nucleic Acids Res., 44, 2016
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7EZO
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4Z7F
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![BU of 4z7f by Molmil](/molmil-images/mine/4z7f) | Crystal structure of FolT bound with folic acid | Descriptor: | FOLIC ACID, Folate ECF transporter | Authors: | Zhao, Q, Wang, C.C, Wang, C.Y, Zhang, P. | Deposit date: | 2015-04-07 | Release date: | 2015-07-29 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.194 Å) | Cite: | Structures of FolT in substrate-bound and substrate-released conformations reveal a gating mechanism for ECF transporters Nat Commun, 6, 2015
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3IYO
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![BU of 3iyo by Molmil](/molmil-images/mine/3iyo) | Cryo-EM model of virion-sized HEV virion-sized capsid | Descriptor: | Capsid protein | Authors: | Xing, L, Mayazaki, N, Li, T.C, Simons, M.N, Wall, J.S, Moore, M, Wang, C.Y, Takeda, N, Wakita, T, Miyamura, T, Cheng, R.H. | Deposit date: | 2010-03-19 | Release date: | 2010-08-18 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (10.5 Å) | Cite: | Structural basis for the RNA-dependent assembly pathway of hepatitis E virion-sized particles J.Biol.Chem., 2010
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6L9I
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8JNY
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8JNZ
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![BU of 8jnz by Molmil](/molmil-images/mine/8jnz) | Human ADP-ribosyltransferase 1 (PARP1) catalytic domain bound to a pyrazolopyrimidine carboxamide inhibitor | Descriptor: | 6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide, Poly [ADP-ribose] polymerase 1, processed C-terminus, ... | Authors: | Wang, X.Y, Wang, C.Y, Zhou, J, Xu, B.L. | Deposit date: | 2023-06-06 | Release date: | 2024-06-12 | Method: | X-RAY DIFFRACTION (2.84 Å) | Cite: | Human ADP-ribosyltransferase 1 (PARP1) catalytic domain bound to a pyrazolopyrimidine carboxamide inhibitor To Be Published
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6LPW
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6LPV
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8DHH
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![BU of 8dhh by Molmil](/molmil-images/mine/8dhh) | DHODH IN COMPLEX WITH LIGAND 29 | Descriptor: | (6M)-N-(3-chloro-2-methoxy-5-methylpyridin-4-yl)-6-[4-ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-5-fluoro-2-{[(2S)-1,1,1-trifluoropropan-2-yl]oxy}pyridine-3-carboxamide, ACETATE ION, Dihydroorotate dehydrogenase (quinone), ... | Authors: | Shaffer, P.L. | Deposit date: | 2022-06-27 | Release date: | 2022-08-17 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | N -Heterocyclic 3-Pyridyl Carboxamide Inhibitors of DHODH for the Treatment of Acute Myelogenous Leukemia. J.Med.Chem., 65, 2022
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8DHG
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![BU of 8dhg by Molmil](/molmil-images/mine/8dhg) | DHODH IN COMPLEX WITH LIGAND 19 | Descriptor: | (6M)-N-(2-chloro-4-methylpyridin-3-yl)-6-[4-ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-5-fluoro-2-{[(2S)-1,1,1-trifluoropropan-2-yl]oxy}pyridine-3-carboxamide, ACETATE ION, Dihydroorotate dehydrogenase (quinone), ... | Authors: | Shaffer, P.L. | Deposit date: | 2022-06-27 | Release date: | 2022-08-17 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | N -Heterocyclic 3-Pyridyl Carboxamide Inhibitors of DHODH for the Treatment of Acute Myelogenous Leukemia. J.Med.Chem., 65, 2022
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8DHF
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![BU of 8dhf by Molmil](/molmil-images/mine/8dhf) | DHODH IN COMPLEX WITH LIGAND 11 | Descriptor: | (6M)-N-(2-chloro-6-fluorophenyl)-6-[4-ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-5-fluoro-2-{[(2S)-1,1,1-trifluoropropan-2-yl]oxy}pyridine-3-carboxamide, ACETATE ION, Dihydroorotate dehydrogenase (quinone), ... | Authors: | Shaffer, P.L. | Deposit date: | 2022-06-27 | Release date: | 2022-08-17 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | N -Heterocyclic 3-Pyridyl Carboxamide Inhibitors of DHODH for the Treatment of Acute Myelogenous Leukemia. J.Med.Chem., 65, 2022
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6W2E
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![BU of 6w2e by Molmil](/molmil-images/mine/6w2e) | Structures of Capsid and Capsid-Associated Tegument Complex inside the Epstein-Barr Virus | Descriptor: | Capsid vertex component 1, Capsid vertex component 2, Large tegument protein deneddylase, ... | Authors: | Liu, W, Cui, Y.X, Wang, C.Y, Li, Z.H, Gong, D.Y, Dai, X.H, Bi, G.Q, Sun, R, Zhou, Z.H. | Deposit date: | 2020-03-05 | Release date: | 2020-07-15 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Structures of capsid and capsid-associated tegument complex inside the Epstein-Barr virus. Nat Microbiol, 5, 2020
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6W19
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![BU of 6w19 by Molmil](/molmil-images/mine/6w19) | Structures of Capsid and Capsid-Associated Tegument Complex inside the Epstein-Barr Virus | Descriptor: | Major capsid protein, Small capsomere-interacting protein, Triplex capsid protein 1, ... | Authors: | Liu, W, Cui, Y.X, Wang, C.Y, Li, Z.H, Gong, D.Y, Dai, X.H, Bi, G.Q, Sun, R, Zhou, Z.H. | Deposit date: | 2020-03-03 | Release date: | 2020-07-15 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (5.5 Å) | Cite: | Structures of capsid and capsid-associated tegument complex inside the Epstein-Barr virus. Nat Microbiol, 5, 2020
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6W2D
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![BU of 6w2d by Molmil](/molmil-images/mine/6w2d) | Structures of Capsid and Capsid-Associated Tegument Complex inside the Epstein-Barr Virus | Descriptor: | Capsid vertex component 1, Capsid vertex component 2, Large tegument protein deneddylase, ... | Authors: | Liu, W, Cui, Y.X, Wang, C.Y, Li, Z.H, Gong, D.Y, Dai, X.H, Bi, G.Q, Sun, R, Zhou, Z.H. | Deposit date: | 2020-03-05 | Release date: | 2020-07-15 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structures of capsid and capsid-associated tegument complex inside the Epstein-Barr virus. Nat Microbiol, 5, 2020
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5IGM
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![BU of 5igm by Molmil](/molmil-images/mine/5igm) | Crystal structure of the bromodomain of human BRD9 in complex with bromosporine (BSP) | Descriptor: | Bromodomain-containing protein 9, Bromosporine | Authors: | Tallant, C, Filippakopoulos, P, Picaud, S, Nunez-Alonso, G, von Delft, F, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2016-02-28 | Release date: | 2016-10-19 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Promiscuous targeting of bromodomains by bromosporine identifies BET proteins as master regulators of primary transcription response in leukemia. Sci Adv, 2, 2016
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5IGL
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![BU of 5igl by Molmil](/molmil-images/mine/5igl) | Crystal structure of the second bromodomain of human TAF1L in complex with bromosporine (BSP) | Descriptor: | Bromosporine, Transcription initiation factor TFIID subunit 1-like | Authors: | Filippakopoulos, P, Picaud, S, Felletar, I, Krojer, T, Tallant, C, von Delft, F, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2016-02-28 | Release date: | 2016-10-19 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Promiscuous targeting of bromodomains by bromosporine identifies BET proteins as master regulators of primary transcription response in leukemia. Sci Adv, 2, 2016
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5IGK
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![BU of 5igk by Molmil](/molmil-images/mine/5igk) | Crystal structure of the first bromodomain of human BRD4 in complex with bromosporine (BSP) | Descriptor: | 1,2-ETHANEDIOL, Bromodomain-containing protein 4, Bromosporine | Authors: | Filippakopoulos, P, Picaud, S, Felletar, I, von Delft, F, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2016-02-28 | Release date: | 2016-10-19 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Promiscuous targeting of bromodomains by bromosporine identifies BET proteins as master regulators of primary transcription response in leukemia. Sci Adv, 2, 2016
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4COS
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![BU of 4cos by Molmil](/molmil-images/mine/4cos) | Crystal structure of the PHD-Bromo-PWWP cassette of human PRKCBP1 | Descriptor: | 1,4-DIETHYLENE DIOXIDE, PROTEIN KINASE C-BINDING PROTEIN 1, ZINC ION | Authors: | Krojer, T, Savitsky, P, Newman, J.A, Cooper, C.D.O, von Delft, F, Arrowsmith, C.H, Bountra, C, Edwards, A, Filippakopoulos, P. | Deposit date: | 2014-01-30 | Release date: | 2014-03-05 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Multivalent Histone and DNA Engagement by a PHD/BRD/PWWP Triple Reader Cassette Recruits ZMYND8 to K14ac-Rich Chromatin. Cell Rep, 17, 2016
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8XAI
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