8JNY

Mutated human ADP-ribosyltransferase 2 (PARP2) catalytic domain bound to a pyrazolopyrimidine carboxamide inhibitor

Summary for 8JNY

• Entry DOI: 10.2210/pdb8jny/pdb
• Descriptor: Poly [ADP-ribose] polymerase 2, 6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide (2 entities in total)
• Functional Keywords: dna adp-ribosyltransferase 2, parp2, parp inhibitor, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 80284.17

Authors

Wang, X.Y.,Wang, C.Y.,Zhou, J.,Xu, B.L. (deposition date: 2023-06-06, release date: 2024-06-12)

• Primary citation: Wang, X.Y.,Wang, C.Y.,Zhou, J.,Xu, B.L.; Mutated human ADP-ribosyltransferase 2 (PARP2) catalytic domain bound to a pyrazolopyrimidine carboxamide inhibitor; To Be Published,

Experimental method

X-RAY DIFFRACTION (3.2 Å)