2WNA
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2JJA
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![BU of 2jja by Molmil](/molmil-images/mine/2jja) | Crystal structure of GNA with synthetic copper base pair | Descriptor: | COBALT HEXAMMINE(III), COPPER (II) ION, GNA, ... | Authors: | Schlegel, M.K, Essen, L.-O, Meggers, E. | Deposit date: | 2008-03-28 | Release date: | 2008-07-22 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Duplex Structure of a Minimal Nucleic Acid. J.Am.Chem.Soc., 130, 2008
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2XC6
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7LO9
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![BU of 7lo9 by Molmil](/molmil-images/mine/7lo9) | RNA dodecamer containing a GNA A residue | Descriptor: | Chains: A,B,C,D | Authors: | Harp, J.M, Wawrzak, Z, Egli, M. | Deposit date: | 2021-02-09 | Release date: | 2021-12-22 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Overcoming GNA/RNA base-pairing limitations using isonucleotides improves the pharmacodynamic activity of ESC+ GalNAc-siRNAs. Nucleic Acids Res., 49, 2021
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5V2H
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![BU of 5v2h by Molmil](/molmil-images/mine/5v2h) | RNA octamer containing glycol nucleic acid, SgnT | Descriptor: | COBALT HEXAMMINE(III), MAGNESIUM ION, RNA (5'-R(*(CBV)P*GP*AP*AP*(ZTH)P*UP*CP*G)-3') | Authors: | Harp, J.M, Egli, M. | Deposit date: | 2017-03-04 | Release date: | 2017-06-14 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.080013 Å) | Cite: | Chirality Dependent Potency Enhancement and Structural Impact of Glycol Nucleic Acid Modification on siRNA. J. Am. Chem. Soc., 139, 2017
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5V1L
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![BU of 5v1l by Molmil](/molmil-images/mine/5v1l) | Structure of S-GNA dodecamer | Descriptor: | RNA (5'-R(*CP*GP*CP*GP*AP*AP*UP*(ZTH)P*AP*GP*CP*G)-3'), SPERMINE, STRONTIUM ION | Authors: | Pallan, P.S, Egli, M. | Deposit date: | 2017-03-02 | Release date: | 2017-06-14 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Chirality Dependent Potency Enhancement and Structural Impact of Glycol Nucleic Acid Modification on siRNA. J. Am. Chem. Soc., 139, 2017
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5V1K
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![BU of 5v1k by Molmil](/molmil-images/mine/5v1k) | Structure of R-GNA dodecamer | Descriptor: | RNA (5'-R(*CP*GP*CP*GP*AP*AP*(5BU)P*(8RJ)P*AP*GP*CP*G)-3') | Authors: | Pallan, P.S, Egli, M. | Deposit date: | 2017-03-02 | Release date: | 2017-06-21 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.18 Å) | Cite: | Chirality Dependent Potency Enhancement and Structural Impact of Glycol Nucleic Acid Modification on siRNA. J. Am. Chem. Soc., 2017
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8SKQ
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6VEM
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![BU of 6vem by Molmil](/molmil-images/mine/6vem) | Structure of RNA octamer | Descriptor: | COBALT HEXAMMINE(III), Modified Octamer RNA | Authors: | Pallan, P.S, Egli, M. | Deposit date: | 2020-01-02 | Release date: | 2020-11-18 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | Synthesis, chirality-dependent conformational and biological properties of siRNAs containing 5'-(R)- and 5'-(S)-C-methyl-guanosine. Nucleic Acids Res., 48, 2020
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7JJD
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7JJF
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![BU of 7jjf by Molmil](/molmil-images/mine/7jjf) | Sarcin-ricin loop with modified residue. | Descriptor: | MAGNESIUM ION, RNA/DNA (27-mer) | Authors: | Harp, J.M, Pallan, P.S, Egli, M. | Deposit date: | 2020-07-25 | Release date: | 2020-12-23 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Incorporating a Thiophosphate Modification into a Common RNA Tetraloop Motif Causes an Unanticipated Stability Boost. Biochemistry, 59, 2020
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7JJE
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9BF0
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![BU of 9bf0 by Molmil](/molmil-images/mine/9bf0) | MID domain of human Argo2 bound to UTP | Descriptor: | Protein argonaute-2, URIDINE 5'-TRIPHOSPHATE | Authors: | Harp, J.M, Egli, M. | Deposit date: | 2024-04-16 | Release date: | 2024-07-10 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Structure and Stability of Ago2 MID-Nucleotide Complexes: All-in-One (Drop) His 6 -SUMO Tag Removal, Nucleotide Binding, and Crystal Growth. Curr Protoc, 4, 2024
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9BF2
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![BU of 9bf2 by Molmil](/molmil-images/mine/9bf2) | MID domain of Ago2 bound to UMP | Descriptor: | Protein argonaute-2, URIDINE-5'-MONOPHOSPHATE | Authors: | Harp, J.M, Egli, M. | Deposit date: | 2024-04-16 | Release date: | 2024-07-10 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Structure and Stability of Ago2 MID-Nucleotide Complexes: All-in-One (Drop) His 6 -SUMO Tag Removal, Nucleotide Binding, and Crystal Growth. Curr Protoc, 4, 2024
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9BEZ
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![BU of 9bez by Molmil](/molmil-images/mine/9bez) | MID domain of human Argo2 bound to RNA | Descriptor: | Protein argonaute-2, [(3~{S},4~{R},5~{R})-5-[5-methyl-2,4-bis(oxidanylidene)pyrimidin-1-yl]-4-oxidanyl-oxolan-3-yl] [oxidanyl(phosphonooxy)phosphoryl] hydrogen phosphate | Authors: | Harp, J.M, Egli, M. | Deposit date: | 2024-04-16 | Release date: | 2024-07-10 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure and Stability of Ago2 MID-Nucleotide Complexes: All-in-One (Drop) His 6 -SUMO Tag Removal, Nucleotide Binding, and Crystal Growth. Curr Protoc, 4, 2024
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