8PK6
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![BU of 8pk6 by Molmil](/molmil-images/mine/8pk6) | INTS13 complex with ZNF655 | Descriptor: | Integrator complex subunit 13, Zinc finger protein 655 | Authors: | Sabath, K, Jonas, S. | Deposit date: | 2023-06-25 | Release date: | 2024-07-03 | Last modified: | 2024-07-24 | Method: | X-RAY DIFFRACTION (3.21 Å) | Cite: | Basis of gene-specific transcription regulation by the Integrator complex. Mol.Cell, 84, 2024
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8PK5
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![BU of 8pk5 by Molmil](/molmil-images/mine/8pk5) | INTS13-INTS14 complex with ZNF609 | Descriptor: | Integrator complex subunit 13, Integrator complex subunit 14,Zinc finger protein 609, MAGNESIUM ION | Authors: | Sabath, K, Jonas, S. | Deposit date: | 2023-06-25 | Release date: | 2024-07-03 | Last modified: | 2024-07-24 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Basis of gene-specific transcription regulation by the Integrator complex. Mol.Cell, 84, 2024
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8R23
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![BU of 8r23 by Molmil](/molmil-images/mine/8r23) | INTS9-INTS11-BRAT1 complex | Descriptor: | BRCA1-associated ATM activator 1, Integrator complex subunit 11, Integrator complex subunit 9, ... | Authors: | Sabath, K, Qiu, C, Jonas, S. | Deposit date: | 2023-11-02 | Release date: | 2024-07-31 | Last modified: | 2024-08-21 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Assembly mechanism of Integrator's RNA cleavage module. Mol.Cell, 84, 2024
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8R2D
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![BU of 8r2d by Molmil](/molmil-images/mine/8r2d) | Integrator cleavage module assembly intermediate | Descriptor: | BRCA1-associated ATM activator 1, Integrator complex subunit 11, Integrator complex subunit 4, ... | Authors: | Sabath, K, Qiu, C, Jonas, S. | Deposit date: | 2023-11-03 | Release date: | 2024-07-31 | Last modified: | 2024-08-21 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Assembly mechanism of Integrator's RNA cleavage module. Mol.Cell, 84, 2024
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8R22
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![BU of 8r22 by Molmil](/molmil-images/mine/8r22) | INTS9-INTS11-BRAT1-WDR73 complex | Descriptor: | BRCA1-associated ATM activator 1, Integrator complex subunit 11, Integrator complex subunit 9, ... | Authors: | Sabath, K, Qiu, C, Jonas, S. | Deposit date: | 2023-11-02 | Release date: | 2024-07-31 | Last modified: | 2024-08-21 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Assembly mechanism of Integrator's RNA cleavage module. Mol.Cell, 84, 2024
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6SN1
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![BU of 6sn1 by Molmil](/molmil-images/mine/6sn1) | Crystal structure of the human INTS13-INTS14 complex | Descriptor: | Integrator complex subunit 13, Integrator complex subunit 14, SULFATE ION | Authors: | Jonas, S, Sabath, K, Staeubli, M.L. | Deposit date: | 2019-08-23 | Release date: | 2020-07-22 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.54 Å) | Cite: | INTS10-INTS13-INTS14 form a functional module of Integrator that binds nucleic acids and the cleavage module. Nat Commun, 11, 2020
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7P0V
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![BU of 7p0v by Molmil](/molmil-images/mine/7p0v) | Crystal structure of human SF3A1 ubiquitin-like domain in complex with U1 snRNA stem-loop 4 | Descriptor: | Isoform 2 of Splicing factor 3A subunit 1, PENTAETHYLENE GLYCOL, RNA (5'-R(P*GP*GP*GP*GP*AP*CP*UP*GP*CP*GP*UP*UP*CP*GP*CP*GP*CP*UP*UP*UP*CP*CP*CP*C)-3'), ... | Authors: | Sabath, K, de Vries, T, Jonas, S. | Deposit date: | 2021-06-30 | Release date: | 2022-04-20 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | Sequence-specific RNA recognition by an RGG motif connects U1 and U2 snRNP for spliceosome assembly. Proc.Natl.Acad.Sci.USA, 119, 2022
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5FU6
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![BU of 5fu6 by Molmil](/molmil-images/mine/5fu6) | NOT module of the human CCR4-NOT complex (Crystallization mutant) | Descriptor: | CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 2, CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 3 | Authors: | Raisch, T, Bhandari, D, Sabath, K, Helms, S, Valkov, E, Weichenrieder, O, Izaurralde, E. | Deposit date: | 2016-01-21 | Release date: | 2016-03-23 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Distinct Modes of Recruitment of the Ccr4-not Complex by Drosophila and Vertebrate Nanos Embo J., 35, 2016
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5FU7
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![BU of 5fu7 by Molmil](/molmil-images/mine/5fu7) | drosophila nanos NBR peptide bound to the NOT module of the human CCR4-NOT complex | Descriptor: | CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 2, CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 3, ... | Authors: | Raisch, T, Bhandari, D, Sabath, K, Helms, S, Valkov, E, Weichenrieder, O, Izaurralde, E. | Deposit date: | 2016-01-21 | Release date: | 2016-03-23 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Distinct Modes of Recruitment of the Ccr4-not Complex by Drosophila and Vertebrate Nanos Embo J., 35, 2016
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7P08
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![BU of 7p08 by Molmil](/molmil-images/mine/7p08) | |