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3D7A
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BU of 3d7a by Molmil
Crystal structure of DUF54 family protein PH1010 from hyperthermophilic archaea Pyrococcus horikoshii OT3
Descriptor: UPF0201 protein PH1010
Authors:Shirokane, M, Miyazono, K.I, Sawano, Y, Tanokura, M.
Deposit date:2008-05-20
Release date:2008-12-09
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the DUF54 family protein PH1010 from hyperthermophilic archaea Pyrococcus horikoshii OT3.
Proteins, 74, 2008
6NEO
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BU of 6neo by Molmil
Crystal structure of PprA filament from Deinococcus radiodurans
Descriptor: DNA repair protein PprA
Authors:Szabla, R, Junop, M.S, Rok, M.
Deposit date:2018-12-18
Release date:2019-02-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (5.94 Å)
Cite:Crystal structure of PprA filament from Deinococcus radiodurans
To Be Published
2DPQ
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BU of 2dpq by Molmil
The crystal structures of the calcium-bound con-G and con-T(K7gamma) dimeric peptides demonstrate a novel metal-dependent helix-forming motif
Descriptor: CALCIUM ION, CHLORIDE ION, Conantokin-G
Authors:Cnudde, S.E, Prorok, M, Dai, Q, Castellino, F.J, Geiger, J.H.
Deposit date:2006-05-13
Release date:2007-04-24
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:The crystal structures of the calcium-bound con-G and con-T[K7gamma] dimeric peptides demonstrate a metal-dependent helix-forming motif
J.Am.Chem.Soc., 129, 2007
2DOI
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BU of 2doi by Molmil
The X-ray crystallographic structure of the angiogenesis inhibitor, angiostatin, bound to a peptide from the group A streptococcus protein PAM
Descriptor: Angiostatin, Plasminogen-binding group A streptococcal M-like protein PAM
Authors:Cnudde, S.E, Prorok, M, Castellino, F.J, Geiger, J.H.
Deposit date:2006-04-29
Release date:2006-12-05
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:X-ray crystallographic structure of the angiogenesis inhibitor, angiostatin, bound to a peptide from the group A streptococcal surface protein PAM
Biochemistry, 45, 2006
2DOH
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BU of 2doh by Molmil
The X-ray crystallographic structure of the angiogenesis inhibitor, angiostatin, bound a to a peptide from the group A streptococcal surface protein PAM
Descriptor: 1,4-DIETHYLENE DIOXIDE, Angiostatin, Plasminogen-binding group A streptococcal M-like protein PAM
Authors:Cnudde, S.E, Prorok, M, Castellino, F.J, Geiger, J.H.
Deposit date:2006-04-29
Release date:2006-12-05
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:X-ray crystallographic structure of the angiogenesis inhibitor, angiostatin, bound to a peptide from the group A streptococcal surface protein PAM
Biochemistry, 45, 2006
2DPR
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BU of 2dpr by Molmil
The crystal structures of the calcium-bound con-G and con-T(K7Glu) dimeric peptides demonstrate a novel metal-dependent helix-forming motif
Descriptor: CALCIUM ION, Conantokin-T
Authors:Cnudde, S.E, Prorok, M, Dai, Q, Castellino, F.J, Geiger, J.H.
Deposit date:2006-05-13
Release date:2007-04-24
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The crystal structures of the calcium-bound con-G and con-T[K7gamma] dimeric peptides demonstrate a metal-dependent helix-forming motif
J.Am.Chem.Soc., 129, 2007
2KJ4
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BU of 2kj4 by Molmil
Solution structure of the complex of VEK-30 and plasminogen kringle 2
Descriptor: VEK-30, plasminogen
Authors:Wang, M, Zajicek, J, Prorok, M, Castellin, F.J.
Deposit date:2009-05-21
Release date:2009-10-20
Last modified:2024-10-16
Method:SOLUTION NMR
Cite:Solution structure of the complex of VEK-30 and plasminogen kringle 2.
J.Struct.Biol., 169, 2010
2GMT
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BU of 2gmt by Molmil
THREE-DIMENSIONAL STRUCTURE OF CHYMOTRYPSIN INACTIVATED WITH (2S) N-ACETYL-L-ALANYL-L-PHENYLALANYL-CHLOROETHYL KETONE: IMPLICATIONS FOR THE MECHANISM OF INACTIVATION OF SERINE PROTEASES BY CHLOROKETONES
Descriptor: (2S) N-ACETYL-L-ALANYL-ALPHAL-PHENYLALANYL-CHLOROETHYLKETONE, GAMMA-CHYMOTRYPSIN
Authors:Kreutter, K, Steinmetz, A.C.U, Liang, T.-C, Prorok, M, Abeles, R, Ringe, D.
Deposit date:1994-09-07
Release date:1994-11-01
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Three-dimensional structure of chymotrypsin inactivated with (2S)-N-acetyl-L-alanyl-L-phenylalanyl alpha-chloroethane: implications for the mechanism of inactivation of serine proteases by chloroketones.
Biochemistry, 33, 1994
6MC8
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BU of 6mc8 by Molmil
Crystal structure of PprA dimer from Deinococcus deserti
Descriptor: DNA repair protein PprA
Authors:Szabla, R, Junop, M.S, Rok, M.
Deposit date:2018-08-30
Release date:2018-09-19
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of PprA from Deinococcus radiodurans
To Be Published
6O5L
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BU of 6o5l by Molmil
Crystal structure of PprA filament from Deinococcus peraridilitoris
Descriptor: PprA
Authors:Szabla, R, Junop, M.S, Rok, M.
Deposit date:2019-03-04
Release date:2019-03-13
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Crystal structure of PprA filament from Deinococcus peraridilitoris
To Be Published
6KLF
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BU of 6klf by Molmil
Crystal structure of branching enzyme D434A mutant from Cyanothece sp. ATCC 51142
Descriptor: 1,4-alpha-glucan branching enzyme GlgB, GLYCEROL, MAGNESIUM ION
Authors:Suzuki, R, Suzuki, E.
Deposit date:2019-07-30
Release date:2020-08-05
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Cyanobacterial branching enzymes bind to alpha-glucan via surface binding sites
Arch.Biochem.Biophys., 702, 2021
7R08
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BU of 7r08 by Molmil
Abortive infection DNA polymerase Abi-P2
Descriptor: Reverse transcriptase
Authors:Gapinska, M.A, Figiel, M, Czarnocki Cieciura, M, Nowotny, M, Zajko, W.
Deposit date:2022-02-01
Release date:2022-09-07
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Mechanism of protein-primed template-independent DNA synthesis by Abi polymerases.
Nucleic Acids Res., 50, 2022
7R06
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BU of 7r06 by Molmil
Abortive infection DNA polymerase AbiK from Lactococcus lactis
Descriptor: AbiK, DNA (5'-D(*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*C)-3')
Authors:Figiel, M, Nowotny, M, Gapinska, M, Czarnocki-Cieciura, M, Zajko, W.
Deposit date:2022-02-01
Release date:2022-09-07
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (2.27 Å)
Cite:Mechanism of protein-primed template-independent DNA synthesis by Abi polymerases.
Nucleic Acids Res., 50, 2022
7R07
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BU of 7r07 by Molmil
Abortive infection DNA polymerase AbiK from Lactococcus lactis
Descriptor: AbiK, DNA (5'-D(*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*C)-3'), MAGNESIUM ION
Authors:Figiel, M, Gapinska, M, Czarnocki-Cieciura, M, Zajko, W, Nowotny, M.
Deposit date:2022-02-01
Release date:2022-09-07
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Mechanism of protein-primed template-independent DNA synthesis by Abi polymerases.
Nucleic Acids Res., 50, 2022
7Z0Z
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BU of 7z0z by Molmil
Abortive infection DNA polymerase AbiK from Lactococcus lactis, Y44F variant
Descriptor: AbiK
Authors:Figiel, M, Gapinska, M, Czarnocki-Cieciura, M, Zajko, W, Nowotny, M.
Deposit date:2022-02-24
Release date:2022-09-07
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.68 Å)
Cite:Mechanism of protein-primed template-independent DNA synthesis by Abi polymerases.
Nucleic Acids Res., 50, 2022
5MP4
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BU of 5mp4 by Molmil
The structure of Pst2p from Saccharomyces cerevisiae
Descriptor: PHOSPHATE ION, Protoplast secreted protein 2
Authors:Hromic, A, Gruber, K.
Deposit date:2016-12-15
Release date:2017-05-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Structure, biochemical and kinetic properties of recombinant Pst2p from Saccharomyces cerevisiae, a FMN-dependent NAD(P)H:quinone oxidoreductase.
Biochim. Biophys. Acta, 1865, 2017
7OGJ
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BU of 7ogj by Molmil
Crystal structure of human METTL1 in complex with SAH
Descriptor: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Nai, F, Bedi, R.K, Caflisch, A.
Deposit date:2021-05-06
Release date:2021-05-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Small-Molecule Inhibitors of the m7G-RNA Writer METTL1
Acs Bio Med Chem Au, 2023
8Q2W
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BU of 8q2w by Molmil
Crystal structure of YTHDC1 in complex with Compound 8 (CS_01)
Descriptor: 2-chloranyl-9-(cyclohexylmethyl)-~{N}-methyl-purin-6-amine, SULFATE ION, YTH domain-containing protein 1
Authors:Bedi, R.K, Zalesak, F, Caflisch, A.
Deposit date:2023-08-03
Release date:2023-12-06
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:Structure-Based Design of a Potent and Selective YTHDC1 Ligand.
J.Med.Chem., 67, 2024
8Q2Q
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BU of 8q2q by Molmil
Crystal structure of YTHDC1 in complex with Compound 2b (YL_32)
Descriptor: 2-chloranyl-~{N},9-dimethyl-purin-6-amine, SULFATE ION, YTH domain-containing protein 1
Authors:Bedi, R.K, Li, Y, Caflisch, A.
Deposit date:2023-08-03
Release date:2023-12-06
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structure-Based Design of a Potent and Selective YTHDC1 Ligand.
J.Med.Chem., 67, 2024
8Q32
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BU of 8q32 by Molmil
Crystal structure of YTHDC1 in complex with Compound 13 (ZA_364)
Descriptor: SULFATE ION, YTH domain-containing protein 1, ~{N}-[2-[[2-chloranyl-6-(methylamino)purin-9-yl]methyl]phenyl]methanesulfonamide
Authors:Bedi, R.K, Zalesak, F, Caflisch, A.
Deposit date:2023-08-03
Release date:2023-12-06
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Structure-Based Design of a Potent and Selective YTHDC1 Ligand.
J.Med.Chem., 67, 2024
8Q4U
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BU of 8q4u by Molmil
Crystal structure of YTHDC1 in complex with Compound 36 (ZA_540b)
Descriptor: 9-[(3-chlorophenyl)methyl]-2-fluoranyl-~{N}-methyl-purin-6-amine, SULFATE ION, YTH domain-containing protein 1
Authors:Bedi, R.K, Zalesak, F, Caflisch, A.
Deposit date:2023-08-07
Release date:2023-12-06
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:Structure-Based Design of a Potent and Selective YTHDC1 Ligand.
J.Med.Chem., 67, 2024
8Q4R
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BU of 8q4r by Molmil
Crystal structure of YTHDC1 in complex with Compound 30 (ZA_326)
Descriptor: SULFATE ION, YTH domain-containing protein 1, [4-[[2-chloranyl-6-(methylamino)purin-9-yl]methyl]phenyl]methanol
Authors:Bedi, R.K, Zalesak, F, Caflisch, A.
Deposit date:2023-08-07
Release date:2023-12-06
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Structure-Based Design of a Potent and Selective YTHDC1 Ligand.
J.Med.Chem., 67, 2024
8Q2X
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BU of 8q2x by Molmil
Crystal structure of YTHDC1 in complex with Compound 10 (ZA_294)
Descriptor: 3-[2-chloranyl-6-(methylamino)purin-9-yl]benzoic acid, SULFATE ION, YTH domain-containing protein 1
Authors:Bedi, R.K, Zalesak, F, Caflisch, A.
Deposit date:2023-08-03
Release date:2023-12-06
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure-Based Design of a Potent and Selective YTHDC1 Ligand.
J.Med.Chem., 67, 2024
8Q38
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BU of 8q38 by Molmil
Crystal structure of YTHDC1 in complex with Compound 19 (ZA_347)
Descriptor: SULFATE ION, YTH domain-containing protein 1, methyl 3-[[2-chloranyl-6-(methylamino)purin-9-yl]methyl]benzoate
Authors:Bedi, R.K, Zalesak, F, Caflisch, A.
Deposit date:2023-08-03
Release date:2023-12-06
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Structure-Based Design of a Potent and Selective YTHDC1 Ligand.
J.Med.Chem., 67, 2024
8Q4Q
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BU of 8q4q by Molmil
Crystal structure of YTHDC1 in complex with Compound 29 (ZA_337)
Descriptor: 4-[[2-chloranyl-6-(methylamino)purin-9-yl]methyl]benzoic acid, SULFATE ION, YTH domain-containing protein 1
Authors:Bedi, R.K, Zalesak, F, Caflisch, A.
Deposit date:2023-08-07
Release date:2023-12-06
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structure-Based Design of a Potent and Selective YTHDC1 Ligand.
J.Med.Chem., 67, 2024

 

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數據於2024-11-06公開中

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