8DHU
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![BU of 8dhu by Molmil](/molmil-images/mine/8dhu) | Crystal structure of LARP-DM15 from Drosophila melanogaster bound to m7GpppC | Descriptor: | La-related protein 1, MAGNESIUM ION, [[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-7-methyl-6-oxidanylidene-1~{H}-purin-9-ium-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [[(2~{R},3~{S},4~{R},5~{R})-5-(4-azanyl-2-oxidanylidene-pyrimidin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] hydrogen phosphate | Authors: | Nguyen, E, Berman, A.J. | Deposit date: | 2022-06-28 | Release date: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.295 Å) | Cite: | Comparative analysis of the LARP1 C-terminal DM15 region through Coelomate evolution To Be Published
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8DIO
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![BU of 8dio by Molmil](/molmil-images/mine/8dio) | |
5U7E
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![BU of 5u7e by Molmil](/molmil-images/mine/5u7e) | |
5U7H
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![BU of 5u7h by Molmil](/molmil-images/mine/5u7h) | |
5U7F
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![BU of 5u7f by Molmil](/molmil-images/mine/5u7f) | |
4XAV
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![BU of 4xav by Molmil](/molmil-images/mine/4xav) | Crystal structure of olfactomedin domain from gliomedin | Descriptor: | GLYCEROL, Gliomedin, PHOSPHATE ION, ... | Authors: | Hill, S.E, Nguyen, E, Lieberman, R.L. | Deposit date: | 2014-12-15 | Release date: | 2015-07-15 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.052 Å) | Cite: | Molecular Details of Olfactomedin Domains Provide Pathway to Structure-Function Studies. Plos One, 10, 2015
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4XAT
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![BU of 4xat by Molmil](/molmil-images/mine/4xat) | Crystal structure of the olfactomedin domain from noelin/pancortin/olfactomedin-1 | Descriptor: | CALCIUM ION, GLYCEROL, Noelin, ... | Authors: | Hill, S.E, Nguyen, E, Lieberman, R.L. | Deposit date: | 2014-12-15 | Release date: | 2015-07-15 | Last modified: | 2022-03-30 | Method: | X-RAY DIFFRACTION (2.113 Å) | Cite: | Molecular Details of Olfactomedin Domains Provide Pathway to Structure-Function Studies. Plos One, 10, 2015
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6OKE
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![BU of 6oke by Molmil](/molmil-images/mine/6oke) | |
6OKD
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![BU of 6okd by Molmil](/molmil-images/mine/6okd) | Crystal Structure of human transferrin receptor in complex with a cystine-dense peptide | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... | Authors: | Finton, K.A.K, Rupert, P.B, Strong, R.K. | Deposit date: | 2019-04-12 | Release date: | 2020-04-15 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | A TfR-Binding Cystine-Dense Peptide Promotes Blood-Brain Barrier Penetration of Bioactive Molecules. J.Mol.Biol., 432, 2020
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5RG8
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![BU of 5rg8 by Molmil](/molmil-images/mine/5rg8) | Crystal Structure of Kemp Eliminase HG3.17 in unbound state, 277K | Descriptor: | ACETATE ION, Kemp Eliminase HG3 | Authors: | Broom, A, Rakotoharisoa, R.V, Thompson, M.C, Fraser, J.S, Chica, R.A. | Deposit date: | 2020-03-19 | Release date: | 2020-07-22 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Ensemble-based enzyme design can recapitulate the effects of laboratory directed evolution in silico. Nat Commun, 11, 2020
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5RG7
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![BU of 5rg7 by Molmil](/molmil-images/mine/5rg7) | Crystal Structure of Kemp Eliminase HG3.14 in unbound state, 277K | Descriptor: | Kemp Eliminase HG3, SULFATE ION | Authors: | Broom, A, Rakotoharisoa, R.V, Thompson, M.C, Fraser, J.S, Chica, R.A. | Deposit date: | 2020-03-19 | Release date: | 2020-07-22 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | Ensemble-based enzyme design can recapitulate the effects of laboratory directed evolution in silico. Nat Commun, 11, 2020
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5VR2
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![BU of 5vr2 by Molmil](/molmil-images/mine/5vr2) | |
5RGE
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![BU of 5rge by Molmil](/molmil-images/mine/5rge) | Crystal Structure of Kemp Eliminase HG3.17 with bound transition state analog, 277K | Descriptor: | 6-NITROBENZOTRIAZOLE, Kemp Eliminase HG3 | Authors: | Broom, A, Rakotoharisoa, R.V, Thompson, M.C, Fraser, J.S, Chica, R.A. | Deposit date: | 2020-03-19 | Release date: | 2020-07-22 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Ensemble-based enzyme design can recapitulate the effects of laboratory directed evolution in silico. Nat Commun, 11, 2020
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5RG9
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![BU of 5rg9 by Molmil](/molmil-images/mine/5rg9) | Crystal Structure of Kemp Eliminase HG4 in unbound state, 277K | Descriptor: | ACETATE ION, Kemp Eliminase HG4, SULFATE ION | Authors: | Broom, A, Rakotoharisoa, R.V, Thompson, M.C, Fraser, J.S, Chica, R.A. | Deposit date: | 2020-03-19 | Release date: | 2020-07-22 | Last modified: | 2021-05-12 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | Ensemble-based enzyme design can recapitulate the effects of laboratory directed evolution in silico. Nat Commun, 11, 2020
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5RGF
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![BU of 5rgf by Molmil](/molmil-images/mine/5rgf) | Crystal Structure of Kemp Eliminase HG4 with bound transition state analogue, 277K | Descriptor: | 6-NITROBENZOTRIAZOLE, Kemp Eliminase HG3, SULFATE ION | Authors: | Broom, A, Rakotoharisoa, R.V, Thompson, M.C, Fraser, J.S, Chica, R.A. | Deposit date: | 2020-03-19 | Release date: | 2020-07-22 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.46 Å) | Cite: | Ensemble-based enzyme design can recapitulate the effects of laboratory directed evolution in silico. Nat Commun, 11, 2020
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5RGC
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![BU of 5rgc by Molmil](/molmil-images/mine/5rgc) | Crystal Structure of Kemp Eliminase HG3.7 with bound transition state analogue, 277K | Descriptor: | 6-NITROBENZOTRIAZOLE, Kemp Eliminase HG3, SULFATE ION | Authors: | Broom, A, Rakotoharisoa, R.V, Thompson, M.C, Fraser, J.S, Chica, R.A. | Deposit date: | 2020-03-19 | Release date: | 2020-07-22 | Last modified: | 2021-05-12 | Method: | X-RAY DIFFRACTION (1.39 Å) | Cite: | Ensemble-based enzyme design can recapitulate the effects of laboratory directed evolution in silico. Nat Commun, 11, 2020
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5RGA
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![BU of 5rga by Molmil](/molmil-images/mine/5rga) | Crystal Structure of Kemp Eliminase HG3 with bound transition state analogue, 277K | Descriptor: | 6-NITROBENZOTRIAZOLE, Kemp Eliminase HG3, SULFATE ION | Authors: | Broom, A, Rakotoharisoa, R.V, Thompson, M.C, Fraser, J.S, Chica, R.A. | Deposit date: | 2020-03-19 | Release date: | 2020-07-22 | Last modified: | 2021-05-12 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Ensemble-based enzyme design can recapitulate the effects of laboratory directed evolution in silico. Nat Commun, 11, 2020
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5RGD
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![BU of 5rgd by Molmil](/molmil-images/mine/5rgd) | Crystal Structure of Kemp Eliminase HG3.14 with bound transition state analogue, 277K | Descriptor: | 6-NITROBENZOTRIAZOLE, Kemp Eliminase HG3.14, SULFATE ION | Authors: | Broom, A, Rakotoharisoa, R.V, Thompson, M.C, Fraser, J.S, Chica, R.A. | Deposit date: | 2020-03-19 | Release date: | 2020-07-22 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Ensemble-based enzyme design can recapitulate the effects of laboratory directed evolution in silico. Nat Commun, 11, 2020
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5RG4
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![BU of 5rg4 by Molmil](/molmil-images/mine/5rg4) | Crystal Structure of Kemp Eliminase HG3 in unbound state, 277K | Descriptor: | ACETATE ION, Kemp Eliminase HG3, SULFATE ION | Authors: | Broom, A, Rakotoharisoa, R.V, Thompson, M.C, Fraser, J.S, Chica, R.A. | Deposit date: | 2020-03-19 | Release date: | 2020-07-22 | Last modified: | 2021-05-12 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Ensemble-based enzyme design can recapitulate the effects of laboratory directed evolution in silico. Nat Commun, 11, 2020
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5RG6
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![BU of 5rg6 by Molmil](/molmil-images/mine/5rg6) | Crystal Structure of Kemp Eliminase HG3.7 in unbound state, 277K | Descriptor: | Kemp Eliminase HG3, SULFATE ION | Authors: | Broom, A, Rakotoharisoa, R.V, Thompson, M.C, Fraser, J.S, Chica, R.A. | Deposit date: | 2020-03-19 | Release date: | 2020-07-22 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Ensemble-based enzyme design can recapitulate the effects of laboratory directed evolution in silico. Nat Commun, 11, 2020
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5RG5
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![BU of 5rg5 by Molmil](/molmil-images/mine/5rg5) | Crystal Structure of Kemp Eliminase HG3.3b in unbound state, 277K | Descriptor: | ACETATE ION, Kemp Eliminase HG3, SULFATE ION | Authors: | Broom, A, Rakotoharisoa, R.V, Thompson, M.C, Fraser, J.S, Chica, R.A. | Deposit date: | 2020-03-19 | Release date: | 2020-07-22 | Last modified: | 2021-05-12 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | Ensemble-based enzyme design can recapitulate the effects of laboratory directed evolution in silico. Nat Commun, 11, 2020
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5RGB
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![BU of 5rgb by Molmil](/molmil-images/mine/5rgb) | Crystal Structure of Kemp Eliminase HG3.3b with bound transition state analogue, 277K | Descriptor: | 6-NITROBENZOTRIAZOLE, Kemp Eliminase HG3.3b, SULFATE ION | Authors: | Broom, A, Rakotoharisoa, R.V, Thompson, M.C, Fraser, J.S, Chica, R.A. | Deposit date: | 2020-03-19 | Release date: | 2020-07-22 | Last modified: | 2021-05-12 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | Ensemble-based enzyme design can recapitulate the effects of laboratory directed evolution in silico. Nat Commun, 11, 2020
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4WXS
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![BU of 4wxs by Molmil](/molmil-images/mine/4wxs) | Crystal Structure of the E396D SNP Variant of the Myocilin Olfactomedin Domain | Descriptor: | CALCIUM ION, GLYCEROL, HEXAETHYLENE GLYCOL, ... | Authors: | Donegan, R.K, Freeman, D.M, Lieberman, R.L. | Deposit date: | 2014-11-14 | Release date: | 2015-04-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural basis for misfolding in myocilin-associated glaucoma. Hum.Mol.Genet., 24, 2015
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4WXU
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![BU of 4wxu by Molmil](/molmil-images/mine/4wxu) | Crystal Structure of the Selenomthionine Incorporated Myocilin Olfactomedin Domain E396D Variant. | Descriptor: | CALCIUM ION, GLYCEROL, HEXAETHYLENE GLYCOL, ... | Authors: | Donegan, R.K, Freeman, D.M, Lieberman, R.L. | Deposit date: | 2014-11-14 | Release date: | 2015-04-01 | Method: | X-RAY DIFFRACTION (2.092 Å) | Cite: | Structural basis for misfolding in myocilin-associated glaucoma. Hum.Mol.Genet., 24, 2015
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4WXQ
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![BU of 4wxq by Molmil](/molmil-images/mine/4wxq) | Crystal Structure of the Myocilin Olfactomedin Domain | Descriptor: | CALCIUM ION, HEXAETHYLENE GLYCOL, Myocilin, ... | Authors: | Orwig, S.D, Turnage, K.C, Donegan, R.K, Lieberman, R.L. | Deposit date: | 2014-11-14 | Release date: | 2015-04-01 | Last modified: | 2017-09-06 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structural basis for misfolding in myocilin-associated glaucoma. Hum.Mol.Genet., 24, 2015
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