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Structure of angiotensin II type I receptor (AT1R) nanobody antagonist AT118i4h32 G26D T57I variant
Descriptor:	CITRIC ACID, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:	Nemeth, G.R, Skiba, M.A, Kruse, A.C.
Deposit date:	2021-12-15
Release date:	2022-12-07
Last modified:	2023-10-25
Method:	X-RAY DIFFRACTION (1.6 Å)
Cite:	An in silico method to assess antibody fragment polyreactivity. Nat Commun, 13, 2022

Structure of AT118-L Nanobody Antagonist in Complex with the Angiotensin II Type I Receptor and Losartan
Descriptor:	AT118-L Nanobody, BAG2 Anti-BRIL Fab Heavy Chain, BAG2 Anti-BRIL Fab Light Chain, ...
Authors:	Skiba, M.A, Kruse, A.C.
Deposit date:	2023-07-13
Release date:	2024-05-22
Last modified:	2024-05-29
Method:	ELECTRON MICROSCOPY (3.3 Å)
Cite:	Antibodies expand the scope of angiotensin receptor pharmacology. Nat.Chem.Biol., 2024

Structure of AT118-H Nanobody Antagonist in Complex with the Angiotensin II Type I Receptor
Descriptor:	AT118-H nanobody, Type-1 angiotensin II receptor, Soluble cytochrome b562 complex, ...
Authors:	Skiba, M.A, Kruse, A.C.
Deposit date:	2023-07-13
Release date:	2024-05-22
Last modified:	2024-05-29
Method:	ELECTRON MICROSCOPY (3 Å)
Cite:	Antibodies expand the scope of angiotensin receptor pharmacology. Nat.Chem.Biol., 2024

Structure of angiotensin II type I receptor (AT1R) nanobody antagonist AT118i4h32
Descriptor:	CITRATE ANION, Nanobody AT118i4h32
Authors:	Skiba, M.A, Kruse, A.C.
Deposit date:	2021-12-15
Release date:	2022-12-07
Last modified:	2023-10-25
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	An in silico method to assess antibody fragment polyreactivity. Nat Commun, 13, 2022