6LVW
| |
9FH9
| Structure of CyclinB1 N-terminus bound to the NCP | Descriptor: | DNA (145-MER), G2/mitotic-specific cyclin-B1, Histone H2A type 3, ... | Authors: | Young, R.V.C, Muhammad, R, Alfieri, C. | Deposit date: | 2024-05-27 | Release date: | 2024-07-24 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Spatial control of the APC/C ensures the rapid degradation of cyclin B1. Embo J., 43, 2024
|
|
9FGQ
| Structure of human APC3loop 375-381 bound to the NCP | Descriptor: | Cell division cycle protein 27 homolog, DNA (131-MER), DNA (132-MER), ... | Authors: | Young, R.V.C, Muhammad, R, Alfieri, C. | Deposit date: | 2024-05-24 | Release date: | 2024-07-24 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Spatial control of the APC/C ensures the rapid degradation of cyclin B1. Embo J., 43, 2024
|
|
5DNM
| Nucleosome core particle containing adducts of ruthenium(II)-toluene PTA complex | Descriptor: | DNA (145-MER), Histone H2A, Histone H2B 1.1, ... | Authors: | Adhireksan, Z, Muhammad, R, Davey, C.A. | Deposit date: | 2015-09-10 | Release date: | 2016-09-14 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.81 Å) | Cite: | Allosteric cross-talk in chromatin can mediate drug-drug synergy Nat Commun, 8, 2017
|
|
3MGR
| Binding of Rubidium ions to the Nucleosome Core Particle | Descriptor: | CHLORIDE ION, DNA (147-MER), Histone H2A, ... | Authors: | Mohideen, K, Muhammad, R, Davey, C.A. | Deposit date: | 2010-04-07 | Release date: | 2010-06-16 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Perturbations in nucleosome structure from heavy metal association. Nucleic Acids Res., 38, 2010
|
|
3MGQ
| Binding of Nickel ions to the Nucleosome Core Particle | Descriptor: | CHLORIDE ION, DNA (147-MER), Histone H2A, ... | Authors: | Mohideen, K, Muhammad, R, Davey, C.A. | Deposit date: | 2010-04-07 | Release date: | 2010-06-16 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Perturbations in nucleosome structure from heavy metal association. Nucleic Acids Res., 38, 2010
|
|
3MGP
| Binding of Cobalt ions to the Nucleosome Core Particle | Descriptor: | CHLORIDE ION, COBALT (II) ION, DNA (147-MER), ... | Authors: | Mohideen, K, Muhammad, R, Davey, C.A. | Deposit date: | 2010-04-07 | Release date: | 2010-06-16 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.44 Å) | Cite: | Perturbations in nucleosome structure from heavy metal association. Nucleic Acids Res., 38, 2010
|
|
3MGS
| |
8BPA
| Cryo-EM structure of the human SIN3B histone deacetylase complex at 3.7 Angstrom | Descriptor: | CALCIUM ION, Histone deacetylase 2, Isoform 2 of Paired amphipathic helix protein Sin3b, ... | Authors: | Wan, M.S.M, Muhammad, R, Koliopolous, M.G, Alfieri, C. | Deposit date: | 2022-11-16 | Release date: | 2023-05-10 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Mechanism of assembly, activation and lysine selection by the SIN3B histone deacetylase complex. Nat Commun, 14, 2023
|
|
8BPB
| Cryo-EM structure of the human SIN3B histone deacetylase core complex at 2.8 Angstrom | Descriptor: | ACETATE ION, CALCIUM ION, Histone deacetylase 2, ... | Authors: | Wan, M.S.M, Muhammad, R, Koliopolous, M.G, Alfieri, C. | Deposit date: | 2022-11-16 | Release date: | 2023-05-10 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Mechanism of assembly, activation and lysine selection by the SIN3B histone deacetylase complex. Nat Commun, 14, 2023
|
|
8BPC
| Cryo-EM structure of the human SIN3B histone deacetylase core complex with SAHA at 2.8 Angstrom | Descriptor: | CALCIUM ION, Histone deacetylase 2, Isoform 2 of Paired amphipathic helix protein Sin3b, ... | Authors: | Wan, M.S.M, Muhammad, R, Koliopolous, M.G, Alfieri, C. | Deposit date: | 2022-11-16 | Release date: | 2023-05-10 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Mechanism of assembly, activation and lysine selection by the SIN3B histone deacetylase complex. Nat Commun, 14, 2023
|
|
8C60
| Cryo-EM structure of the human SIN3B full-length complex at 3.4 Angstrom resolution | Descriptor: | CALCIUM ION, Histone deacetylase 2, Isoform 2 of Paired amphipathic helix protein Sin3b, ... | Authors: | Alfieri, C, Wan, S.M, Muhammad, R. | Deposit date: | 2023-01-10 | Release date: | 2023-05-10 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Mechanism of assembly, activation and lysine selection by the SIN3B histone deacetylase complex. Nat Commun, 14, 2023
|
|
7R1D
| Structure of MuvB complex | Descriptor: | Histone-binding protein RBBP4, Protein lin-37 homolog, Protein lin-9 homolog | Authors: | Koliopoulos, M.G, Alfieri, C. | Deposit date: | 2022-02-02 | Release date: | 2022-08-10 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure of a nucleosome-bound MuvB transcription factor complex reveals DNA remodelling. Nat Commun, 13, 2022
|
|
5DNN
| Nucleosome core particle containing adducts of gold(I)-triethylphosphane and ruthenium(II)-toluene PTA complexes | Descriptor: | DNA (145-MER), Histone H2A, Histone H2B 1.1, ... | Authors: | Adhireksan, Z, Ma, Z, Davey, C.A. | Deposit date: | 2015-09-10 | Release date: | 2016-09-14 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Allosteric cross-talk in chromatin can mediate drug-drug synergy Nat Commun, 8, 2017
|
|