2BE6
| 2.0 A crystal structure of the CaV1.2 IQ domain-Ca/CaM complex | Descriptor: | CALCIUM ION, Calmodulin 2, NICKEL (II) ION, ... | Authors: | Van Petegem, F, Chatelain, F.C, Minor Jr, D.L. | Deposit date: | 2005-10-23 | Release date: | 2005-11-15 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Insights into voltage-gated calcium channel regulation from the structure of the Ca(V)1.2 IQ domain-Ca(2+)/calmodulin complex Nat.Struct.Mol.Biol., 12, 2005
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2I2R
| Crystal structure of the KChIP1/Kv4.3 T1 complex | Descriptor: | CALCIUM ION, Kv channel-interacting protein 1, Potassium voltage-gated channel subfamily D member 3, ... | Authors: | Findeisen, F, Pioletti, M, Minor Jr, D.L. | Deposit date: | 2006-08-16 | Release date: | 2006-10-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.35 Å) | Cite: | Three-dimensional structure of the KChIP1-Kv4.3 T1 complex reveals a cross-shaped octamer Nat.Struct.Mol.Biol., 13, 2006
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1N0Q
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1N0R
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1QDV
| N-TERMINAL DOMAIN, VOLTAGE-GATED POTASSIUM CHANNEL KV1.2 RESIDUES 33-131 | Descriptor: | KV1.2 VOLTAGE-GATED POTASSIUM CHANNEL | Authors: | Minor Jr, D.L, Lin, Y.-F, Mobley, B.C, Yu, M, Jan, Y.N, Jan, L.Y, Berger, J.M. | Deposit date: | 1999-07-10 | Release date: | 2000-09-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The polar T1 interface is linked to conformational changes that open the voltage-gated potassium channel. Cell(Cambridge,Mass.), 102, 2000
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1QDW
| N-TERMINAL DOMAIN, VOLTAGE-GATED POTASSIUM CHANNEL KV1.2 RESIDUES 33-119 | Descriptor: | KV1.2 VOLTAGE-GATED POTASSIUM CHANNEL | Authors: | Minor Jr, D.L, Lin, Y.-F, Mobley, B.C, Avelar, A, Jan, Y.N, Jan, L.Y, Berger, J.M. | Deposit date: | 1999-07-10 | Release date: | 2000-09-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The polar T1 interface is linked to conformational changes that open the voltage-gated potassium channel. Cell(Cambridge,Mass.), 102, 2000
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1DSX
| KV1.2 T1 DOMAIN, RESIDUES 33-119, T46V MUTANT | Descriptor: | PROTEIN (KV1.2 VOLTAGE-GATED POTASSIUM CHANNEL) | Authors: | Minor Jr, D.L, Lin, Y.-F, Mobley, B.C, Avelar, A, Jan, Y.N, Jan, L.Y, Berger, J.M. | Deposit date: | 2000-01-10 | Release date: | 2000-09-20 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The polar T1 interface is linked to conformational changes that open the voltage-gated potassium channel. Cell(Cambridge,Mass.), 102, 2000
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8D6G
| Nanorana parkeri saxiphilin | Descriptor: | PENTAETHYLENE GLYCOL, Saxiphilin | Authors: | Zakrzewska, S, Chen, Z, Minor, D.L. | Deposit date: | 2022-06-06 | Release date: | 2022-11-02 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Definition of a saxitoxin (STX) binding code enables discovery and characterization of the anuran saxiphilin family. Proc.Natl.Acad.Sci.USA, 119, 2022
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8D6T
| Rana catesbeiana saxiphilin mutant - Y558I:STX (co-crystal) | Descriptor: | CACODYLATE ION, Saxiphilin, [(3aS,4R,10aS)-2,6-diamino-10,10-dihydroxy-3a,4,9,10-tetrahydro-3H,8H-pyrrolo[1,2-c]purin-4-yl]methyl carbamate | Authors: | Chen, Z, Zakrzewska, S, Minor, D.L. | Deposit date: | 2022-06-06 | Release date: | 2022-11-02 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Definition of a saxitoxin (STX) binding code enables discovery and characterization of the anuran saxiphilin family. Proc.Natl.Acad.Sci.USA, 119, 2022
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8D6P
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8D6O
| Nanorana parkeri saxiphilin:F-STX (soaked) | Descriptor: | (2P)-4-({6-[({[(3aS,4R,7R,10aS)-2,6-diamino-10,10-dihydroxy-3a,4,9,10-tetrahydro-3H,8H-pyrrolo[1,2-c]purin-4-yl]methoxy}carbonyl)amino]hexyl}carbamoyl)-2-{[4aP,9(9a)P]-6-hydroxy-3-oxo-3H-xanthen-9-yl}benzoic acid, PENTAETHYLENE GLYCOL, Saxiphilin | Authors: | Zakrzewska, S, Chen, Z, Minor, D.L. | Deposit date: | 2022-06-06 | Release date: | 2022-11-02 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Definition of a saxitoxin (STX) binding code enables discovery and characterization of the anuran saxiphilin family. Proc.Natl.Acad.Sci.USA, 119, 2022
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8D6Q
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8D6S
| Rana catesbeiana saxiphilin mutant - Y558A:STX (co-crystal) | Descriptor: | Saxiphilin, [(3aS,4R,10aS)-2,6-diamino-10,10-dihydroxy-3a,4,9,10-tetrahydro-3H,8H-pyrrolo[1,2-c]purin-4-yl]methyl carbamate | Authors: | Chen, Z, Zakrzewska, S, Minor, D.L. | Deposit date: | 2022-06-06 | Release date: | 2022-11-02 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Definition of a saxitoxin (STX) binding code enables discovery and characterization of the anuran saxiphilin family. Proc.Natl.Acad.Sci.USA, 119, 2022
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8D6M
| Nanorana parkeri saxiphilin:STX (co-crystal) | Descriptor: | PENTAETHYLENE GLYCOL, Saxiphilin, [(3aS,4R,10aS)-2,6-diamino-10,10-dihydroxy-3a,4,9,10-tetrahydro-3H,8H-pyrrolo[1,2-c]purin-4-yl]methyl carbamate | Authors: | Zakrzewska, S, Chen, Z, Minor, D.L. | Deposit date: | 2022-06-06 | Release date: | 2022-11-02 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Definition of a saxitoxin (STX) binding code enables discovery and characterization of the anuran saxiphilin family. Proc.Natl.Acad.Sci.USA, 119, 2022
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8D6U
| Rana catesbeiana saxiphilin:F-STX (soaked) | Descriptor: | (2P)-4-({6-[({[(3aS,4R,7R,10aS)-2,6-diamino-10,10-dihydroxy-3a,4,9,10-tetrahydro-3H,8H-pyrrolo[1,2-c]purin-4-yl]methoxy}carbonyl)amino]hexyl}carbamoyl)-2-{[4aP,9(9a)P]-6-hydroxy-3-oxo-3H-xanthen-9-yl}benzoic acid, Saxiphilin | Authors: | Chen, Z, Zakrzewska, S, Minor, D.L. | Deposit date: | 2022-06-06 | Release date: | 2022-11-02 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Definition of a saxitoxin (STX) binding code enables discovery and characterization of the anuran saxiphilin family. Proc.Natl.Acad.Sci.USA, 119, 2022
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8DAM
| nbF3:nbE8:CaV beta subunit 1b complex | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Nanobody E8, SULFATE ION, ... | Authors: | Nirwan, N, Minor, D.L. | Deposit date: | 2022-06-13 | Release date: | 2022-12-21 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Selective posttranslational inhibition of Ca V beta 1 -associated voltage-dependent calcium channels with a functionalized nanobody. Nat Commun, 13, 2022
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4GOW
| Crystal Structure of Ca2+/CaM:Kv7.4 (KCNQ4) B helix complex | Descriptor: | CALCIUM ION, Calmodulin, Potassium voltage-gated channel subfamily KQT member 4 | Authors: | Xu, Q, Chang, A, Tolia, A, Minor Jr, D.L. | Deposit date: | 2012-08-20 | Release date: | 2012-12-12 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of a Ca(2+)/CaM:Kv7.4 (KCNQ4) B-helix complex provides insight into M current modulation. J.Mol.Biol., 425, 2013
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7PG8
| NaV_Ae1/Sp1CTD_pore-ANT05 complex | Descriptor: | ANT05 H12 fab fragment, heavy chain, light chain, ... | Authors: | Lolicato, M, Arrigoni, C. | Deposit date: | 2021-08-13 | Release date: | 2022-06-08 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (4.5 Å) | Cite: | Quaternary structure independent folding of voltage-gated ion channel pore domain subunits. Nat.Struct.Mol.Biol., 29, 2022
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7PGF
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7PGG
| NaVAb1p detergent (DM) | Descriptor: | 2-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}ethyl heptadecanoate, Ion transport protein | Authors: | Lolicato, M, Arrigoni, C. | Deposit date: | 2021-08-13 | Release date: | 2022-06-15 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Quaternary structure independent folding of voltage-gated ion channel pore domain subunits. Nat.Struct.Mol.Biol., 29, 2022
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6V36
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6V37
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6V3I
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6V3C
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6W7B
| K2P2.1 (TREK-1), 0 mM K+ | Descriptor: | CADMIUM ION, DECANE, DODECANE, ... | Authors: | Lolicato, M, Minor, D.L. | Deposit date: | 2020-03-19 | Release date: | 2021-01-27 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.88 Å) | Cite: | K 2P channel C-type gating involves asymmetric selectivity filter order-disorder transitions. Sci Adv, 6, 2020
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