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4X34
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BU of 4x34 by Molmil
Crystal structure of the 53BP1 tandem tudor domain in complex with p53K381acK382me2
Descriptor: THR-SER-ARG-HIS-ALY-MLY-LEU-MET-PHE-LYS, Tumor suppressor p53-binding protein 1
Authors:Tong, Q, Kutateladze, T.G.
Deposit date:2014-11-27
Release date:2015-03-04
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:An Acetyl-Methyl Switch Drives a Conformational Change in p53.
Structure, 23, 2015
3C6W
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BU of 3c6w by Molmil
Crystal structure of the ING5 PHD finger in complex with H3K4me3 peptide
Descriptor: H3K4me3 histone peptide, Inhibitor of growth protein 5, ZINC ION
Authors:Champagne, K.S, Pena, P.V, Johnson, K, Kutateladze, T.G.
Deposit date:2008-02-05
Release date:2008-06-03
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The crystal structure of the ING5 PHD finger in complex with an H3K4me3 histone peptide.
Proteins, 72, 2008
8E4V
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BU of 8e4v by Molmil
Solution structure of the WH domain of MORF
Descriptor: Isoform 3 of Histone acetyltransferase KAT6B
Authors:Zhang, Y, Kutateladze, T.G.
Deposit date:2022-08-19
Release date:2023-05-10
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:MORF and MOZ acetyltransferases target unmethylated CpG islands through the winged helix domain.
Nat Commun, 14, 2023
3RCP
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BU of 3rcp by Molmil
Crystal structure of the FAPP1 pleckstrin homology domain
Descriptor: GLYCEROL, Pleckstrin homology domain-containing family A member 3
Authors:Roy, S, He, J, Kutateladze, T.G.
Deposit date:2011-03-31
Release date:2011-04-20
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular Basis of Phosphatidylinositol 4-Phosphate and ARF1 GTPase Recognition by the FAPP1 Pleckstrin Homology (PH) Domain.
J.Biol.Chem., 286, 2011
7K7T
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BU of 7k7t by Molmil
Crystal structure of human MORC4 ATPase-CW in complex with AMPPNP
Descriptor: Isoform 3 of MORC family CW-type zinc finger protein 4, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Klein, B.J, Tencer, A.H, Kutateladze, T.G.
Deposit date:2020-09-24
Release date:2020-11-11
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.94 Å)
Cite:Molecular mechanism of the MORC4 ATPase activation.
Nat Commun, 11, 2020
6AXJ
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BU of 6axj by Molmil
Crystal structure of the Yaf9 YEATS domain bound to H3K27ac
Descriptor: ALY-SER-ALA-PRO-ALA, GLYCEROL, Protein AF-9 homolog, ...
Authors:Klein, B.J, Kutateladze, T.G.
Deposit date:2017-09-06
Release date:2017-11-22
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.379 Å)
Cite:Yaf9 subunit of the NuA4 and SWR1 complexes targets histone H3K27ac through its YEATS domain.
Nucleic Acids Res., 46, 2018
3MDF
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BU of 3mdf by Molmil
Crystal structure of the RRM domain of Cyclophilin 33
Descriptor: Peptidyl-prolyl cis-trans isomerase E
Authors:Hom, R.A, Chang, P.Y, Roy, S, Mussleman, C.A, Glass, K.C, Seleznevia, A.I, Gozani, O, Ismagilov, R.F, Cleary, M.L, Kutateladze, T.G.
Deposit date:2010-03-30
Release date:2010-05-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Molecular mechanism of MLL PHD3 and RNA recognition by the Cyp33 RRM domain.
J.Mol.Biol., 400, 2010
8U77
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BU of 8u77 by Molmil
Crystal structure of Taf14 in complex with Yng1
Descriptor: Protein YNG1, Transcription initiation factor TFIID subunit 14
Authors:Nguyen, M.C, Wei, P.C, Zhang, G.Y, Kutateladze, T.G.
Deposit date:2023-09-14
Release date:2024-08-21
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Molecular insight into interactions between the Taf14, Yng1 and Sas3 subunits of the NuA3 complex.
Nat Commun, 15, 2024
8U2Y
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BU of 8u2y by Molmil
Solution structure of the PHD6 finger of MLL4 bound to TET3
Descriptor: Histone-lysine N-methyltransferase 2D, Methylcytosine dioxygenase TET3, ZINC ION
Authors:Mohid, S.A, Zandian, M, Zhang, Y, Kutateladze, T.G.
Deposit date:2023-09-06
Release date:2024-06-19
Method:SOLUTION NMR
Cite:MLL4 binds TET3.
Structure, 32, 2024
4HCZ
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BU of 4hcz by Molmil
PHF1 Tudor in complex with H3K36me3
Descriptor: H3L-like histone, PHD finger protein 1
Authors:Musselman, C.A, Roy, S, Nunez, J, Kutateladze, T.G.
Deposit date:2012-10-01
Release date:2012-11-14
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Molecular basis for H3K36me3 recognition by the Tudor domain of PHF1.
Nat.Struct.Mol.Biol., 19, 2012
2G6Q
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BU of 2g6q by Molmil
Crystal structure of ING2 PHD finger in complex with H3K4Me3 peptide
Descriptor: H3K4Me3 peptide, Inhibitor of growth protein 2, ZINC ION
Authors:Pena, P.V, Zhao, R, Kutateladze, T.G.
Deposit date:2006-02-24
Release date:2006-07-11
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular mechanism of histone H3K4me3 recognition by plant homeodomain of ING2.
Nature, 442, 2006
1R48
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BU of 1r48 by Molmil
Solution structure of the C-terminal cytoplasmic domain residues 468-497 of Escherichia coli protein ProP
Descriptor: Proline/betaine transporter
Authors:Zoetewey, D.L, Tripet, B.P, Kutateladze, T.G, Overduin, M.J, Wood, J.M, Hodges, R.S.
Deposit date:2003-10-03
Release date:2003-12-23
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution Structure of the C-terminal Antiparallel Coiled-coil Domain from Escherichia coli Osmosensor ProP.
J.Mol.Biol., 334, 2003
2GP5
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BU of 2gp5 by Molmil
Crystal structure of catalytic core domain of jmjd2A complexed with alpha-Ketoglutarate
Descriptor: 2-OXOGLUTARIC ACID, FE (II) ION, Jumonji domain-containing protein 2A, ...
Authors:Chen, Z, Zang, J, Whetstine, J, Hong, X, Davrazou, F, Kutateladze, T.G, Simpson, M, Dai, S, Hagman, J, Shi, Y, Zhang, G.
Deposit date:2006-04-16
Release date:2006-05-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Structural insights into histone demethylation by JMJD2 family members
Cell(Cambridge,Mass.), 125, 2006
6U04
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BU of 6u04 by Molmil
Crystal structure of human BRPF1 PZP bound to histone H3 tail
Descriptor: Histone H3.3,BRPF1, Peregrin, PRASEODYMIUM ION, ...
Authors:Klein, B.J, Kutateladze, T.G.
Deposit date:2019-08-13
Release date:2019-11-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Molecular Basis for the PZP Domain of BRPF1 Association with Chromatin.
Structure, 28, 2020
8GDX
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BU of 8gdx by Molmil
Crystal structure of JADE1 PZP domain
Descriptor: GLYCEROL, Protein Jade-1, ZINC ION
Authors:Klein, B.J, Liu, J, Kutateladze, T.G.
Deposit date:2023-03-06
Release date:2024-03-13
Last modified:2024-07-31
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:Guiding the HBO1 complex function through the JADE subunit.
Nat.Struct.Mol.Biol., 31, 2024
8GE0
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BU of 8ge0 by Molmil
Crystal structure of JADE1 PZP domain in complex with Histone H3
Descriptor: Histone H3.1,Protein Jade-1, ZINC ION
Authors:Klein, B.J, Liu, J, Kutateladze, T.G.
Deposit date:2023-03-06
Release date:2024-03-13
Last modified:2024-07-31
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Guiding the HBO1 complex function through the JADE subunit.
Nat.Struct.Mol.Biol., 31, 2024
5D7E
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BU of 5d7e by Molmil
Crystal structure of Taf14 YEATS domain in complex with H3K9ac
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, H3K9ac, ...
Authors:Andrews, F.H, Shanle, E.K, Strahl, B.D, Kutateladze, T.G.
Deposit date:2015-08-13
Release date:2015-09-23
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Association of Taf14 with acetylated histone H3 directs gene transcription and the DNA damage response.
Genes Dev., 29, 2015
7W9V
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BU of 7w9v by Molmil
Cryo-EM structure of nucleosome in complex with p300 acetyltransferase catalytic core (complex I)
Descriptor: DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
Authors:Hatazawa, S, Liu, J, Takizawa, Y, Zandian, M, Negishi, L, Kutateladze, T.G, Kurumizaka, H.
Deposit date:2021-12-10
Release date:2022-07-13
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.95 Å)
Cite:Structural basis for binding diversity of acetyltransferase p300 to the nucleosome.
Iscience, 25, 2022
5ERC
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BU of 5erc by Molmil
X-ray crystal structure of BRPF1 PZP domain
Descriptor: CALCIUM ION, Peregrin, ZINC ION
Authors:Klein, B.J, Andrews, F.H, Kutateladze, T.G.
Deposit date:2015-11-13
Release date:2015-12-30
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Bivalent interaction of the PZP domain of BRPF1 with the nucleosome impacts chromatin dynamics and acetylation.
Nucleic Acids Res., 44, 2016
6MIN
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BU of 6min by Molmil
Crystal structure of Taf14 YEATS domain G82A mutant in complex with histone H3K9cr
Descriptor: Histone H3K9cr, Transcription initiation factor TFIID subunit 14
Authors:Klein, B.J, Andrews, F.H, Kutateladze, T.G.
Deposit date:2018-09-19
Release date:2018-11-14
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural insights into the pi-pi-pi stacking mechanism and DNA-binding activity of the YEATS domain.
Nat Commun, 9, 2018
6MIM
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BU of 6mim by Molmil
Crystal structure of AF9 YEATS domain Y78W mutant in complex with histone H3K9cr
Descriptor: Histone H3K9cr, Protein AF-9
Authors:Vann, K.R, Klein, B.J, Kutateladze, T.G.
Deposit date:2018-09-19
Release date:2018-11-14
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.525 Å)
Cite:Structural insights into the pi-pi-pi stacking mechanism and DNA-binding activity of the YEATS domain.
Nat Commun, 9, 2018
6MIQ
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BU of 6miq by Molmil
Crystal structure of Taf14 YEATS domain in complex with histone H3K9bu
Descriptor: Histone H3K9bu, Transcription initiation factor TFIID subunit 14
Authors:Klein, B.J, Andrews, F.H, Vann, K.R, Kutateladze, T.G.
Deposit date:2018-09-19
Release date:2018-11-14
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural insights into the pi-pi-pi stacking mechanism and DNA-binding activity of the YEATS domain.
Nat Commun, 9, 2018
6MIO
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BU of 6mio by Molmil
Crystal structure of Taf14 YEATS domain in complex with histone H3K9pr
Descriptor: Histone H3K9pr, Transcription initiation factor TFIID subunit 14
Authors:Klein, B.J, Andrews, F.H, Vann, K.R, Kutateladze, T.G.
Deposit date:2018-09-19
Release date:2018-11-14
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural insights into the pi-pi-pi stacking mechanism and DNA-binding activity of the YEATS domain.
Nat Commun, 9, 2018
6MIL
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BU of 6mil by Molmil
Crystal structure of AF9 YEATS domain in complex with histone H3K9bu
Descriptor: DI(HYDROXYETHYL)ETHER, Histone H3K9bu, MALONATE ION, ...
Authors:Vann, K.R, Klein, B.J, Kutateladze, T.G.
Deposit date:2018-09-19
Release date:2018-11-14
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Structural insights into the pi-pi-pi stacking mechanism and DNA-binding activity of the YEATS domain.
Nat Commun, 9, 2018
6MIP
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BU of 6mip by Molmil
Crystal structure of Taf14 YEATS domain G82A mutant
Descriptor: DI(HYDROXYETHYL)ETHER, Transcription initiation factor TFIID subunit 14
Authors:Klein, B.J, Andrews, F.H, Kutateladze, T.G.
Deposit date:2018-09-19
Release date:2018-11-14
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural insights into the pi-pi-pi stacking mechanism and DNA-binding activity of the YEATS domain.
Nat Commun, 9, 2018

 

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