4J2G
| Atg13 HORMA domain | Descriptor: | KLTH0A00704p, SULFATE ION | Authors: | Jao, C, Stanley, R.E, Ragusa, M.J, Hurley, J.H. | Deposit date: | 2013-02-04 | Release date: | 2013-03-20 | Last modified: | 2013-04-17 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | A HORMA domain in Atg13 mediates PI 3-kinase recruitment in autophagy. Proc.Natl.Acad.Sci.USA, 110, 2013
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7SI1
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7SHV
| Crystal structure of BRAF kinase domain bound to GDC0879 | Descriptor: | 2-{4-[(1E)-1-(hydroxyimino)-2,3-dihydro-1H-inden-5-yl]-3-(pyridin-4-yl)-1H-pyrazol-1-yl}ethanol, CHLORIDE ION, Serine/threonine-protein kinase B-raf | Authors: | Kung, J.E, Sudhamsu, J. | Deposit date: | 2021-10-11 | Release date: | 2022-10-26 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.88 Å) | Cite: | Clearing the Path to Rapid High-Quality Protein Purification To Be Published
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5KZV
| Crystal structure of the xenopus Smoothened cysteine-rich domain (CRD) in complex with 20(S)-hydroxycholesterol | Descriptor: | (3alpha,8alpha)-cholest-5-ene-3,20-diol, Smoothened | Authors: | Huang, P, Kim, Y, Salic, A. | Deposit date: | 2016-07-25 | Release date: | 2016-08-17 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.616 Å) | Cite: | Cellular Cholesterol Directly Activates Smoothened in Hedgehog Signaling. Cell, 166, 2016
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5KZY
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5KZZ
| Crystal structure of the xenopus Smoothened cysteine-rich domain (CRD) in its apo-form | Descriptor: | ACETATE ION, GLYCEROL, Smoothened, ... | Authors: | Huang, P, Kim, Y, Salic, A. | Deposit date: | 2016-07-25 | Release date: | 2016-08-17 | Last modified: | 2024-11-06 | Method: | X-RAY DIFFRACTION (1.332 Å) | Cite: | Cellular Cholesterol Directly Activates Smoothened in Hedgehog Signaling. Cell, 166, 2016
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4OX0
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