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7SI1

Crystal structure of apo EGFR kinase domain

Summary for 7SI1
Entry DOI10.2210/pdb7si1/pdb
DescriptorEpidermal growth factor receptor, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, SULFATE ION, ... (4 entities in total)
Functional Keywordskinase, receptor tyrosine kinase, transferase
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total formula weight38036.80
Authors
Kung, J.E.,Wu, P.,Kiefer, J.R.,Sudhamsu, J. (deposition date: 2021-10-12, release date: 2022-10-26, Last modification date: 2023-10-18)
Primary citationChen, X.,Wendorff, T.,Jao, C.,Kung, J.E.,Liau, N.P.D.,Wu, P.,Yu, C.,Oh, A.,Boenig, G.,Wallweber, H.,Everett, C.,Miu, A.,Brillantes, B.,Mortara, K.,Murray, J.,Koth, C.M.,Sudhamsu, J.
Clearing the Path to Rapid High-Quality Protein Purification
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.6 Å)
Structure validation

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