7SI1
Crystal structure of apo EGFR kinase domain
Summary for 7SI1
Entry DOI | 10.2210/pdb7si1/pdb |
Descriptor | Epidermal growth factor receptor, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, SULFATE ION, ... (4 entities in total) |
Functional Keywords | kinase, receptor tyrosine kinase, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 38036.80 |
Authors | Kung, J.E.,Wu, P.,Kiefer, J.R.,Sudhamsu, J. (deposition date: 2021-10-12, release date: 2022-10-26, Last modification date: 2023-10-18) |
Primary citation | Chen, X.,Wendorff, T.,Jao, C.,Kung, J.E.,Liau, N.P.D.,Wu, P.,Yu, C.,Oh, A.,Boenig, G.,Wallweber, H.,Everett, C.,Miu, A.,Brillantes, B.,Mortara, K.,Murray, J.,Koth, C.M.,Sudhamsu, J. Clearing the Path to Rapid High-Quality Protein Purification To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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