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7SI1

Crystal structure of apo EGFR kinase domain

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AEpidermal growth factor receptorpolymer33137649.41UniProt (P00533)
Pfam (PF07714)
In PDB
Homo sapiens (Human)Proto-oncogene c-ErbB-1,Receptor tyrosine-protein kinase erbB-1
2A2-(N-MORPHOLINO)-ETHANESULFONIC ACIDnon-polymer195.21Chemie (MES)
3ASULFATE IONnon-polymer96.12Chemie (SO4)
4waterwater18.0267Chemie (HOH)
Sequence modifications
A: 695 - 1022 (UniProt: P00533)
PDBExternal DatabaseDetails
Gly 694-expression tag
Asn 1023-expression tag
Ser 1024-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight37649.4
Non-Polymers*Number of molecules3
Total formula weight387.4
All*Total formula weight38036.8
*Water molecules are not included.

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PDB entries from 2024-06-12

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