5W3S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5w3s by Molmil](/molmil-images/mine/5w3s) | Cryo-electron microscopy structure of a TRPML3 ion channel | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, CHOLESTEROL HEMISUCCINATE, Mucolipin-3 isoform 1, ... | Authors: | Hirschi, M, Herzik, M.A, Wie, J, Suo, Y, Borschel, W.F, Ren, D, Lander, G.C, Lee, S.Y. | Deposit date: | 2017-06-08 | Release date: | 2017-10-11 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (2.94 Å) | Cite: | Cryo-electron microscopy structure of the lysosomal calcium-permeable channel TRPML3. Nature, 550, 2017
|
|
4U9G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4u9g by Molmil](/molmil-images/mine/4u9g) | Crystal structure of an H-NOX protein from S. oneidensis in the Fe(II)CO ligation state, Q154A/Q155A/K156A mutant | Descriptor: | CARBON MONOXIDE, NO-binding heme-dependent sensor protein, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Herzik Jr, M.A, Jonnalagadda, R, Kuriyan, J, Marletta, M.A. | Deposit date: | 2014-08-06 | Release date: | 2014-10-01 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural insights into the role of iron-histidine bond cleavage in nitric oxide-induced activation of H-NOX gas sensor proteins. Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
4U9K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4u9k by Molmil](/molmil-images/mine/4u9k) | Crystal structure of an H-NOX protein from S. oneidensis in the Mn(II)NO ligation state, Q154A/Q155A/K156A mutant | Descriptor: | MANGANESE PROTOPORPHYRIN IX, NITRIC OXIDE, NO-binding heme-dependent sensor protein, ... | Authors: | Herzik Jr, M.A, Jonnalagadda, R, Kuriyan, J, Marletta, M.A. | Deposit date: | 2014-08-06 | Release date: | 2014-10-01 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structural insights into the role of iron-histidine bond cleavage in nitric oxide-induced activation of H-NOX gas sensor proteins. Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
4U99
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4u99 by Molmil](/molmil-images/mine/4u99) | Crystal structure of an H-NOX protein from S. oneidensis in the Fe(II) ligation state, Q154A/Q155A/K156A mutant | Descriptor: | NO-binding heme-dependent sensor protein, PROTOPORPHYRIN IX CONTAINING FE, SODIUM ION, ... | Authors: | Herzik Jr, M.A, Jonnalagadda, R, Kuriyan, J, Marletta, M.A. | Deposit date: | 2014-08-05 | Release date: | 2014-10-01 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural insights into the role of iron-histidine bond cleavage in nitric oxide-induced activation of H-NOX gas sensor proteins. Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
4U9J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4u9j by Molmil](/molmil-images/mine/4u9j) | Crystal structure of an H-NOX protein from S. oneidensis in the Mn(II) ligation state, Q154A/Q155A/K156A mutant | Descriptor: | MANGANESE PROTOPORPHYRIN IX, NO-binding heme-dependent sensor protein, SODIUM ION, ... | Authors: | Herzik Jr, M.A, Jonnalagadda, R, Kuriyan, J, Marletta, M.A. | Deposit date: | 2014-08-06 | Release date: | 2014-10-01 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural insights into the role of iron-histidine bond cleavage in nitric oxide-induced activation of H-NOX gas sensor proteins. Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
4U9B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4u9b by Molmil](/molmil-images/mine/4u9b) | Crystal structure of an H-NOX protein from S. oneidensis in the Fe(II)NO ligation state | Descriptor: | GLYCEROL, NITRIC OXIDE, NO-binding heme-dependent sensor protein, ... | Authors: | Herzik Jr, M.A, Jonnalagadda, R, Kuriyan, J, Marletta, M.A. | Deposit date: | 2014-08-05 | Release date: | 2014-10-01 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural insights into the role of iron-histidine bond cleavage in nitric oxide-induced activation of H-NOX gas sensor proteins. Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
5VY3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5vy3 by Molmil](/molmil-images/mine/5vy3) | |
5VY5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5vy5 by Molmil](/molmil-images/mine/5vy5) | Rabbit muscle aldolase using 200keV | Descriptor: | Fructose-bisphosphate aldolase A | Authors: | Herzik Jr, M.A, Wu, M, Lander, G.C. | Deposit date: | 2017-05-24 | Release date: | 2017-06-14 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Achieving better-than-3- angstrom resolution by single-particle cryo-EM at 200 keV. Nat. Methods, 14, 2017
|
|
5VY4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5vy4 by Molmil](/molmil-images/mine/5vy4) | |
6DT0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6dt0 by Molmil](/molmil-images/mine/6dt0) | Cryo-EM structure of a mitochondrial calcium uniporter | Descriptor: | CALCIUM ION, Mitochondrial calcium uniporter | Authors: | Yoo, J, Wu, M, Yin, Y, Herzik, M.A.J, Lander, G.C, Lee, S.-Y. | Deposit date: | 2018-06-14 | Release date: | 2018-07-11 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Cryo-EM structure of a mitochondrial calcium uniporter. Science, 361, 2018
|
|
7UT9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ut9 by Molmil](/molmil-images/mine/7ut9) | CryoEM structure of Azotobacter vinelandii nitrogenase complex (1:1 FeP:MoFeP, ADP/ATP-bound) during catalytic N2 reduction | Descriptor: | 3-HYDROXY-3-CARBOXY-ADIPIC ACID, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Rutledge, H.L, Cook, B, Tezcan, F.A, Herzik, M.A. | Deposit date: | 2022-04-26 | Release date: | 2022-08-17 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (2.44 Å) | Cite: | Structures of the nitrogenase complex prepared under catalytic turnover conditions. Science, 377, 2022
|
|
7UT6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ut6 by Molmil](/molmil-images/mine/7ut6) | C1 symmetric cryoEM structure of Azotobacter vinelandii MoFeP under non-turnover conditions | Descriptor: | 3-HYDROXY-3-CARBOXY-ADIPIC ACID, FE (III) ION, FE(8)-S(7) CLUSTER, ... | Authors: | Rutledge, H.L, Cook, B, Tezcan, F.A, Herzik, M.A. | Deposit date: | 2022-04-26 | Release date: | 2022-08-17 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (1.91 Å) | Cite: | Structures of the nitrogenase complex prepared under catalytic turnover conditions. Science, 377, 2022
|
|
7UT8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ut8 by Molmil](/molmil-images/mine/7ut8) | CryoEM structure of Azotobacter vinelandii nitrogenase complex (1:1 FeP:MoFeP, ATP-bound) during catalytic N2 reduction | Descriptor: | 3-HYDROXY-3-CARBOXY-ADIPIC ACID, ADENOSINE-5'-TRIPHOSPHATE, FE (III) ION, ... | Authors: | Rutledge, H.L, Cook, B, Tezcan, F.A, Herzik, M.A. | Deposit date: | 2022-04-26 | Release date: | 2022-08-17 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (2.43 Å) | Cite: | Structures of the nitrogenase complex prepared under catalytic turnover conditions. Science, 377, 2022
|
|
7UTA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7uta by Molmil](/molmil-images/mine/7uta) | CryoEM structure of Azotobacter vinelandii nitrogenase complex (2:1 FeP:MoFeP) inhibited by BeFx during catalytic N2 reduction | Descriptor: | 3-HYDROXY-3-CARBOXY-ADIPIC ACID, ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM, ... | Authors: | Rutledge, H.L, Cook, B.D, Nguyen, H.P.M, Tezcan, F.A, Herzik, M.A. | Deposit date: | 2022-04-26 | Release date: | 2022-08-17 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | Structures of the nitrogenase complex prepared under catalytic turnover conditions. Science, 377, 2022
|
|
7UT7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ut7 by Molmil](/molmil-images/mine/7ut7) | C2 symmetric cryoEM structure of Azotobacter vinelandii MoFeP under non-turnover conditions | Descriptor: | 3-HYDROXY-3-CARBOXY-ADIPIC ACID, FE (III) ION, FE(8)-S(7) CLUSTER, ... | Authors: | Rutledge, H.L, Cook, B.D, Tezcan, F.A, Herzik, M.A. | Deposit date: | 2022-04-26 | Release date: | 2022-08-17 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (1.91 Å) | Cite: | Structures of the nitrogenase complex prepared under catalytic turnover conditions. Science, 377, 2022
|
|
3MVC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3mvc by Molmil](/molmil-images/mine/3mvc) | High resolution crystal structure of the heme domain of GLB-6 from C. elegans | Descriptor: | Globin protein 6, NITRATE ION, PRASEODYMIUM ION, ... | Authors: | Yoon, J, Herzik Jr, M.A, Winter, M.B, Tran, R, Olea Jr, C, Marletta, M.A. | Deposit date: | 2010-05-03 | Release date: | 2010-06-16 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.401 Å) | Cite: | Structure and properties of a bis-histidyl ligated globin from Caenorhabditis elegans. Biochemistry, 49, 2010
|
|
3LAI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3lai by Molmil](/molmil-images/mine/3lai) | Structural insights into the molecular mechanism of H-NOX activation | Descriptor: | IMIDAZOLE, Methyl-accepting chemotaxis protein, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Olea Jr, C, Herzik Jr, M.A, Kuriyan, J, Marletta, M.A. | Deposit date: | 2010-01-06 | Release date: | 2010-03-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.144 Å) | Cite: | Structural insights into the molecular mechanism of H-NOX activation. Protein Sci., 19, 2010
|
|
3LAH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3lah by Molmil](/molmil-images/mine/3lah) | Structural insights into the molecular mechanism of H-NOX activation | Descriptor: | IMIDAZOLE, Methyl-accepting chemotaxis protein, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Olea Jr, C, Herzik Jr, M.A, Kuriyan, J, Marletta, M.A. | Deposit date: | 2010-01-06 | Release date: | 2010-03-16 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural insights into the molecular mechanism of H-NOX activation. Protein Sci., 19, 2010
|
|
6V20
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6v20 by Molmil](/molmil-images/mine/6v20) | |
6V21
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6v21 by Molmil](/molmil-images/mine/6v21) | |
3JCK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3jck by Molmil](/molmil-images/mine/3jck) | Structure of the yeast 26S proteasome lid sub-complex | Descriptor: | 26S proteasome complex subunit SEM1, 26S proteasome regulatory subunit RPN12, 26S proteasome regulatory subunit RPN3, ... | Authors: | Herzik Jr, M.A, Dambacher, C.M, Worden, E.J, Martin, A, Lander, G.C. | Deposit date: | 2015-12-20 | Release date: | 2016-01-20 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Atomic structure of the 26S proteasome lid reveals the mechanism of deubiquitinase inhibition. Elife, 5, 2016
|
|
8DPN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8dpn by Molmil](/molmil-images/mine/8dpn) | CryoEM structure of Azotobacter vinelandii nitrogenase MoFeP during catalytic N2 reduction | Descriptor: | 3-HYDROXY-3-CARBOXY-ADIPIC ACID, FE (III) ION, FE(8)-S(7) CLUSTER, ... | Authors: | Rutledge, H.L, Cook, B, Tezcan, F.A, Herzik, M.A. | Deposit date: | 2022-07-15 | Release date: | 2022-08-17 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (2.49 Å) | Cite: | Structures of the nitrogenase complex prepared under catalytic turnover conditions. Science, 377, 2022
|
|
6MHS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6mhs by Molmil](/molmil-images/mine/6mhs) | Structure of the human TRPV3 channel in a putative sensitized conformation | Descriptor: | Transient receptor potential cation channel subfamily V member 3 | Authors: | Zubcevic, L, Herzik, M.A, Wu, M, Borschel, W.F, Hirschi, M, Song, A, Lander, G.C, Lee, S.Y. | Deposit date: | 2018-09-18 | Release date: | 2018-10-03 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Conformational ensemble of the human TRPV3 ion channel. Nat Commun, 9, 2018
|
|
6MHX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6mhx by Molmil](/molmil-images/mine/6mhx) | Structure of human TRPV3 in the presence of 2-APB in C2 symmetry (2) | Descriptor: | Transient receptor potential cation channel subfamily V member 3 | Authors: | Zubcevic, L, Herzik, M.A, Wu, M, Borschel, W.F, Hirschi, M, Song, A, Lander, G.C, Lee, S.Y. | Deposit date: | 2018-09-18 | Release date: | 2018-10-03 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Conformational ensemble of the human TRPV3 ion channel. Nat Commun, 9, 2018
|
|
6MHW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6mhw by Molmil](/molmil-images/mine/6mhw) | Structure of human TRPV3 in the presence of 2-APB in C2 symmetry (1) | Descriptor: | Transient receptor potential cation channel subfamily V member 3 | Authors: | Zubcevic, L, Herzik, M.A, Wu, M, Borschel, W.F, Hirschi, M, Song, A, Lander, G.C, Lee, S.Y. | Deposit date: | 2018-09-18 | Release date: | 2018-10-03 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Conformational ensemble of the human TRPV3 ion channel. Nat Commun, 9, 2018
|
|