5W3S
Cryo-electron microscopy structure of a TRPML3 ion channel
Summary for 5W3S
Entry DOI | 10.2210/pdb5w3s/pdb |
Related | 5W3S |
EMDB information | 8764 |
Descriptor | Mucolipin-3 isoform 1, CHOLESTEROL HEMISUCCINATE, SODIUM ION, ... (5 entities in total) |
Functional Keywords | transient receptor potential channel, mucolipin, ion channel, membrane transport, trpml, trp channel, calcium channel, pip2, pi(3, 5)p2, lipid-gated channel, mucolipidosis, lysosomal ion channel, lysosome, transport protein |
Biological source | Callithrix jacchus (White-tufted-ear marmoset) |
Total number of polymer chains | 4 |
Total formula weight | 269340.12 |
Authors | Hirschi, M.,Herzik, M.A.,Wie, J.,Suo, Y.,Borschel, W.F.,Ren, D.,Lander, G.C.,Lee, S.Y. (deposition date: 2017-06-08, release date: 2017-10-11, Last modification date: 2024-03-13) |
Primary citation | Hirschi, M.,Herzik, M.A.,Wie, J.,Suo, Y.,Borschel, W.F.,Ren, D.,Lander, G.C.,Lee, S.Y. Cryo-electron microscopy structure of the lysosomal calcium-permeable channel TRPML3. Nature, 550:411-414, 2017 Cited by PubMed: 29019979DOI: 10.1038/nature24055 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.94 Å) |
Structure validation
Download full validation report