5W3S
Cryo-electron microscopy structure of a TRPML3 ion channel
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Mucolipin-3 isoform 1 | polymer | 561 | 65092.3 | 4 | UniProt (F6RG56) Pfam (PF21381) Pfam (PF08016) | Callithrix jacchus (White-tufted-ear marmoset) | |
| 2 | E, I, J, K, L... (A, B, C, D) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 12 | Chemie (Y01) | |||
| 3 | F, G, Q, R, S... (A, C, D) | SODIUM ION | non-polymer | 23.0 | 6 | Chemie (NA) | |||
| 4 | H, M, O, X (A, B, C, D) | 1,2-Distearoyl-sn-glycerophosphoethanolamine | non-polymer | 748.1 | 4 | Chemie (3PE) | |||
| 5 | AA, BA, CA, DA (A, B, C, D) | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 553 (UniProt: F6RG56)
| PDB | External Database | Details |
|---|---|---|
| Gln 138 | Asn 138 | engineered mutation |
| Ser 554 | - | expression tag |
| Asn 555 | - | expression tag |
| Leu 556 | - | expression tag |
| Glu 557 | - | expression tag |
| Val 558 | - | expression tag |
| Leu 559 | - | expression tag |
| Phe 560 | - | expression tag |
| Gln 561 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 260369.2 | |
| Non-Polymers* | Number of molecules | 22 |
| Total formula weight | 8970.9 | |
| All* | Total formula weight | 269340.1 |
