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1Q5X
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BU of 1q5x by Molmil
Structure of OF RRAA (MENG), a protein inhibitor of RNA processing
Descriptor: REGULATOR OF RNASE E ACTIVITY A
Authors:Monzingo, A.F, Gao, J, Qiu, J, Georgiou, G, Robertus, J.D.
Deposit date:2003-08-11
Release date:2003-09-30
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:The X-ray Structure of Escherichia coli RraA (MenG), A Protein Inhibitor of RNA Processing.
J.Mol.Biol., 332, 2003
1T3B
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BU of 1t3b by Molmil
X-ray Structure of DsbC from Haemophilus influenzae
Descriptor: Thiol:disulfide interchange protein dsbC
Authors:Zhang, M, Monzingo, A.F, Segatori, L, Georgiou, G, Robertus, J.D.
Deposit date:2004-04-26
Release date:2004-09-07
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of DsbC from Haemophilus influenzae.
Acta Crystallogr.,Sect.D, 60, 2004
3ETB
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BU of 3etb by Molmil
Crystal structure of the engineered neutralizing antibody M18 complexed with anthrax protective antigen domain 4
Descriptor: Anthrax Protective Antigen, Antibody M18 light chain and antibody M18 heavy chain linked with a synthetic (GGGGS)4 linker
Authors:Monzingo, A.F, Leysath, C.E, Barnett, J, Iverson, B.L, Georgiou, G, Robertus, J.D.
Deposit date:2008-10-07
Release date:2009-04-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Crystal structure of the engineered neutralizing antibody M18 complexed to domain 4 of the anthrax protective antigen.
J.Mol.Biol., 387, 2009
3ESU
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BU of 3esu by Molmil
Crystal structure of anthrax-neutralizing single-chain antibody 14b7
Descriptor: Antibody 14b7* light chain and antibody 14b7* heavy chain linked with a synthetic (GGGGS)4 linker
Authors:Monzingo, A.F, Maynard, J.A, Iverson, B.L, Georgiou, G, Robertus, J.D.
Deposit date:2008-10-06
Release date:2009-04-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal structure of the engineered neutralizing antibody m18 complexed to domain 4 of the anthrax protective antigen.
J.Mol.Biol., 387, 2009
3ET9
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BU of 3et9 by Molmil
Crystal structure of the engineered neutralizing antibody 1H
Descriptor: Antibody 1H light chain and antibody 1H heavy chain linked with a synthetic (GGGGS)4 linker
Authors:Leysath, C.E, Monzingo, A.F, Barnett, J, Iverson, B.L, Georgiou, G, Robertus, J.D.
Deposit date:2008-10-07
Release date:2009-04-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the engineered neutralizing antibody m18 complexed to domain 4 of the anthrax protective antigen.
J.Mol.Biol., 387, 2009
3ESV
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BU of 3esv by Molmil
Crystal structure of the engineered neutralizing antibody M18
Descriptor: Antibody M18 light chain and antibody M18 heavy chain linked with a synthetic (GGGGS)4 linker
Authors:Monzingo, A.F, Leysath, C.E, Barnett, J, Iverson, B.L, Georgiou, G, Robertus, J.D.
Deposit date:2008-10-06
Release date:2009-04-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the engineered neutralizing antibody m18 complexed to domain 4 of the anthrax protective antigen.
J.Mol.Biol., 387, 2009
3S7G
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BU of 3s7g by Molmil
Aglycosylated human igg1 fc fragment
Descriptor: Ig gamma-1 chain C region
Authors:Borrok, M.J, Georgiou, G.
Deposit date:2011-05-26
Release date:2012-05-30
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.13 Å)
Cite:Structural Analysis of an Aglycosylated Fc
To be Published
4OCS
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BU of 4ocs by Molmil
Crystal structure of human Fab CAP256-VRC26.10, a potent V1V2-directed HIV-1 neutralizing antibody
Descriptor: CAP256-VRC26.10 heavy chain, CAP256-VRC26.10 light chain
Authors:Gorman, J, Doria-Rose, N.A, Schramm, C.A, Moore, P.L, Mascola, J.R, Shapiro, L, Morris, L, Kwong, P.D.
Deposit date:2014-01-09
Release date:2014-02-26
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies.
Nature, 509, 2014
4OCW
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BU of 4ocw by Molmil
Crystal structure of human Fab CAP256-VRC26.06, a potent V1V2-directed HIV-1 neutralizing antibody
Descriptor: CAP256-VRC26.06 heavy chain, CAP256-VRC26.06 light chain
Authors:Gorman, J, Doria-Rose, N.A, Schramm, C.A, Moore, P.L, Mascola, J.R, Shapiro, L, Morris, L, Kwong, P.D.
Deposit date:2014-01-09
Release date:2014-02-26
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (3.001 Å)
Cite:Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies.
Nature, 509, 2014
7M8J
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BU of 7m8j by Molmil
SARS-CoV-2 S-NTD + Fab CM25
Descriptor: CM25 Fab - Heavy Chain, CM25 Fab - Light Chain, Spike protein S1
Authors:Johnson, N.V, Mclellan, J.S.
Deposit date:2021-03-29
Release date:2021-05-19
Last modified:2021-06-16
Method:ELECTRON MICROSCOPY (3.48 Å)
Cite:Prevalent, protective, and convergent IgG recognition of SARS-CoV-2 non-RBD spike epitopes.
Science, 372, 2021
4ET0
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BU of 4et0 by Molmil
Crystal structure of circularly permuted human asparaginase-like protein 1
Descriptor: L-asparaginase, SODIUM ION
Authors:Li, W.Z, Yogesha, S.D, Zhang, Y.
Deposit date:2012-04-23
Release date:2012-09-26
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Uncoupling Intramolecular Processing and Substrate Hydrolysis in the N-Terminal Nucleophile Hydrolase hASRGL1 by Circular Permutation.
Acs Chem.Biol., 7, 2012
5IBU
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BU of 5ibu by Molmil
6652 Fab (unbound)
Descriptor: 6652 Heavy Chain, 6652 Light Chain
Authors:Raymond, D.D, Harrison, S.C.
Deposit date:2016-02-22
Release date:2016-11-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Influenza immunization elicits antibodies specific for an egg-adapted vaccine strain.
Nat. Med., 22, 2016
5IBT
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BU of 5ibt by Molmil
UCA Fab (unbound) from 6515 Lineage
Descriptor: GLYCEROL, UCA Heavy Chain, UCA Light Chain
Authors:Raymond, D.D, Harrison, S.C.
Deposit date:2016-02-22
Release date:2016-11-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Influenza immunization elicits antibodies specific for an egg-adapted vaccine strain.
Nat. Med., 22, 2016
5IBL
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BU of 5ibl by Molmil
Human antibody 6639 in complex with influenza hemagglutinin H1 X-181
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 6639 Heavy Chain, 6639 Light Chain, ...
Authors:Raymond, D.D, Harrison, S.C.
Deposit date:2016-02-22
Release date:2016-11-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.39 Å)
Cite:Influenza immunization elicits antibodies specific for an egg-adapted vaccine strain.
Nat. Med., 22, 2016
6OVG
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BU of 6ovg by Molmil
L-Methionine Depletion with an Engineered Human Enzyme Disrupts Prostate Cancer Metabolism
Descriptor: Cystathionine gamma-lyase, SULFATE ION
Authors:Yan, W, Irani, S, Zhang, J.
Deposit date:2019-05-07
Release date:2020-04-22
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.719 Å)
Cite:Enzyme-mediated depletion of serum l-Met abrogates prostate cancer growth via multiple mechanisms without evidence of systemic toxicity.
Proc.Natl.Acad.Sci.USA, 117, 2020
6P79
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BU of 6p79 by Molmil
Engineered single chain antibody C9+C14 ScFv
Descriptor: Engineered antibody heavy chain, Engineered antibody light chain
Authors:Zhang, Y, Li, W, Marshall, N.
Deposit date:2019-06-05
Release date:2020-04-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.583 Å)
Cite:Computer-based Engineering of Thermostabilized Antibody Fragments.
Aiche J, 66, 2020
7S3V
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BU of 7s3v by Molmil
Structure of HsKYNase_66, an evolved variant of human kynureninase with greatly increased activity towards kynurenine
Descriptor: Kynureninase
Authors:Burkholder, N.T, Zhang, Y.J.
Deposit date:2021-09-08
Release date:2022-12-21
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.249 Å)
Cite:Bypassing evolutionary dead ends and switching the rate-limiting step of a human immunotherapeutic enzyme.
Nat Catal, 5, 2022
7KJP
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BU of 7kjp by Molmil
Disulfide Stabilized Norovirus GI.1 VLP Shell Region
Descriptor: Capsid protein VP1
Authors:Gorman, J, Kwong, P.D.
Deposit date:2020-10-26
Release date:2020-12-02
Last modified:2020-12-30
Method:ELECTRON MICROSCOPY (3.86 Å)
Cite:Disulfide stabilization of human norovirus GI.1 virus-like particles focuses immune response toward blockade epitopes.
NPJ Vaccines, 5, 2020
8TMA
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BU of 8tma by Molmil
Antibody N3-1 bound to RBD in the up conformation
Descriptor: N3-1 Fab heavy chain, N3-1 Fab light chain, Spike glycoprotein
Authors:Hsieh, C.-L, McLellan, J.S.
Deposit date:2023-07-29
Release date:2024-01-17
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:SARS-COV-2 Omicron variants conformationally escape a rare quaternary antibody binding mode.
Commun Biol, 6, 2023
8TM1
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BU of 8tm1 by Molmil
Antibody N3-1 bound to RBDs in the up and down conformations
Descriptor: N3-1 Fab heavy chain, N3-1 Fab light chain, Spike glycoprotein
Authors:Hsieh, C.-L, McLellan, J.S.
Deposit date:2023-07-27
Release date:2024-01-17
Method:ELECTRON MICROSCOPY (2.79 Å)
Cite:SARS-COV-2 Omicron variants conformationally escape a rare quaternary antibody binding mode.
Commun Biol, 6, 2023
2E7P
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BU of 2e7p by Molmil
Crystal structure of the holo form of glutaredoxin C1 from populus tremula x tremuloides
Descriptor: FE2/S2 (INORGANIC) CLUSTER, GLUTATHIONE, Glutaredoxin
Authors:Unno, H, Takahashi, T, Kawakami, T, Aimoto, S, Hase, T, Kusunoki, M, Rouhier, N, Jacquot, J.P.
Deposit date:2007-01-12
Release date:2007-09-25
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Functional, structural, and spectroscopic characterization of a glutathione-ligated [2Fe-2S] cluster in poplar glutaredoxin C1
Proc.Natl.Acad.Sci.Usa, 104, 2007
6MTO
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BU of 6mto by Molmil
Crystal structure of VRC42.01 Fab in complex with T117-F MPER scaffold
Descriptor: Antibody VRC42.01 Fab heavy chain, Antibody VRC42.01 Fab light chain, VRC42 epitope T117-F scaffold
Authors:Kwon, Y.D, Druz, A, Law, W.H, Peng, D, Zhang, B, Doria-Rose, N.A, Kwong, P.D.
Deposit date:2018-10-21
Release date:2019-03-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.634 Å)
Cite:Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual.
Immunity, 50, 2019
6MTR
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BU of 6mtr by Molmil
Crystal structure of VRC43.01 Fab
Descriptor: Antibody VRC43.01 Fab heavy chain, Antibody VRC43.01 Fab light chain
Authors:Kwon, Y.D, Druz, A, Law, W.H, Peng, D, Zhang, B, Doria-Rose, N.A, Kwong, P.D.
Deposit date:2018-10-21
Release date:2019-03-27
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.798 Å)
Cite:Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual.
Immunity, 50, 2019
6MTS
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BU of 6mts by Molmil
Crystal structure of VRC43.03 Fab
Descriptor: Antibody VRC43.03 Fab heavy chain, Antibody VRC43.03 Fab light chain
Authors:Kwon, Y.D, Druz, A, Law, W.H, Peng, D, Doria-Rose, N.A, Kwong, P.D.
Deposit date:2018-10-21
Release date:2019-03-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.437 Å)
Cite:Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual.
Immunity, 50, 2019
6MTP
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BU of 6mtp by Molmil
Crystal structure of VRC42.04 Fab in complex with gp41 peptide
Descriptor: Antibody VRC42.04 Fab heavy chain, Antibody VRC42.04 Fab light chain, RV217 founder virus gp41 peptide
Authors:Kwon, Y.D, Druz, A, Law, W.H, Peng, D, Zhang, B, Doria-Rose, N.A, Kwong, P.D.
Deposit date:2018-10-21
Release date:2019-03-27
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.036 Å)
Cite:Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual.
Immunity, 50, 2019

 

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數據於2024-07-10公開中

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