1ZNV
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![BU of 1znv by Molmil](/molmil-images/mine/1znv) | How a His-metal finger endonuclease ColE7 binds and cleaves DNA with a transition metal ion cofactor | Descriptor: | Colicin E7, Colicin E7 immunity protein, NICKEL (II) ION, ... | Authors: | Doudeva, L.G, Huang, H, Hsia, K.C, Shi, Z, Li, C.L, Shen, Y, Yuan, H.S. | Deposit date: | 2005-05-12 | Release date: | 2006-03-14 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structural analysis and metal-dependent stability and activity studies of the ColE7 endonuclease domain in complex with DNA/Zn2+ or inhibitor/Ni2+ Protein Sci., 15, 2006
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1ZNS
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![BU of 1zns by Molmil](/molmil-images/mine/1zns) | Crystal structure of N-ColE7/12-bp DNA/Zn complex | Descriptor: | 5'-D(*CP*GP*GP*GP*AP*TP*AP*TP*CP*CP*CP*G)-3', Colicin E7, ZINC ION | Authors: | Doudeva, L.G, Huang, H, Hsia, K.C, Shi, Z, Li, C.L, Shen, Y, Yuan, H.S. | Deposit date: | 2005-05-12 | Release date: | 2006-03-14 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structural analysis and metal-dependent stability and activity studies of the ColE7 endonuclease domain in complex with DNA/Zn2+ or inhibitor/Ni2+ Protein Sci., 15, 2006
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4IUF
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![BU of 4iuf by Molmil](/molmil-images/mine/4iuf) | Crystal Structure of Human TDP-43 RRM1 Domain in Complex with a Single-stranded DNA | Descriptor: | 5'-D(*GP*TP*TP*GP*(XUA)P*GP*CP*GP*T)-3', TAR DNA-binding protein 43 | Authors: | Kuo, P.H, Doudeva, L.G, Wang, Y.T, Yang, W.Z, Yuan, H.S. | Deposit date: | 2013-01-21 | Release date: | 2014-01-29 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.752 Å) | Cite: | The crystal structure of TDP-43 RRM1-DNA complex reveals the specific recognition for UG- and TG-rich nucleic acids. Nucleic Acids Res., 42, 2014
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4Y0F
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![BU of 4y0f by Molmil](/molmil-images/mine/4y0f) | Crystal Structure of Human TDP-43 RRM1 Domain in Complex with an Unmodified Single-stranded DNA | Descriptor: | DNA (5'-D(*GP*TP*TP*GP*AP*GP*CP*GP*TP*T)-3'), TAR DNA-binding protein 43 | Authors: | Chiang, C.H, Kuo, P.H, Doudeva, L.G, Wang, Y.T, Yuan, H.S. | Deposit date: | 2015-02-06 | Release date: | 2016-02-10 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.648 Å) | Cite: | Structural analysis of disease-related TDP-43 D169G mutation: linking enhanced stability and caspase cleavage efficiency to protein accumulation Sci Rep, 6, 2016
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3KRN
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![BU of 3krn by Molmil](/molmil-images/mine/3krn) | Crystal Structure of C. elegans cell-death-related nuclease 5(CRN-5) | Descriptor: | Protein C14A4.5, confirmed by transcript evidence | Authors: | Yang, C.-C, Wang, Y.-T, Hsiao, Y.-Y, Doudeva, L.G, Chow, S.Y, Yuan, H.S. | Deposit date: | 2009-11-19 | Release date: | 2010-01-26 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.918 Å) | Cite: | Structural and biochemical characterization of CRN-5 and Rrp46: an exosome component participating in apoptotic DNA degradation Rna, 16, 2010
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1M08
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![BU of 1m08 by Molmil](/molmil-images/mine/1m08) | Crystal structure of the unbound nuclease domain of ColE7 | Descriptor: | Colicin E7, PHOSPHATE ION, ZINC ION | Authors: | Cheng, Y.S, Hsia, K.C, Doudeva, L.G, Chak, K.F, Yuan, H.S. | Deposit date: | 2002-06-12 | Release date: | 2002-12-11 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The Crystal Structure of the Nuclease Domain of Colicin E7 Suggests a Mechanism for Binding to Double-stranded DNA by the H-N-H Endonucleases J.mol.biol., 324, 2002
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1MZ8
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![BU of 1mz8 by Molmil](/molmil-images/mine/1mz8) | CRYSTAL STRUCTURES OF THE NUCLEASE DOMAIN OF COLE7/IM7 IN COMPLEX WITH A PHOSPHATE ION AND A ZINC ION | Descriptor: | Colicin E7, Colicin E7 immunity protein, PHOSPHATE ION, ... | Authors: | Sui, M.J, Tsai, L.C, Hsia, K.C, Doudeva, L.G, Ku, W.Y, Han, G.W, Yuan, H.S. | Deposit date: | 2002-10-07 | Release date: | 2002-12-23 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Metal ions and phosphate binding in the H-N-H motif: crystal structures of the nuclease domain of ColE7/Im7 in complex with a phosphate ion and different divalent metal ions PROTEIN SCI., 11, 2002
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2AXC
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![BU of 2axc by Molmil](/molmil-images/mine/2axc) | Crystal structure of ColE7 translocation domain | Descriptor: | Colicin E7, GLYCEROL, SULFATE ION | Authors: | Cheng, Y.S, Shi, Z, Doudeva, L.G, Yang, W.Z, Chak, K.F, Yuan, H.S. | Deposit date: | 2005-09-04 | Release date: | 2006-03-14 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | High-resolution crystal structure of a truncated ColE7 translocation domain: implications for colicin transport across membranes J.Mol.Biol., 356, 2006
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3HKM
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![BU of 3hkm by Molmil](/molmil-images/mine/3hkm) | Crystal Structure of rice(Oryza sativa) Rrp46 | Descriptor: | Os03g0854200 protein | Authors: | Yang, C.-C, Wang, Y.-T, Hsiao, Y.-Y, Doudeva, L.G, Yuan, H.S. | Deposit date: | 2009-05-25 | Release date: | 2010-01-26 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.9845 Å) | Cite: | Structural and biochemical characterization of CRN-5 and Rrp46: an exosome component participating in apoptotic DNA degradation Rna, 16, 2010
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3FBD
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![BU of 3fbd by Molmil](/molmil-images/mine/3fbd) | |
2IVH
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![BU of 2ivh by Molmil](/molmil-images/mine/2ivh) | Crystal structure of the nuclease domain of ColE7 (H545Q mutant) in complex with an 18-bp duplex DNA | Descriptor: | 5'-D(*GP*GP*AP*AP*TP*TP*CP*GP*AP*TP *CP*GP*AP*AP*TP*TP*CP*C)-3', COLCIN-E7, ZINC ION | Authors: | Wang, Y.T, Yang, W.J, Li, C.L, Doudeva, L.G, Yuan, H.S. | Deposit date: | 2006-06-13 | Release date: | 2007-01-02 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural Basis for Sequence-Dependent DNA Cleavage by Nonspecific Endonucleases. Nucleic Acids Res., 35, 2007
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2IVK
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![BU of 2ivk by Molmil](/molmil-images/mine/2ivk) | Crystal structure of the periplasmic endonuclease Vvn complexed with a 16-bp DNA | Descriptor: | 5'-D(*AP*AP*TP*TP*CP*GP*AP*TP*CP*GP *AP*AP*TP*TP*C)-3', 5'-D(*GP*AP*AP*TP*TP*CP*GP*AP*TP*CP *GP*AP*AP*TP*T)-3', 5'-D(*GP*AP*AP*TP*TP*CP*GP*AP*TP*CP *GP*AP*AP*TP*TP*C)-3', ... | Authors: | Wang, Y.T, Yang, W.J, Li, C.L, Doudeva, L.G, Yuan, H.S. | Deposit date: | 2006-06-14 | Release date: | 2007-01-02 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural Basis for Sequence-Dependent DNA Cleavage by Nonspecific Endonucleases. Nucleic Acids Res., 35, 2007
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3S5B
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![BU of 3s5b by Molmil](/molmil-images/mine/3s5b) | |
4Y00
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![BU of 4y00 by Molmil](/molmil-images/mine/4y00) | Crystal Structure of Human TDP-43 RRM1 Domain with D169G Mutation in Complex with an Unmodified Single-stranded DNA | Descriptor: | DNA (5'-D(P*TP*TP*GP*AP*GP*CP*GP*T)-3'), TAR DNA-binding protein 43 | Authors: | Chiang, C.H, Kuo, P.H, Yang, W.Z, Yuan, H.S. | Deposit date: | 2015-02-05 | Release date: | 2016-02-10 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural analysis of disease-related TDP-43 D169G mutation: linking enhanced stability and caspase cleavage efficiency to protein accumulation Sci Rep, 6, 2016
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3D2W
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![BU of 3d2w by Molmil](/molmil-images/mine/3d2w) | Crystal structure of mouse TDP-43 RRM2 domain in complex with DNA | Descriptor: | DNA (5'-D(*DGP*DTP*DTP*DGP*DAP*DGP*DCP*DGP*DTP*DT)-3'), PHOSPHATE ION, TAR DNA-binding protein 43 | Authors: | Kuo, P.H, Yuan, H.S. | Deposit date: | 2008-05-09 | Release date: | 2009-04-07 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural insights into TDP-43 in nucleic-acid binding and domain interactions Nucleic Acids Res., 37, 2009
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4QN0
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![BU of 4qn0 by Molmil](/molmil-images/mine/4qn0) | Crystal structure of the CPS-6 mutant Q130K | Descriptor: | Endonuclease G, mitochondrial, MAGNESIUM ION | Authors: | Lin, J.L.J, Yuan, H.S. | Deposit date: | 2014-06-17 | Release date: | 2015-06-17 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.74 Å) | Cite: | Oxidative Stress Impairs Cell Death by Repressing the Nuclease Activity of Mitochondrial Endonuclease G Cell Rep, 16, 2016
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