7EUE
 
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7F6X
 | | Structural and mechanistic studies of a novel non-heme iron epimerase/lyase and its utilization in chemoselective synthesis. | | Descriptor: | 1H-INDOLE-3-CARBALDEHYDE, Cupin domain-containing protein, FE (III) ION, ... | | Authors: | Li, T.L, Li, Y.S, Chen, M.H. | | Deposit date: | 2021-06-26 | | Release date: | 2022-03-16 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.16 Å) | | Cite: | Structural and Mechanistic Bases for StnK3 and Its Mutant-MediatedLewis-Acid-Dependent Epimerization and Retro-Aldol Reactions.
Acs Catalysis, 12, 2022
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7EUZ
 | | Structural and mechanistic studies of a novel non-heme iron epimerase/lyase and its utilization in chemoselective synthesis. | | Descriptor: | (2S,3R)-2-azanyl-3-(1H-indol-3-yl)butanoic acid, Cupin domain-containing protein, FE (III) ION, ... | | Authors: | Li, T.L, Li, Y.S, Chen, M.H. | | Deposit date: | 2021-05-19 | | Release date: | 2022-03-16 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.91028166 Å) | | Cite: | Structural and Mechanistic Bases for StnK3 and Its Mutant-Mediated Lewis-Acid-Dependent Epimerization and Retro-Aldol Reactions.
Acs Catalysis, 12, 2022
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7EUP
 | | Structural and mechanistic studies of a novel non-heme iron epimerase/lyase and its utilization in chemoselective synthesis. | | Descriptor: | (2S,3R)-2-azanyl-3-phenyl-butanoic acid, Cupin domain-containing protein, FE (III) ION | | Authors: | Li, T.L, Li, Y.S, Chen, M.H. | | Deposit date: | 2021-05-18 | | Release date: | 2022-03-16 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.11043429 Å) | | Cite: | Structural and Mechanistic Bases for StnK3 and Its Mutant-Mediated Lewis-Acid-Dependent Epimerization and Retro-Aldol Reactions.
Acs Catalysis, 12, 2022
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7EQK
 | | Structural and mechanistic studies of a novel non-heme iron epimerase/lyase and its utilization in chemoselective synthesis. | | Descriptor: | (E)-3-(1H-indol-3-yl)-2-oxidanyl-but-2-enoic acid, 1-(1~{H}-indol-3-yl)ethanone, Cupin domain-containing protein, ... | | Authors: | Li, T.L, Li, Y.S, Chen, M.H. | | Deposit date: | 2021-05-03 | | Release date: | 2022-03-16 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.04001021 Å) | | Cite: | Structural and Mechanistic Bases for StnK3 and Its Mutant-Mediated Lewis-Acid-Dependent Epimerization and Retro-Aldol Reactions.
Acs Catalysis, 12, 2022
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7EU6
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8DI5
 | | Cryo-EM structure of SARS-CoV-2 Beta (B.1.351) spike protein in complex with VH domain F6 (focused refinement of RBD and VH F6) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, VH F6 | | Authors: | Zhu, X, Saville, J.W, Mannar, D, Berezuk, A.M, Subramaniam, S. | | Deposit date: | 2022-06-28 | | Release date: | 2022-08-24 | | Method: | ELECTRON MICROSCOPY (3.04 Å) | | Cite: | Potent and broad neutralization of SARS-CoV-2 variants of concern (VOCs) including omicron sub-lineages BA.1 and BA.2 by biparatopic human VH domains.
Iscience, 25, 2022
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8SG1
 | | Cryo-EM structure of CMKLR1 signaling complex | | Descriptor: | CHOLESTEROL, Chemerin 9, Chemerin-like receptor 1, ... | | Authors: | Zhang, X, Zhang, C. | | Deposit date: | 2023-04-11 | | Release date: | 2023-11-01 | | Last modified: | 2023-12-20 | | Method: | ELECTRON MICROSCOPY (2.94 Å) | | Cite: | Structural basis of G protein-Coupled receptor CMKLR1 activation and signaling induced by a chemerin-derived agonist.
Plos Biol., 21, 2023
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6IIY
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6IIX
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7V4M
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7V4O
 | | Unique non-heme hydroxylase in biosynthesis of nucleoside antibiotic pathway uncover mechanism of reaction | | Descriptor: | 3,6,9,12,15-PENTAOXAHEPTADECANE, Beta-hydroxylase | | Authors: | Li, T.L, Saeid, M.Z. | | Deposit date: | 2021-08-13 | | Release date: | 2022-02-23 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | beta-Hydroxylation of alpha-amino-beta-hydroxylbutanoyl-glycyluridine catalyzed by a nonheme hydroxylase ensures the maturation of caprazamycin
Commun Chem, 5, 2022
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7V4N
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7V4P
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7V4F
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8THR
 | | Structure of the human vesicular monoamine transporter 2 (VMAT2) bound to tetrabenazine in an occluded conformation | | Descriptor: | (3S,5R,11bS)-9,10-dimethoxy-3-(2-methylpropyl)-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one, fluorescent protein mVenus,Synaptic vesicular amine transporter,GFP nano body,Synaptic vesicular amine transporter,Synaptic vesicular amine transporter | | Authors: | Dalton, M.P, Coleman, J.A. | | Deposit date: | 2023-07-17 | | Release date: | 2023-10-25 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (3.12 Å) | | Cite: | Structural mechanisms for VMAT2 inhibition by tetrabenazine.
Elife, 12, 2024
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7LQK
 | | Crystal structure of the R375A mutant of LeuT | | Descriptor: | ALANINE, Na(+):neurotransmitter symporter (Snf family), SODIUM ION, ... | | Authors: | Font, J, Aguilar, J, Galli, A, Ryan, R. | | Deposit date: | 2021-02-13 | | Release date: | 2021-05-19 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Psychomotor impairments and therapeutic implications revealed by a mutation associated with infantile Parkinsonism-Dystonia.
Elife, 10, 2021
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7LQL
 | | Crystal structure of the R375D mutant of LeuT | | Descriptor: | ALANINE, Na(+):neurotransmitter symporter (Snf family), SODIUM ION, ... | | Authors: | Font, J, Aguilar, J, Galli, A, Ryan, R. | | Deposit date: | 2021-02-13 | | Release date: | 2021-05-19 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Psychomotor impairments and therapeutic implications revealed by a mutation associated with infantile Parkinsonism-Dystonia.
Elife, 10, 2021
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7LQJ
 | | Crystal structure of LeuT bound to L-Alanine | | Descriptor: | ALANINE, Na(+):neurotransmitter symporter (Snf family), SODIUM ION, ... | | Authors: | Font, J, Aguilar, J, Galli, A, Ryan, R. | | Deposit date: | 2021-02-13 | | Release date: | 2021-05-19 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.144 Å) | | Cite: | Psychomotor impairments and therapeutic implications revealed by a mutation associated with infantile Parkinsonism-Dystonia.
Elife, 10, 2021
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