1JJS
| NMR Structure of IBiD, A Domain of CBP/p300 | Descriptor: | CREB-BINDING PROTEIN | Authors: | Lin, C.H, Hare, B.J, Wagner, G, Harrison, S.C, Maniatis, T, Fraenkel, E. | Deposit date: | 2001-07-09 | Release date: | 2001-10-03 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | A small domain of CBP/p300 binds diverse proteins: solution structure and functional studies. Mol.Cell, 8, 2001
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107D
| SOLUTION STRUCTURE OF THE COVALENT DUOCARMYCIN A-DNA DUPLEX COMPLEX | Descriptor: | 4-HYDROXY-2,8-DIMETHYL-1-OXO-6-(4,5,6-TRIMETHOXY-1H-INDOLE-2-CARBONYL)-1,2,3,6,7,8-HEXAHYDRO-3,6-DIAZA-AS-INDACENE-2-CARBOXYLIC ACID METHYL ESTER, DNA (5'-D(*CP*CP*TP*TP*TP*TP*C)-3'), DNA (5'-D(*GP*AP*AP*AP*AP*GP*G)-3') | Authors: | Lin, C.H, Patel, D.J. | Deposit date: | 1995-01-17 | Release date: | 1995-05-08 | Last modified: | 2024-03-13 | Method: | SOLUTION NMR | Cite: | Solution structure of the covalent duocarmycin A-DNA duplex complex. J.Mol.Biol., 248, 1995
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1AW4
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2ARG
| FORMATION OF AN AMINO ACID BINDING POCKET THROUGH ADAPTIVE ZIPPERING-UP OF A LARGE DNA HAIRPIN LOOP, NMR, 9 STRUCTURES | Descriptor: | ARGININEAMIDE, DNA APTAMER [5'-D (*TP*GP*AP*CP*CP*AP*GP*GP*GP*CP*AP*AP*AP*CP*GP*GP*TP*AP* GP*GP*TP*GP*AP*GP*TP*GP*GP*TP*CP*A)-3'] | Authors: | Lin, C.H, Wang, W, Jones, R.A, Patel, D.J. | Deposit date: | 1998-08-19 | Release date: | 1999-03-23 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Formation of an amino-acid-binding pocket through adaptive zippering-up of a large DNA hairpin loop. Chem.Biol., 5, 1998
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1OLD
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1HWV
| MOLECULAR TOPOLOGY OF POLYCYCLIC AROMATIC CARCINOGENS DETERMINES DNA ADDUCT CONFORMATION: A LINK TO TUMORIGENIC ACTIVITY | Descriptor: | (1S)-1,2,3,4-TETRAHYDRO-BENZO[C]PHENANTHRENE-2,3,4-TRIOL, 5'-D(*CP*CP*AP*TP*CP*GP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*CP*GP*AP*TP*GP*G)-3' | Authors: | Patel, D.J, Lin, C.H, Geacintov, N.E, Broyde, S, Huang, X, Kolbanovskii, A, Hingerty, B.E, Amin, S. | Deposit date: | 2001-01-10 | Release date: | 2001-03-21 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Molecular topology of polycyclic aromatic carcinogens determines DNA adduct conformation: a link to tumorigenic activity. J.Mol.Biol., 306, 2001
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1HX4
| MOLECULAR TOPOLOGY OF POLYCYCLIC AROMATIC CARCINOGENS DETERMINES DNA ADDUCT CONFORMATION: A LINK TO TUMORIGENIC ACTIVITY | Descriptor: | (1R)-1,2,3,4-TETRAHYDRO-BENZO[C]PHENANTHRENE-2,3,4-TRIOL, 5'-D(*CP*CP*AP*TP*CP*GP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*CP*GP*AP*TP*GP*G)-3' | Authors: | Patel, D.J, Lin, C.H, Geacintov, N.E, Broyde, S, Huang, X, Kolbanovskii, A, Hingerty, B.E, Amin, S. | Deposit date: | 2001-01-11 | Release date: | 2001-03-21 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Molecular topology of polycyclic aromatic carcinogens determines DNA adduct conformation: a link to tumorigenic activity. J.Mol.Biol., 306, 2001
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5H9P
| Crystal Structure of Human Galectin-3 CRD in Complex with TD139 | Descriptor: | 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-beta-D-galactopyranosyl 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-1-thio-beta-D-galactopyranoside, Galectin-3 | Authors: | Hsieh, T.J, Lin, H.Y, Lin, C.H. | Deposit date: | 2015-12-29 | Release date: | 2016-06-29 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Dual thio-digalactoside-binding modes of human galectins as the structural basis for the design of potent and selective inhibitors Sci Rep, 6, 2016
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4Y24
| Complex of human Galectin-1 and TD-139 | Descriptor: | 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-beta-D-galactopyranosyl 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-1-thio-beta-D-galactopyranoside, Galectin-1 | Authors: | Lin, H.Y, Hsieh, T.J, Lin, C.H. | Deposit date: | 2015-02-09 | Release date: | 2016-04-27 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | Dual thio-digalactoside-binding modes of human galectins as the structural basis for the design of potent and selective inhibitors. Sci Rep, 6, 2016
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4Y1X
| Complex of human Galectin-1 and Galbeta1-4(6OSO3)GlcNAc | Descriptor: | Galectin-1, beta-D-galactopyranose-(1-4)-methyl 2-acetamido-2-deoxy-6-O-sulfo-beta-D-glucopyranoside | Authors: | Lin, H.Y, Hsieh, T.J, Lin, C.H. | Deposit date: | 2015-02-09 | Release date: | 2016-04-06 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structural basis of human galectin-1 inhibition with Ki values in the micro- to nanomolar range To Be Published
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4XBN
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4XBQ
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4Y1V
| Complex of human Galectin-1 and Galbeta1-3GlcNAc | Descriptor: | Galectin-1, beta-D-galactopyranose-(1-3)-methyl 2-acetamido-2-deoxy-beta-D-glucopyranoside | Authors: | Lin, H.Y, Hsieh, T.J, Lin, C.H. | Deposit date: | 2015-02-09 | Release date: | 2016-04-06 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | Structural basis of human galectin-1 inhibition with Ki values in the micro- to nanomolar range To Be Published
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4Y1U
| Complex of human Galectin-1 and Galbeta1-4GlcNAc | Descriptor: | Galectin-1, beta-D-galactopyranose-(1-4)-methyl 2-acetamido-2-deoxy-beta-D-glucopyranoside | Authors: | Lin, H.Y, Hsieh, T.J, Lin, C.H. | Deposit date: | 2015-02-09 | Release date: | 2016-04-06 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.762 Å) | Cite: | Structural basis of human galectin-1 inhibition with Ki values in the micro- to nanomolar range To Be Published
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4Y26
| Complex of human Galectin-7 and Galbeta1-3(6OSO3)GlcNAc | Descriptor: | Galectin-7, beta-D-galactopyranose-(1-3)-methyl 2-acetamido-2-deoxy-6-O-sulfo-beta-D-glucopyranoside | Authors: | Lin, H.Y, Hsieh, T.J, Lin, C.H. | Deposit date: | 2015-02-09 | Release date: | 2016-04-06 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.611 Å) | Cite: | Structural basis of human galectin-1 inhibition with Ki values in the micro- to nanomolar range To Be Published
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4Y22
| Complex of human Galectin-1 and (3OSO3)Galbeta1-3GlcNAc | Descriptor: | 3-O-sulfo-beta-D-galactopyranose-(1-3)-methyl 2-acetamido-2-deoxy-beta-D-glucopyranoside, Galectin-1 | Authors: | Lin, H.Y, Hsieh, T.J, Lin, C.H. | Deposit date: | 2015-02-09 | Release date: | 2016-04-06 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis of human galectin-1 inhibition with Ki values in the micro- to nanomolar range To Be Published
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4Y1Z
| Complex of human Galectin-1 and Galbeta1-4(6CO2)GlcNAc | Descriptor: | Galectin-1, beta-D-galactopyranose-(1-4)-methyl 2-acetamido-2-deoxy-beta-D-glucopyranosiduronic acid | Authors: | Lin, H.Y, Hsieh, T.J, Lin, C.H. | Deposit date: | 2015-02-09 | Release date: | 2016-04-06 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | Structural basis of human galectin-1 inhibition with Ki values in the micro- to nanomolar range To Be Published
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4Y1Y
| Complex of human Galectin-1 and (6OSO3)Galbeta1-3GlcNAc | Descriptor: | Galectin-1, beta-D-galactopyranose-(1-3)-methyl 2-acetamido-2-deoxy-6-O-sulfo-beta-D-glucopyranoside | Authors: | Lin, H.Y, Hsieh, T.J, Lin, C.H. | Deposit date: | 2015-02-09 | Release date: | 2016-04-06 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Structural basis of human galectin-1 inhibition with Ki values in the micro- to nanomolar range To Be Published
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4XBL
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4Y20
| Complex of human Galectin-1 and NeuAcalpha2-3Galbeta1-4Glc | Descriptor: | Galectin-1, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Lin, H.Y, Hsieh, T.J, Lin, C.H. | Deposit date: | 2015-02-09 | Release date: | 2016-04-06 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.204 Å) | Cite: | Structural basis of human galectin-1 inhibition with Ki values in the micro- to nanomolar range To Be Published
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5Z19
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5Z1A
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5Z18
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5Z1B
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3O98
| Glutathionylspermidine synthetase/amidase C59A complex with ADP and Gsp | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Bifunctional glutathionylspermidine synthetase/amidase, GLUTATHIONYLSPERMIDINE, ... | Authors: | Pai, C.H, Lin, C.H, Wang, A.H.-J. | Deposit date: | 2010-08-04 | Release date: | 2011-03-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure and mechanism of Escherichia coli glutathionylspermidine amidase belonging to the family of cysteine; histidine-dependent amidohydrolases/peptidases Protein Sci., 20, 2011
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