4Y24
Complex of human Galectin-1 and TD-139
Summary for 4Y24
Entry DOI | 10.2210/pdb4y24/pdb |
Related | 4Y1U 4Y1V 4Y1X 4Y1Y 4Y1Z 4Y20 4Y22 |
Descriptor | Galectin-1, 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-beta-D-galactopyranosyl 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-1-thio-beta-D-galactopyranoside (3 entities in total) |
Functional Keywords | complex, galectin-1, tdg, td-139, sugar binding protein |
Biological source | Homo sapiens (Human) |
Cellular location | Secreted, extracellular space, extracellular matrix : P09382 |
Total number of polymer chains | 2 |
Total formula weight | 34959.20 |
Authors | Lin, H.Y.,Hsieh, T.J.,Lin, C.H. (deposition date: 2015-02-09, release date: 2016-04-27, Last modification date: 2024-03-20) |
Primary citation | Hsieh, T.J.,Lin, H.Y.,Tu, Z.,Lin, T.C.,Wu, S.C.,Tseng, Y.Y.,Liu, F.T.,Hsu, S.T.,Lin, C.H. Dual thio-digalactoside-binding modes of human galectins as the structural basis for the design of potent and selective inhibitors. Sci Rep, 6:29457-29457, 2016 Cited by PubMed: 27416897DOI: 10.1038/srep29457 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.32 Å) |
Structure validation
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