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3UY6
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BU of 3uy6 by Molmil
BlaR1 sensor domain from Staphylococcus aureus with N439V mutation
Descriptor: GLYCEROL, Regulatory protein BlaR1, SULFATE ION
Authors:Baker, B.M, Borbulevych, O.Y.
Deposit date:2011-12-05
Release date:2012-02-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:An amino acid position at crossroads of evolution of protein function: antibiotic sensor domain of BlaR1 protein from Staphylococcus aureus versus clasS D beta-lactamases
J.Biol.Chem., 287, 2012
6AM5
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BU of 6am5 by Molmil
Crystal structure of DMF5 TCR bound to HLA-A2 presenting synthetic peptide SMLGIGIVPV
Descriptor: Beta-2-microglobulin, DMF5 TCR alpha chain, DMF5 TCR beta chain, ...
Authors:Riley, T.P, Baker, B.M.
Deposit date:2017-08-09
Release date:2018-08-08
Method:X-RAY DIFFRACTION (2.394 Å)
Cite:Crystal structure of DMF5 TCR bound to HLA-A2 presenting synthetic peptide SMLGIGIVPV
To Be Published
6PTB
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BU of 6ptb by Molmil
Crystal Structure of ILNAMIAKI peptide bound to HLA-A2
Descriptor: Beta-2-microglobulin, GLYCEROL, HAUS augmin-like complex subunit 3, ...
Authors:Keller, G.L.J, Arbuiso, A, Baker, B.M.
Deposit date:2019-07-15
Release date:2019-09-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structure Based Prediction of Neoantigen Immunogenicity.
Front Immunol, 10, 2019
1DUZ
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BU of 1duz by Molmil
HUMAN CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-A 0201) IN COMPLEX WITH A NONAMERIC PEPTIDE FROM HTLV-1 TAX PROTEIN
Descriptor: BETA-2 MICROGLOBULIN, HLA-A*0201, HTLV-1 OCTAMERIC TAX PEPTIDE
Authors:Khan, A.R, Baker, B.M, Ghosh, P, Biddison, W.E, Wiley, D.C.
Deposit date:2000-01-19
Release date:2000-02-04
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The structure and stability of an HLA-A*0201/octameric tax peptide complex with an empty conserved peptide-N-terminal binding site.
J.Immunol., 164, 2000
1DUY
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BU of 1duy by Molmil
CRYSTAL STRUCTURE OF HLA-A*0201/OCTAMERIC TAX PEPTIDE COMPLEX
Descriptor: BETA-2 MICROGLOBULIN, HLA-A2*0201, HTLV-1 OCTAMERIC TAX PEPTIDE
Authors:Khan, A.R, Baker, B.M, Ghosh, P, Biddison, W.E, Wiley, D.C.
Deposit date:2000-01-19
Release date:2000-02-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The structure and stability of an HLA-A*0201/octameric tax peptide complex with an empty conserved peptide-N-terminal binding site.
J.Immunol., 164, 2000
5JZI
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BU of 5jzi by Molmil
Crystal structure of 1406 TCR bound to HLA-A2 with HCV 1406-1415 antigen peptide
Descriptor: Beta-2-microglobulin, HCV1406 TCR alpha chain, HCV1406 TCR beta chain, ...
Authors:Wang, Y, Piepenbrink, K.H, Baker, B.M.
Deposit date:2016-05-16
Release date:2017-05-31
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:How an alloreactive T-cell receptor achieves peptide and MHC specificity.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
7RRG
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BU of 7rrg by Molmil
Crystal structure of human 0606T1-2 TCR bound to HLA-A*03:01 in complex with a mutant PIK3CA peptide
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Ma, J, Baker, B.M.
Deposit date:2021-08-09
Release date:2022-03-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Immunogenicity and therapeutic targeting of a public neoantigen derived from mutated PIK3CA.
Nat Med, 28, 2022
7RE9
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BU of 7re9 by Molmil
TCR mimic antibody (Fab fragment)
Descriptor: DI(HYDROXYETHYL)ETHER, Fab heavy chain, Fab light chain
Authors:Dasgupta, M, Baker, B.M.
Deposit date:2021-07-12
Release date:2022-07-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:Validation and promise of a TCR mimic antibody for cancer immunotherapy of hepatocellular carcinoma.
Sci Rep, 12, 2022
7RE8
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BU of 7re8 by Molmil
Class I MHC (HLA-A*02) presenting alpha fetoprotein peptide (AFP)
Descriptor: Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, MHC class I antigen, ...
Authors:Dasgupta, M, Baker, B.M.
Deposit date:2021-07-12
Release date:2022-07-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Validation and promise of a TCR mimic antibody for cancer immunotherapy of hepatocellular carcinoma.
Sci Rep, 12, 2022
7RE7
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BU of 7re7 by Molmil
TCR mimic antibody (Fab fragment) in complex with AFP/HLA-A*02
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-2-microglobulin, FORMIC ACID, ...
Authors:Dasgupta, M, Baker, B.M.
Deposit date:2021-07-12
Release date:2022-07-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.547 Å)
Cite:Validation and promise of a TCR mimic antibody for cancer immunotherapy of hepatocellular carcinoma.
Sci Rep, 12, 2022
7RK7
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BU of 7rk7 by Molmil
The complex between TIL 1383i TCR and human Class I MHC HLA-A2 with the bound Tyrosinase(369-377)(N371D) nonameric peptide
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, A alpha chain, ...
Authors:Singh, N.K, Davancaze, L.M, Arbuiso, A, Weiss, L.I, Keller, G.L.J, Baker, B.M.
Deposit date:2021-07-22
Release date:2022-11-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:The complex between TIL 1383i TCR and human Class I MHC HLA-A2 with the bound Tyrosinase(369-377)(N371D) nonameric peptide
To Be Published
1TVH
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BU of 1tvh by Molmil
Crystal structure of Modified Melanoma Antigen gp100(209-T2M) Bound to Human Class I MHC HLA-A2
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2004-06-29
Release date:2005-04-19
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.802 Å)
Cite:Increased Immunogenicity of an Anchor-Modified Tumor-Associated Antigen Is Due to the Enhanced Stability of the Peptide/MHC Complex: Implications for Vaccine Design
J.Immunol., 174, 2005
6OPD
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BU of 6opd by Molmil
Crystal Structure of ILNAMIVKI peptide bound to HLA-A2
Descriptor: ACETATE ION, Beta-2-microglobulin, GLYCEROL, ...
Authors:Davancaze, L.M, Arbuiso, A, Baker, B.M.
Deposit date:2019-04-24
Release date:2019-09-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.791 Å)
Cite:Structure Based Prediction of Neoantigen Immunogenicity.
Front Immunol, 10, 2019
6P64
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BU of 6p64 by Molmil
Alpha-beta TCR Binding to Neoantigen KQWLVWLFL Presented by HLA-A206
Descriptor: 302TIL TCR alpha chain, 302TIL TCR beta chain, Beta-2-microglobulin, ...
Authors:Devlin, J.R, Baker, B.M.
Deposit date:2019-05-31
Release date:2020-06-03
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:A T cell receptor peptide/MHC complex at 3.05 Angstrom resolution
To be Published
6PTE
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BU of 6pte by Molmil
Crystal Structure of ILNAMITKI peptide bound to HLA-A2
Descriptor: Beta-2-microglobulin, GLYCEROL, HAUS augmin-like complex subunit 3, ...
Authors:Smith, A.R, Arbuiso, A, Keller, G.L.J, Baker, B.M.
Deposit date:2019-07-15
Release date:2019-09-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:Structure Based Prediction of Neoantigen Immunogenicity.
Front Immunol, 10, 2019
1TVB
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BU of 1tvb by Molmil
Crystal structure of Melanoma Antigen gp100(209-217) Bound to Human Class I MHC HLA-A2
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2004-06-29
Release date:2005-04-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Increased Immunogenicity of an Anchor-Modified Tumor-Associated Antigen Is Due to the Enhanced Stability of the Peptide/MHC Complex: Implications for Vaccine Design
J.Immunol., 174, 2005
3O3E
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BU of 3o3e by Molmil
Human Class I MHC HLA-A2 in complex with the Peptidomimetic ELA-2.1
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2010-07-23
Release date:2010-12-08
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structures of HLA-A*0201 complexed with Melan-A/MART-1(26(27L)-35) peptidomimetics reveal conformational heterogeneity and highlight degeneracy of T cell recognition.
J.Med.Chem., 53, 2010
3O3B
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BU of 3o3b by Molmil
Human Class I MHC HLA-A2 in complex with the Peptidomimetic ELA-1.1
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2010-07-23
Release date:2010-12-08
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures of HLA-A*0201 complexed with Melan-A/MART-1(26(27L)-35) peptidomimetics reveal conformational heterogeneity and highlight degeneracy of T cell recognition.
J.Med.Chem., 53, 2010
3O3D
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BU of 3o3d by Molmil
Human Class I MHC HLA-A2 in complex with the Peptidomimetic ELA-2
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2010-07-23
Release date:2010-12-08
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structures of HLA-A*0201 complexed with Melan-A/MART-1(26(27L)-35) peptidomimetics reveal conformational heterogeneity and highlight degeneracy of T cell recognition.
J.Med.Chem., 53, 2010
3O3A
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BU of 3o3a by Molmil
Human Class I MHC HLA-A2 in complex with the Peptidomimetic ELA-1
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2010-07-23
Release date:2010-12-08
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structures of HLA-A*0201 complexed with Melan-A/MART-1(26(27L)-35) peptidomimetics reveal conformational heterogeneity and highlight degeneracy of T cell recognition.
J.Med.Chem., 53, 2010
3MYJ
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BU of 3myj by Molmil
Human Class I MHC HLA-A2 in complex with the WT-1 (126-134) (R1Y) peptide variant.
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2010-05-10
Release date:2010-08-18
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structures of native and affinity-enhanced WT1 epitopes bound to HLA-A*0201: Implications for WT1-based cancer therapeutics.
Mol.Immunol., 47, 2010
3PWJ
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BU of 3pwj by Molmil
Human Class I MHC HLA-A2 in complex with the HuD (G2L,I9V) peptide variant
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2010-12-08
Release date:2011-03-09
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Conformational Melding Permits a Conserved Binding Geometry in TCR Recognition of Foreign and Self Molecular Mimics.
J.Immunol., 186, 2011
3PWL
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BU of 3pwl by Molmil
Human Class I MHC HLA-A2 in complex with the HuD peptide
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2010-12-08
Release date:2011-03-09
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Conformational Melding Permits a Conserved Binding Geometry in TCR Recognition of Foreign and Self Molecular Mimics.
J.Immunol., 186, 2011
3PWN
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BU of 3pwn by Molmil
Human Class I MHC HLA-A2 in complex with the HuD (G2L) peptide variant
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2010-12-08
Release date:2011-03-09
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Conformational Melding Permits a Conserved Binding Geometry in TCR Recognition of Foreign and Self Molecular Mimics.
J.Immunol., 186, 2011
3PWP
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BU of 3pwp by Molmil
The complex between TCR A6 and human Class I MHC HLA-A2 with the bound HuD peptide
Descriptor: A6 TCR alpha chain, A6 TCR beta chain, Beta-2-microglobulin, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2010-12-08
Release date:2011-03-09
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Conformational Melding Permits a Conserved Binding Geometry in TCR Recognition of Foreign and Self Molecular Mimics.
J.Immunol., 186, 2011

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數據於2024-10-16公開中

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