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1ECC
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BU of 1ecc by Molmil
ESCHERICHIA COLI GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE (PRPP) AMIDOTRANSFERASE COMPLEXED WITH MN-CPRPP AND 5-OXO-NORLEUCINE
Descriptor: 1-ALPHA-PYROPHOSPHORYL-2-ALPHA,3-ALPHA-DIHYDROXY-4-BETA-CYCLOPENTANE-METHANOL-5-PHOSPHATE, 5-OXO-L-NORLEUCINE, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE, ...
Authors:Krahn, J.M, Smith, J.L.
Deposit date:1997-07-09
Release date:1998-04-15
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Coupled formation of an amidotransferase interdomain ammonia channel and a phosphoribosyltransferase active site.
Biochemistry, 36, 1997
7K93
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BU of 7k93 by Molmil
DENV2 NS1 in complex with neutralizing 2B7 single chain Fab variable region (scFv)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2B7 single chain fab variable region, Non-structural protein 1
Authors:Akey, D.L, Smith, J.L.
Deposit date:2020-09-28
Release date:2020-12-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Structural basis for antibody inhibition of flavivirus NS1-triggered endothelial dysfunction.
Science, 371, 2021
7LO1
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BU of 7lo1 by Molmil
FAD-dependent monooxygenase AfoD from A. nidulans
Descriptor: FAD-dependent monooxygenase afoD, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION
Authors:Rodriguez Benitez, A, Smith, J.L, Narayan, A.R.H.
Deposit date:2021-02-08
Release date:2022-04-27
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Deciphering the evolution of flavin-dependent monooxygenase stereoselectivity using ancestral sequence reconstruction.
Proc.Natl.Acad.Sci.USA, 120, 2023
5THZ
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BU of 5thz by Molmil
Crystal structure of CurJ carbon methyltransferase
Descriptor: CITRATE ANION, CurJ, GLYCEROL, ...
Authors:Skiba, M.A, Smith, J.L.
Deposit date:2016-09-30
Release date:2016-10-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Domain Organization and Active Site Architecture of a Polyketide Synthase C-methyltransferase.
ACS Chem. Biol., 11, 2016
5THY
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BU of 5thy by Molmil
Crystal structure of SeMet-Substituted CurJ carbon methyltransferase
Descriptor: CurJ, OXIDIZED GLUTATHIONE DISULFIDE, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Skiba, M.A, Smith, J.L.
Deposit date:2016-09-30
Release date:2016-10-19
Last modified:2019-12-04
Method:X-RAY DIFFRACTION (2.087 Å)
Cite:Domain Organization and Active Site Architecture of a Polyketide Synthase C-methyltransferase.
ACS Chem. Biol., 11, 2016
5TZ7
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BU of 5tz7 by Molmil
Crystal Structure of CurK Dehydratase D1169N Inactive Mutant
Descriptor: CITRATE ANION, CurK
Authors:Dodge, G.J, Smith, J.L.
Deposit date:2016-11-21
Release date:2017-01-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.648 Å)
Cite:Vinylogous Dehydration by a Polyketide Dehydratase Domain in Curacin Biosynthesis.
J. Am. Chem. Soc., 138, 2016
5TZ6
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BU of 5tz6 by Molmil
Crystal Structure of CurJ Dehydratase H978F Inactive Mutant In Complex with Compound 21
Descriptor: (2E,5R)-5-hydroxy-2-methylhept-2-enoic acid, CurJ
Authors:Dodge, G.J, Smith, J.L.
Deposit date:2016-11-21
Release date:2017-01-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Vinylogous Dehydration by a Polyketide Dehydratase Domain in Curacin Biosynthesis.
J. Am. Chem. Soc., 138, 2016
5TZ5
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BU of 5tz5 by Molmil
Crystal Structure of CurK Dehydratase H996F Inactive Mutant
Descriptor: CurK
Authors:Dodge, G.J, Smith, J.L.
Deposit date:2016-11-21
Release date:2017-01-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.428 Å)
Cite:Vinylogous Dehydration by a Polyketide Dehydratase Domain in Curacin Biosynthesis.
J. Am. Chem. Soc., 138, 2016
5VE4
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BU of 5ve4 by Molmil
Crystal structure of persulfide dioxygenase-rhodanese fusion protein with rhodanese domain inactivating mutation (C314S) from Burkholderia phytofirmans
Descriptor: BpPRF, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Motl, N, Skiba, M.A, Smith, J.L, Banerjee, R.
Deposit date:2017-04-03
Release date:2017-07-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural and biochemical analyses indicate that a bacterial persulfide dioxygenase-rhodanese fusion protein functions in sulfur assimilation.
J. Biol. Chem., 292, 2017
5VE5
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BU of 5ve5 by Molmil
Crystal structure of persulfide dioxygenase rhodanese fusion protein with rhodanese domain inactivating mutation (C314S) from Burkholderia phytofirmans in complex with glutathione
Descriptor: BpPRF, CHLORIDE ION, FE (III) ION, ...
Authors:Motl, N, Skiba, M.A, Smith, J.L, Banerjee, R.
Deposit date:2017-04-03
Release date:2017-07-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural and biochemical analyses indicate that a bacterial persulfide dioxygenase-rhodanese fusion protein functions in sulfur assimilation.
J. Biol. Chem., 292, 2017
1MKB
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BU of 1mkb by Molmil
ESCHERICHIA COLI BETA-HYDROXYDECANOYL THIOL ESTER DEHYDRASE AT PH 5 AND 21 DEGREES C
Descriptor: BETA-HYDROXYDECANOYL THIOL ESTER DEHYDRASE
Authors:Leesong, M.
Deposit date:1996-01-08
Release date:1996-07-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of a dehydratase-isomerase from the bacterial pathway for biosynthesis of unsaturated fatty acids: two catalytic activities in one active site.
Structure, 4, 1996
1MKA
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BU of 1mka by Molmil
E. COLI BETA-HYDROXYDECANOYL THIOL ESTER DEHYDRASE MODIFIED BY ITS CLASSIC MECHANISM-BASED INACTIVATOR, 3-DECYNOYL-N-ACETYL CYSTEAMINE
Descriptor: 2-DECENOYL N-ACETYL CYSTEAMINE, BETA-HYDROXYDECANOYL THIOL ESTER DEHYDRASE
Authors:Leesong, M.
Deposit date:1996-01-08
Release date:1996-07-11
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of a dehydratase-isomerase from the bacterial pathway for biosynthesis of unsaturated fatty acids: two catalytic activities in one active site.
Structure, 4, 1996
2MHR
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BU of 2mhr by Molmil
STRUCTURE OF MYOHEMERYTHRIN IN THE AZIDOMET STATE AT 1.7(SLASH)1.3 ANGSTROMS RESOLUTION
Descriptor: AZIDE ION, MU-OXO-DIIRON, MYOHEMERYTHRIN, ...
Authors:Sheriff, S, Hendrickson, W.A.
Deposit date:1987-04-20
Release date:1987-10-16
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structure of myohemerythrin in the azidomet state at 1.7/1.3 A resolution.
J.Mol.Biol., 197, 1987
1F8N
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BU of 1f8n by Molmil
LIPOXYGENASE-1 (SOYBEAN) AT 100K, NEW REFINEMENT
Descriptor: FE (II) ION, LIPOXYGENASE-1
Authors:Tomchick, D.R, Minor, W, Holman, T.
Deposit date:2000-06-30
Release date:2001-07-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural and functional characterization of second-coordination sphere mutants of soybean lipoxygenase-1.
Biochemistry, 40, 2001
1FGM
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BU of 1fgm by Molmil
LIPOXYGENASE-1 (SOYBEAN) AT 100K, N694H MUTANT
Descriptor: FE (III) ION, SEED LIPOXYGENASE-1
Authors:Tomchick, D.R, Minor, W, Holman, T.R.
Deposit date:2000-07-28
Release date:2001-10-24
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and functional characterization of second-coordination sphere mutants of soybean lipoxygenase-1.
Biochemistry, 40, 2001
1GPM
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BU of 1gpm by Molmil
ESCHERICHIA COLI GMP SYNTHETASE COMPLEXED WITH AMP AND PYROPHOSPHATE
Descriptor: ADENOSINE MONOPHOSPHATE, CITRIC ACID, GMP SYNTHETASE, ...
Authors:Tesmer, J.J.G.
Deposit date:1995-04-04
Release date:1996-01-29
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The crystal structure of GMP synthetase reveals a novel catalytic triad and is a structural paradigm for two enzyme families.
Nat.Struct.Biol., 3, 1996
6MCF
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BU of 6mcf by Molmil
Solution structure of 7SK stem-loop 1 with HIV-1 Tat RNA Binding Domain
Descriptor: 7SK Stem-loop 1 RNA, Protein Tat
Authors:Pham, V.V, D'Souza, V.M.
Deposit date:2018-08-31
Release date:2018-10-31
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:HIV-1 Tat interactions with cellular 7SK and viral TAR RNAs identifies dual structural mimicry.
Nat Commun, 9, 2018
6MCE
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BU of 6mce by Molmil
Solution structure of HIV-1 TAR with Tat RNA Binding Domain
Descriptor: Protein Tat, TAR RNA
Authors:Pham, V.V, D'Souza, V.M.
Deposit date:2018-08-31
Release date:2018-10-31
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:HIV-1 Tat interactions with cellular 7SK and viral TAR RNAs identifies dual structural mimicry.
Nat Commun, 9, 2018
6MCI
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BU of 6mci by Molmil
Solution structure of 7SK stem-loop 1
Descriptor: 7SK RNA
Authors:Pham, V.V, D'Souza, V.M.
Deposit date:2018-08-31
Release date:2018-10-31
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:HIV-1 Tat interactions with cellular 7SK and viral TAR RNAs identifies dual structural mimicry.
Nat Commun, 9, 2018
7T1N
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BU of 7t1n by Molmil
Solution structure of 7SK stem-loop 1 with HEXIM Arginine Rich Motif
Descriptor: HEXIM Arginine Rich Motif, RNA (56-MER)
Authors:Pham, V.V, Gao, M, D'Souza, V.M.
Deposit date:2021-12-02
Release date:2022-09-14
Last modified:2024-05-15
Method:SOLUTION NMR, SOLUTION SCATTERING
Cite:A structure-based mechanism for displacement of the HEXIM adapter from 7SK small nuclear RNA.
Commun Biol, 5, 2022
7T1O
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BU of 7t1o by Molmil
Solution structure of 7SK stem-loop 1 with HIV-1 Tat Subtype G Arginine Rich Motif
Descriptor: 7SK stem-loop 1 RNA (56-MER), Tat Subtype G Arginine Rich Motif
Authors:Pham, V.V, Gao, M, D'Souza, V.M.
Deposit date:2021-12-02
Release date:2022-09-14
Last modified:2024-05-15
Method:SOLUTION NMR, SOLUTION SCATTERING
Cite:A structure-based mechanism for displacement of the HEXIM adapter from 7SK small nuclear RNA.
Commun Biol, 5, 2022
7T1P
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BU of 7t1p by Molmil
Solution structure of 7SK stem-loop 1 with HIV-1 Tat Finland Arginine Rich Motif
Descriptor: RNA (56-MER), Tat Finland Arginine Rich Motif
Authors:Pham, V.V, Gao, M, D'Souza, V.M.
Deposit date:2021-12-02
Release date:2022-09-14
Last modified:2024-05-15
Method:SOLUTION NMR, SOLUTION SCATTERING
Cite:A structure-based mechanism for displacement of the HEXIM adapter from 7SK small nuclear RNA.
Commun Biol, 5, 2022
3EOC
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BU of 3eoc by Molmil
Cdk2/CyclinA complexed with a imidazo triazin-2-amine
Descriptor: 5-methyl-7-phenyl-N-(3,4,5-trimethoxyphenyl)imidazo[5,1-f][1,2,4]triazin-2-amine, Cell division protein kinase 2, Cyclin-A2
Authors:Cheung, M, Kuntz, K, Pobanz, M, Salovich, J, Wilson, B, Andrews, W, Shewchuk, L, Epperly, A, Hassler, D, Leesnitzer, M, Smith, J, Smith, G, Lansing, T, Mook, R.
Deposit date:2008-09-26
Release date:2008-11-04
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Imidazo[5,1-f][1,2,4]triazin-2-amines as novel inhibitors of polo-like kinase 1.
Bioorg.Med.Chem.Lett., 18, 2008
7ZHO
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BU of 7zho by Molmil
Crystal structure of TTBK1 in complex with compound 3 (7-001)
Descriptor: 1,2-ETHANEDIOL, 4-[3-(2-azanylpyrimidin-4-yl)-1~{H}-indol-5-yl]-2-methyl-but-3-yn-2-ol, PHOSPHATE ION, ...
Authors:Chaikuad, A, Axtman, A, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2022-04-06
Release date:2023-04-19
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Modulation of tau tubulin kinases (TTBK1 and TTBK2) impacts ciliogenesis.
Sci Rep, 13, 2023
7ZHN
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BU of 7zhn by Molmil
Crystal structure of TTBK1 in complex with AMG28
Descriptor: 1,2-ETHANEDIOL, 4-(2-amino-5,6,7,8-tetrahydropyrimido[4',5':3,4]cyclohepta[1,2-b]indol-11-yl)-2-methylbut-3-yn-2-ol, PHOSPHATE ION, ...
Authors:Chaikuad, A, Axtman, A, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2022-04-06
Release date:2023-04-19
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Modulation of tau tubulin kinases (TTBK1 and TTBK2) impacts ciliogenesis.
Sci Rep, 13, 2023

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數據於2024-06-12公開中

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