Solution structure of 7SK stem-loop 1 with HIV-1 Tat RNA Binding Domain

Summary for 6MCF

Descriptor7SK Stem-loop 1 RNA, Protein Tat (2 entities in total)
Functional Keywordstranscription, rna binding domain, rna binding protein
Biological sourceHomo sapiens (Human)
Total number of polymer chains2
Total molecular weight20521.44
Pham, V.V.,D'Souza, V.M. (deposition date: 2018-08-31, release date: 2018-10-31, Last modification date: 2019-11-20)
Primary citation
Pham, V.V.,Salguero, C.,Khan, S.N.,Meagher, J.L.,Brown, W.C.,Humbert, N.,de Rocquigny, H.,Smith, J.L.,D'Souza, V.M.
HIV-1 Tat interactions with cellular 7SK and viral TAR RNAs identifies dual structural mimicry.
Nat Commun, 9:4266-4266, 2018
PubMed: 30323330 (PDB entries with the same primary citation)
DOI: 10.1038/s41467-018-06591-6
MImport into Mendeley
Experimental method
NMR Information

Structure validation

ClashscoreRamachandran outliersSidechain outliersRNA backbone00 1.4% 0.49MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures
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