6MCF

Solution structure of 7SK stem-loop 1 with HIV-1 Tat RNA Binding Domain

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0001070	molecular_function	RNA-binding transcription regulator activity
B	0042025	cellular_component	host cell nucleus
B	0050434	biological_process	positive regulation of viral transcription

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	Motif: {"description":"Nuclear localization signal, RNA-binding (TAR), and protein transduction","evidences":[{"source":"HAMAP-Rule","id":"MF_04079","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	11
Details	Compositional bias: {"description":"Basic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine; by host EP300 and GCN5L2","evidences":[{"source":"HAMAP-Rule","id":"MF_04079","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"18480452","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	2
Details	Modified residue: {"description":"Asymmetric dimethylarginine; by host PRMT6","evidences":[{"source":"HAMAP-Rule","id":"MF_04079","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"17267505","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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