3HVT
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![BU of 3hvt by Molmil](/molmil-images/mine/3hvt) | STRUCTURAL BASIS OF ASYMMETRY IN THE HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 REVERSE TRANSCRIPTASE HETERODIMER | Descriptor: | 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, HIV-1 REVERSE TRANSCRIPTASE (SUBUNIT P51), HIV-1 REVERSE TRANSCRIPTASE (SUBUNIT P66) | Authors: | Steitz, T.A, Smerdon, S.J, Jaeger, J, Wang, J, Kohlstaedt, L.A, Chirino, A.J, Friedman, J.M, Rice, P.A. | Deposit date: | 1994-07-25 | Release date: | 1994-10-15 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure of the binding site for nonnucleoside inhibitors of the reverse transcriptase of human immunodeficiency virus type 1. Proc.Natl.Acad.Sci.Usa, 91, 1994
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3AH5
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![BU of 3ah5 by Molmil](/molmil-images/mine/3ah5) | Crystal Structure of flavin dependent thymidylate synthase ThyX from helicobacter pylori complexed with FAD and dUMP | Descriptor: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, ... | Authors: | Zhang, X, Zhang, J, Hu, Y, Zou, Q, Wang, D. | Deposit date: | 2010-04-14 | Release date: | 2011-04-20 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure and functional analysis of a flavin dependent thymidylate synthase from helicobacter pylori To be Published
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5ITU
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![BU of 5itu by Molmil](/molmil-images/mine/5itu) | Crystal Structure of Human NEIL1(242K) bound to duplex DNA containing THF | Descriptor: | DNA (5'-D(*CP*GP*TP*CP*CP*AP*CP*GP*TP*CP*TP*AP*C)-3'), DNA (5'-D(*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*G)-3'), Endonuclease 8-like 1 | Authors: | Zhu, C, Lu, L, Zhang, J, Yue, Z, Song, J, Zong, S, Liu, M, Stovicek, O, Gao, Y, Yi, C. | Deposit date: | 2016-03-17 | Release date: | 2016-07-06 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Tautomerization-dependent recognition and excision of oxidation damage in base-excision DNA repair Proc.Natl.Acad.Sci.USA, 113, 2016
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5ITT
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![BU of 5itt by Molmil](/molmil-images/mine/5itt) | Crystal Structure of Human NEIL1 bound to duplex DNA containing THF | Descriptor: | DNA (26-MER), Endonuclease 8-like 1, GLYCEROL | Authors: | Zhu, C, Lu, L, Zhang, J, Yue, Z, Song, J, Zong, S, Liu, M, Stovicek, O, Gao, Y, Yi, C. | Deposit date: | 2016-03-17 | Release date: | 2016-07-06 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.53 Å) | Cite: | Tautomerization-dependent recognition and excision of oxidation damage in base-excision DNA repair Proc.Natl.Acad.Sci.USA, 113, 2016
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2AOR
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![BU of 2aor by Molmil](/molmil-images/mine/2aor) | Crystal structure of MutH-hemimethylated DNA complex | Descriptor: | 5'-D(*CP*AP*GP*GP*(6MA)P*TP*CP*CP*AP*AP*GP*CP*TP*TP*GP*GP*AP*TP*CP*CP*TP*G)-3', CALCIUM ION, DNA mismatch repair protein mutH | Authors: | Lee, J.Y, Chang, J, Joseph, N, Ghirlando, R, Rao, D.N, Yang, W. | Deposit date: | 2005-08-13 | Release date: | 2005-10-11 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | MutH complexed with hemi- and unmethylated DNAs: coupling base recognition and DNA cleavage. Mol.Cell, 20, 2005
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3NAE
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![BU of 3nae by Molmil](/molmil-images/mine/3nae) | RB69 DNA Polymerase (Y567A) Ternary Complex with dATP Opposite Guanidinohydantoin | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ... | Authors: | Wang, M, Beckman, J, Blaha, G, Wang, J, Konigsberg, W.H. | Deposit date: | 2010-06-01 | Release date: | 2010-09-15 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.003 Å) | Cite: | Substitution of Ala for Tyr567 in RB69 DNA Polymerase Allows dAMP and dGMP To Be Inserted opposite Guanidinohydantoin . Biochemistry, 49, 2010
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6MWY
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![BU of 6mwy by Molmil](/molmil-images/mine/6mwy) | The Prp8 intein of Cryptococcus gattii | Descriptor: | Pre-mRNA-processing-splicing factor 8 | Authors: | Li, Z, Fu, B, Green, C.M, Lang, Y, Zhang, J, Oven, T.S, Li, X, Callahan, B.P, Chaturvedi, S, Belfort, M, Liao, G, Li, H. | Deposit date: | 2018-10-30 | Release date: | 2019-11-06 | Last modified: | 2020-05-20 | Method: | X-RAY DIFFRACTION (2.594 Å) | Cite: | Cisplatin protects mice from challenge ofCryptococcus neoformansby targeting the Prp8 intein. Emerg Microbes Infect, 8, 2019
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3TYH
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![BU of 3tyh by Molmil](/molmil-images/mine/3tyh) | Crystal structure of oxo-cupper clusters binding to ferric binding protein from Neisseria gonorrhoeae | Descriptor: | COPPER (II) ION, FbpA protein | Authors: | Chen, W.J, Wang, H.F, Zhou, C.J, Ye, D.R, Huang, J, Tan, X.S, Zhong, W.Q. | Deposit date: | 2011-09-26 | Release date: | 2012-09-26 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of oxo-cupper clusters binding to ferric binding protein from Neisseria gonorrhoeae To be Published
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2JXW
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![BU of 2jxw by Molmil](/molmil-images/mine/2jxw) | |
2KU3
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![BU of 2ku3 by Molmil](/molmil-images/mine/2ku3) | |
5U73
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![BU of 5u73 by Molmil](/molmil-images/mine/5u73) | Crystal structure of human Niemann-Pick C1 protein | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Niemann-Pick C1 protein, ... | Authors: | Li, X, Wang, J, Blobel, G. | Deposit date: | 2016-12-11 | Release date: | 2017-09-27 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.348 Å) | Cite: | 3.3 angstrom structure of Niemann-Pick C1 protein reveals insights into the function of the C-terminal luminal domain in cholesterol transport. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5TW2
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![BU of 5tw2 by Molmil](/molmil-images/mine/5tw2) | Structure of mouse CD1d with bound alpha-galactosylsphingamide JG168 | Descriptor: | (5R,6S,7S)-5,6-dihydroxy-7-(octanoylamino)-N-(6-phenylhexyl)-8-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}octanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Zajonc, D.M, Wang, J. | Deposit date: | 2016-11-11 | Release date: | 2017-09-20 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Galactosylsphingamides: new alpha-GalCer analogues to probe the F'-pocket of CD1d. Sci Rep, 7, 2017
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5MV2
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![BU of 5mv2 by Molmil](/molmil-images/mine/5mv2) | Crystal structure of the E protein of the Japanese encephalitis live attenuated vaccine virus | Descriptor: | E protein | Authors: | Liu, X, Zhao, X, Na, R, Li, L, Warkentin, E, Witt, J, Lu, X, Wei, Y, Peng, G, Li, Y, Wang, J. | Deposit date: | 2017-01-14 | Release date: | 2018-05-23 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The structure differences of Japanese encephalitis virus SA14 and SA14-14-2 E proteins elucidate the virulence attenuation mechanism. Protein Cell, 10, 2019
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8HQI
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![BU of 8hqi by Molmil](/molmil-images/mine/8hqi) | |
8HQH
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![BU of 8hqh by Molmil](/molmil-images/mine/8hqh) | |
8HQJ
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![BU of 8hqj by Molmil](/molmil-images/mine/8hqj) | |
3KD7
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![BU of 3kd7 by Molmil](/molmil-images/mine/3kd7) | |
2L43
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![BU of 2l43 by Molmil](/molmil-images/mine/2l43) | Structural basis for histone code recognition by BRPF2-PHD1 finger | Descriptor: | Histone H3.3,LINKER,Bromodomain-containing protein 1, ZINC ION | Authors: | Qin, S, Zhang, J, Wu, J, Shi, Y. | Deposit date: | 2010-10-01 | Release date: | 2011-08-31 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Recognition of unmodified histone H3 by the first PHD finger of Bromodomain-PHD finger protein 2 provides insights into the regulation of histone acetyltransferases MOZ and MORF To be Published
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8HQF
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![BU of 8hqf by Molmil](/molmil-images/mine/8hqf) | |
5MV1
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![BU of 5mv1 by Molmil](/molmil-images/mine/5mv1) | Crystal structure of the E protein of the Japanese encephalitis virulent virus | Descriptor: | E protein | Authors: | Liu, X, Zhao, X, Na, R, Li, L, Warkentin, E, Witt, J, Lu, X, Wei, Y, Peng, G, Li, Y, Wang, J. | Deposit date: | 2017-01-14 | Release date: | 2018-05-23 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | The structure differences of Japanese encephalitis virus SA14 and SA14-14-2 E proteins elucidate the virulence attenuation mechanism. Protein Cell, 10, 2019
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2L42
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4IFP
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![BU of 4ifp by Molmil](/molmil-images/mine/4ifp) | X-ray Crystal Structure of Human NLRP1 CARD Domain | Descriptor: | MALONATE ION, Maltose-binding periplasmic protein,NACHT, LRR and PYD domains-containing protein 1, ... | Authors: | Jin, T, Curry, J, Smith, P, Jiang, J, Xiao, T. | Deposit date: | 2012-12-14 | Release date: | 2013-04-03 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.9948 Å) | Cite: | Structure of the NLRP1 caspase recruitment domain suggests potential mechanisms for its association with procaspase-1. Proteins, 81, 2013
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2L7E
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![BU of 2l7e by Molmil](/molmil-images/mine/2l7e) | |
1DDJ
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![BU of 1ddj by Molmil](/molmil-images/mine/1ddj) | CRYSTAL STRUCTURE OF HUMAN PLASMINOGEN CATALYTIC DOMAIN | Descriptor: | PLASMINOGEN | Authors: | Wang, X, Terzyan, S, Tang, J, Loy, J, Lin, X, Zhang, X. | Deposit date: | 1999-11-10 | Release date: | 2000-02-18 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Human plasminogen catalytic domain undergoes an unusual conformational change upon activation. J.Mol.Biol., 295, 2000
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8HVL
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![BU of 8hvl by Molmil](/molmil-images/mine/8hvl) | Crystal structure of SARS-Cov-2 main protease M49I mutant in complex with PF07321332 | Descriptor: | (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, 3C-like proteinase nsp5 | Authors: | Zou, X.F, Zhang, J, Li, J. | Deposit date: | 2022-12-27 | Release date: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Crystal structure of SARS-Cov-2 main protease
M49I mutant in complex with PF07321332 To Be Published
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