8TGH
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![BU of 8tgh by Molmil](/molmil-images/mine/8tgh) | VMAT1 dimer with amphetamine and reserpine | Descriptor: | (2S)-1-phenylpropan-2-amine, Chromaffin granule amine transporter, reserpine | Authors: | Ye, J, Liu, B, Li, W. | Deposit date: | 2023-07-12 | Release date: | 2024-03-20 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural insights into vesicular monoamine storage and drug interactions. Nature, 629, 2024
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8TGG
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![BU of 8tgg by Molmil](/molmil-images/mine/8tgg) | VMAT1 dimer with MPP+ and reserpine | Descriptor: | 1-methyl-4-phenylpyridin-1-ium, Chromaffin granule amine transporter, reserpine | Authors: | Ye, J, Liu, B, Li, W. | Deposit date: | 2023-07-12 | Release date: | 2024-03-20 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural insights into vesicular monoamine storage and drug interactions. Nature, 629, 2024
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8TGL
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![BU of 8tgl by Molmil](/molmil-images/mine/8tgl) | VMAT1 dimer with norepinephrine and reserpine | Descriptor: | Chromaffin granule amine transporter, L-NOREPINEPHRINE, reserpine | Authors: | Ye, J, Liu, B, Li, W. | Deposit date: | 2023-07-12 | Release date: | 2024-03-20 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural insights into vesicular monoamine storage and drug interactions. Nature, 629, 2024
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8TGM
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![BU of 8tgm by Molmil](/molmil-images/mine/8tgm) | VMAT1 dimer with reserpine | Descriptor: | VMAT1 dimer with reserpine, reserpine | Authors: | Ye, J, Liu, B, Li, W. | Deposit date: | 2023-07-12 | Release date: | 2024-03-20 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural insights into vesicular monoamine storage and drug interactions. Nature, 629, 2024
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8TGI
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![BU of 8tgi by Molmil](/molmil-images/mine/8tgi) | VMAT1 dimer with dopamine and reserpine | Descriptor: | Chromaffin granule amine transporter, L-DOPAMINE, reserpine | Authors: | Ye, J, Liu, B, Li, W. | Deposit date: | 2023-07-12 | Release date: | 2024-03-20 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural insights into vesicular monoamine storage and drug interactions. Nature, 629, 2024
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8TGJ
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![BU of 8tgj by Molmil](/molmil-images/mine/8tgj) | VMAT1 dimer in unbound form and with reserpine | Descriptor: | VMAT1 dimer in unbound form and with reserpine, reserpine | Authors: | Ye, J, Liu, B, Li, W. | Deposit date: | 2023-07-12 | Release date: | 2024-03-20 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural insights into vesicular monoamine storage and drug interactions. Nature, 629, 2024
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8TGK
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![BU of 8tgk by Molmil](/molmil-images/mine/8tgk) | VMAT1 dimer with histamine and reserpine | Descriptor: | Chromaffin granule amine transporter, HISTAMINE, reserpine | Authors: | Ye, J, Liu, B, Li, W. | Deposit date: | 2023-07-12 | Release date: | 2024-03-20 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural insights into vesicular monoamine storage and drug interactions. Nature, 629, 2024
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1YUK
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![BU of 1yuk by Molmil](/molmil-images/mine/1yuk) | The crystal structure of the PSI/Hybrid domain/ I-EGF1 segment from the human integrin beta2 at 1.8 resolution | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, Integrin beta-2 A chain, Integrin beta-2 B chain | Authors: | Shi, M, Sundramurthy, K, Liu, B, Tan, S.M, Law, S.K, Lescar, J. | Deposit date: | 2005-02-14 | Release date: | 2005-07-19 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The Crystal Structure of the Plexin-Semaphorin-Integrin Domain/Hybrid Domain/I-EGF1 Segment from the Human Integrin {beta}2 Subunit at 1.8-A Resolution J.Biol.Chem., 280, 2005
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7TGY
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![BU of 7tgy by Molmil](/molmil-images/mine/7tgy) | Prototypic SARS-CoV-2 G614 spike (closed form) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | Authors: | Ye, G, Liu, B, Li, F. | Deposit date: | 2022-01-09 | Release date: | 2022-03-09 | Last modified: | 2022-03-16 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Cryo-EM structure of a SARS-CoV-2 omicron spike protein ectodomain. Nat Commun, 13, 2022
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7TGX
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![BU of 7tgx by Molmil](/molmil-images/mine/7tgx) | Prototypic SARS-CoV-2 G614 spike (open form) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, alpha-D-mannopyranose, ... | Authors: | Ye, G, Liu, B, Li, F. | Deposit date: | 2022-01-09 | Release date: | 2022-03-09 | Last modified: | 2022-03-16 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-EM structure of a SARS-CoV-2 omicron spike protein ectodomain. Nat Commun, 13, 2022
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7TGW
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![BU of 7tgw by Molmil](/molmil-images/mine/7tgw) | Omicron spike at 3.0 A (open form) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | Authors: | Ye, G, Liu, B, Li, F. | Deposit date: | 2022-01-09 | Release date: | 2022-03-09 | Last modified: | 2022-03-16 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Cryo-EM structure of a SARS-CoV-2 omicron spike protein ectodomain. Nat Commun, 13, 2022
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3OMV
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![BU of 3omv by Molmil](/molmil-images/mine/3omv) | Crystal structure of c-raf (raf-1) | Descriptor: | (1E)-5-(1-piperidin-4-yl-3-pyridin-4-yl-1H-pyrazol-4-yl)-2,3-dihydro-1H-inden-1-one oxime, RAF proto-oncogene serine/threonine-protein kinase | Authors: | Hatzivassiliou, G, Song, K, Yen, I, Brandhuber, B.J, Anderson, D.J, Alvarado, R, Ludlam, M.J, Stokoe, D, Gloor, S.L, Vigers, G.P.A, Morales, T, Aliagas, I, Liu, B, Sideris, S, Hoeflich, K.P, Jaiswal, B.S, Seshagiri, S, Koeppen, H, Belvin, M, Friedman, L.S, Malek, S. | Deposit date: | 2010-08-27 | Release date: | 2010-09-15 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth. Nature, 464, 2010
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8G7B
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![BU of 8g7b by Molmil](/molmil-images/mine/8g7b) | |
8G76
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![BU of 8g76 by Molmil](/molmil-images/mine/8g76) | SARS-CoV-2 spike/Nb5 complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanosota-5, ... | Authors: | Ye, G, Bu, F, Liu, B, Li, F. | Deposit date: | 2023-02-16 | Release date: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | SARS-CoV-2 spike/Nb5 complex To Be Published
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8G77
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![BU of 8g77 by Molmil](/molmil-images/mine/8g77) | SARS-CoV-2 spike/Nb6 complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanosota-6, ... | Authors: | Ye, G, Bu, F, Liu, B, Li, F. | Deposit date: | 2023-02-16 | Release date: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | SARS-CoV-2 spike/Nb6 complex To Be Published
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8G7A
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![BU of 8g7a by Molmil](/molmil-images/mine/8g7a) | |
8G7C
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![BU of 8g7c by Molmil](/molmil-images/mine/8g7c) | |
8G70
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![BU of 8g70 by Molmil](/molmil-images/mine/8g70) | SARS-CoV-2 spike/nanobody mixture complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanosota-3, ... | Authors: | Ye, G, Bu, F, Liu, B, Li, F. | Deposit date: | 2023-02-16 | Release date: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | SARS-CoV-2 spike/nanobody mixture complex To Be Published
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8G78
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![BU of 8g78 by Molmil](/molmil-images/mine/8g78) | Local refinement of SARS-CoV-2 spike/nanobody mixture complex around NTD | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Nanosota-5, Nanosota-6, ... | Authors: | Ye, G, Bu, F, Liu, B, Li, F. | Deposit date: | 2023-02-16 | Release date: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Local refinement of SARS-CoV-2 spike/nanobody mixture complex around NTD To Be Published
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8G72
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![BU of 8g72 by Molmil](/molmil-images/mine/8g72) | SARS-CoV-2 spike/Nb2 complex with 1 RBD up (local refinement at 5.6 A) | Descriptor: | Nanosota-2, Spike glycoprotein | Authors: | Ye, G, Bu, F, Liu, B, Li, F. | Deposit date: | 2023-02-16 | Release date: | 2024-01-24 | Method: | ELECTRON MICROSCOPY (5.6 Å) | Cite: | Discovery of Nanosota-2, -3, and -4 as super potent and broad-spectrum therapeutic nanobody candidates against COVID-19. J.Virol., 97, 2023
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8G74
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![BU of 8g74 by Molmil](/molmil-images/mine/8g74) | SARS-CoV-2 spike/Nb3 complex with 1 RBD up and 2 Nb3 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanosota-3, ... | Authors: | Ye, G, Bu, F, Liu, B, Li, F. | Deposit date: | 2023-02-16 | Release date: | 2024-01-24 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Discovery of Nanosota-2, -3, and -4 as super potent and broad-spectrum therapeutic nanobody candidates against COVID-19. J.Virol., 97, 2023
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8G73
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![BU of 8g73 by Molmil](/molmil-images/mine/8g73) | SARS-CoV-2 spike/Nb3 complex with 2 RBDs up and 3 Nb3 bound at 2.5 A | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanosota-3, ... | Authors: | Ye, G, Bu, F, Liu, B, Li, F. | Deposit date: | 2023-02-16 | Release date: | 2024-01-24 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Discovery of Nanosota-2, -3, and -4 as super potent and broad-spectrum therapeutic nanobody candidates against COVID-19. J.Virol., 97, 2023
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8G75
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![BU of 8g75 by Molmil](/molmil-images/mine/8g75) | SARS-CoV-2 spike/Nb4 complex with 2 RBDs up and 3 Nb4 bound | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanosota-4, ... | Authors: | Ye, G, Bu, F, Liu, B, Li, F. | Deposit date: | 2023-02-16 | Release date: | 2024-01-24 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Discovery of Nanosota-2, -3, and -4 as super potent and broad-spectrum therapeutic nanobody candidates against COVID-19. J.Virol., 97, 2023
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8G71
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![BU of 8g71 by Molmil](/molmil-images/mine/8g71) | Spike/Nb2 complex with 1 RBD up | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | Authors: | Ye, G, Bu, F, Liu, B, Li, F. | Deposit date: | 2023-02-16 | Release date: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (2.1 Å) | Cite: | SARS-CoV-2 spike/Nb2 complex with 1 RBD up To Be Published
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8G79
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![BU of 8g79 by Molmil](/molmil-images/mine/8g79) | |