3ROM
 
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3U31
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3ROP
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3U3D
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5B7B
 | | Crystal structure of Nucleoprotein-nucleozin complex | | Descriptor: | Nucleoprotein, [4-(2-chloro-4-nitrophenyl)piperazin-1-yl](5-methyl-3-phenyl-1,2-oxazol-4-yl)methanone | | Authors: | Pang, B, Zhang, W.Z, Zhang, H.M, Hao, Q. | | Deposit date: | 2016-06-06 | | Release date: | 2016-07-06 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural Characterization of H1N1 Nucleoprotein-Nucleozin Binding Sites
Sci Rep, 6, 2016
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5BNI
 | | Porcine CD38 complexed with complexed with a covalent intermediate, ribo-F-ribose-5'-phosphate | | Descriptor: | Uncharacterized protein, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl [(2R,3R,4S)-4-fluoro-3-hydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate | | Authors: | Ting, K.Y, Leung, C.F.P, Graeff, R.M, Lee, H.C, Hao, Q, Kotaka, M. | | Deposit date: | 2015-05-26 | | Release date: | 2016-05-25 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Porcine CD38 exhibits prominent secondary NAD(+) cyclase activity.
Protein Sci., 25, 2016
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5CSD
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5BNF
 | | Apo structure of porcine CD38 | | Descriptor: | Uncharacterized protein | | Authors: | Ting, K.Y, Leung, C.P.F, Graeff, R.M, Lee, H.C, Hao, Q, Kotaka, M. | | Deposit date: | 2015-05-26 | | Release date: | 2016-05-25 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Porcine CD38 exhibits prominent secondary NAD(+) cyclase activity.
Protein Sci., 25, 2016
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5E7X
 | | Ligand binding domain 1 of Penicillium marneffei MP1 protein in complex with palmitic acid | | Descriptor: | ACETATE ION, Cell wall antigen, GLYCEROL, ... | | Authors: | Lam, W.H, Zhang, H, Hao, Q. | | Deposit date: | 2015-10-13 | | Release date: | 2016-10-19 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Talaromyces marneffeiMp1 protein, a novel virulence factor, carries two arachidonic acid-binding domains to suppress inflammatory responses in hosts.
Infect. Immun., 2019
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4H0W
 | | Bismuth bound human serum transferrin | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Bismuth(III) ION, CARBONATE ION, ... | | Authors: | Yang, N, Zhang, H, Wang, M, Hao, Q, Sun, H. | | Deposit date: | 2012-09-10 | | Release date: | 2012-12-26 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Iron and bismuth bound human serum transferrin reveals a partially-opened conformation in the N-lobe.
Sci Rep, 2, 2012
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6ISO
 | | Human SIRT3 Recognizing H3K4cr | | Descriptor: | (2E)-BUT-2-ENAL, ARG-THR-LYS-GLN-THR-ALA-ARG, GLYCEROL, ... | | Authors: | Wang, Y, Hao, Q. | | Deposit date: | 2018-11-17 | | Release date: | 2019-01-23 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.95 Å) | | Cite: | Identification of 'erasers' for lysine crotonylated histone marks using a chemical proteomics approach.
Elife, 3, 2014
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6J6F
 | | Ligand binding domain 1 and 2 of Talaromyces marneffei Mp1 protein | | Descriptor: | Envelope glycoprotein, NICKEL (II) ION | | Authors: | Lam, W.H, Zhang, H, Hao, Q. | | Deposit date: | 2019-01-15 | | Release date: | 2019-03-06 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (4.2 Å) | | Cite: | Talaromyces marneffeiMp1 Protein, a Novel Virulence Factor, Carries Two Arachidonic Acid-Binding Domains To Suppress Inflammatory Responses in Hosts.
Infect. Immun., 87, 2019
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6J1U
 | | influenza virus nucleoprotein with a specific inhibitor | | Descriptor: | Nucleoprotein, ~{N}-[4-[(4-~{tert}-butylphenyl)carbonylamino]phenyl]-2,3-dihydro-1,4-benzodioxine-6-carboxamide | | Authors: | Pang, B, Zhang, W.Z, Zhang, H.M, Hao, Q. | | Deposit date: | 2018-12-29 | | Release date: | 2020-01-01 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Discovery of a Novel Specific Inhibitor Targeting Influenza A Virus Nucleoprotein with Pleiotropic Inhibitory Effects on Various Steps of the Viral Life Cycle.
J.Virol., 95, 2021
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8GCR
 | | HPV16 E6-E6AP-p53 complex | | Descriptor: | Cellular tumor antigen p53, Maltose/maltodextrin-binding periplasmic protein,Protein E6, Ubiquitin-protein ligase E3A, ... | | Authors: | Bratkowski, M.A, Wang, J.C.K, Hao, Q, Nile, A.H. | | Deposit date: | 2023-03-02 | | Release date: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.38 Å) | | Cite: | Structure of the p53 degradation complex from HPV16.
Nat Commun, 15, 2024
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5Y8V
 | | Crystal structure of GAS41 | | Descriptor: | MAGNESIUM ION, YEATS domain-containing protein 4 | | Authors: | Wang, Y, Hao, Q. | | Deposit date: | 2017-08-21 | | Release date: | 2018-04-25 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.61 Å) | | Cite: | Identification of the YEATS domain of GAS41 as a pH-dependent reader of histone succinylation
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5ZJC
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5WYI
 | | The Yaf9 YEATS domain Recognizing H3K122suc Peptide | | Descriptor: | (2S)-2-azanyl-6-[(4-hydroxy-4-oxo-butanoyl)amino]hexanoic acid, ILE-MET-PRO-LYS-ASP-ILE-GLN-LEU, SUCCINIC ACID, ... | | Authors: | Wang, Y, Hao, Q. | | Deposit date: | 2017-01-13 | | Release date: | 2018-01-17 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The Yaf9 YEATS domain Recognizing H3K122suc Peptide
To Be Published
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5ZJ1
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5ZJ2
 | | Crystal structure of NDM-1 in complex with D-captopril | | Descriptor: | 1-(3-MERCAPTO-2-METHYL-PROPIONYL)-PYRROLIDINE-2-CARBOXYLIC ACID, Metallo-beta-lactamase type 2, ZINC ION | | Authors: | Zhang, H, Hao, Q. | | Deposit date: | 2018-03-18 | | Release date: | 2019-03-20 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | Structure-guided optimization of D-captopril for discovery of potent NDM-1 inhibitors
Bioorg.Med.Chem., 29, 2020
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5ZIO
 | | Crystal structure of NDM-1 in complex with L-captopril | | Descriptor: | L-CAPTOPRIL, Metallo-beta-lactamase type 2, ZINC ION | | Authors: | Zhang, H, Hao, Q. | | Deposit date: | 2018-03-16 | | Release date: | 2019-03-20 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (0.98 Å) | | Cite: | Structure-guided optimization of D-captopril for discovery of potent NDM-1 inhibitors
Bioorg.Med.Chem., 29, 2020
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5ZJ8
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5ZJ7
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8HLY
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8HLW
 | | Crystal structure of SIRT3 in complex with H4K16la peptide | | Descriptor: | (2S)-2-HYDROXYPROPANOIC ACID, Histone H4 residues 20-27, NAD-dependent protein deacetylase sirtuin-3, ... | | Authors: | Zhuming, F, Hao, Q. | | Deposit date: | 2022-12-01 | | Release date: | 2023-09-27 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Identification of SIRT3 as an eraser of H4K16la.
Iscience, 26, 2023
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1GA5
 | | CRYSTAL STRUCTURE OF THE ORPHAN NUCLEAR RECEPTOR REV-ERB(ALPHA) DNA-BINDING DOMAIN BOUND TO ITS COGNATE RESPONSE ELEMENT | | Descriptor: | 5'-D(*CP*AP*AP*CP*TP*AP*GP*GP*TP*CP*AP*CP*TP*AP*GP*GP*TP*CP*AP*G)-3', 5'-D(*CP*TP*GP*AP*CP*CP*TP*AP*GP*TP*GP*AP*CP*CP*TP*AP*GP*TP*(5IT)P*G)-3', ORPHAN NUCLEAR RECEPTOR NR1D1, ... | | Authors: | Sierk, M.L, Zhao, Q, Rastinejad, F. | | Deposit date: | 2000-11-29 | | Release date: | 2001-11-16 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | DNA Deformability as a Recognition Feature in the RevErb Response Element
Biochemistry, 40, 2001
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