7DX8
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![BU of 7dx8 by Molmil](/molmil-images/mine/7dx8) | Trypsin-digested S protein of SARS-CoV-2 bound with PD of ACE2 in the conformation 2 (2 up RBD and 2 PD bound) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | Authors: | Yan, R.H, Zhang, Y.Y, Li, Y.N, Ye, F.F, Guo, Y.Y, Xia, L, Zhong, X.Y, Chi, X.M, Zhou, Q. | Deposit date: | 2021-01-18 | Release date: | 2021-03-31 | Last modified: | 2021-06-16 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural basis for the different states of the spike protein of SARS-CoV-2 in complex with ACE2. Cell Res., 31, 2021
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7DX5
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![BU of 7dx5 by Molmil](/molmil-images/mine/7dx5) | S protein of SARS-CoV-2 bound with PD of ACE2 in the conformation 2 (1 up RBD and 1 PD bound) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | Authors: | Yan, R.H, Zhang, Y.Y, Li, Y.N, Ye, F.F, Guo, Y.Y, Xia, L, Zhong, X.Y, Chi, X.M, Zhou, Q. | Deposit date: | 2021-01-18 | Release date: | 2021-03-31 | Last modified: | 2021-06-16 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural basis for the different states of the spike protein of SARS-CoV-2 in complex with ACE2. Cell Res., 31, 2021
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7DX9
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![BU of 7dx9 by Molmil](/molmil-images/mine/7dx9) | Trypsin-digested S protein of SARS-CoV-2 bound with PD of ACE2 in the conformation 3 (3 up RBD and 2 PD bound) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | Authors: | Yan, R.H, Zhang, Y.Y, Li, Y.N, Ye, F.F, Guo, Y.Y, Xia, L, Zhong, X.Y, Chi, X.M, Zhou, Q. | Deposit date: | 2021-01-18 | Release date: | 2021-03-31 | Last modified: | 2021-06-16 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural basis for the different states of the spike protein of SARS-CoV-2 in complex with ACE2. Cell Res., 31, 2021
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7DX7
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![BU of 7dx7 by Molmil](/molmil-images/mine/7dx7) | Trypsin-digested S protein of SARS-CoV-2 bound with PD of ACE2 in the conformation 1 (1 up RBD and 1 PD bound) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | Authors: | Yan, R.H, Zhang, Y.Y, Li, Y.N, Ye, F.F, Guo, Y.Y, Xia, L, Zhong, X.Y, Chi, X.M, Zhou, Q. | Deposit date: | 2021-01-18 | Release date: | 2021-03-31 | Last modified: | 2021-06-16 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural basis for the different states of the spike protein of SARS-CoV-2 in complex with ACE2. Cell Res., 31, 2021
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1LPP
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![BU of 1lpp by Molmil](/molmil-images/mine/1lpp) | |
2B5Y
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![BU of 2b5y by Molmil](/molmil-images/mine/2b5y) | |
1LPO
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![BU of 1lpo by Molmil](/molmil-images/mine/1lpo) | |
6L15
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![BU of 6l15 by Molmil](/molmil-images/mine/6l15) | Crystal structure of Ser/Thr kinase Pim1 in complex with 10-DEBC derivatives | Descriptor: | 7-chloranyl-5-[3-[(3~{S})-piperidin-3-yl]propyl]pyrido[3,4-b][1,4]benzoxazine, Serine/threonine-protein kinase pim-1 | Authors: | Zhang, W, Xie, Y, Cao, R, Huang, N, Zhou, Y. | Deposit date: | 2019-09-27 | Release date: | 2020-05-27 | Last modified: | 2020-07-08 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure-Based Optimization of 10-DEBC Derivatives as Potent and Selective Pim-1 Kinase Inhibitors. J.Chem.Inf.Model., 60, 2020
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6L12
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![BU of 6l12 by Molmil](/molmil-images/mine/6l12) | Crystal structure of Ser/Thr kinase Pim1 in complex with 10-DEBC derivatives | Descriptor: | 4-[(2-chloranylphenoxazin-10-yl)methyl]cyclohexan-1-amine, Serine/threonine-protein kinase pim-1 | Authors: | Zhang, W, Xie, Y, Cao, R, Huang, N, Zhou, Y. | Deposit date: | 2019-09-27 | Release date: | 2020-05-27 | Last modified: | 2020-07-08 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Structure-Based Optimization of 10-DEBC Derivatives as Potent and Selective Pim-1 Kinase Inhibitors. J.Chem.Inf.Model., 60, 2020
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1LPM
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![BU of 1lpm by Molmil](/molmil-images/mine/1lpm) | A STRUCTURAL BASIS FOR THE CHIRAL PREFERENCES OF LIPASES | Descriptor: | (1R)-MENTHYL HEXYL PHOSPHONATE GROUP, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Grochulski, P.G, Cygler, M.C. | Deposit date: | 1995-01-06 | Release date: | 1995-04-20 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | A Structural Basis for the Chiral Preferences of Lipases J.Am.Chem.Soc., 116, 1994
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1LPN
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![BU of 1lpn by Molmil](/molmil-images/mine/1lpn) | |
1HSH
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![BU of 1hsh by Molmil](/molmil-images/mine/1hsh) | |
6L16
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![BU of 6l16 by Molmil](/molmil-images/mine/6l16) | Crystal structure of Ser/Thr kinase Pim1 in complex with 10-DEBC derivatives | Descriptor: | 2-[4-[2-(7-chloranylpyrido[3,4-b][1,4]benzoxazin-5-yl)ethyl]piperidin-1-yl]ethanamine, Serine/threonine-protein kinase pim-1 | Authors: | Zhang, W, Xie, Y, Cao, R, Huang, N, Zhou, Y. | Deposit date: | 2019-09-27 | Release date: | 2020-05-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure-Based Optimization of 10-DEBC Derivatives as Potent and Selective Pim-1 Kinase Inhibitors. J.Chem.Inf.Model., 60, 2020
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6L17
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![BU of 6l17 by Molmil](/molmil-images/mine/6l17) | Crystal structure of Ser/Thr kinase Pim1 in complex with 10-DEBC derivatives | Descriptor: | 7-chloranyl-5-[3-[(3~{S})-piperidin-3-yl]propyl]pyrido[3,4-b][1,4]benzoxazin-8-amine, Serine/threonine-protein kinase pim-1 | Authors: | Zhang, W, Xie, Y, Cao, R, Huang, N, Zhou, Y. | Deposit date: | 2019-09-27 | Release date: | 2020-09-02 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structure-Based Optimization of 10-DEBC Derivatives as Potent and Selective Pim-1 Kinase Inhibitors. J.Chem.Inf.Model., 60, 2020
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6L11
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![BU of 6l11 by Molmil](/molmil-images/mine/6l11) | Crystal structure of Ser/Thr kinase Pim1 in complex with 10-DEBC derivatives | Descriptor: | 5-(2-chloranylphenoxazin-10-yl)-~{N},~{N}-diethyl-pentan-1-amine, Serine/threonine-protein kinase pim-1 | Authors: | Zhang, W, Xie, Y, Cao, R, Huang, N, Zhou, Y. | Deposit date: | 2019-09-27 | Release date: | 2020-05-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structure-Based Optimization of 10-DEBC Derivatives as Potent and Selective Pim-1 Kinase Inhibitors. J.Chem.Inf.Model., 60, 2020
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4L02
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![BU of 4l02 by Molmil](/molmil-images/mine/4l02) | Crystal Structure of SphK1 with inhibitor | Descriptor: | (2R,4S)-1-[2-(4-{[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]amino}phenyl)ethyl]-2-(hydroxymethyl)piperidin-4-ol, Sphingosine kinase 1 | Authors: | Min, X, Walker, N, Wang, Z. | Deposit date: | 2013-05-30 | Release date: | 2013-07-24 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structure guided design of a series of sphingosine kinase (SphK) inhibitors. Bioorg.Med.Chem.Lett., 23, 2013
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1MFA
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![BU of 1mfa by Molmil](/molmil-images/mine/1mfa) | |
2F3I
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![BU of 2f3i by Molmil](/molmil-images/mine/2f3i) | Solution Structure of a Subunit of RNA Polymerase II | Descriptor: | DNA-directed RNA polymerases I, II, and III 17.1 kDa polypeptide | Authors: | Kang, X, Jin, C. | Deposit date: | 2005-11-21 | Release date: | 2006-05-02 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structural, biochemical, and dynamic characterizations of the hRPB8 subunit of human RNA polymerases J.Biol.Chem., 281, 2006
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8XT2
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![BU of 8xt2 by Molmil](/molmil-images/mine/8xt2) | Cryo-EM structure of the human 55S mitoribosome with 10uM Tigecycline | Descriptor: | 12s rRNA, 16s rRNA, 39S ribosomal protein L22, ... | Authors: | Li, X, Wang, M, Cheng, J. | Deposit date: | 2024-01-10 | Release date: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
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8XQN
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![BU of 8xqn by Molmil](/molmil-images/mine/8xqn) | Structure of human class T GPCR TAS2R14-DNGi complex with Aristolochic acid A. | Descriptor: | 8-methoxy-6-nitro-naphtho[1,2-e][1,3]benzodioxole-5-carboxylic acid, CHOLESTEROL, Exo-alpha-sialidase,Taste receptor type 2 member 14,LgBiT, ... | Authors: | Hu, X.L, Wu, L.J, Hua, T, Liu, Z.J. | Deposit date: | 2024-01-05 | Release date: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.05 Å) | Cite: | Bitter taste TAS2R14 activation by intracellular tastants and cholesterol. Nature, 2024
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8XQL
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![BU of 8xql by Molmil](/molmil-images/mine/8xql) | Structure of human class T GPCR TAS2R14-miniGs/gust complex with Aristolochic acid A. | Descriptor: | 8-methoxy-6-nitro-naphtho[1,2-e][1,3]benzodioxole-5-carboxylic acid, CHOLESTEROL, Exo-alpha-sialidase,Taste receptor type 2 member 14,LgBiT, ... | Authors: | Hu, X.L, Wu, L.J, Hua, T, Liu, Z.J. | Deposit date: | 2024-01-05 | Release date: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.99 Å) | Cite: | Bitter taste TAS2R14 activation by intracellular tastants and cholesterol. Nature, 2024
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8XT0
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![BU of 8xt0 by Molmil](/molmil-images/mine/8xt0) | Cryo-EM structure of the human 55S mitoribosome with 5um Tigecycline | Descriptor: | 12s rRNA, 16s rRNA, 39S ribosomal protein L22, ... | Authors: | Li, X, Wang, M, Cheng, J. | Deposit date: | 2024-01-10 | Release date: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
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8XQR
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![BU of 8xqr by Molmil](/molmil-images/mine/8xqr) | Structure 2 of human class T GPCR TAS2R14-miniGs/gust complex with Flufenamic acid. | Descriptor: | 2-[[3-(TRIFLUOROMETHYL)PHENYL]AMINO] BENZOIC ACID, Exo-alpha-sialidase,Taste receptor type 2 member 14,LgBiT, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Hu, X.L, Wu, L.J, Hua, T, Liu, Z.J. | Deposit date: | 2024-01-05 | Release date: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Bitter taste TAS2R14 activation by intracellular tastants and cholesterol. Nature, 2024
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8XQO
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![BU of 8xqo by Molmil](/molmil-images/mine/8xqo) | Structure of human class T GPCR TAS2R14-Gi complex with Aristolochic acid A. | Descriptor: | 8-methoxy-6-nitro-naphtho[1,2-e][1,3]benzodioxole-5-carboxylic acid, CHOLESTEROL, Exo-alpha-sialidase,Taste receptor type 2 member 14,LgBiT, ... | Authors: | Hu, X.L, Wu, L.J, Hua, T, Liu, Z.J. | Deposit date: | 2024-01-05 | Release date: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.77 Å) | Cite: | Bitter taste TAS2R14 activation by intracellular tastants and cholesterol. Nature, 2024
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8Y74
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![BU of 8y74 by Molmil](/molmil-images/mine/8y74) | |