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8TVS
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BU of 8tvs by Molmil
Cryo-EM structure of backtracked Pol II in complex with Rad26
Descriptor: DNA (NTS), DNA (TS), DNA repair and recombination protein RAD26, ...
Authors:Sarsam, R.D, Lahiri, I, Leschziner, A.E.
Deposit date:2023-08-18
Release date:2024-01-24
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair.
Proc.Natl.Acad.Sci.USA, 121, 2024
8TUG
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BU of 8tug by Molmil
Cryo-EM structure of CPD-stalled Pol II in complex with Rad26 (engaged state)
Descriptor: DNA (NTS), DNA (TS), DNA repair and recombination protein RAD26, ...
Authors:Sarsam, R.D, Lahiri, I, Leschziner, A.E.
Deposit date:2023-08-16
Release date:2024-01-24
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair.
Proc.Natl.Acad.Sci.USA, 121, 2024
8KEE
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BU of 8kee by Molmil
Cyanophage A-1(L) sheath-tube
Descriptor: sheath, tube
Authors:Yu, R.C, Li, Q, Zhou, C.Z.
Deposit date:2023-08-11
Release date:2024-04-10
Method:ELECTRON MICROSCOPY (3.26 Å)
Cite:Structure of the intact tail machine of Anabaena myophage A-1(L).
Nat Commun, 15, 2024
8KEA
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BU of 8kea by Molmil
Cyanophage A-1(L) baseplate-initiators
Descriptor: baseplate gp16, central spike, hub, ...
Authors:Yu, R.C, Li, Q, Zhou, C.Z.
Deposit date:2023-08-11
Release date:2024-04-10
Method:ELECTRON MICROSCOPY (3.44 Å)
Cite:Structure of the intact tail machine of Anabaena myophage A-1(L).
Nat Commun, 15, 2024
8KE9
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BU of 8ke9 by Molmil
The CBD domain of cyanophage A-1(L) short tail fiber
Descriptor: Tail fiber protein
Authors:Yu, R.C, Li, Q, Zhou, C.Z.
Deposit date:2023-08-11
Release date:2024-04-10
Method:ELECTRON MICROSCOPY (3.76 Å)
Cite:Structure of the intact tail machine of Anabaena myophage A-1(L).
Nat Commun, 15, 2024
8KEF
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BU of 8kef by Molmil
Cyanophage A-1(L) neck/gp7-terminator
Descriptor: Neck gp7, Terminator gp8
Authors:Yu, R.C, Li, Q, Zhou, C.Z.
Deposit date:2023-08-11
Release date:2024-04-17
Method:ELECTRON MICROSCOPY (3.44 Å)
Cite:Structure of the intact tail machine of Anabaena myophage A-1(L).
Nat Commun, 15, 2024
8KEG
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BU of 8keg by Molmil
Cyanophage A-1(L) neck/gp5-neck fiber
Descriptor: Neck gp5, neck fiber gp82N
Authors:Yu, R.C, Li, Q, Zhou, C.Z.
Deposit date:2023-08-11
Release date:2024-04-17
Method:ELECTRON MICROSCOPY (3.66 Å)
Cite:Structure of the intact tail machine of Anabaena myophage A-1(L).
Nat Commun, 15, 2024
8KEC
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BU of 8kec by Molmil
Cyanophage A-1(L) tail fiber
Descriptor: Long tail fiber, short tail fiber
Authors:Yu, R.C, Li, Q, Zhou, C.Z.
Deposit date:2023-08-11
Release date:2024-04-10
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structure of the intact tail machine of Anabaena myophage A-1(L).
Nat Commun, 15, 2024
8J00
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BU of 8j00 by Molmil
Human KCNQ2-CaM in complex with CBD
Descriptor: Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 2, cannabidiol
Authors:Ma, D, Li, X, Guo, J.
Deposit date:2023-04-09
Release date:2023-11-29
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Ligand activation mechanisms of human KCNQ2 channel.
Nat Commun, 14, 2023
8IZY
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BU of 8izy by Molmil
Human KCNQ2-CaM in complex with HN37
Descriptor: Potassium voltage-gated channel subfamily KQT member 2, methyl N-[4-[(4-fluorophenyl)methyl-prop-2-ynyl-amino]-2,6-dimethyl-phenyl]carbamate
Authors:Ma, D, Li, X, Guo, J.
Deposit date:2023-04-09
Release date:2023-11-29
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Ligand activation mechanisms of human KCNQ2 channel.
Nat Commun, 14, 2023
8J05
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BU of 8j05 by Molmil
Human KCNQ2-CaM complex in the presence of PIP2
Descriptor: Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 2
Authors:Ma, D, Li, X, Guo, J.
Deposit date:2023-04-09
Release date:2023-12-06
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Ligand activation mechanisms of human KCNQ2 channel.
Nat Commun, 14, 2023
8J03
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BU of 8j03 by Molmil
Human KCNQ2(F104A)-CaM-PIP2-CBD complex in state I
Descriptor: Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 2, cannabidiol
Authors:Ma, D, Li, D, Guo, J.
Deposit date:2023-04-09
Release date:2023-12-06
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Ligand activation mechanisms of human KCNQ2 channel.
Nat Commun, 14, 2023
8J04
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BU of 8j04 by Molmil
Human KCNQ2-CaM-HN37 complex in the presence of PIP2
Descriptor: Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 2, methyl N-[4-[(4-fluorophenyl)methyl-prop-2-ynyl-amino]-2,6-dimethyl-phenyl]carbamate
Authors:Ma, D, Li, X, Guo, J.
Deposit date:2023-04-09
Release date:2023-12-06
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Ligand activation mechanisms of human KCNQ2 channel.
Nat Commun, 14, 2023
8J02
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BU of 8j02 by Molmil
Human KCNQ2(F104A)-CaM-PIP2-CBD complex in state II
Descriptor: Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 2, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate, ...
Authors:Ma, D, Li, X, Guo, J.
Deposit date:2023-04-09
Release date:2023-12-13
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Ligand activation mechanisms of human KCNQ2 channel.
Nat Commun, 14, 2023
8J01
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BU of 8j01 by Molmil
Human KCNQ2-CaM in complex with CBD and PIP2
Descriptor: Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 2, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate, ...
Authors:Ma, D, Li, X, Guo, J.
Deposit date:2023-04-09
Release date:2023-12-13
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Ligand activation mechanisms of human KCNQ2 channel.
Nat Commun, 14, 2023
6KZ5
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BU of 6kz5 by Molmil
Crystal Structure Analysis of the Csn-B-bounded NUR77 Ligand binding Domain
Descriptor: Nuclear receptor subfamily 4 group A member 1, ethyl 2-[2-octanoyl-3,5-bis(oxidanyl)phenyl]ethanoate
Authors:Hong, W, Chen, H, Wu, Q, Lin, T.
Deposit date:2019-09-23
Release date:2020-10-14
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (4.45 Å)
Cite:Blocking PPAR gamma interaction facilitates Nur77 interdiction of fatty acid uptake and suppresses breast cancer progression.
Proc.Natl.Acad.Sci.USA, 117, 2020
7YPX
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BU of 7ypx by Molmil
Cyanophage Pam3 fiber
Descriptor: Pam3 tail fiber proreins, tail fiber chaperone
Authors:Wei, Z.L, Jiang, Y.L, Zhou, C.Z.
Deposit date:2022-08-04
Release date:2022-11-09
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:Structural Insights into the Chaperone-Assisted Assembly of a Simplified Tail Fiber of the Myocyanophage Pam3.
Viruses, 14, 2022
8J6T
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BU of 8j6t by Molmil
Cryo-EM structure of the double CAF-1 bound right-handed Di-tetrasome
Descriptor: Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B, Histone H3.1, ...
Authors:Liu, C.P, Yu, Z.Y, Xu, R.M.
Deposit date:2023-04-26
Release date:2023-08-16
Last modified:2023-09-06
Method:ELECTRON MICROSCOPY (6.6 Å)
Cite:Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1.
Science, 381, 2023
8J6S
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BU of 8j6s by Molmil
Cryo-EM structure of the single CAF-1 bound right-handed Di-tetrasome
Descriptor: Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B, Histone H3.1, ...
Authors:Liu, C.P, Yu, Z.Y, Xu, R.M.
Deposit date:2023-04-26
Release date:2023-08-16
Last modified:2023-09-06
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1.
Science, 381, 2023
5V0Q
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BU of 5v0q by Molmil
Original engineered variant of I-OnuI meganuclease targeting the HIV integrase gene; harbors 49 point mutations relative to wild-type I-OnuI
Descriptor: CALCIUM ION, DNA (26-MER), I-OnuI_e-vHIVInt_v1
Authors:Werther, R, Lambert, A.R.
Deposit date:2017-02-28
Release date:2017-09-27
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Tuning DNA binding affinity and cleavage specificity of an engineered gene-targeting nuclease via surface display, flow cytometry and cellular analyses.
Protein Eng. Des. Sel., 30, 2017
7CMD
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BU of 7cmd by Molmil
Crystal structure of the SARS-CoV-2 PLpro with GRL0617
Descriptor: 5-amino-2-methyl-N-[(1R)-1-naphthalen-1-ylethyl]benzamide, Non-structural protein 3, ZINC ION
Authors:Gao, X, Cui, S.
Deposit date:2020-07-27
Release date:2020-09-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Crystal structure of SARS-CoV-2 papain-like protease.
Acta Pharm Sin B, 11, 2021
7CJD
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BU of 7cjd by Molmil
Crystal structure of the SARS-CoV-2 PLpro C111S mutant
Descriptor: 1,2-ETHANEDIOL, Non-structural protein 3, ZINC ION
Authors:Gao, X, Cui, S.
Deposit date:2020-07-10
Release date:2020-09-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.501 Å)
Cite:Crystal structure of SARS-CoV-2 papain-like protease.
Acta Pharm Sin B, 11, 2021
7Y5K
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BU of 7y5k by Molmil
Crystal structure of human CAF-1 core complex in spacegroup C2221
Descriptor: Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B, GLYCEROL, ...
Authors:Liu, C.P, Wang, M.Z, Xu, R.M.
Deposit date:2022-06-17
Release date:2023-08-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.48 Å)
Cite:Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1.
Science, 381, 2023
7Y61
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BU of 7y61 by Molmil
Cryo-EM structure of the two CAF1LCs bound right-handed Di-tetrasome
Descriptor: Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B, Histone H3.1, ...
Authors:Liu, C.P, Yu, Z.Y, Yu, C, Xu, R.M.
Deposit date:2022-06-18
Release date:2023-08-16
Last modified:2023-09-06
Method:ELECTRON MICROSCOPY (5.6 Å)
Cite:Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1.
Science, 381, 2023
7Y5V
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BU of 7y5v by Molmil
Cryo-EM structure of the dimeric human CAF1LC-H3-H4 complex
Descriptor: Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B, Histone H3.1, ...
Authors:Liu, C.P, Yu, C, Yu, Z.Y, Xu, R.M.
Deposit date:2022-06-17
Release date:2023-08-16
Last modified:2023-09-06
Method:ELECTRON MICROSCOPY (6.1 Å)
Cite:Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1.
Science, 381, 2023

222926

數據於2024-07-24公開中

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