2NBW
| Solution structure of the Rpn1 T1 site with the Rad23 UBL domain | Descriptor: | 26S proteasome regulatory subunit RPN1, UV excision repair protein RAD23 | Authors: | Chen, X, Walters, K.J. | Deposit date: | 2016-03-14 | Release date: | 2016-07-20 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structures of Rpn1 T1:Rad23 and hRpn13:hPLIC2 Reveal Distinct Binding Mechanisms between Substrate Receptors and Shuttle Factors of the Proteasome. Structure, 24, 2016
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2NBV
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2NBU
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9DK4
| ancestral hydroxynitrile lyase with fifteen substitutions | Descriptor: | Fifteen-substitution variant of an ancestral hydroxynitrile lyase, SODIUM ION | Authors: | Sarak, S.C, Tan, P, Evans III, R.L, Shi, K, Kazlauskas, R.J, Aihara, H, Pierce, C.T, Walsh, M.E, Greenberg, L.R. | Deposit date: | 2024-09-07 | Release date: | 2024-10-02 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | To be published To Be Published
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6CA4
| Crystal structure of humanized D. rerio TDP2 by 14 mutations | Descriptor: | 1,2-ETHANEDIOL, MAGNESIUM ION, MALONATE ION, ... | Authors: | Shi, K, Aihrara, H. | Deposit date: | 2018-01-29 | Release date: | 2018-05-02 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.623 Å) | Cite: | New fluorescence-based high-throughput screening assay for small molecule inhibitors of tyrosyl-DNA phosphodiesterase 2 (TDP2). Eur J Pharm Sci, 118, 2018
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6WDZ
| Porcine circovirus 2 Rep domain complexed with a single-stranded DNA 10-mer comprising the cleavage site | Descriptor: | 1,2-ETHANEDIOL, ATP-dependent helicase Rep, DNA (5'-D(*TP*AP*GP*TP*AP*TP*TP*AP*CP*C)-3'), ... | Authors: | Litzau, L.A, Tompkins, K, Shi, K, Nelson, A, Evans III, R.L, Gordon, W.R. | Deposit date: | 2020-04-01 | Release date: | 2020-12-16 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Molecular underpinnings of ssDNA specificity by Rep HUH-endonucleases and implications for HUH-tag multiplexing and engineering. Nucleic Acids Res., 49, 2021
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6WE1
| Wheat dwarf virus Rep domain complexed with a single-stranded DNA 8-mer comprising the cleavage site | Descriptor: | DNA (5'-D(*AP*AP*TP*AP*TP*TP*AP*C)-3'), MANGANESE (II) ION, Replication-associated protein | Authors: | Tompkins, K, Litzau, L.A, Pornschloegl, L, Nelson, A.T, Evans III, R.L, Gordon, W.R. | Deposit date: | 2020-04-01 | Release date: | 2020-12-16 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.612 Å) | Cite: | Molecular underpinnings of ssDNA specificity by Rep HUH-endonucleases and implications for HUH-tag multiplexing and engineering. Nucleic Acids Res., 49, 2021
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6WE0
| Wheat dwarf virus Rep domain complexed with a single-stranded DNA 10-mer comprising the cleavage site | Descriptor: | DNA (5'-D(*TP*AP*AP*TP*AP*TP*TP*AP*CP*C)-3'), MANGANESE (II) ION, Replication-associated protein | Authors: | Tompkins, K, Litzau, L.A, Shi, K, Nelson, A, Evans III, R.L, Gordon, W.R. | Deposit date: | 2020-04-01 | Release date: | 2020-12-16 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Molecular underpinnings of ssDNA specificity by Rep HUH-endonucleases and implications for HUH-tag multiplexing and engineering. Nucleic Acids Res., 49, 2021
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7KII
| Muscovy duck circovirus Rep domain complexed with a single-stranded DNA 10-mer comprising the cleavage site and Mn2+ | Descriptor: | ATP-dependent helicase Rep, CALCIUM ION, DNA (5'-D(*TP*AP*TP*TP*AP*TP*TP*AP*CP*C)-3'), ... | Authors: | Tompkins, K.J, Gordon, W.R, Shi, K. | Deposit date: | 2020-10-23 | Release date: | 2021-11-17 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Watson-Crick Base-Pairing Requirements for ssDNA Recognition and Processing in Replication-Initiating HUH Endonucleases. Mbio, 14, 2023
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7KIJ
| Muscovy duck circovirus Rep domain complexed with a single-stranded DNA 10-mer comprising the cleavage site | Descriptor: | ATP-dependent helicase Rep, DNA (5'-D(*TP*AP*TP*TP*AP*TP*TP*AP*CP*C)-3'), GLYCEROL, ... | Authors: | Tompkins, K.J, Gordon, W.R, Shi, K. | Deposit date: | 2020-10-23 | Release date: | 2021-11-17 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Watson-Crick Base-Pairing Requirements for ssDNA Recognition and Processing in Replication-Initiating HUH Endonucleases. Mbio, 14, 2023
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7KIK
| Wheat dwarf virus Rep domain circular permutation complexed with a single-stranded DNA 10-mer comprising the cleavage site and Mn2+ | Descriptor: | DNA (5'-D(*TP*AP*AP*TP*AP*TP*TP*AP*CP*C)-3'), MANGANESE (II) ION, Replication-associated protein | Authors: | Tompkins, K.J, Gordon, W.R, Shi, K, Litzau, L.A. | Deposit date: | 2020-10-23 | Release date: | 2021-11-17 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Watson-Crick Base-Pairing Requirements for ssDNA Recognition and Processing in Replication-Initiating HUH Endonucleases. Mbio, 14, 2023
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8SNI
| Hydroxynitrile Lyase from Hevea brasiliensis with Forty Mutations | Descriptor: | (S)-hydroxynitrile lyase, 1,2-ETHANEDIOL, BENZOIC ACID, ... | Authors: | Walsh, M.E, Greenberg, L.R, Kazlauskas, R.J, Pierce, C.T, Aihara, H, Evans, R.L, Shi, K. | Deposit date: | 2023-04-27 | Release date: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | To be published To Be Published
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