6WE0
Wheat dwarf virus Rep domain complexed with a single-stranded DNA 10-mer comprising the cleavage site
Summary for 6WE0
Entry DOI | 10.2210/pdb6we0/pdb |
Descriptor | Replication-associated protein, DNA (5'-D(*TP*AP*AP*TP*AP*TP*TP*AP*CP*C)-3'), MANGANESE (II) ION, ... (4 entities in total) |
Functional Keywords | huh-tag, huh motif, replicase, viral protein, single stranded dna, ssdna, ssdna binding, replication, dna binding protein, replication-dna complex, replication/dna |
Biological source | Wheat dwarf virus More |
Total number of polymer chains | 2 |
Total formula weight | 18817.30 |
Authors | Tompkins, K.,Litzau, L.A.,Shi, K.,Nelson, A.,Evans III, R.L.,Gordon, W.R. (deposition date: 2020-04-01, release date: 2020-12-16, Last modification date: 2023-10-18) |
Primary citation | Tompkins, K.J.,Houtti, M.,Litzau, L.A.,Aird, E.J.,Everett, B.A.,Nelson, A.T.,Pornschloegl, L.,Limon-Swanson, L.K.,Evans, R.L.,Evans, K.,Shi, K.,Aihara, H.,Gordon, W.R. Molecular underpinnings of ssDNA specificity by Rep HUH-endonucleases and implications for HUH-tag multiplexing and engineering. Nucleic Acids Res., 49:1046-1064, 2021 Cited by PubMed: 33410911DOI: 10.1093/nar/gkaa1248 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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