6V5B
 
 | | Human Drosha and DGCR8 in complex with Primary MicroRNA (MP/RNA complex) - Active state | | Descriptor: | CALCIUM ION, Microprocessor complex subunit DGCR8, Pri-miR-16-2 (78-MER), ... | | Authors: | Partin, A, Zhang, K, Jeong, B, Herrell, E, Li, S, Chiu, W, Nam, Y. | | Deposit date: | 2019-12-04 | | Release date: | 2020-04-08 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Cryo-EM Structures of Human Drosha and DGCR8 in Complex with Primary MicroRNA.
Mol.Cell, 78, 2020
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2I2W
 | | Crystal Structure of Escherichia Coli Phosphoheptose Isomerase | | Descriptor: | GLYCEROL, Phosphoheptose isomerase | | Authors: | DeLeon, G, Blakely, K, Zhang, K, Wright, G, Junop, M. | | Deposit date: | 2006-08-17 | | Release date: | 2007-08-21 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structure and Function of Sedoheptulose-7-phosphate Isomerase, a Critical Enzyme for Lipopolysaccharide Biosynthesis and a Target for Antibiotic Adjuvants
J.Biol.Chem., 283, 2008
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2I22
 | | Crystal structure of Escherichia coli phosphoheptose isomerase in complex with reaction substrate sedoheptulose 7-phosphate | | Descriptor: | D-ALTRO-HEPT-2-ULOSE 7-PHOSPHATE, Phosphoheptose isomerase | | Authors: | Blakely, K, Zhang, K, DeLeon, G, Wright, G, Junop, M. | | Deposit date: | 2006-08-15 | | Release date: | 2007-08-21 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structure and Function of Sedoheptulose-7-phosphate Isomerase, a Critical Enzyme for Lipopolysaccharide Biosynthesis and a Target for Antibiotic Adjuvants
J.Biol.Chem., 283, 2008
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3QQ2
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3TK9
 | | Crystal structure of human granzyme H | | Descriptor: | Granzyme H, SULFATE ION | | Authors: | Wang, L, Zhang, K, Wu, L, Tong, L, Sun, F, Fan, Z. | | Deposit date: | 2011-08-25 | | Release date: | 2011-12-28 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural insights into the substrate specificity of human granzyme H: the functional roles of a novel RKR motif
J.Immunol., 188, 2012
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3TJV
 | | Crystal structure of human granzyme H with a peptidyl substrate | | Descriptor: | Granzyme H, PTSYAGDDSG, SULFATE ION | | Authors: | Wang, L, Zhang, K, Wu, L, Tong, L, Sun, F, Fan, Z. | | Deposit date: | 2011-08-25 | | Release date: | 2011-12-28 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural insights into the substrate specificity of human granzyme H: the functional roles of a novel RKR motif
J.Immunol., 188, 2012
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7LJY
 | | Cryo-EM structure of the B dENE construct complexed with a 28-mer poly(A) | | Descriptor: | B dENE construct, poly(A) | | Authors: | Torabi, S, Chen, Y, Zhang, K, Wang, J, DeGregorio, S, Vaidya, A, Su, Z, Pabit, S, Chiu, W, Pollack, L, Steitz, J. | | Deposit date: | 2021-02-01 | | Release date: | 2021-04-14 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (5.6 Å) | | Cite: | Structural analyses of an RNA stability element interacting with poly(A).
Proc.Natl.Acad.Sci.USA, 118, 2021
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7M7H
 | | 6-Deoxyerythronolide B synthase (DEBS) module 1 in complex with antibody fragment 1B2: State 1' | | Descriptor: | 1B2 (heavy chain), 1B2 (light chain), EryAI,6-deoxyerythronolide-B synthase EryA3, ... | | Authors: | Cogan, D.P, Zhang, K, Chiu, W, Khosla, C. | | Deposit date: | 2021-03-28 | | Release date: | 2021-11-17 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Mapping the catalytic conformations of an assembly-line polyketide synthase module.
Science, 374, 2021
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7M7F
 | | 6-Deoxyerythronolide B synthase (DEBS) module 1 in complex with antibody fragment 1B2: State 1 | | Descriptor: | 1B2 (heavy chain), 1B2 (light chain), EryAI,6-deoxyerythronolide-B synthase EryA3, ... | | Authors: | Cogan, D.P, Zhang, K, Chiu, W, Khosla, C. | | Deposit date: | 2021-03-28 | | Release date: | 2021-11-17 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Mapping the catalytic conformations of an assembly-line polyketide synthase module.
Science, 374, 2021
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7M7E
 | | 6-Deoxyerythronolide B synthase (DEBS) hybrid module (M3/1) in complex with antibody fragment 1B2 | | Descriptor: | 1B2 (heavy chain), 1B2 (light chain), 6-deoxyerythronolide-B synthase EryA2, ... | | Authors: | Cogan, D.P, Zhang, K, Chiu, W, Khosla, C. | | Deposit date: | 2021-03-28 | | Release date: | 2021-11-17 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Mapping the catalytic conformations of an assembly-line polyketide synthase module.
Science, 374, 2021
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7M7I
 | | 6-Deoxyerythronolide B synthase (DEBS) module 1 in complex with antibody fragment 1B2 (TE-free) | | Descriptor: | 1B2 (heavy chain), 1B2 (light chain), EryAI, ... | | Authors: | Cogan, D.P, Zhang, K, Chiu, W, Khosla, C. | | Deposit date: | 2021-03-28 | | Release date: | 2021-11-17 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Mapping the catalytic conformations of an assembly-line polyketide synthase module.
Science, 374, 2021
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7M7J
 | | 6-Deoxyerythronolide B synthase (DEBS) module 1 in complex with antibody fragment 1B2: "turnstile closed" state (TE-free) | | Descriptor: | 1B2 (heavy chain), 1B2 (light chain), EryAI | | Authors: | Cogan, D.P, Zhang, K, Chiu, W, Khosla, C. | | Deposit date: | 2021-03-28 | | Release date: | 2021-11-17 | | Method: | ELECTRON MICROSCOPY (4.3 Å) | | Cite: | Mapping the catalytic conformations of an assembly-line polyketide synthase module.
Science, 374, 2021
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7M7G
 | | 6-Deoxyerythronolide B synthase (DEBS) module 1 in complex with antibody fragment 1B2: State 2 | | Descriptor: | 1B2 (heavy chain), 1B2 (light chain), EryAI,6-deoxyerythronolide-B synthase EryA3, ... | | Authors: | Cogan, D.P, Zhang, K, Chiu, W, Khosla, C. | | Deposit date: | 2021-03-28 | | Release date: | 2021-11-17 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Mapping the catalytic conformations of an assembly-line polyketide synthase module.
Science, 374, 2021
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7N32
 | | protofilaments of microtubule doublets bound to outer-arm dynein | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Rao, Q, Zhang, K. | | Deposit date: | 2021-05-31 | | Release date: | 2021-09-29 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (4.5 Å) | | Cite: | Structures of outer-arm dynein array on microtubule doublet reveal a motor coordination mechanism.
Nat.Struct.Mol.Biol., 28, 2021
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3K6J
 | | Crystal structure of the dehydrogenase part of multifuctional enzyme 1 from C.elegans | | Descriptor: | PHOSPHATE ION, Protein F01G10.3, confirmed by transcript evidence, ... | | Authors: | Ouyang, Z, Zhang, K, Zhai, Y, Lu, J, Sun, F. | | Deposit date: | 2009-10-09 | | Release date: | 2010-10-13 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure of the dehydrogenase part of multifuctional enzyme 1 from C.elegans
To be Published
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4NSW
 | | Crystal structure of the BAR-PH domain of ACAP1 | | Descriptor: | Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 | | Authors: | Pang, X, Zhang, K, Ma, J, Zhou, Q, Sun, F. | | Deposit date: | 2013-11-29 | | Release date: | 2014-10-15 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | A PH Domain in ACAP1 Possesses Key Features of the BAR Domain in Promoting Membrane Curvature
Dev.Cell, 31, 2014
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7MWG
 | | 16-nm repeat microtubule doublet | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Rao, Q, Zhang, K. | | Deposit date: | 2021-05-17 | | Release date: | 2021-09-29 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Structures of outer-arm dynein array on microtubule doublet reveal a motor coordination mechanism.
Nat.Struct.Mol.Biol., 28, 2021
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3J17
 | | Structure of a transcribing cypovirus by cryo-electron microscopy | | Descriptor: | Structural protein VP3, Structural protein VP5, VP1 | | Authors: | Yang, C, Ji, G, Liu, H, Zhang, K, Liu, G, Sun, F, Zhu, P, Cheng, L. | | Deposit date: | 2011-12-25 | | Release date: | 2012-04-04 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Cryo-EM structure of a transcribing cypovirus.
Proc.Natl.Acad.Sci.USA, 109, 2012
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3JUE
 | | Crystal Structure of ArfGAP and ANK repeat domain of ACAP1 | | Descriptor: | ARFGAP with coiled-coil, ANK repeat and PH domain-containing protein 1, SULFATE ION, ... | | Authors: | Pang, X, Zhang, K, Ma, J, Zhou, Q, Sun, F. | | Deposit date: | 2009-09-15 | | Release date: | 2010-09-22 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Mechanistic insights into regulated cargo binding by ACAP1 protein
J.Biol.Chem., 287, 2012
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5AFR
 | | N-terminal fragment of dynein heavy chain | | Descriptor: | DYNEIN HEAVY CHAIN, CYTOPLASMIC | | Authors: | Urnavicius, L, Zhang, K, Diamant, A.G, Motz, C, Schlager, M.A, Yu, M, Patel, N.A, Robinson, C.V, Carter, A.P. | | Deposit date: | 2015-01-23 | | Release date: | 2015-02-18 | | Last modified: | 2018-04-25 | | Method: | X-RAY DIFFRACTION (5 Å) | | Cite: | The Structure of the Dynactin Complex and its Interaction with Dynein.
Science, 347, 2015
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5AFU
 | | Cryo-EM structure of dynein tail-dynactin-BICD2N complex | | Descriptor: | ACTIN, CYTOPLASMIC 1, ADENOSINE-5'-DIPHOSPHATE, ... | | Authors: | Urnavicius, L, Zhang, K, Diamant, A.G, Motz, C, Schlager, M.A, Yu, M, Patel, N.A, Robinson, C.V, Carter, A.P. | | Deposit date: | 2015-01-26 | | Release date: | 2015-03-11 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (8.2 Å) | | Cite: | The Structure of the Dynactin Complex and its Interaction with Dynein.
Science, 347, 2015
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1T4I
 | | Crystal Structure of a DNA Decamer Containing a Thymine-dimer | | Descriptor: | 5'-D(*CP*GP*AP*AP*TP*TP*AP*AP*GP*C)-3', 5'-D(*GP*CP*TP*TP*AP*AP*TP*TP*CP*G)-3' | | Authors: | Park, H, Zhang, K, Ren, Y, Nadji, S, Sinha, N, Taylor, J.S, Kang, C. | | Deposit date: | 2004-04-29 | | Release date: | 2004-05-25 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal Structure of a DNA Decamer Containing a cis-syn Thymine-dimer
Proc.Natl.Acad.Sci.USA, 99, 2002
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5EWP
 | | ARO (armadillo repeats only protein) from Plasmodium falciparum | | Descriptor: | ARO (armadillo repeats only protein) | | Authors: | Brown, C, Zhang, K, Emery, J, Prusty, D, Wetzel, J, Heincke, D, Gilberger, T, Junop, M. | | Deposit date: | 2015-11-20 | | Release date: | 2016-01-27 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | ARO (armadillo repeats only protein) from Plasmodium falciparum
To Be Published
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1SM5
 | | Crystal Structure of a DNA Decamer Containing a Thymine-dimer | | Descriptor: | 5'-D(*CP*GP*AP*AP*TP*TP*AP*AP*GP*C)-3', 5'-D(*GP*CP*(BRU)P*TP*AP*AP*TP*(BRU)P*CP*G)-3' | | Authors: | Park, H, Zhang, K, Ren, Y, Nadji, S, Sinha, N, Taylor, J.-S, Kang, C. | | Deposit date: | 2004-03-08 | | Release date: | 2004-05-25 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal Structure of a DNA Decamer Containing a Thymine-dimer
Proc.Natl.Acad.Sci.USA, 99, 2002
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6BCN
 | | I-LtrI E184D bound to cognate substrate (pre-cleavage complex) | | Descriptor: | CALCIUM ION, DNA (26-MER), Ribosomal protein 3/homing endonuclease-like fusion protein | | Authors: | Brown, C, Zhang, K, McMurrough, T.A, Gloor, G.B, Edgell, D.R, Junop, M. | | Deposit date: | 2017-10-20 | | Release date: | 2018-10-24 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Active site residue identity regulates cleavage preference of LAGLIDADG homing endonucleases.
Nucleic Acids Res., 46, 2018
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