7X4M
| Cryo-EM structure of Coxsackievirus B1 mature virion in complex with nAb 8A10 (classified from CVB1 mature virion in complex with 8A10, 2E6 and 9A3) | Descriptor: | 8A10 heavy chain, 8A10 light chain, Capsid protein VP4, ... | Authors: | Zheng, Q, Zhu, R, Sun, H, Cheng, T, Li, S, Xia, N. | Deposit date: | 2022-03-02 | Release date: | 2022-09-28 | Method: | ELECTRON MICROSCOPY (3.34 Å) | Cite: | Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail. Cell Host Microbe, 30, 2022
|
|
8GTD
| Cryo-EM model of the marine siphophage vB_DshS-R4C portal-adaptor complex | Descriptor: | Head-to-tail joining protein, Portal protein | Authors: | Huang, Y, Sun, H, Wei, S, Zheng, Q, Li, S, Zhang, R, Xia, N. | Deposit date: | 2022-09-08 | Release date: | 2023-07-12 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (4.7 Å) | Cite: | Structure and proposed DNA delivery mechanism of a marine roseophage. Nat Commun, 14, 2023
|
|
8GTB
| Cryo-EM structure of the marine siphophage vB_DshS-R4C tail tube protein | Descriptor: | Major tail protein | Authors: | Huang, Y, Sun, H, Wei, S, Zheng, Q, Li, S, Zhang, R, Xia, N. | Deposit date: | 2022-09-08 | Release date: | 2023-07-12 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.43 Å) | Cite: | Structure and proposed DNA delivery mechanism of a marine roseophage. Nat Commun, 14, 2023
|
|
8GTC
| Cryo-EM model of the marine siphophage vB_DshS-R4C baseplate-tail complex | Descriptor: | Distal tail protein, Hub protein, Major tail protein, ... | Authors: | Huang, Y, Sun, H, Wei, S, Zheng, Q, Li, S, Zhang, R, Xia, N. | Deposit date: | 2022-09-08 | Release date: | 2023-07-12 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Structure and proposed DNA delivery mechanism of a marine roseophage. Nat Commun, 14, 2023
|
|
8GTF
| Cryo-EM model of the marine siphophage vB_DshS-R4C stopper-terminator complex | Descriptor: | Head-to-tail joining protein, Major tail protein, Terminator protein | Authors: | Huang, Y, Sun, H, Wei, S, Zheng, Q, Li, S, Zhang, R, Xia, N. | Deposit date: | 2022-09-08 | Release date: | 2023-07-12 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (6.6 Å) | Cite: | Structure and proposed DNA delivery mechanism of a marine roseophage. Nat Commun, 14, 2023
|
|
5Y2V
| Strcutrue of the full-length CcmR complexed with 2-OG from Synechocystis PCC6803 | Descriptor: | 2-OXOGLUTARIC ACID, PHOSPHATE ION, Rubisco operon transcriptional regulator | Authors: | Jiang, Y.L, Wang, X.P, Sun, H, Cheng, W, Han, S.J, Li, W.F, Chen, Y, Zhou, C.Z. | Deposit date: | 2017-07-27 | Release date: | 2017-12-27 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Coordinating carbon and nitrogen metabolic signaling through the cyanobacterial global repressor NdhR. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
5Y2W
| Structure of Synechocystis PCC6803 CcmR regulatory domain in complex with 2-PG | Descriptor: | 2-PHOSPHOGLYCOLIC ACID, Rubisco operon transcriptional regulator | Authors: | Jiang, Y.L, Wang, X.P, Sun, H, Cheng, W, Cao, D.D, Han, S.J, Li, W.F, Chen, Y, Zhou, C.Z. | Deposit date: | 2017-07-27 | Release date: | 2017-12-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Coordinating carbon and nitrogen metabolic signaling through the cyanobacterial global repressor NdhR. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
7WI0
| SARS-CoV-2 Omicron variant spike in complex with three human neutralizing antibodies | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, IG c1437_light_IGLV1-40_IGLJ1, IG c934_light_IGKV1-5_IGKJ1, ... | Authors: | Zheng, Q, Li, S, Sun, H, Zheng, Z, Wang, S. | Deposit date: | 2022-01-01 | Release date: | 2022-06-22 | Method: | ELECTRON MICROSCOPY (3.82 Å) | Cite: | Three SARS-CoV-2 antibodies provide broad and synergistic neutralization against variants of concern, including Omicron. Cell Rep, 39, 2022
|
|
7WHZ
| SARS-CoV-2 spike protein in complex with three human neutralizing antibodies | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, IG c1437_light_IGLV1-40_IGLJ1, IG c934_light_IGKV1-5_IGKJ1, ... | Authors: | Zheng, Q, Li, S, Sun, H, Zheng, Z, Wang, S. | Deposit date: | 2022-01-01 | Release date: | 2022-06-22 | Method: | ELECTRON MICROSCOPY (3.42 Å) | Cite: | Three SARS-CoV-2 antibodies provide broad and synergistic neutralization against variants of concern, including Omicron. Cell Rep, 39, 2022
|
|
8I0C
| Crystal structure of Aldo-keto reductase 1C3 complexed with compound S0703 | Descriptor: | 1-[4-[3,5-bis(chloranyl)phenyl]-3-fluoranyl-phenyl]cyclopropane-1-carboxylic acid, Aldo-keto reductase family 1 member C3, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Jiang, J, He, S, Liu, Y, Fang, P, Sun, H. | Deposit date: | 2023-01-10 | Release date: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.33 Å) | Cite: | Development of Biaryl-Containing Aldo-Keto Reductase 1C3 (AKR1C3) Inhibitors for Reversing AKR1C3-Mediated Drug Resistance in Cancer Treatment. J.Med.Chem., 66, 2023
|
|
5Z49
| Crystal structure of the effector-binding domain of Synechococcus elongatus CmpR in complex with ribulose-1,5-bisphosphate | Descriptor: | HTH-type transcriptional activator CmpR, RIBULOSE-1,5-DIPHOSPHATE | Authors: | Jiang, Y.L, Mahounga, D.M, Sun, H. | Deposit date: | 2018-01-10 | Release date: | 2018-10-10 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.148 Å) | Cite: | Crystal structure of the effector-binding domain of Synechococcus elongatus CmpR in complex with ribulose 1,5-bisphosphate. Acta Crystallogr F Struct Biol Commun, 74, 2018
|
|
8W5A
| |
8W59
| |
7WP1
| Cryo-EM structure of SARS-CoV-2 Mu S6P trimer in complex with neutralizing antibody VacW-209 (local refinement) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, VacW-209 heavy chain, ... | Authors: | Zheng, Q, Sun, H, Ju, B, Zhang, Z, Li, S, Xia, N. | Deposit date: | 2022-01-22 | Release date: | 2022-07-13 | Last modified: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (3.77 Å) | Cite: | Immune escape by SARS-CoV-2 Omicron variant and structural basis of its effective neutralization by a broad neutralizing human antibody VacW-209. Cell Res., 32, 2022
|
|
7WP5
| Cryo-EM structure of SARS-CoV-2 Omicron S6P trimer in complex with neutralizing antibody VacW-209 (local refinement) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spikeprotein S1, VacW-209 heavy chain, ... | Authors: | Zheng, Q, Sun, H, Ju, B, Zhang, Z, Li, S, Xia, N. | Deposit date: | 2022-01-22 | Release date: | 2022-07-13 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Immune escape by SARS-CoV-2 Omicron variant and structural basis of its effective neutralization by a broad neutralizing human antibody VacW-209. Cell Res., 32, 2022
|
|
7WON
| Cryo-EM structure of SARS-CoV-2 S2P trimer in complex with neutralizing antibody VacW-209 (local refinement) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, VacW-209 heavy chain, ... | Authors: | Zheng, Q, Sun, H, Ju, B, Zhang, Z, Li, S, Xia, N. | Deposit date: | 2022-01-22 | Release date: | 2022-07-13 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Immune escape by SARS-CoV-2 Omicron variant and structural basis of its effective neutralization by a broad neutralizing human antibody VacW-209. Cell Res., 32, 2022
|
|
7WP0
| Cryo-EM structure of SARS-CoV-2 Delta S6P trimer in complex with neutralizing antibody VacW-209 (local refinement) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, IG c335_light_IGLV1-40_IGLJ3, Spike protein S1, ... | Authors: | Zheng, Q, Sun, H, Ju, B, Zhang, Z, Li, S, Xia, N. | Deposit date: | 2022-01-22 | Release date: | 2022-07-20 | Method: | ELECTRON MICROSCOPY (3.71 Å) | Cite: | Immune escape by SARS-CoV-2 Omicron variant and structural basis of its effective neutralization by a broad neutralizing human antibody VacW-209. Cell Res., 32, 2022
|
|
7WP2
| Cryo-EM structure of SARS-CoV-2 C.1.2 S6P trimer in complex with neutralizing antibody VacW-209 (local refinement) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, VacW-209 heavy chain, ... | Authors: | Zheng, Q, Sun, H, Ju, B, Zhang, Z, Li, S, Xia, N. | Deposit date: | 2022-01-22 | Release date: | 2022-07-20 | Method: | ELECTRON MICROSCOPY (3.52 Å) | Cite: | Immune escape by SARS-CoV-2 Omicron variant and structural basis of its effective neutralization by a broad neutralizing human antibody VacW-209. Cell Res., 32, 2022
|
|
3KZA
| Crystal structure of Gyuba, a patched chimera of b-lactglobulin | Descriptor: | Beta-lactoglobulin | Authors: | Tsuge, H, Ohtomo, H, Utsunomiya, H, Konuma, T, Ikeguchi, M. | Deposit date: | 2009-12-08 | Release date: | 2010-12-22 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure and stability of Gyuba, a patched chimera of b-lactoglobulin Protein Sci., 20, 2011
|
|
7CB0
| |
7CB5
| |
7CB6
| |
7CGC
| |
7CGD
| Silver-bound E.coli malate dehydrogenase | Descriptor: | Malate dehydrogenase, SILVER ION | Authors: | Wang, H, Wang, M, Sun, H. | Deposit date: | 2020-07-01 | Release date: | 2020-09-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Atomic differentiation of silver binding preference in protein targets: Escherichia coli malate dehydrogenase as a paradigm. Chem Sci, 11, 2020
|
|
7FFM
| Human serum transferrin with five osmium binding sites | Descriptor: | MALONATE ION, NITRILOTRIACETIC ACID, OSMIUM ION, ... | Authors: | Wang, M, Sun, H. | Deposit date: | 2021-07-23 | Release date: | 2022-06-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.06 Å) | Cite: | Binding of ruthenium and osmium at non‐iron sites of transferrin accounts for their iron-independent cellular uptake. J.Inorg.Biochem., 234, 2022
|
|