7X2I

Cryo-EM structure of Coxsackievirus B1 pre-A particle in complex with nAb 2E6 (CVB1-pre-A:2E6)

Summary for 7X2I

Entry DOI	10.2210/pdb7x2i/pdb
EMDB information	32968
Descriptor	2E6 light chain, 2E6 heavy chain, Virion protein 1, ... (6 entities in total)
Functional Keywords	coxsackievirus b1, neutralizing antiboy, cryo-em, virus
Biological source	Mus musculus More
Total number of polymer chains	6
Total formula weight	118954.46
Authors	Zheng, Q.,Zhu, R.,Sun, H.,Cheng, T.,Li, S.,Xia, N. (deposition date: 2022-02-25, release date: 2022-09-28, Last modification date: 2022-10-05)
Primary citation	Zheng, Q.,Zhu, R.,Yin, Z.,Xu, L.,Sun, H.,Yu, H.,Wu, Y.,Jiang, Y.,Huang, Q.,Huang, Y.,Zhang, D.,Liu, L.,Yang, H.,He, M.,Zhou, Z.,Jiang, Y.,Chen, Z.,Zhao, H.,Que, Y.,Kong, Z.,Zhou, L.,Li, T.,Zhang, J.,Luo, W.,Gu, Y.,Cheng, T.,Li, S.,Xia, N. Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail. Cell Host Microbe, 30:1279-, 2022 Cited by PubMed: 36002016 DOI: 10.1016/j.chom.2022.08.001 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.29 Å)

Structure validation