7BVK
| |
7BVJ
| |
7XLP
| MEK1 bound to DS03090629 | Descriptor: | (1~{R},3~{S})-3-[[6-[2-chloranyl-4-(4-methylpyrimidin-2-yl)oxy-phenyl]-3-methyl-1~{H}-indazol-4-yl]oxy]cyclohexan-1-amine, CALCIUM ION, DIMETHYL SULFOXIDE, ... | Authors: | Kishikawa, S, Takano, K, Ubukata, O, Hanzawa, H. | Deposit date: | 2022-04-22 | Release date: | 2023-03-01 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Discovery of a Novel ATP-Competitive MEK Inhibitor DS03090629 that Overcomes Resistance Conferred by BRAF Overexpression in BRAF-Mutated Melanoma. Mol.Cancer Ther., 22, 2023
|
|
7XNC
| MEK1 bound to DS94070624 | Descriptor: | CALCIUM ION, DIMETHYL SULFOXIDE, Dual specificity mitogen-activated protein kinase kinase 1, ... | Authors: | Kishikawa, S, Takano, K, Ubukata, O, Hanzawa, H. | Deposit date: | 2022-04-28 | Release date: | 2023-03-01 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Discovery of a Novel ATP-Competitive MEK Inhibitor DS03090629 that Overcomes Resistance Conferred by BRAF Overexpression in BRAF-Mutated Melanoma. Mol.Cancer Ther., 22, 2023
|
|
4XGK
| Crystal structure of UDP-galactopyranose mutase from Corynebacterium diphtheriae in complex with 2-[4-(4-chlorophenyl)-7-(2-thienyl)-2-thia-5,6,8,9-tetrazabicyclo[4.3.0]nona-4,7,9-trien-3-yl]acetic | Descriptor: | DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, SULFATE ION, UDP-galactopyranose mutase, ... | Authors: | Wangkanont, K, Heroux, A, Forest, K.T, Kiessling, L.L. | Deposit date: | 2014-12-31 | Release date: | 2015-08-12 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.652 Å) | Cite: | Virtual Screening for UDP-Galactopyranose Mutase Ligands Identifies a New Class of Antimycobacterial Agents. Acs Chem.Biol., 10, 2015
|
|
4WMQ
| |
4WMY
| |
6M6T
| Amylomaltase from Streptococcus agalactiae in complex with acarbose | Descriptor: | 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-1,5-anhydro-D-glucitol, 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... | Authors: | Wangkanont, K, Tumhom, S, Pongsawasdi, P. | Deposit date: | 2020-03-16 | Release date: | 2021-03-31 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Streptococcus agalactiae amylomaltase offers insight into the transglycosylation mechanism and the molecular basis of thermostability among amylomaltases. Sci Rep, 11, 2021
|
|
5ZC0
| |
2DFH
| Crystal structure of Tk-RNase HII(1-212)-C | Descriptor: | Ribonuclease HII | Authors: | Katagiri, Y, Takano, K, Chon, H, Matsumura, H, Koga, Y, Kanaya, S. | Deposit date: | 2006-03-01 | Release date: | 2007-03-06 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | Conformational contagion in a protein: Structural properties of a chameleon sequence Proteins, 68, 2007
|
|
2DF5
| Crystal Structure of Pf-PCP(1-204)-C | Descriptor: | Pyrrolidone-carboxylate peptidase | Authors: | Katagiri, Y, Takano, K, Chon, H, Matsumura, H, Koga, Y, Kanaya, S. | Deposit date: | 2006-02-24 | Release date: | 2007-03-06 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Conformational contagion in a protein: structural properties of a chameleon sequence Proteins, 68, 2007
|
|
2DFI
| Crystal structure of Pf-MAP(1-292)-C | Descriptor: | COBALT (II) ION, Methionine aminopeptidase | Authors: | Katagiri, Y, Takano, K, Chon, H, Matsumura, H, Koga, Y, Kanaya, S. | Deposit date: | 2006-03-01 | Release date: | 2007-03-06 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Conformational contagion in a protein: Structural properties of a chameleon sequence Proteins, 68, 2007
|
|
2DFE
| Crystal structure of Tk-RNase HII(1-200)-C | Descriptor: | Ribonuclease HII | Authors: | Katagiri, Y, Takano, K, Chon, H, Matsumura, H, Koga, Y, Kanaya, S. | Deposit date: | 2006-03-01 | Release date: | 2007-03-06 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Conformational contagion in a protein: Structural properties of a chameleon sequence Proteins, 68, 2007
|
|
2DFF
| Crystal structure of Tk-RNase HII(1-204)-C | Descriptor: | Ribonuclease HII | Authors: | Katagiri, Y, Takano, K, Chon, H, Matsumura, H, Koga, Y, Kanaya, S. | Deposit date: | 2006-03-01 | Release date: | 2007-03-06 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Conformational contagion in a protein: Structural properties of a chameleon sequence Proteins, 68, 2007
|
|
3A5E
| Crystal structure of 5K RNase Sa | Descriptor: | Guanyl-specific ribonuclease Sa | Authors: | Takano, K. | Deposit date: | 2009-08-06 | Release date: | 2010-08-04 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Urea denatured state ensembles contain extensive secondary structure that is increased in hydrophobic proteins Protein Sci., 19, 2010
|
|
3AA4
| A52V E.coli RNase HI | Descriptor: | Ribonuclease HI | Authors: | Takano, K. | Deposit date: | 2009-11-11 | Release date: | 2010-10-06 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Protein core adaptability: crystal structures of the cavity-filling variants of Escherichia coli RNase HI Protein Pept.Lett., 17, 2010
|
|
3ALY
| |
3AA3
| A52L E. coli RNase HI | Descriptor: | Ribonuclease HI | Authors: | Takano, K. | Deposit date: | 2009-11-11 | Release date: | 2010-10-06 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Protein core adaptability: crystal structures of the cavity-filling variants of Escherichia coli RNase HI Protein Pept.Lett., 17, 2010
|
|
3AA2
| A52I E. coli RNase HI | Descriptor: | Ribonuclease HI | Authors: | Takano, K. | Deposit date: | 2009-11-11 | Release date: | 2010-10-06 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Protein core adaptability: crystal structures of the cavity-filling variants of Escherichia coli RNase HI Protein Pept.Lett., 17, 2010
|
|
3AA5
| A52F E.coli RNase HI | Descriptor: | Ribonuclease HI | Authors: | Takano, K. | Deposit date: | 2009-11-11 | Release date: | 2010-10-06 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Protein core adaptability: crystal structures of the cavity-filling variants of Escherichia coli RNase HI Protein Pept.Lett., 17, 2010
|
|
5EGE
| Structure of ENPP6, a choline-specific glycerophosphodiester-phosphodiesterase | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Morita, J, Kano, K, Kato, K, Takita, H, Ishitani, R, Nishimasu, H, Nureki, O, Aoki, J. | Deposit date: | 2015-10-27 | Release date: | 2016-03-09 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure and biological function of ENPP6, a choline-specific glycerophosphodiester-phosphodiesterase Sci Rep, 6, 2016
|
|
5EGH
| Structure of ENPP6, a choline-specific glycerophosphodiester-phosphodiesterase in complex with phosphocholine | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Morita, J, Kano, K, Kato, K, Takita, H, Ishitani, R, Nishimasu, H, Nureki, O, Aoki, J. | Deposit date: | 2015-10-27 | Release date: | 2016-03-09 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.803 Å) | Cite: | Structure and biological function of ENPP6, a choline-specific glycerophosphodiester-phosphodiesterase Sci Rep, 6, 2016
|
|
3ABG
| X-ray Crystal Analysis of Bilirubin Oxidase from Myrothecium verrucaria at 2.3 angstrom Resolution using a Twin Crystal | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Bilirubin oxidase, COPPER (II) ION, ... | Authors: | Mizutani, K, Toyoda, M, Sagara, K, Takahashi, N, Sato, A, Kamitaka, Y, Tsujimura, S, Nakanishi, Y, Sugiura, T, Yamaguchi, S, Kano, K, Mikami, B. | Deposit date: | 2009-12-10 | Release date: | 2010-08-18 | Last modified: | 2023-07-26 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | X-ray analysis of bilirubin oxidase from Myrothecium verrucaria at 2.3 A resolution using a twinned crystal Acta Crystallogr.,Sect.F, 66, 2010
|
|
1PBY
| Structure of the Phenylhydrazine Adduct of the Quinohemoprotein Amine Dehydrogenase from Paracoccus denitrificans at 1.7 A Resolution | Descriptor: | HEME C, TERTIARY-BUTYL ALCOHOL, quinohemoprotein amine dehydrogenase 40 kDa subunit, ... | Authors: | Datta, S, Ikeda, T, Kano, K, Mathews, F.S. | Deposit date: | 2003-05-15 | Release date: | 2003-09-02 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure of the phenylhydrazine adduct of the quinohemoprotein amine dehydrogenase from Paracoccus denitrificans at 1.7 A resolution. Acta Crystallogr.,Sect.D, 59, 2003
|
|
8J83
| Crystal structure of formate dehydrogenase from Methylorubrum extorquens AM1 | Descriptor: | 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, DI(HYDROXYETHYL)ETHER, FE2/S2 (INORGANIC) CLUSTER, ... | Authors: | Kobayashi, A, Taketa, M, Sowa, K, Kano, K, Higuchi, Y, Ogata, H. | Deposit date: | 2023-04-29 | Release date: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure and function relationship of formate dehydrogenases: an overview of recent progress. Iucrj, 10, 2023
|
|