6L96
| Structure of PPARalpha-LBD/pemafibrate/SRC1 peptide | Descriptor: | (2~{R})-2-[3-[[1,3-benzoxazol-2-yl-[3-(4-methoxyphenoxy)propyl]amino]methyl]phenoxy]butanoic acid, Peroxisome proliferator-activated receptor alpha, SRC1 coactivator peptide | Authors: | Kawasaki, M, Kambe, A, Yamamoto, Y, Arulmozhira, S, Ito, S, Nakagawa, Y, Tokiwa, H, Nakano, S, Shimano, H. | Deposit date: | 2019-11-08 | Release date: | 2020-01-15 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Elucidation of Molecular Mechanism of a Selective PPAR alpha Modulator, Pemafibrate, through Combinational Approaches of X-ray Crystallography, Thermodynamic Analysis, and First-Principle Calculations. Int J Mol Sci, 21, 2020
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4GA6
| Crystal structure of AMP phosphorylase C-terminal deletion mutant in complex with substrates | Descriptor: | ADENOSINE MONOPHOSPHATE, Putative thymidine phosphorylase, SULFATE ION | Authors: | Nishitani, Y, Aono, R, Nakamura, A, Sato, T, Atomi, H, Imanaka, T, Miki, K. | Deposit date: | 2012-07-25 | Release date: | 2013-05-15 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Structure analysis of archaeal AMP phosphorylase reveals two unique modes of dimerization J.Mol.Biol., 425, 2013
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4GA4
| Crystal structure of AMP phosphorylase N-terminal deletion mutant | Descriptor: | PHOSPHATE ION, Putative thymidine phosphorylase | Authors: | Nishitani, Y, Aono, R, Nakamura, A, Sato, T, Atomi, H, Imanaka, T, Miki, K. | Deposit date: | 2012-07-25 | Release date: | 2013-05-15 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.51 Å) | Cite: | Structure analysis of archaeal AMP phosphorylase reveals two unique modes of dimerization J.Mol.Biol., 425, 2013
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6RWY
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4GA5
| Crystal structure of AMP phosphorylase C-terminal deletion mutant in the apo-form | Descriptor: | Putative thymidine phosphorylase | Authors: | Nishitani, Y, Aono, R, Nakamura, A, Sato, T, Atomi, H, Imanaka, T, Miki, K. | Deposit date: | 2012-07-25 | Release date: | 2013-05-15 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | Structure analysis of archaeal AMP phosphorylase reveals two unique modes of dimerization J.Mol.Biol., 425, 2013
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3HR0
| Crystal structure of Homo sapiens Conserved Oligomeric Golgi subunit 4 | Descriptor: | CoG4 | Authors: | Richardson, B.C, Ungar, D, Nakamura, A, Jeffrey, P.D, Hughson, F.M. | Deposit date: | 2009-06-08 | Release date: | 2009-07-21 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural basis for a human glycosylation disorder caused by mutation of the COG4 gene. Proc.Natl.Acad.Sci.USA, 106, 2009
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3IYZ
| Structure of Aquaporin-4 S180D mutant at 10.0 A resolution from electron micrograph | Descriptor: | Aquaporin-4 | Authors: | Mitsuma, T, Tani, K, Hiroaki, Y, Kamegawa, A, Suzuki, H, Hibino, H, Kurachi, Y, Fujiyoshi, Y. | Deposit date: | 2010-07-24 | Release date: | 2010-08-25 | Last modified: | 2023-09-06 | Method: | ELECTRON CRYSTALLOGRAPHY (10 Å) | Cite: | Influence of the cytoplasmic domains of aquaporin-4 on water conduction and array formation. J.Mol.Biol., 402, 2010
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1PAM
| CYCLODEXTRIN GLUCANOTRANSFERASE | Descriptor: | CALCIUM ION, CYCLODEXTRIN GLUCANOTRANSFERASE | Authors: | Harata, K, Haga, K, Nakamura, A, Aoyagi, M, Yamane, K. | Deposit date: | 1996-07-08 | Release date: | 1997-01-11 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | X-ray structure of cyclodextrin glucanotransferase from alkalophilic Bacillus sp. 1011. Comparison of two independent molecules at 1.8 A resolution. Acta Crystallogr.,Sect.D, 52, 1996
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2KTT
| Solution Structure of a Covalently Bound Pyrrolo[2,1-c][1,4]benzodiazepine-Benzimidazole Hybrid to a 10mer DNA Duplex | Descriptor: | (11aS)-7-methoxy-8-(3-{4-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]phenoxy}propoxy)-1,2,3,10,11,11a-hexahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-one, 5'-D(*AP*AP*CP*AP*AP*TP*TP*GP*TP*T)-3' | Authors: | Rettig, M, Weingarth, M, Langel, W, Kamal, A, Kumar, P.P, Weisz, K. | Deposit date: | 2010-02-08 | Release date: | 2010-03-09 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution structure of a covalently bound pyrrolo[2,1-c][1,4]benzodiazepine-benzimidazole hybrid to a 10mer DNA duplex. Biochemistry, 48, 2009
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2DB3
| Structural basis for RNA unwinding by the DEAD-box protein Drosophila Vasa | Descriptor: | 5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3', ATP-dependent RNA helicase vasa, MAGNESIUM ION, ... | Authors: | Sengoku, T, Nureki, O, Nakamura, A, Kobayashi, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-12-14 | Release date: | 2006-05-02 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis for RNA unwinding by the DEAD-box protein Drosophila Vasa. Cell(Cambridge,Mass.), 125, 2006
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2KY7
| NMR Structural Studies on the Covalent DNA Binding of a Pyrrolobenzodiazepine-Naphthalimide Conjugate | Descriptor: | 2-{2-[4-(3-{[(11aS)-7-methoxy-5-oxo-2,3,5,10,11,11a-hexahydro-1H-pyrrolo[2,1-c][1,4]benzodiazepin-8-yl]oxy}propyl)piperazin-1-yl]ethyl}-1H-benzo[de]isoquinoline-1,3(2H)-dione, 5'-D(*AP*AP*CP*AP*AP*TP*TP*GP*TP*T)-3' | Authors: | Rettig, M, Langel, W, Kamal, A, Weisz, K. | Deposit date: | 2010-05-17 | Release date: | 2010-06-02 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | NMR structural studies on the covalent DNA binding of a pyrrolobenzodiazepine-naphthalimide conjugate Org.Biomol.Chem., 8, 2010
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4PT6
| The discobody: an engineered discoidin domain from factor VIII that binds v 3 integrin with antibody-like affinities | Descriptor: | Coagulation factor VIII | Authors: | Kym, G, Shi, K, Kamajaya, A, Hamdouche, S, Kostecki, J.S, Wannier, T, Li, B, Nikolovski, P, Mayo, S.L. | Deposit date: | 2014-03-10 | Release date: | 2015-04-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The discobody: an engineered discoidin domain from factor VIII that binds v 3 integrin with antibody-like affinities To be Published
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2E0I
| Crystal structure of archaeal photolyase from Sulfolobus tokodaii with two FAD molecules: Implication of a novel light-harvesting cofactor | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 432aa long hypothetical deoxyribodipyrimidine photolyase, FLAVIN-ADENINE DINUCLEOTIDE | Authors: | Fujihashi, M, Numoto, N, Kobayashi, Y, Mizushima, A, Tsujimura, M, Nakamura, A, Kawarabayashi, Y, Miki, K. | Deposit date: | 2006-10-10 | Release date: | 2006-11-28 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal Structure of Archaeal Photolyase from Sulfolobus tokodaii with Two FAD Molecules: Implication of a Novel Light-harvesting Cofactor J.Mol.Biol., 365, 2007
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2D57
| Double layered 2D crystal structure of AQUAPORIN-4 (AQP4M23) at 3.2 a resolution by electron crystallography | Descriptor: | Aquaporin-4 | Authors: | Hiroaki, Y, Tani, K, Kamegawa, A, Gyobu, N, Nishikawa, K, Suzuki, H, Walz, T, Sasaki, S, Mitsuoka, K, Kimura, K, Mizoguchi, A, Fujiyoshi, Y. | Deposit date: | 2005-10-29 | Release date: | 2006-01-31 | Last modified: | 2023-11-08 | Method: | ELECTRON CRYSTALLOGRAPHY (3.2 Å) | Cite: | Implications of the Aquaporin-4 Structure on Array Formation and Cell Adhesion J.Mol.Biol., 355, 2005
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1YOO
| ASPARTATE AMINOTRANSFERASE MUTANT ATB17 WITH ISOVALERIC ACID | Descriptor: | ASPARTATE AMINOTRANSFERASE, ISOVALERIC ACID, PYRIDOXAL-5'-PHOSPHATE | Authors: | Oue, S, Okamoto, A, Yano, T, Kagamiyama, H. | Deposit date: | 1998-06-26 | Release date: | 1999-02-02 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Redesigning the substrate specificity of an enzyme by cumulative effects of the mutations of non-active site residues. J.Biol.Chem., 274, 1999
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2ATE
| Structure of the complex of PurE with NitroAIR | Descriptor: | ((2R,3S,4R,5R)-5-(5-AMINO-4-NITRO-1H-IMIDAZOL-1-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL)METHYL DIHYDROGEN PHOSPHATE, Phosphoribosylaminoimidazole carboxylase catalytic subunit | Authors: | Kappock, T.J, Mathews, I.I, Zaugg, J.B, Peng, P, Hoskins, A.A, Okamoto, A, Ealick, S.E, Stubbe, J. | Deposit date: | 2005-08-24 | Release date: | 2006-08-29 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | N5-CAIR mutase: role of a CO2 binding site and substrate movement in catalysis. Biochemistry, 46, 2007
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2AO5
| Crystal structure of an RNA duplex r(GGCGBrUGCGCU)2 with terminal and internal tandem G-U base pairs | Descriptor: | 5'-R(*GP*GP*CP*GP*(5BU)P*GP*CP*GP*CP*U)-3', MAGNESIUM ION | Authors: | Utsunomiya, R, Suto, K, Balasundaresan, D, Fukamizu, A, Kumar, P.K, Mizuno, H. | Deposit date: | 2005-08-12 | Release date: | 2006-03-28 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of an RNA duplex r(GGCGBrUGCGCU)2 with terminal and internal tandem G.U base pairs. Acta Crystallogr.,Sect.D, 62, 2006
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1PL7
| Human Sorbitol Dehydrogenase (apo) | Descriptor: | Sorbitol dehydrogenase, ZINC ION | Authors: | Pauly, T.A, Ekstrom, J.L, Beebe, D.A, Chrunyk, B, Cunningham, D, Griffor, M, Kamath, A, Lee, S.E, Madura, R, Mcguire, D, Subashi, T, Wasilko, D, Watts, P, Mylari, B.L, Oates, P.J, Adams, P.D, Rath, V.L. | Deposit date: | 2003-06-07 | Release date: | 2004-02-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | X-ray crystallographic and kinetic studies of human sorbitol dehydrogenase. Structure, 11, 2003
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1PL6
| Human SDH/NADH/inhibitor complex | Descriptor: | 4-[2-(HYDROXYMETHYL)PYRIMIDIN-4-YL]-N,N-DIMETHYLPIPERAZINE-1-SULFONAMIDE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Sorbitol dehydrogenase, ... | Authors: | Pauly, T.A, Ekstrom, J.L, Beebe, D.A, Chrunyk, B, Cunningham, D, Griffor, M, Kamath, A, Lee, S.E, Madura, R, Mcguire, D, Subashi, T, Wasilko, D, Watts, P, Mylari, B.L, Oates, P.J, Adams, P.D, Rath, V.L. | Deposit date: | 2003-06-07 | Release date: | 2004-02-17 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | X-ray crystallographic and kinetic studies of human sorbitol dehydrogenase. Structure, 11, 2003
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1PL8
| human SDH/NAD+ complex | Descriptor: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ZINC ION, human sorbitol dehydrogenase | Authors: | Pauly, T.A, Ekstrom, J.L, Beebe, D.A, Chrunyk, B, Cunningham, D, Griffor, M, Kamath, A, Lee, S.E, Madura, R, Mcguire, D, Subashi, T, Wasilko, D, Watts, P, Mylari, B.L, Oates, P.J, Adams, P.D, Rath, V.L. | Deposit date: | 2003-06-07 | Release date: | 2004-02-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | X-ray crystallographic and kinetic studies of human sorbitol dehydrogenase. Structure, 11, 2003
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1F53
| NMR STRUCTURE OF KILLER TOXIN-LIKE PROTEIN SKLP | Descriptor: | YEAST KILLER TOXIN-LIKE PROTEIN | Authors: | Ohki, S, Kariya, E, Hiraga, K, Wakamiya, A, Isobe, T, Oda, K, Kainosho, M. | Deposit date: | 2000-06-12 | Release date: | 2000-12-27 | Last modified: | 2022-02-16 | Method: | SOLUTION NMR | Cite: | NMR structure of Streptomyces killer toxin-like protein, SKLP: further evidence for the wide distribution of single-domain betagamma-crystallin superfamily proteins. J.Mol.Biol., 305, 2001
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3WKS
| Crystal structure of the SepCysS-SepCysE N-terminal domain complex from | Descriptor: | O-phospho-L-seryl-tRNA:Cys-tRNA synthase, Uncharacterized protein MJ1481 | Authors: | Nakazawa, Y, Asano, N, Nakamura, A, Yao, M. | Deposit date: | 2013-10-30 | Release date: | 2014-07-30 | Last modified: | 2022-08-24 | Method: | X-RAY DIFFRACTION (3.029 Å) | Cite: | Ancient translation factor is essential for tRNA-dependent cysteine biosynthesis in methanogenic archaea. Proc.Natl.Acad.Sci.USA, 111, 2014
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2Z0N
| Crystal structure of APPL1-BAR domain | Descriptor: | DCC-interacting protein 13-alpha | Authors: | Murayama, K, Kato-Murayama, M, Sakamoto, A, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-05-07 | Release date: | 2008-05-13 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal structure of APPL1-BAR domain To be Published
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2ZET
| Crystal structure of the small GTPase Rab27B complexed with the Slp homology domain of Slac2-a/melanophilin | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Melanophilin, ... | Authors: | Kukimoto-Niino, M, Sakamoto, A, Kanno, E, Hanawa-Suetsugu, K, Terada, T, Shirouzu, M, Fukuda, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-12-17 | Release date: | 2008-09-30 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural basis for the exclusive specificity of Slac2-a/melanophilin for the Rab27 GTPases. Structure, 16, 2008
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2ZWL
| Human factor viia-tissue factor complexed with highly selective peptide inhibitor | Descriptor: | 2-[[(2R)-1-[[(2S)-5-amino-1-[(4-carbamimidoylphenyl)methylamino]-1,5-dioxo-pentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxo-propan-2-yl]sulfamoyl]ethanoic acid, CALCIUM ION, Factor VII heavy chain, ... | Authors: | Kadono, S, Sakamoto, A, Kikuchi, Y, Oh-Eda, M, Yabuta, N, Koga, T, Hattori, K, Shiraishi, T, Haramura, M, Sato, H, Ohta, M, Kozono, T. | Deposit date: | 2008-12-16 | Release date: | 2009-01-20 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Human factor viia-tissue factor complexed with highly selective peptide inhibitor To be Published
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