3KBL
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![BU of 3kbl by Molmil](/molmil-images/mine/3kbl) | Crystal structure of the GLD-1 homodimerization domain from Caenorhabditis elegans N169A mutant at 2.28 A resolution | Descriptor: | Female germline-specific tumor suppressor gld-1 | Authors: | Beuck, C, Szymczyna, B.R, Kerkow, D.E, Carmel, A.B, Columbus, L, Stanfield, R.L, Williamson, J.R. | Deposit date: | 2009-10-20 | Release date: | 2010-03-09 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Structure of the GLD-1 homodimerization domain: insights into STAR protein-mediated translational regulation. Structure, 18, 2010
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5C7M
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![BU of 5c7m by Molmil](/molmil-images/mine/5c7m) | CRYSTAL STRUCTURE OF E3 LIGASE ITCH WITH A UB VARIANT | Descriptor: | E3 ubiquitin-protein ligase Itchy homolog, Polyubiquitin-C | Authors: | Walker, J.R, Hu, J, Dong, A, Wernimont, A, Zhang, W, Sidhu, S, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Tong, Y, Structural Genomics Consortium (SGC) | Deposit date: | 2015-06-24 | Release date: | 2016-03-16 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.03 Å) | Cite: | System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes. Mol.Cell, 62, 2016
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3KKA
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![BU of 3kka by Molmil](/molmil-images/mine/3kka) | Co-crystal structure of the sam domains of EPHA1 AND EPHA2 | Descriptor: | CHLORIDE ION, EPHRIN TYPE-A RECEPTOR 1, EPHRIN TYPE-A RECEPTOR 2 | Authors: | Walker, J.R, Yermekbayeva, L, Butler-Cole, C, Weigelt, J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2009-11-05 | Release date: | 2009-11-24 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Co-Crystal Structure of the SAM Domains of Human Ephrin Type-A Receptor 1 and Human Ephrin Type-A Receptor 2 To be Published
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3P1I
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![BU of 3p1i by Molmil](/molmil-images/mine/3p1i) | Ligand binding domain of human ephrin type-B receptor 3 | Descriptor: | CHLORIDE ION, Ephrin type-B receptor 3, SULFATE ION | Authors: | Walker, J.R, Yermekbayeva, L, Seitova, A, Kania, J, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2010-09-30 | Release date: | 2011-01-19 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Ligand Binding Domain of Human Ephb3 To be Published
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3JYU
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![BU of 3jyu by Molmil](/molmil-images/mine/3jyu) | Crystal structure of the N-terminal domains of the ubiquitin specific peptidase 4 (USP4) | Descriptor: | 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, Ubiquitin carboxyl-terminal hydrolase | Authors: | Bacik, J.P, Avvakumov, G, Walker, J.R, Xue, S, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2009-09-22 | Release date: | 2009-10-20 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.37 Å) | Cite: | Crystal structure of the N-terminal domains of the ubiquitin specific peptidase 4 (USP4) To be Published
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3K0W
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![BU of 3k0w by Molmil](/molmil-images/mine/3k0w) | Crystal structure of the tandem IG-like C2-type 2 domains of the human mucosa-associated lymphoid tissue lymphoma translocation protein 1 | Descriptor: | CHLORIDE ION, Mucosa-associated lymphoid tissue lymphoma translocation protein 1, isoform 2 | Authors: | Walker, J.R, Qiu, L, Butler-Cole, C, Weigelt, J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2009-09-25 | Release date: | 2009-10-27 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of the Tandem Ig-Like C2-Type 2 Domains of the Human Mucosa-Associated Lymphoid Tissue Lymphoma Translocation Protein 1. To be Published
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5C1M
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![BU of 5c1m by Molmil](/molmil-images/mine/5c1m) | Crystal structure of active mu-opioid receptor bound to the agonist BU72 | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2R,3S,3aR,5aR,6R,11bR,11cS)-3a-methoxy-3,14-dimethyl-2-phenyl-2,3,3a,6,7,11c-hexahydro-1H-6,11b-(epiminoethano)-3,5a-methanonaphtho[2,1-g]indol-10-ol, CHOLESTEROL, ... | Authors: | Huang, W.J, Manglik, A, Venkatakrishnan, A.J, Laeremans, T, Feinberg, E.N, Sanborn, A.L, Kato, H.E, Livingston, K.E, Thorsen, T.S, Kling, R, Granier, S, Gmeiner, P, Husbands, S.M, Traynor, J.R, Weis, W.I, Steyaert, J, Dror, R.O, Kobilka, B.K. | Deposit date: | 2015-06-15 | Release date: | 2015-08-05 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | Structural insights into mu-opioid receptor activation. Nature, 524, 2015
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5CJ3
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![BU of 5cj3 by Molmil](/molmil-images/mine/5cj3) | Crystal structure of the zorbamycin binding protein (ZbmA) from Streptomyces flavoviridis with zorbamycin | Descriptor: | CHLORIDE ION, COPPER (II) ION, Zbm binding protein, ... | Authors: | Chang, C, Bigelow, L, Clancy, S, Babnigg, G, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Rudolf, J.D, Ma, M, Chang, C.-Y, Lohman, J.R, Yang, D, Shen, B, Enzyme Discovery for Natural Product Biosynthesis, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | Deposit date: | 2015-07-13 | Release date: | 2015-07-22 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.6499 Å) | Cite: | Crystal Structure of the Zorbamycin-Binding Protein ZbmA, the Primary Self-Resistance Element in Streptomyces flavoviridis ATCC21892. Biochemistry, 54, 2015
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5C7J
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![BU of 5c7j by Molmil](/molmil-images/mine/5c7j) | CRYSTAL STRUCTURE OF NEDD4 WITH A UB VARIANT | Descriptor: | E3 ubiquitin-protein ligase NEDD4, Polyubiquitin-C | Authors: | Walker, J.R, Hu, J, Dong, A, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Tong, Y, Structural Genomics Consortium (SGC) | Deposit date: | 2015-06-24 | Release date: | 2016-03-16 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes. Mol.Cell, 62, 2016
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3OS5
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![BU of 3os5 by Molmil](/molmil-images/mine/3os5) | SET7/9-Dnmt1 K142me1 complex | Descriptor: | 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, Dnmt1, ... | Authors: | Esteve, P.-O, Chang, Y, Samaranayake, M, Upadhyay, A.K, Horton, J.R, Feehery, G.R, Cheng, X, Pradhan, S. | Deposit date: | 2010-09-08 | Release date: | 2010-12-15 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | A methylation and phosphorylation switch between an adjacent lysine and serine determines human DNMT1 stability. Nat.Struct.Mol.Biol., 18, 2011
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3MKH
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![BU of 3mkh by Molmil](/molmil-images/mine/3mkh) | Podospora anserina Nitroalkane Oxidase | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION, NITROALKANE OXIDASE, ... | Authors: | Tormos, J.R, Taylor, A.B, Daubner, S.C, Hart, P.J, Fitzpatrick, P.F. | Deposit date: | 2010-04-14 | Release date: | 2010-06-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.995 Å) | Cite: | Identification of a hypothetical protein from Podospora anserina as a nitroalkane oxidase. Biochemistry, 49, 2010
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5CEH
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![BU of 5ceh by Molmil](/molmil-images/mine/5ceh) | Structure of histone lysine demethylase KDM5A in complex with selective inhibitor | Descriptor: | 7-oxo-5-phenyl-6-(propan-2-yl)-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile, Lysine-specific demethylase 5A, NICKEL (II) ION, ... | Authors: | Kiefer, J.R, Vinogradova, M. | Deposit date: | 2015-07-06 | Release date: | 2016-05-18 | Last modified: | 2017-11-22 | Method: | X-RAY DIFFRACTION (3.14 Å) | Cite: | An inhibitor of KDM5 demethylases reduces survival of drug-tolerant cancer cells. Nat.Chem.Biol., 12, 2016
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3K6T
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![BU of 3k6t by Molmil](/molmil-images/mine/3k6t) | Crystal structure of the GLD-1 homodimerization domain from Caenorhabditis elegans at 2.04 A resolution | Descriptor: | Female germline-specific tumor suppressor gld-1 | Authors: | Beuck, C, Szymczyna, B.R, Kerkow, D.E, Carmel, A.B, Columbus, L, Stanfield, R.L, Williamson, J.R. | Deposit date: | 2009-10-09 | Release date: | 2010-03-09 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Structure of the GLD-1 homodimerization domain: insights into STAR protein-mediated translational regulation. Structure, 18, 2010
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5CEI
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![BU of 5cei by Molmil](/molmil-images/mine/5cei) | Crystal structure of CDK8:Cyclin C complex with compound 22 | Descriptor: | 1,2-ETHANEDIOL, 4-(4-iodophenoxy)-N-methylthieno[2,3-c]pyridine-2-carboxamide, Cyclin-C, ... | Authors: | Kiefer, J.R, Schneider, E.V, Maskos, K, Koehler, M.F.T. | Deposit date: | 2015-07-06 | Release date: | 2016-02-10 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.24 Å) | Cite: | Development of a Potent, Specific CDK8 Kinase Inhibitor Which Phenocopies CDK8/19 Knockout Cells. Acs Med.Chem.Lett., 7, 2016
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5CHH
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![BU of 5chh by Molmil](/molmil-images/mine/5chh) | Crystal structure of transcriptional regulator CdpR from Pseudomonas aeruginosa | Descriptor: | AraC family transcriptional regulator | Authors: | Zhao, J.R, Yu, X, Zhu, M, Kang, H.P, Kong, W.N, Ma, J.B, Deng, X, Gan, J.H, Liang, H.H. | Deposit date: | 2015-07-10 | Release date: | 2016-05-18 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural and Molecular Mechanism of CdpR Involved in Quorum-Sensing and Bacterial Virulence in Pseudomonas aeruginosa Plos Biol., 14, 2016
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5CT9
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![BU of 5ct9 by Molmil](/molmil-images/mine/5ct9) | G158E/K44E/R57E/Y49E Bacillus subtilis lipase A with 5% [BMIM][Cl] | Descriptor: | 1-butyl-3-methyl-1H-imidazol-3-ium, CHLORIDE ION, Esterase | Authors: | Nordwald, E.M, Plaks, J.G, Snell, J.R, Sousa, M.C, Kaar, J.L. | Deposit date: | 2015-07-23 | Release date: | 2015-11-04 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Crystallographic Investigation of Imidazolium Ionic Liquid Effects on Enzyme Structure. Chembiochem, 16, 2015
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3J3Q
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![BU of 3j3q by Molmil](/molmil-images/mine/3j3q) | |
5CRI
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![BU of 5cri by Molmil](/molmil-images/mine/5cri) | Wild-type Bacillus subtilis lipase A with 0% [BMIM][Cl] | Descriptor: | Esterase, SULFATE ION | Authors: | Nordwald, E.M, Plaks, J.G, Snell, J.R, Sousa, M.C, Kaar, J.L. | Deposit date: | 2015-07-22 | Release date: | 2015-11-04 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Crystallographic Investigation of Imidazolium Ionic Liquid Effects on Enzyme Structure. Chembiochem, 16, 2015
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5CT6
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![BU of 5ct6 by Molmil](/molmil-images/mine/5ct6) | Wild-type Bacillus subtilis lipase A with 20% [BMIM][Cl] | Descriptor: | 1-butyl-3-methyl-1H-imidazol-3-ium, CHLORIDE ION, Lipase EstA | Authors: | Nordwald, E.M, Plaks, J.G, Snell, J.R, Sousa, M.C, Kaar, J.L. | Deposit date: | 2015-07-23 | Release date: | 2015-11-04 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.902 Å) | Cite: | Crystallographic Investigation of Imidazolium Ionic Liquid Effects on Enzyme Structure. Chembiochem, 16, 2015
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5CT8
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![BU of 5ct8 by Molmil](/molmil-images/mine/5ct8) | G158E/K44E/R57E/Y49E Bacillus subtilis lipase A with 0% [BMIM][Cl] | Descriptor: | Quadruple mutant lipase A, SULFATE ION | Authors: | Nordwald, E.M, Plaks, J.G, Snell, J.R, Sousa, M.C, Kaar, J.L. | Deposit date: | 2015-07-23 | Release date: | 2015-11-04 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.29 Å) | Cite: | Crystallographic Investigation of Imidazolium Ionic Liquid Effects on Enzyme Structure. Chembiochem, 16, 2015
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3P8D
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![BU of 3p8d by Molmil](/molmil-images/mine/3p8d) | Crystal structure of the second Tudor domain of human PHF20 (homodimer form) | Descriptor: | Medulloblastoma antigen MU-MB-50.72 | Authors: | Cui, G, Lee, J, Thompson, J.R, Botuyan, M.V, Mer, G. | Deposit date: | 2010-10-13 | Release date: | 2011-06-22 | Last modified: | 2012-09-26 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | PHF20 is an effector protein of p53 double lysine methylation that stabilizes and activates p53. Nat.Struct.Mol.Biol., 19, 2012
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5CT4
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![BU of 5ct4 by Molmil](/molmil-images/mine/5ct4) | Wild-type Bacillus subtilis lipase A with 5% [BMIM][Cl] | Descriptor: | 1-butyl-3-methyl-1H-imidazol-3-ium, CHLORIDE ION, Esterase, ... | Authors: | Nordwald, E.M, Plaks, J.G, Snell, J.R, Sousa, M.C, Kaar, J.L. | Deposit date: | 2015-07-23 | Release date: | 2015-11-04 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.49 Å) | Cite: | Crystallographic Investigation of Imidazolium Ionic Liquid Effects on Enzyme Structure. Chembiochem, 16, 2015
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3MVD
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![BU of 3mvd by Molmil](/molmil-images/mine/3mvd) | Crystal structure of the chromatin factor RCC1 in complex with the nucleosome core particle | Descriptor: | DNA (146-MER), Histone H2A, Histone H2B 1.1, ... | Authors: | Makde, R.D, England, J.R, Yennawar, H.P, Tan, S. | Deposit date: | 2010-05-04 | Release date: | 2010-08-25 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure of RCC1 chromatin factor bound to the nucleosome core particle. Nature, 467, 2010
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5CUR
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![BU of 5cur by Molmil](/molmil-images/mine/5cur) | G158E/K44E/R57E/Y49E Bacillus subtilis lipase A with 20% [BMIM][Cl] | Descriptor: | 1-butyl-3-methyl-1H-imidazol-3-ium, CHLORIDE ION, Esterase | Authors: | Nordwald, E.M, Plaks, J.G, Snell, J.R, Sousa, M.C, Kaar, J.L. | Deposit date: | 2015-07-24 | Release date: | 2015-11-04 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.302 Å) | Cite: | Crystallographic Investigation of Imidazolium Ionic Liquid Effects on Enzyme Structure. Chembiochem, 16, 2015
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5CXS
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![BU of 5cxs by Molmil](/molmil-images/mine/5cxs) | Crystal Structure of Isoform 2 of Purine Nucleoside Phosphorylase complexed with MES | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Purine nucleoside phosphorylase | Authors: | Torini, J.R, Romanello, L, Bird, L, Owens, R, Brandao-Neto, J, Pereira, H.M. | Deposit date: | 2015-07-29 | Release date: | 2016-08-03 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | The molecular structure of Schistosoma mansoni PNP isoform 2 provides insights into the nucleoside selectivity of PNPs. PLoS ONE, 13, 2018
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