1GEA
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![BU of 1gea by Molmil](/molmil-images/mine/1gea) | RECEPTOR-BOUND CONFORMATION OF PACAP21 | Descriptor: | PITUITARY ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE | Authors: | Inooka, H, Ohtaki, T, Kitahara, O, Ikegami, T, Endo, S, Kitada, C, Ogi, K, Onda, H, Fujino, M, Shirakawa, M. | Deposit date: | 2000-10-20 | Release date: | 2001-04-20 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Conformation of a peptide ligand bound to its G-protein coupled receptor. Nat.Struct.Biol., 8, 2001
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6I0V
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![BU of 6i0v by Molmil](/molmil-images/mine/6i0v) | Crystal structure of DmTailor in complex with CACAGU RNA | Descriptor: | MAGNESIUM ION, RNA (5'-R(*CP*AP*CP*AP*GP*U)-3'), Terminal uridylyltransferase Tailor | Authors: | Kroupova, A, Ivascu, A, Jinek, M. | Deposit date: | 2018-10-26 | Release date: | 2018-12-05 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.851 Å) | Cite: | Structural basis for acceptor RNA substrate selectivity of the 3' terminal uridylyl transferase Tailor. Nucleic Acids Res., 47, 2019
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6I0S
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![BU of 6i0s by Molmil](/molmil-images/mine/6i0s) | Crystal structure of DmTailor in complex with UMPNPP | Descriptor: | 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, MAGNESIUM ION, Terminal uridylyltransferase Tailor | Authors: | Kroupova, A, Ivascu, A, Jinek, M. | Deposit date: | 2018-10-26 | Release date: | 2018-12-05 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural basis for acceptor RNA substrate selectivity of the 3' terminal uridylyl transferase Tailor. Nucleic Acids Res., 47, 2019
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6I0T
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![BU of 6i0t by Molmil](/molmil-images/mine/6i0t) | Crystal structure of DmTailor in complex with GpU | Descriptor: | RNA (5'-R(*GP*U)-3'), Terminal uridylyltransferase Tailor | Authors: | Kroupova, A, Ivascu, A, Jinek, M. | Deposit date: | 2018-10-26 | Release date: | 2018-12-05 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for acceptor RNA substrate selectivity of the 3' terminal uridylyl transferase Tailor. Nucleic Acids Res., 47, 2019
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6I0U
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![BU of 6i0u by Molmil](/molmil-images/mine/6i0u) | Crystal structure of DmTailor in complex with U6 RNA | Descriptor: | MAGNESIUM ION, RNA (5'-R(*UP*UP*UP*U)-3'), Terminal uridylyltransferase Tailor | Authors: | Kroupova, A, Ivascu, A, Jinek, M. | Deposit date: | 2018-10-26 | Release date: | 2018-12-05 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.001 Å) | Cite: | Structural basis for acceptor RNA substrate selectivity of the 3' terminal uridylyl transferase Tailor. Nucleic Acids Res., 47, 2019
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6RW0
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![BU of 6rw0 by Molmil](/molmil-images/mine/6rw0) | Crystal structure of ANGEL2, a 2',3'-cyclic phosphatase | Descriptor: | GLYCEROL, MAGNESIUM ION, POTASSIUM ION, ... | Authors: | Kroupova, A, Jinek, M. | Deposit date: | 2019-06-03 | Release date: | 2020-05-20 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | ANGEL2 is a member of the CCR4 family of deadenylases with 2',3'-cyclic phosphatase activity. Science, 369, 2020
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6QZK
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![BU of 6qzk by Molmil](/molmil-images/mine/6qzk) | Structure of Clostridium butyricum Argonaute bound to a guide DNA (5' deoxycytidine) and a 19-mer target DNA | Descriptor: | Clostridium butyricum Argonaute, DNA target (5'-D(T*AP*TP*AP*CP*AP*AP*CP*CP*TP*AP*CP*TP*AP*CP*CP*TP*CP*T)-3'), FORMIC ACID, ... | Authors: | Swarts, D.C, Jinek, M, Hegge, J.W, Van der Oost, J. | Deposit date: | 2019-03-11 | Release date: | 2019-04-24 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.548 Å) | Cite: | DNA-guided DNA cleavage at moderate temperatures by Clostridium butyricum Argonaute. Nucleic Acids Res., 47, 2019
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6RVZ
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![BU of 6rvz by Molmil](/molmil-images/mine/6rvz) | Crystal structure of ANGEL2, a 2',3'-cyclic phosphatase, in complex with adenosine-2',3'-vanadate | Descriptor: | ADENOSINE, MAGNESIUM ION, POTASSIUM ION, ... | Authors: | Kroupova, A, Jinek, M. | Deposit date: | 2019-06-03 | Release date: | 2020-05-20 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | ANGEL2 is a member of the CCR4 family of deadenylases with 2',3'-cyclic phosphatase activity. Science, 369, 2020
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5AF2
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![BU of 5af2 by Molmil](/molmil-images/mine/5af2) | |
3ICQ
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![BU of 3icq by Molmil](/molmil-images/mine/3icq) | Karyopherin nuclear state | Descriptor: | Exportin-T, GTP-binding nuclear protein GSP1/CNR1, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Cook, A.G, Fukuhara, N, Jinek, M, Conti, E. | Deposit date: | 2009-07-18 | Release date: | 2009-08-25 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structures of the tRNA export factor in the nuclear and cytosolic states Nature, 461, 2009
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3IBV
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![BU of 3ibv by Molmil](/molmil-images/mine/3ibv) | Karyopherin cytosolic state | Descriptor: | CALCIUM ION, Exportin-T | Authors: | Cook, A.G, Fukuhara, N, Jinek, M, Conti, E. | Deposit date: | 2009-07-17 | Release date: | 2009-08-25 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structures of the tRNA export factor in the nuclear and cytosolic states Nature, 461, 2009
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1WS8
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![BU of 1ws8 by Molmil](/molmil-images/mine/1ws8) | Crystal Structure of Mavicyanin from Cucurbita pepo medullosa (Zucchini) | Descriptor: | COPPER (II) ION, GLYCEROL, mavicyanin | Authors: | Xie, Y, Inoue, T, Miyamoto, Y, Matsumura, H, Kunishige, K, Yamaguchi, K, Nojini, M, Suzuki, S, Kai, Y. | Deposit date: | 2004-11-02 | Release date: | 2004-11-23 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural reorganization of the copper binding site involving Thr15 of mavicyanin from Cucurbita pepo medullosa (zucchini) upon reduction. J.Biochem.(Tokyo), 137, 2005
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2Y8Y
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![BU of 2y8y by Molmil](/molmil-images/mine/2y8y) | |
2Y8W
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![BU of 2y8w by Molmil](/molmil-images/mine/2y8w) | |
2Y9H
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![BU of 2y9h by Molmil](/molmil-images/mine/2y9h) | |
5FW2
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![BU of 5fw2 by Molmil](/molmil-images/mine/5fw2) | Crystal structure of SpCas9 variant EQR bound to sgRNA and TGAG PAM target DNA | Descriptor: | CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, MAGNESIUM ION, NON-TARGET DNA STRAND, ... | Authors: | Anders, C, Bargsten, K, Jinek, M. | Deposit date: | 2016-02-11 | Release date: | 2016-06-15 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.676 Å) | Cite: | Structural Plasticity of Pam Recognition by Engineered Variants of the RNA-Guided Endonuclease Cas9. Mol.Cell, 61, 2016
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5NG6
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![BU of 5ng6 by Molmil](/molmil-images/mine/5ng6) | |
5FW1
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![BU of 5fw1 by Molmil](/molmil-images/mine/5fw1) | Crystal structure of SpyCas9 variant VQR bound to sgRNA and TGAG PAM target DNA | Descriptor: | CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, MAGNESIUM ION, NON-TARGET DNA STRAND, ... | Authors: | Anders, C, Bargsten, K, Jinek, M. | Deposit date: | 2016-02-11 | Release date: | 2016-04-20 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.499 Å) | Cite: | Structural Plasticity of Pam Recognition by Engineered Variants of the RNA-Guided Endonuclease Cas9. Mol.Cell, 61, 2016
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1WS7
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![BU of 1ws7 by Molmil](/molmil-images/mine/1ws7) | Crystal Structure of Mavicyanin from Cucurbita pepo medullosa (Zucchini) | Descriptor: | COPPER (I) ION, Mavicyanin | Authors: | Xie, Y, Inoue, T, Miyamoto, Y, Matsumura, H, Kataoka, K, Yamaguchi, K, Nojini, M, Suzuki, S, Kai, Y. | Deposit date: | 2004-11-02 | Release date: | 2004-11-23 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural reorganization of the copper binding site involving Thr15 of mavicyanin from Cucurbita pepo medullosa (zucchini) upon reduction. J.Biochem.(Tokyo), 137, 2005
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5NFV
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![BU of 5nfv by Molmil](/molmil-images/mine/5nfv) | Crystal structure of catalytically inactive FnCas12 mutant bound to an R-loop structure containing a pre-crRNA mimic and full-length DNA target | Descriptor: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CRISPR-associated endonuclease Cpf1, DNA non-target strand, ... | Authors: | Swarts, D.C, van der Oost, J, Jinek, M. | Deposit date: | 2017-03-16 | Release date: | 2017-06-14 | Method: | X-RAY DIFFRACTION (2.501 Å) | Cite: | Structural Basis for Guide RNA Processing and Seed-Dependent DNA Targeting by CRISPR-Cas12a. Mol. Cell, 66, 2017
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2XLI
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![BU of 2xli by Molmil](/molmil-images/mine/2xli) | Crystal structure of the Csy4-crRNA complex, monoclinic form | Descriptor: | 5'-R(*CP*UP*GP*CP*CP*GP*UP*AP*UP*AP*GP*GP*CP*A*DG*C)-3', CSY4 ENDORIBONUCLEASE | Authors: | Haurwitz, R.E, Jinek, M, Wiedenheft, B, Zhou, K, Doudna, J.A. | Deposit date: | 2010-07-20 | Release date: | 2010-09-22 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.33 Å) | Cite: | Sequence- and Structure-Specific RNA Processing by a Crispr Endonuclease. Science, 329, 2010
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5FSH
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![BU of 5fsh by Molmil](/molmil-images/mine/5fsh) | |
2XLJ
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![BU of 2xlj by Molmil](/molmil-images/mine/2xlj) | Crystal structure of the Csy4-crRNA complex, hexagonal form | Descriptor: | 5'-R(*CP*UP*GP*CP*CP*GP*UP*AP*UP*AP*GP*GP*CP*A*DG*C)-3', CSY4 ENDORIBONUCLEASE | Authors: | Haurwitz, R.E, Jinek, M, Wiedenheft, B, Zhou, K, Doudna, J.A. | Deposit date: | 2010-07-20 | Release date: | 2010-09-22 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Sequence- and Structure-Specific RNA Processing by a Crispr Endonuclease. Science, 329, 2010
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2XLK
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![BU of 2xlk by Molmil](/molmil-images/mine/2xlk) | Crystal structure of the Csy4-crRNA complex, orthorhombic form | Descriptor: | 5'-R(*CP*UP*GP*CP*CP*GP*UP*AP*UP*AP*GP*GP*CP*A*DG*C)-3', CSY4 ENDORIBONUCLEASE | Authors: | Haurwitz, R.E, Jinek, M, Wiedenheft, B, Zhou, K, Doudna, J.A. | Deposit date: | 2010-07-21 | Release date: | 2010-09-22 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.805 Å) | Cite: | Sequence- and Structure-Specific RNA Processing by a Crispr Endonuclease. Science, 329, 2010
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5FW3
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![BU of 5fw3 by Molmil](/molmil-images/mine/5fw3) | Crystal structure of SpCas9 variant VRER bound to sgRNA and TGCG PAM target DNA | Descriptor: | CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, MAGNESIUM ION, NON-TARGET DNA STRAND, ... | Authors: | Anders, C, Bargsten, K, Jinek, M. | Deposit date: | 2016-02-11 | Release date: | 2016-06-15 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural Plasticity of Pam Recognition by Engineered Variants of the RNA-Guided Endonuclease Cas9. Mol.Cell, 61, 2016
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