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3DC3
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BU of 3dc3 by Molmil
Use of Carbonic Anhydrase II, IX Active-Site Mimic, for the Purpose of Screening Inhibitors for Possible Anti-Cancer Properties
Descriptor: 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, Carbonic anhydrase 2, ZINC ION
Authors:Genis, C, Sippel, K.H, Case, N, Govindasamy, L, Agbandje-Mckenna, M, Mckenna, R.
Deposit date:2008-06-03
Release date:2009-03-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Design of a carbonic anhydrase IX active-site mimic to screen inhibitors for possible anticancer properties
Biochemistry, 48, 2009
3DC9
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BU of 3dc9 by Molmil
Use of Carbonic Anhydrase II, IX Active-Site Mimic, for the Purpose of Screening Inhibitors for Possible Anti-Cancer Properties
Descriptor: Carbonic anhydrase 2, ZINC ION
Authors:Genis, C, Sippel, K.H, Case, N, Govindasamy, L, Agbandje-Mckenna, M, Mckenna, R.
Deposit date:2008-06-03
Release date:2009-03-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Design of a carbonic anhydrase IX active-site mimic to screen inhibitors for possible anticancer properties
Biochemistry, 48, 2009
3D9Z
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BU of 3d9z by Molmil
Use of Carbonic Anhydrase II, IX Active-Site Mimic, for the Purpose of Screening Inhibitors for Possible Anti-Cancer Properties
Descriptor: 5-(2-chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide, Carbonic anhydrase 2, ZINC ION
Authors:Genis, C, Sippel, K.H, Case, N, Govindasamy, L, Agbandje-Mckenna, M, Mckenna, R.
Deposit date:2008-05-28
Release date:2009-03-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Design of a carbonic anhydrase IX active-site mimic to screen inhibitors for possible anticancer properties
Biochemistry, 48, 2009
3DCS
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BU of 3dcs by Molmil
Use of Carbonic Anhydrase II, IX Active-Site Mimic, for the Purpose of Screening Inhibitors for Possible Anti-Cancer Properties
Descriptor: Carbonic anhydrase 2, N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2(3H)-ylidene)acetamide, ZINC ION
Authors:Genis, C, Sippel, K.H, Case, N, Govindasamy, L, Agbandje-Mckenna, M, Mckenna, R.
Deposit date:2008-06-04
Release date:2009-03-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Design of a carbonic anhydrase IX active-site mimic to screen inhibitors for possible anticancer properties
Biochemistry, 48, 2009
3DCW
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BU of 3dcw by Molmil
Use of Carbonic Anhydrase II, IX Active-Site Mimic, for the Purpose of Screening Inhibitors for Possible Anti-Cancer Properties
Descriptor: 6-ethoxy-1,3-benzothiazole-2-sulfonamide, Carbonic anhydrase 2, ZINC ION
Authors:Genis, C, Sippel, K.H, Case, N, Govindasamy, L, Agbandje-Mckenna, M, Mckenna, R.
Deposit date:2008-06-04
Release date:2009-03-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Design of a carbonic anhydrase IX active-site mimic to screen inhibitors for possible anticancer properties
Biochemistry, 48, 2009
2ILI
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BU of 2ili by Molmil
Refine atomic structure of human carbonic anhydrase II
Descriptor: Carbonic anhydrase 2, ZINC ION
Authors:Fisher, S.Z.
Deposit date:2006-10-02
Release date:2007-06-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:Atomic crystal and molecular dynamics simulation structures of human carbonic anhydrase II: insights into the proton transfer mechanism
Biochemistry, 46, 2007
3E78
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BU of 3e78 by Molmil
Structure determination of the cancer-associated Mycoplasma hyorhinis protein Mh-p37
Descriptor: CALCIUM ION, CHLORIDE ION, High affinity transport system protein p37, ...
Authors:Sippel, K.H, Robbins, A.H, Reutzel, R, Domsic, J, McKenna, R.
Deposit date:2008-08-18
Release date:2008-10-21
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure determination of the cancer-associated Mycoplasma hyorhinis protein Mh-p37.
Acta Crystallogr.,Sect.D, 64, 2008
8TXO
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BU of 8txo by Molmil
E. coli DNA-directed RNA polymerase transcription elongation complex bound to the unnatural dZ-PTP base pair in the active site
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Aiyer, S, Shan, Z, Oh, J, Wang, D, Tan, Y.Z, Lyumkis, D.
Deposit date:2023-08-23
Release date:2024-01-24
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Overcoming resolution attenuation during tilted cryo-EM data collection.
Nat Commun, 15, 2024
7RL1
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BU of 7rl1 by Molmil
AAVrh.10-7x capsid
Descriptor: Capsid protein VP1, DNA (5'-D(*CP*A)-3')
Authors:Mietzsch, M, McKenna, R.
Deposit date:2021-07-23
Release date:2021-09-08
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (2.71 Å)
Cite:Structural Study of Aavrh.10 Receptor and Antibody Interactions.
J.Virol., 95, 2021
7S1W
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BU of 7s1w by Molmil
The AAVrh.10-glycan complex
Descriptor: Capsid protein VP1, beta-D-galactopyranose
Authors:Mietzsch, M, McKenna, R.
Deposit date:2021-09-02
Release date:2021-09-22
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.09 Å)
Cite:Structural Study of Aavrh.10 Receptor and Antibody Interactions.
J.Virol., 95, 2021
4XZ5
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BU of 4xz5 by Molmil
Structure of the thermostable alpha-Carbonic Anydrase from Thiomicrospira crunogena XCL-2 gammaproteobacterium
Descriptor: BICARBONATE ION, Carbonic anhydrase, alpha family, ...
Authors:Mahon, B.P, Diaz-Torres, N.A, Pinard, M.A, McKenna, R.
Deposit date:2015-02-03
Release date:2015-07-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.596 Å)
Cite:Structural and biophysical characterization of the alpha-carbonic anhydrase from the gammaproteobacterium Thiomicrospira crunogena XCL-2: insights into engineering thermostable enzymes for CO2 sequestration.
Acta Crystallogr.,Sect.D, 71, 2015
5DVX
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BU of 5dvx by Molmil
Crystal structure of the catalytic-domain of human carbonic anhydrase IX at 1.6 angstrom resolution
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, Carbonic anhydrase 9, ...
Authors:Mahon, B.P, Socorro, L, Driscoll, J.M, McKenna, R.
Deposit date:2015-09-21
Release date:2016-08-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.598 Å)
Cite:The Structure of Carbonic Anhydrase IX Is Adapted for Low-pH Catalysis.
Biochemistry, 55, 2016
7U97
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BU of 7u97 by Molmil
SAAV pH 4.0 capsid structure
Descriptor: Capsid protein
Authors:Mietzsch, M, McKenna, R.
Deposit date:2022-03-10
Release date:2022-04-13
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (2.66 Å)
Cite:Characterization of the Serpentine Adeno-Associated Virus (SAAV) Capsid Structure: Receptor Interactions and Antigenicity.
J.Virol., 96, 2022
7U95
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BU of 7u95 by Molmil
SAAV pH 6.0 capsid structure
Descriptor: Capsid protein
Authors:Mietzsch, M, McKenna, R.
Deposit date:2022-03-10
Release date:2022-04-13
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (2.73 Å)
Cite:Characterization of the Serpentine Adeno-Associated Virus (SAAV) Capsid Structure: Receptor Interactions and Antigenicity.
J.Virol., 96, 2022
7U96
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BU of 7u96 by Molmil
SAAV pH 5.5 capsid structure
Descriptor: Capsid protein
Authors:Mietzsch, M, McKenna, R.
Deposit date:2022-03-10
Release date:2022-04-13
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (2.14 Å)
Cite:Characterization of the Serpentine Adeno-Associated Virus (SAAV) Capsid Structure: Receptor Interactions and Antigenicity.
J.Virol., 96, 2022
7U94
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BU of 7u94 by Molmil
SAAV pH 7.4 capsid structure
Descriptor: Capsid protein
Authors:Mietzsch, M, McKenna, R.
Deposit date:2022-03-10
Release date:2022-04-13
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (3.25 Å)
Cite:Characterization of the Serpentine Adeno-Associated Virus (SAAV) Capsid Structure: Receptor Interactions and Antigenicity.
J.Virol., 96, 2022
1G0E
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BU of 1g0e by Molmil
SITE-SPECIFIC MUTANT (HIS64 REPLACED WITH ALA) OF HUMAN CARBONIC ANHYDRASE II COMPLEXED WITH 4-METHYLIMIDAZOLE
Descriptor: 4-METHYLIMIDAZOLE, CARBONIC ANHYDRASE II, MERCURY (II) ION, ...
Authors:Duda, D, McKenna, R.
Deposit date:2000-10-06
Release date:2000-10-18
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural and kinetic analysis of the chemical rescue of the proton transfer function of carbonic anhydrase II.
Biochemistry, 40, 2001
1G0F
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BU of 1g0f by Molmil
SITE-SPECIFIC MUTANT (HIS64 REPLACED WITH ALA) OF HUMAN CARBONIC ANHYDRASE II
Descriptor: CARBONIC ANHYDRASE II, MERCURY (II) ION, ZINC ION
Authors:Duda, D, McKenna, R.
Deposit date:2000-10-06
Release date:2000-10-18
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural and kinetic analysis of the chemical rescue of the proton transfer function of carbonic anhydrase II.
Biochemistry, 40, 2001
3EKI
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BU of 3eki by Molmil
Structural insights of the Mycoplasma hyorhinis protein Mh-p37: A putative thiamine pyrophosphate transporter
Descriptor: BROMIDE ION, CALCIUM ION, GLYCEROL, ...
Authors:Sippel, K.H, Robbins, A.H, Reutzel, R, McKenna, R.
Deposit date:2008-09-19
Release date:2009-06-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural insights into the extracytoplasmic thiamine-binding lipoprotein p37 of Mycoplasma hyorhinis
J.Bacteriol., 191, 2009
3IXO
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BU of 3ixo by Molmil
Crystal Structure of uncomplexed HIV_1 Protease Subtype A
Descriptor: HIV-1 protease
Authors:Robbins, A, McKenna, R.
Deposit date:2009-09-04
Release date:2010-03-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of the unbound form of HIV-1 subtype A protease: comparison with unbound forms of proteases from other HIV subtypes.
Acta Crystallogr.,Sect.D, 66, 2010
1KVP
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BU of 1kvp by Molmil
STRUCTURAL ANALYSIS OF THE SPIROPLASMA VIRUS, SPV4, IMPLICATIONS FOR EVOLUTIONARY VARIATION TO OBTAIN HOST DIVERSITY AMONG THE MICROVIRIDAE, ELECTRON MICROSCOPY, ALPHA CARBONS ONLY
Descriptor: SPV4 CAPSID PROTEIN VP1
Authors:McKenna, R.
Deposit date:1997-12-12
Release date:1999-02-23
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (27 Å)
Cite:Structural analysis of the Spiroplasma virus, SpV4: implications for evolutionary variation to obtain host diversity among the Microviridae.
Structure, 6, 1998
7NA6
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BU of 7na6 by Molmil
Cryo-EM structure of AAV True Type
Descriptor: Capsid protein VP1
Authors:Bennett, A.D, McKenna, R.
Deposit date:2021-06-19
Release date:2021-09-29
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:Comparative structural, biophysical, and receptor binding study of true type and wild type AAV2.
J.Struct.Biol., 213, 2021
3V3H
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BU of 3v3h by Molmil
Kinetic and structural studies of thermostabilized mutants of HCA II.
Descriptor: CHLORIDE ION, Carbonic anhydrase 2, ZINC ION
Authors:Boone, C.D, Fisher, S.Z, McKenna, R.
Deposit date:2011-12-13
Release date:2012-06-20
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Kinetic and structural characterization of thermostabilized mutants of human carbonic anhydrase II.
Protein Eng.Des.Sel., 25, 2012
3GZ0
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BU of 3gz0 by Molmil
Apo-human carbonic anhydrase II revisited: Implications of the loss of a metal in protein structure, stability and solvent network
Descriptor: Carbonic anhydrase 2, ZINC ION
Authors:Avvaru, B.S, McKenna, R.
Deposit date:2009-04-06
Release date:2009-07-21
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.26 Å)
Cite:Apo-Human Carbonic Anhydrase II Revisited: Implications of the Loss of a Metal in Protein Structure, Stability, and Solvent Network .
Biochemistry, 48, 2009
1IJJ
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BU of 1ijj by Molmil
THE X-RAY CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN RABBIT SKELETAL MUSCLE ACTIN AND LATRUNCULIN A AT 2.85 A RESOLUTION
Descriptor: ACTIN, ALPHA SKELETAL MUSCLE, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Vorobiev, S.M, Bubb, M.R, Almo, S.C.
Deposit date:2001-04-26
Release date:2002-04-15
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Polylysine induces an antiparallel actin dimer that nucleates filament assembly: crystal structure at 3.5-A resolution
J.Biol.Chem., 277, 2002

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數據於2024-09-11公開中

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