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8FE5
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BU of 8fe5 by Molmil
Structure of J-PKAc chimera complexed with Aplithianine B
Descriptor: 6-[(6P)-6-(1-methyl-1H-imidazol-5-yl)-2,3-dihydro-4H-1,4-thiazin-4-yl]-7,9-dihydro-8H-purin-8-one, DnaJ homolog subfamily B member 1,cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha
Authors:Du, L, Wilson, B.A.P, Li, N, Martinez Fiesco, J.A, Dalilian, M, Wang, D, Smith, E.A, Wamiru, A, Goncharova, E.I, Zhang, P, O'Keefe, B.R.
Deposit date:2022-12-05
Release date:2023-10-18
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Discovery and Synthesis of a Naturally Derived Protein Kinase Inhibitor that Selectively Inhibits Distinct Classes of Serine/Threonine Kinases.
J.Nat.Prod., 86, 2023
8FAC
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BU of 8fac by Molmil
Structure of the leucine-rich repeat kinase 1 monomer
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 1
Authors:Metcalfe, R.D, Martinez Fiesco, J.A, Zhang, P.
Deposit date:2022-11-25
Release date:2023-08-16
Method:ELECTRON MICROSCOPY (3.92 Å)
Cite:Structure and regulation of full-length human leucine-rich repeat kinase 1.
Nat Commun, 14, 2023
8FEC
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BU of 8fec by Molmil
Structure of J-PKAc chimera complexed with Aplithianine derivative
Descriptor: 6-[(6P)-6-(4-bromo-1-methyl-1H-imidazol-5-yl)-2,3-dihydro-4H-1,4-thiazin-4-yl]-7H-purine, DnaJ homolog subfamily B member 1,cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha
Authors:Du, L, Wilson, B.A.P, Li, N, Martinez Fiesco, J.A, Dalilian, M, Wang, D, Smith, E.A, Wamiru, A, Goncharova, E.I, Zhang, P, O'Keefe, B.R.
Deposit date:2022-12-06
Release date:2023-10-18
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Discovery and Synthesis of a Naturally Derived Protein Kinase Inhibitor that Selectively Inhibits Distinct Classes of Serine/Threonine Kinases.
J.Nat.Prod., 86, 2023
8FE2
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BU of 8fe2 by Molmil
Structure of J-PKAc chimera complexed with Aplithianine A
Descriptor: 6-[(6M)-6-(1-methyl-1H-imidazol-5-yl)-2,3-dihydro-4H-1,4-thiazin-4-yl]-9H-purine, DnaJ homolog subfamily B member 1, cAMP-dependent protein kinase catalytic subunit alpha, ...
Authors:Du, L, Wilson, B.A.P, Li, N, Dalilian, M, Wang, D, Martinez Fiesco, J.A, Smith, E.A, Wamiru, A, Goncharova, E.I, Zhang, P, O'Keefe, B.R.
Deposit date:2022-12-05
Release date:2023-10-18
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Discovery and Synthesis of a Naturally Derived Protein Kinase Inhibitor that Selectively Inhibits Distinct Classes of Serine/Threonine Kinases.
J.Nat.Prod., 86, 2023
3H4M
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BU of 3h4m by Molmil
AAA ATPase domain of the proteasome- activating nucleotidase
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Proteasome-activating nucleotidase
Authors:Jeffrey, P, Zhang, F, Hu, M, Tian, G, Zhang, P, Finley, D, Shi, Y.
Deposit date:2009-04-20
Release date:2009-06-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.106 Å)
Cite:Structural Insights into the Regulatory Particle of the Proteasome from Methanocaldococcus jannaschii.
Mol.Cell, 34, 2009
6XF8
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BU of 6xf8 by Molmil
DLP 5 fold
Descriptor: Inner capsid protein lambda-1, Inner capsid protein sigma-2, Outer capsid protein mu-1, ...
Authors:Sutton, G, Sun, D.P, Fu, X.F, Kotecha, A, Hecksel, G.W, Clare, D.K, Zhang, P, Stuart, D, Boyce, M.
Deposit date:2020-06-15
Release date:2020-09-23
Method:ELECTRON MICROSCOPY (6.5 Å)
Cite:Assembly intermediates of orthoreovirus captured in the cell.
Nat Commun, 11, 2020
6Q0X
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BU of 6q0x by Molmil
The cryo-EM structure of the SNX-BAR Mvp1 tetramer
Descriptor: Sorting nexin MVP1
Authors:Sun, D, Ford, M.G.J, Zhang, P.
Deposit date:2019-08-02
Release date:2020-04-01
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:The cryo-EM structure of the SNX-BAR Mvp1 tetramer.
Nat Commun, 11, 2020
6KZ8
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BU of 6kz8 by Molmil
Crystal structure of plant Phospholipase D alpha complex with phosphatidic acid
Descriptor: 1,2-DIOCTANOYL-SN-GLYCERO-3-PHOSPHATE, CALCIUM ION, Phospholipase D alpha 1
Authors:Li, J.X, Yu, F, Zhang, P.
Deposit date:2019-09-23
Release date:2019-11-13
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.291 Å)
Cite:Crystal structure of plant PLD alpha 1 reveals catalytic and regulatory mechanisms of eukaryotic phospholipase D.
Cell Res., 30, 2020
6KZ9
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BU of 6kz9 by Molmil
Crystal structure of plant Phospholipase D alpha
Descriptor: CALCIUM ION, Phospholipase D alpha 1
Authors:Li, J.X, Yu, F, Zhang, P.
Deposit date:2019-09-23
Release date:2019-10-30
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:Crystal structure of plant PLD alpha 1 reveals catalytic and regulatory mechanisms of eukaryotic phospholipase D.
Cell Res., 30, 2020
8C9M
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BU of 8c9m by Molmil
HERV-K Gag immature lattice
Descriptor: Gag protein
Authors:Krebs, A.-S, Liu, H.-F, Zhou, Y, Rey, J.S, Levintov, L, Perilla, J.R, Bartesaghi, A, Zhang, P.
Deposit date:2023-01-23
Release date:2023-02-01
Last modified:2023-07-05
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Molecular architecture and conservation of an immature human endogenous retrovirus.
Biorxiv, 2023
6LZ7
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BU of 6lz7 by Molmil
Tetrameric structure of ZmCRY1a PHR domain
Descriptor: Cryptochrome-1, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Shao, K, Zhang, X, Zhang, P.
Deposit date:2020-02-18
Release date:2020-05-13
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.59936166 Å)
Cite:The oligomeric structures of plant cryptochromes.
Nat.Struct.Mol.Biol., 27, 2020
6LZ3
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BU of 6lz3 by Molmil
Structure of cryptochrome in active conformation
Descriptor: Cryptochrome2, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Shao, K, Zhang, X, Zhang, P.
Deposit date:2020-02-18
Release date:2020-04-29
Last modified:2020-11-11
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:The oligomeric structures of plant cryptochromes.
Nat.Struct.Mol.Biol., 27, 2020
8C5V
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BU of 8c5v by Molmil
Chemotaxis core signalling unit from E protein lysed E. coli cells
Descriptor: Chemotaxis protein CheA, Chemotaxis protein CheW, Methyl-accepting chemotaxis protein I
Authors:Cassidy, C.K, Qin, Z, Zhang, P.
Deposit date:2023-01-10
Release date:2023-09-13
Last modified:2023-11-29
Method:ELECTRON MICROSCOPY (12 Å)
Cite:Structure of the native chemotaxis core signaling unit from phage E-protein lysed E. coli cells.
Mbio, 14, 2023
2M6I
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BU of 2m6i by Molmil
Putative pentameric open-channel structure of full-length transmembrane domains of human glycine receptor alpha1 subunit
Descriptor: Full-Length Transmembrane Domains of Human Glycine Receptor alpha1 Subunit
Authors:Mowrey, D, Cui, T, Jia, Y, Ma, D, Makhov, A.M, Zhang, P, Tang, P, Xu, Y.
Deposit date:2013-03-29
Release date:2013-09-04
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Open-Channel Structures of the Human Glycine Receptor alpha 1 Full-Length Transmembrane Domain.
Structure, 21, 2013
2M6B
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BU of 2m6b by Molmil
Structure of full-length transmembrane domains of human glycine receptor alpha1 monomer subunit
Descriptor: Full-Length Transmembrane Domains of Human Glycine Receptor alpha1 Subunit
Authors:Mowrey, D, Cui, T, Jia, Y, Ma, D, Makhov, A.M, Zhang, P, Tang, P, Xu, Y.
Deposit date:2013-03-28
Release date:2013-09-04
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Open-Channel Structures of the Human Glycine Receptor alpha 1 Full-Length Transmembrane Domain.
Structure, 21, 2013
4XHR
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BU of 4xhr by Molmil
Structure of a phospholipid trafficking complex, native
Descriptor: Mitochondrial distribution and morphology protein 35, Protein UPS1, mitochondrial
Authors:Yu, F, He, F, Wang, C, Zhang, P.
Deposit date:2015-01-06
Release date:2015-07-01
Last modified:2015-08-05
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural basis of intramitochondrial phosphatidic acid transport mediated by Ups1-Mdm35 complex
Embo Rep., 16, 2015
3IWP
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BU of 3iwp by Molmil
Crystal structure of human copper homeostasis protein CutC
Descriptor: Copper homeostasis protein cutC homolog
Authors:Li, Y, Du, J, Zhang, P, Ding, J.
Deposit date:2009-09-03
Release date:2009-11-10
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of human copper homeostasis protein CutC reveals a potential copper-binding site
To be Published
4XIZ
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BU of 4xiz by Molmil
Structure of a phospholipid trafficking complex with substrate
Descriptor: 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, Mitochondrial distribution and morphology protein 35, Protein UPS1, ...
Authors:Yu, F, He, F, Wang, C, Zhang, P.
Deposit date:2015-01-08
Release date:2015-07-01
Last modified:2015-09-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis of intramitochondrial phosphatidic acid transport mediated by Ups1-Mdm35 complex
Embo Rep., 16, 2015
6SKM
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BU of 6skm by Molmil
Structure of the native full-length HIV-1 capsid protein A92E in helical assembly (-13,12)
Descriptor: Gag protein
Authors:Ni, T, Gerard, S, Zhao, G, Ning, J, Zhang, P.
Deposit date:2019-08-16
Release date:2020-08-26
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:Intrinsic curvature of the HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A.
Nat.Struct.Mol.Biol., 27, 2020
6SLQ
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BU of 6slq by Molmil
Structure of the native full-length HIV-1 capsid protein A92E in helical assembly (-12,11)
Descriptor: Gag protein
Authors:Ni, T, Gerard, S, Zhao, G, Ning, J, Zhang, P.
Deposit date:2019-08-20
Release date:2020-09-09
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Intrinsic curvature of the HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A.
Nat.Struct.Mol.Biol., 27, 2020
6SLU
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BU of 6slu by Molmil
Structure of the native full-length HIV-1 capsid protein A92E in helical assembly (-13,11)
Descriptor: Gag protein
Authors:Ni, T, Gerard, S, Zhao, G, Ning, J, Zhang, P.
Deposit date:2019-08-20
Release date:2020-09-09
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Intrinsic curvature of the HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A.
Nat.Struct.Mol.Biol., 27, 2020
6SMU
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BU of 6smu by Molmil
Structure of the native full-length HIV-1 capsid protein in helical assembly (-13,12)
Descriptor: Gag protein
Authors:Ni, T, Gerard, S, Zhao, G, Ning, J, Zhang, P.
Deposit date:2019-08-22
Release date:2020-09-09
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (5 Å)
Cite:Intrinsic curvature of the HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A.
Nat.Struct.Mol.Biol., 27, 2020
6SKN
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BU of 6skn by Molmil
Structure of the native full-length HIV-1 capsid protein in helical assembly (-13,8)
Descriptor: Gag protein
Authors:Ni, T, Gerard, S, Zhao, G, Ning, J, Zhang, P.
Deposit date:2019-08-16
Release date:2020-08-26
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Intrinsic curvature of the HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A.
Nat.Struct.Mol.Biol., 27, 2020
3J3Y
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BU of 3j3y by Molmil
Atomic-level structure of the entire HIV-1 capsid (186 hexamers + 12 pentamers)
Descriptor: capsid protein
Authors:Perilla, J.R, Zhao, G, Zhang, P, Schulten, K.J.
Deposit date:2013-05-06
Release date:2013-05-29
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY
Cite:Mature HIV-1 capsid structure by cryo-electron microscopy and all-atom molecular dynamics.
Nature, 497, 2013
6SKK
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BU of 6skk by Molmil
Structure of the native full-length HIV-1 capsid protein in helical assembly (-13,8)
Descriptor: capsid protein
Authors:Ni, T, Gerard, S, Zhao, G, Ning, J, Zhang, P.
Deposit date:2019-08-15
Release date:2020-08-26
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Intrinsic curvature of the HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A.
Nat.Struct.Mol.Biol., 27, 2020

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數據於2024-07-10公開中

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