4IB1
 
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4IB3
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3Q3Q
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7OBG
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7OBS
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7OB8
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7OBT
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7OBD
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7OBK
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7OBH
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7OBX
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7OB5
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7OBL
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7OBY
 | |
7OBC
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8IOI
 | | Crystal Structure of PadR- family transcriptional regulator Rv1176c from Mycobacterium tuberculosis H37Rv. | | Descriptor: | CHLORIDE ION, GLYCEROL, HEXAETHYLENE GLYCOL, ... | | Authors: | Yadav, V, Zohib, M, Pal, R.K, Biswal, B.K, Arora, A. | | Deposit date: | 2023-03-11 | | Release date: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.94 Å) | | Cite: | Structural and biophysical characterization of PadR family protein Rv1176c of Mycobacterium tuberculosis H37Rv.
Int.J.Biol.Macromol., 263, 2024
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9ERY
 | | Co-crystal strucutre of PD-L1 with low molecular weight inhibitor | | Descriptor: | 5-[[5-[[2-[bis(fluoranyl)methyl]-3-(2,3-dihydro-1,4-benzodioxin-6-yl)phenyl]methoxy]-2-[(2-hydroxyethylamino)methyl]phenoxy]methyl]pyridine-3-carbonitrile, Programmed cell death 1 ligand 1, SULFATE ION | | Authors: | Plewka, J, Magiera-Mularz, K, Zhang, W. | | Deposit date: | 2024-03-25 | | Release date: | 2024-07-24 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Design, synthesis, and evaluation of antitumor activity of 2-arylmethoxy-4-(2-fluoromethyl-biphenyl-3-ylmethoxy) benzylamine derivatives as PD-1/PD-l1 inhibitors.
Eur.J.Med.Chem., 276, 2024
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4XWH
 | | Crystal structure of the human N-acetyl-alpha-glucosaminidase | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-N-acetylglucosaminidase, ... | | Authors: | Birrane, G, Meiyappan, M, Dassier, A. | | Deposit date: | 2015-01-28 | | Release date: | 2016-02-03 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.32 Å) | | Cite: | Structural characterization of the alpha-N-acetylglucosaminidase, a key enzyme in the pathogenesis of Sanfilippo syndrome B.
J.Struct.Biol., 205, 2019
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6YGU
 | | Crystal structure of the minimal Mtr4-Red1 complex (single chain) from Chaetomium thermophilum | | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, ATP dependent RNA helicase (Dob1)-like protein, ... | | Authors: | Dobrev, N, Ahmed, Y.L, Sinning, I. | | Deposit date: | 2020-03-27 | | Release date: | 2021-05-05 | | Last modified: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (1.99 Å) | | Cite: | The zinc-finger protein Red1 orchestrates MTREC submodules and binds the Mtl1 helicase arch domain.
Nat Commun, 12, 2021
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6YFV
 | | Crystal structure of Mtr4-Red1 minimal complex from Chaetomium thermophilum | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ATP dependent RNA helicase (Dob1)-like protein, Red1, ... | | Authors: | Dobrev, N, Ahmed, Y.L, Sinning, I. | | Deposit date: | 2020-03-26 | | Release date: | 2021-05-05 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | The zinc-finger protein Red1 orchestrates MTREC submodules and binds the Mtl1 helicase arch domain.
Nat Commun, 12, 2021
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7Q72
 | | Structure of Pla1 in complex with Red1 | | Descriptor: | NURS complex subunit red1, Poly(A) polymerase pla1 | | Authors: | Soni, K, Wild, K, Sinning, I. | | Deposit date: | 2021-11-09 | | Release date: | 2022-12-07 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Mechanistic insights into RNA surveillance by the canonical poly(A) polymerase Pla1 of the MTREC complex.
Nat Commun, 14, 2023
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7Q73
 | | Structure of Pla1 apo | | Descriptor: | GLYCEROL, Poly(A) polymerase pla1 | | Authors: | Soni, K, Wild, K, Sinning, I. | | Deposit date: | 2021-11-09 | | Release date: | 2022-12-07 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Mechanistic insights into RNA surveillance by the canonical poly(A) polymerase Pla1 of the MTREC complex.
Nat Commun, 14, 2023
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7Q74
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4XMK
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4XML
 | | Crystal structure of Fab of HIV-1 gp120 V3-specific human monoclonal antibody 2424 | | Descriptor: | Heavy chain of HIV-1 gp120 V3-specific human monoclonal antibody 2424, Light chain of HIV-1 gp120 V3-specific human monoclonal antibody 2424 | | Authors: | Pan, R, Kong, X.-P. | | Deposit date: | 2015-01-14 | | Release date: | 2015-07-08 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.68 Å) | | Cite: | Functional and Structural Characterization of Human V3-Specific Monoclonal Antibody 2424 with Neutralizing Activity against HIV-1 JRFL.
J.Virol., 89, 2015
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